Stereochemistry of polypeptide chain configurations.

Modeling of loops in protein structures. Protein Sci (2000) 9.68

DNA sequence-dependent deformability deduced from protein-DNA crystal complexes. Proc Natl Acad Sci U S A (1998) 8.14

Optimization of the additive CHARMM all-atom protein force field targeting improved sampling of the backbone φ, ψ and side-chain χ(1) and χ(2) dihedral angles. J Chem Theory Comput (2012) 5.57

The nucleosomal core histone octamer at 3.1 A resolution: a tripartite protein assembly and a left-handed superhelix. Proc Natl Acad Sci U S A (1991) 4.76

Structure of the gene V protein of bacteriophage f1 determined by multiwavelength x-ray diffraction on the selenomethionyl protein. Proc Natl Acad Sci U S A (1994) 4.67

The 3-D structure of a zinc metallo-beta-lactamase from Bacillus cereus reveals a new type of protein fold. EMBO J (1995) 4.30

Enhanced protein thermostability from site-directed mutations that decrease the entropy of unfolding. Proc Natl Acad Sci U S A (1987) 3.85

A new generation of crystallographic validation tools for the protein data bank. Structure (2011) 3.41

The Flory isolated-pair hypothesis is not valid for polypeptide chains: implications for protein folding. Proc Natl Acad Sci U S A (2000) 3.39

QMEAN server for protein model quality estimation. Nucleic Acids Res (2009) 3.39

Minimization of polypeptide energy. I. Preliminary structures of bovine pancreatic ribonuclease S-peptide. Proc Natl Acad Sci U S A (1967) 3.26

The gramicidin A transmembrane channel: characteristics of head-to-head dimerized (L,D) helices. Proc Natl Acad Sci U S A (1971) 3.25

Stereochemical criteria for polypeptide and protein chain conformations. II. Allowed conformations for a pair of peptide units. Biophys J (1965) 3.25

Mutations in the tight-junction gene claudin 19 (CLDN19) are associated with renal magnesium wasting, renal failure, and severe ocular involvement. Am J Hum Genet (2006) 2.96

Reassessing random-coil statistics in unfolded proteins. Proc Natl Acad Sci U S A (2004) 2.93

Statistical potentials for fold assessment. Protein Sci (2002) 2.92

Stereochemical criteria for polypeptide and protein chain conformations. 3. Helical and hydrogen-bonded polypeptide chains. Biophys J (1966) 2.74

RNA structure comparison, motif search and discovery using a reduced representation of RNA conformational space. Nucleic Acids Res (2003) 2.42

Crystal structure of a translation termination complex formed with release factor RF2. Proc Natl Acad Sci U S A (2008) 2.33

The PDB_REDO server for macromolecular structure model optimization. IUCrJ (2014) 2.14

PDB_REDO: constructive validation, more than just looking for errors. Acta Crystallogr D Biol Crystallogr (2012) 2.08

A backbone-based theory of protein folding. Proc Natl Acad Sci U S A (2006) 2.00

Influence of non-bonded parameters on the quality of NMR structures: a new force field for NMR structure calculation. J Biomol NMR (1999) 1.96

Three-dimensional structure of human basic fibroblast growth factor. Proc Natl Acad Sci U S A (1991) 1.94

Crystal structure of casein kinase-1, a phosphate-directed protein kinase. EMBO J (1995) 1.78

Density Estimation for Protein Conformation Angles Using a Bivariate von Mises Distribution and Bayesian Nonparametrics. J Am Stat Assoc (2009) 1.78

X-ray structure of junctional adhesion molecule: structural basis for homophilic adhesion via a novel dimerization motif. EMBO J (2001) 1.75

Revisiting the Ramachandran plot: hard-sphere repulsion, electrostatics, and H-bonding in the alpha-helix. Protein Sci (2003) 1.73

STING Millennium: A web-based suite of programs for comprehensive and simultaneous analysis of protein structure and sequence. Nucleic Acids Res (2003) 1.64

Core structure of the U6 small nuclear ribonucleoprotein at 1.7-Å resolution. Nat Struct Mol Biol (2014) 1.56

Sampling realistic protein conformations using local structural bias. PLoS Comput Biol (2006) 1.56

Analysis of the code relating sequence to conformation in globular proteins. Development of a stereochemical alphabet on the basis of intra-residue information. Biochem J (1974) 1.56

Generalized hybrid-orbital method for combining density functional theory with molecular mechanicals. Chemphyschem (2005) 1.55

A knowledge-driven approach for crystallographic protein model completion. Acta Crystallogr D Biol Crystallogr (2008) 1.53

A novel method reveals that solvent water favors polyproline II over beta-strand conformation in peptides and unfolded proteins: conditional hydrophobic accessible surface area (CHASA). Protein Sci (2004) 1.52

A generative, probabilistic model of local protein structure. Proc Natl Acad Sci U S A (2008) 1.50

A simple model for polyproline II structure in unfolded states of alanine-based peptides. Protein Sci (2002) 1.46

Discrete RNA libraries from pseudo-torsional space. J Mol Biol (2012) 1.46

Evaluating and learning from RNA pseudotorsional space: quantitative validation of a reduced representation for RNA structure. J Mol Biol (2007) 1.45

Crystal structure of Penicillium citrinum P1 nuclease at 2.8 A resolution. EMBO J (1991) 1.44

The arabidopsis DNA polymerase δ has a role in the deposition of transcriptionally active epigenetic marks, development and flowering. PLoS Genet (2015) 1.42

iMolTalk: an interactive, internet-based protein structure analysis server. Nucleic Acids Res (2004) 1.41

Structure based sequence analysis & epitope prediction of gp41 HIV1 envelope glycoprotein isolated in Pakistan. Genet Vaccines Ther (2012) 1.41

New stochastic strategy to analyze helix folding. Biophys J (2002) 1.40

Structure-Activity Relationship Studies of N- and C-Terminally Modified Secretin Analogs for the Human Secretin Receptor. PLoS One (2016) 1.39

Identification of amino acids in the human tetherin transmembrane domain responsible for HIV-1 Vpu interaction and susceptibility. J Virol (2010) 1.37

Relationship between side chain structure and 14-helix stability of beta3-peptides in water. J Am Chem Soc (2005) 1.36

Redrawing the Ramachandran plot after inclusion of hydrogen-bonding constraints. Proc Natl Acad Sci U S A (2010) 1.29

Elucidating protein thermodynamics from the three-dimensional structure of the native state using network rigidity. Biophys J (2004) 1.28

Building native protein conformation from highly approximate backbone torsion angles. Proc Natl Acad Sci U S A (2005) 1.28

Structure and dynamics of calmodulin in solution. Biophys J (1998) 1.27

The intrinsic conformational propensities of the 20 naturally occurring amino acids and reflection of these propensities in proteins. Proc Natl Acad Sci U S A (2008) 1.26

Protein loop modeling by using fragment assembly and analytical loop closure. Proteins (2010) 1.25

Structural and functional analysis of laninamivir and its octanoate prodrug reveals group specific mechanisms for influenza NA inhibition. PLoS Pathog (2011) 1.25

Functionally relevant microsatellite markers from chickpea transcription factor genes for efficient genotyping applications and trait association mapping. DNA Res (2013) 1.22

Network rigidity at finite temperature: relationships between thermodynamic stability, the nonadditivity of entropy, and cooperativity in molecular systems. Phys Rev E Stat Nonlin Soft Matter Phys (2003) 1.20

Crystal structure of UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase from Escherichia coli. EMBO J (1997) 1.20

The Ramachandran plots of glycine and pre-proline. BMC Struct Biol (2005) 1.20

A Heterologous Multiepitope DNA Prime/Recombinant Protein Boost Immunisation Strategy for the Development of an Antiserum against Micrurus corallinus (Coral Snake) Venom. PLoS Negl Trop Dis (2016) 1.19

Stereoelectronic and steric effects in side chains preorganize a protein main chain. Proc Natl Acad Sci U S A (2009) 1.17

Validation of crystallographic models containing TLS or other descriptions of anisotropy. Acta Crystallogr D Biol Crystallogr (2010) 1.17

Using a conformation-dependent stereochemical library improves crystallographic refinement of proteins. Acta Crystallogr D Biol Crystallogr (2010) 1.17

Structure-Based Design of Inhibitors of Protein-Protein Interactions: Mimicking Peptide Binding Epitopes. Angew Chem Int Ed Engl (2015) 1.17

Generic coarse-grained model for protein folding and aggregation. J Chem Phys (2009) 1.13

Completeness of NOEs in protein structure: a statistical analysis of NMR. J Biomol NMR (1999) 1.13

The discovery of the alpha-helix and beta-sheet, the principal structural features of proteins. Proc Natl Acad Sci U S A (2003) 1.12

Polyproline II helix conformation in a proline-rich environment: a theoretical study. Biophys J (2004) 1.10

Structure and function of Humicola insolens family 6 cellulases: structure of the endoglucanase, Cel6B, at 1.6 A resolution. Biochem J (2000) 1.10

Crystal structure of human lithostathine, the pancreatic inhibitor of stone formation. EMBO J (1996) 1.10

Crystal structure of the catalytic core domain of the family 6 cellobiohydrolase II, Cel6A, from Humicola insolens, at 1.92 A resolution. Biochem J (1999) 1.09

Global mapping of nucleic acid conformational space: dinucleoside monophosphate conformations and transition pathways among conformational classes. Nucleic Acids Res (2003) 1.09

Reduced C(beta) statistical potentials can outperform all-atom potentials in decoy identification. Protein Sci (2007) 1.09

Analysis and validation of carbohydrate three-dimensional structures. Acta Crystallogr D Biol Crystallogr (2009) 1.08

Potential cooperations between odorant-binding proteins of the scarab beetle Holotrichia oblita Faldermann (Coleoptera: Scarabaeidae). PLoS One (2013) 1.08

Structure of Arabidopsis thaliana FUT1 Reveals a Variant of the GT-B Class Fold and Provides Insight into Xyloglucan Fucosylation. Plant Cell (2016) 1.07

EMRinger: side chain-directed model and map validation for 3D cryo-electron microscopy. Nat Methods (2015) 1.07

Estrogen receptor alpha somatic mutations Y537S and D538G confer breast cancer endocrine resistance by stabilizing the activating function-2 binding conformation. Elife (2016) 1.06

Continuous mutual improvement of macromolecular structure models in the PDB and of X-ray crystallographic software: the dual role of deposited experimental data. Acta Crystallogr D Biol Crystallogr (2014) 1.06

Chemical modifications in therapeutic protein aggregates generated under different stress conditions. J Biol Chem (2011) 1.05

The polyproline II conformation in short alanine peptides is noncooperative. Proc Natl Acad Sci U S A (2004) 1.05

Molecular modeling of family GH16 glycoside hydrolases: potential roles for xyloglucan transglucosylases/hydrolases in cell wall modification in the poaceae. Protein Sci (2004) 1.05

Crystal structure of levansucrase from the Gram-negative bacterium Gluconacetobacter diazotrophicus. Biochem J (2005) 1.05

On the occurrence of linear groups in proteins. Protein Sci (2009) 1.05

Structural basis of regiospecificity of a mononuclear iron enzyme in antibiotic fosfomycin biosynthesis. J Am Chem Soc (2011) 1.04

Folding very short peptides using molecular dynamics. PLoS Comput Biol (2006) 1.04

Protein conformational space in higher order phi-Psi maps. Proc Natl Acad Sci U S A (2005) 1.03

High-resolution structure of the native histone octamer. Acta Crystallogr Sect F Struct Biol Cryst Commun (2005) 1.02

The active site of O-acetylserine sulfhydrylase is the anchor point for bienzyme complex formation with serine acetyltransferase. J Bacteriol (2005) 1.02

Inhibition of the Myotoxicity Induced by Bothrops jararacussu Venom and Isolated Phospholipases A2 by Specific Camelid Single-Domain Antibody Fragments. PLoS One (2016) 1.02

Peptide- and proton-driven allosteric clamps catalyze anthrax toxin translocation across membranes. Proc Natl Acad Sci U S A (2016) 1.02

Contribution of the intrinsic mechanical energy of the phosphodiester linkage to the relative stability of the A, BI, and BII forms of duplex DNA. J Phys Chem B (2009) 1.01

Steric restrictions in protein folding: an alpha-helix cannot be followed by a contiguous beta-strand. Protein Sci (2004) 1.01

Crystal structures of the glutamate receptor ion channel GluK3 and GluK5 amino-terminal domains. J Mol Biol (2010) 1.01

Assessing side-chain perturbations of the protein backbone: a knowledge-based classification of residue Ramachandran space. J Mol Biol (2008) 1.00

Unblocked statistical-coil tetrapeptides and pentapeptides in aqueous solution: a theoretical study. J Biomol NMR (2002) 1.00

Structure of the ternary complex of phosphomevalonate kinase: the enzyme and its family. Biochemistry (2009) 1.00

Secondary structure determines protein topology. Protein Sci (2006) 1.00

Defining and searching for structural motifs using DeepView/Swiss-PdbViewer. BMC Bioinformatics (2012) 1.00

Revisiting the Ramachandran plot from a new angle. Protein Sci (2011) 1.00

Functional characterizations of chemosensory proteins of the alfalfa plant bug Adelphocoris lineolatus indicate their involvement in host recognition. PLoS One (2012) 1.00

Structure of collagen. Nature (1955) 2.45

Structure of collagen. Nature (1954) 1.62

Structure of collagen. Nature (1956) 1.20

Cylindrical lattice structure of collagen. Arch Biochem Biophys (1956) 0.94

Structure of collagen. Nature (1961) 0.87

In vitro calcification of collagen. Experientia (1956) 0.82

MOLECULAR STRUCTURE OF COLLAGEN. Int Rev Connect Tissue Res (1963) 0.76

Photoelastic constants of sodium chlorate. Nature (1951) 0.75

The structure of chitin. Biochim Biophys Acta (1962) 0.75

Oriented crystallization of inorganic salts in collagen. Experientia (1955) 0.75

Determination of elastic constants from diffuse reflexion of X-rays. Nature (1949) 0.75