Published in Biochim Biophys Acta on April 22, 1960
Genetic aspects of bacterial endospore formation. Bacteriol Rev (1976) 11.55
Transformation studies on the linkage of markers in the tryptophan pathway in Bacillus subtilis. Proc Natl Acad Sci U S A (1961) 9.73
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Integration efficiency and genetic recombination in pneumococcal transformation. Genetics (1966) 6.67
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The mapping of genetic loci affecting streptomycin resistance in Pneumococcus. Genetics (1961) 2.62
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Biofilm formation by Streptococcus pneumoniae: role of choline, extracellular DNA, and capsular polysaccharide in microbial accretion. J Bacteriol (2006) 2.42
Microarray analysis of pneumococcal gene expression during invasive disease. Infect Immun (2004) 2.38
Identification of a Candidate Streptococcus pneumoniae core genome and regions of diversity correlated with invasive pneumococcal disease. Infect Immun (2006) 2.33
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In vivo interaction of beta-lactam antibiotics with the penicillin-binding proteins of Streptococcus pneumoniae. Antimicrob Agents Chemother (1980) 2.29
Fine-structure mapping by transformation in the tryptophan region of Bacillus subtilis. J Bacteriol (1966) 2.27
Integration and Expression of Different Lengths of DNA during the Transformation of Pneumococcus to Erythromycin Resistance. Genetics (1962) 2.23
Factors contributing to hydrogen peroxide resistance in Streptococcus pneumoniae include pyruvate oxidase (SpxB) and avoidance of the toxic effects of the fenton reaction. J Bacteriol (2003) 2.20
Relationship between cell surface carbohydrates and intrastrain variation on opsonophagocytosis of Streptococcus pneumoniae. Infect Immun (1999) 2.20
Insertional inactivation of the major autolysin gene of Streptococcus pneumoniae. J Bacteriol (1988) 2.18
Acquisition of five high-Mr penicillin-binding protein variants during transfer of high-level beta-lactam resistance from Streptococcus mitis to Streptococcus pneumoniae. J Bacteriol (1998) 2.16
Nucleotide sequences of genes encoding penicillin-binding proteins from Streptococcus pneumoniae and Streptococcus oralis with high homology to Escherichia coli penicillin-binding proteins 1a and 1b. J Bacteriol (1992) 2.11
Selective heat inactivation of pneumococcal transforming deoxyribonucleate. Proc Natl Acad Sci U S A (1961) 2.11
Intergenotic transformation of the Bacillus subtilis genospecies. J Bacteriol (1972) 2.07
Relatedness of penicillin-binding protein 1a genes from different clones of penicillin-resistant Streptococcus pneumoniae isolated in South Africa and Spain. EMBO J (1992) 2.06
Peptide methionine sulfoxide reductase contributes to the maintenance of adhesins in three major pathogens. Proc Natl Acad Sci U S A (1996) 2.05
Role of the manganese efflux system mntE for signalling and pathogenesis in Streptococcus pneumoniae. Mol Microbiol (2009) 2.03
Suppression of the lytic and bactericidal effects of cell wallinhibitory antibiotics. Antimicrob Agents Chemother (1976) 2.02
Statistical estimate of the total number of operons specific for Bacillus subtilis sporulation. J Bacteriol (1974) 2.01
The Streptococcus pneumoniae cia regulon: CiaR target sites and transcription profile analysis. J Bacteriol (2003) 1.99
Identification of multiple clones of extended-spectrum cephalosporin-resistant Streptococcus pneumoniae isolates in the United States. Antimicrob Agents Chemother (1995) 1.96
The genetics of alkaline phosphatase formation in Bacillus subtilis. Genetics (1965) 1.96
Genetic evidence that Neisseria gonorrhoeae produces specific receptors for transferrin and lactoferrin. J Bacteriol (1990) 1.94
The Streptococcus pneumoniae beta-galactosidase is a surface protein. J Bacteriol (2000) 1.89
Relative frequencies of different kinds of spontaneous and induced mutants of pneumococci and streptococci capable of growth in the presence of streptomycin. J Bacteriol (1965) 1.88
Microarray-based identification of htrA, a Streptococcus pneumoniae gene that is regulated by the CiaRH two-component system and contributes to nasopharyngeal colonization. Infect Immun (2002) 1.87
Relationship between phase variation in colony morphology, intrastrain variation in cell wall physiology, and nasopharyngeal colonization by Streptococcus pneumoniae. Infect Immun (1996) 1.85
Growth of Streptococcus pneumoniae on human glycoconjugates is dependent upon the sequential activity of bacterial exoglycosidases. J Bacteriol (2007) 1.82
ParC and GyrA may be interchangeable initial targets of some fluoroquinolones in Streptococcus pneumoniae. Antimicrob Agents Chemother (1999) 1.81
Antibody-enhanced pneumococcal adherence requires IgA1 protease. Proc Natl Acad Sci U S A (2003) 1.81
Two bactericidal targets for penicillin in pneumococci: autolysis-dependent and autolysis-independent killing mechanisms. Antimicrob Agents Chemother (1990) 1.80
Lysogenic pneumococci and their bacteriophages. J Bacteriol (1979) 1.78
Respiratory viruses augment the adhesion of bacterial pathogens to respiratory epithelium in a viral species- and cell type-dependent manner. J Virol (2006) 1.78
Alterations in kinetic properties of penicillin-binding proteins of penicillin-resistant Streptococcus pneumoniae. Antimicrob Agents Chemother (1986) 1.76
The blp bacteriocins of Streptococcus pneumoniae mediate intraspecies competition both in vitro and in vivo. Infect Immun (2006) 1.75
Loss of activity of transforming deoxyribonucleic acid after uptake by Haemophilus influenzae. J Bacteriol (1965) 1.71
A functional dlt operon, encoding proteins required for incorporation of d-alanine in teichoic acids in gram-positive bacteria, confers resistance to cationic antimicrobial peptides in Streptococcus pneumoniae. J Bacteriol (2006) 1.69
Purification and polar localization of pneumococcal LytB, a putative endo-beta-N-acetylglucosaminidase: the chain-dispersing murein hydrolase. J Bacteriol (2002) 1.66
Genetic diversity and clonal patterns among antibiotic-susceptible and -resistant Streptococcus pneumoniae colonizing children: day care centers as autonomous epidemiological units. J Clin Microbiol (2000) 1.64
Genetic studies relating to the production of transformed clones diploid in the tryptophan region of the Bacillus subtilis genome. J Bacteriol (1973) 1.64
Emergence of hypervirulent mutants resistant to early clearance during systemic serotype 1 pneumococcal infection in mice and humans. J Infect Dis (2014) 1.62
Release of lipoteichoic acid from Streptococcus sanguis: stimulation of release during penicillin treatment. J Bacteriol (1979) 1.61
beta-Arrestin 1 participates in platelet-activating factor receptor-mediated endocytosis of Streptococcus pneumoniae. Infect Immun (2005) 1.60
Pneumolysin, a protein toxin of Streptococcus pneumoniae, induces nitric oxide production from macrophages. Infect Immun (1999) 1.60
Identification, cloning, and sequencing of the immunoglobulin A1 protease gene of Streptococcus pneumoniae. Infect Immun (1996) 1.60
Molecular characterization of the complete 23F capsular polysaccharide locus of Streptococcus pneumoniae. J Bacteriol (1998) 1.55
Hydroxyurea therapy of a murine model of sickle cell anemia inhibits the progression of pneumococcal disease by down-modulating E-selectin. Blood (2011) 1.54
Selection of cells transformed to prototrophy for sporulation markers. J Bacteriol (1971) 1.50
Isolation of mutants defective in alpha-amylase from Bacillus subtilis: genetic analyses. J Bacteriol (1974) 1.49
Solution structure of choline binding protein A, the major adhesin of Streptococcus pneumoniae. EMBO J (2004) 1.47
Unusual septum formation in Streptococcus pneumoniae mutants with an alteration in the D,D-carboxypeptidase penicillin-binding protein 3. J Bacteriol (1990) 1.47
Control of virulence by small RNAs in Streptococcus pneumoniae. PLoS Pathog (2012) 1.46
Statins protect against fulminant pneumococcal infection and cytolysin toxicity in a mouse model of sickle cell disease. J Clin Invest (2010) 1.44
Altered peptidoglycan structure in a pneumococcal transformant resistant to penicillin. J Bacteriol (1988) 1.44
Aromatic amino acid biosynthesis: gene-enzyme relationships in Bacillus subtilis. J Bacteriol (1967) 1.44
Pneumococcal genome sequencing tracks a vaccine escape variant formed through a multi-fragment recombination event. Nat Genet (2012) 1.43
Increased dihydrofolate reductase synthess in Diplococcus pneumoniae following translatable alteration of the structural gene. I. Genotype derivation and recombinational analyses. Genetics (1969) 1.43
Menaquinone biosynthesis in Bacillus subtilis: isolation of men mutants and evidence for clustering of men genes. J Bacteriol (1981) 1.40
Identification of a Streptococcus pneumoniae gene locus encoding proteins of an ABC phosphate transporter and a two-component regulatory system. J Bacteriol (1999) 1.40
Role of HtrA in the virulence and competence of Streptococcus pneumoniae. Infect Immun (2004) 1.40
Diversity of bacteriocins and activity spectrum in Streptococcus pneumoniae. J Bacteriol (2007) 1.38
Regulation of the alpha-galactosidase activity in Streptococcus pneumoniae: characterization of the raffinose utilization system. Genome Res (1999) 1.35
Characterization of the galU gene of Streptococcus pneumoniae encoding a uridine diphosphoglucose pyrophosphorylase: a gene essential for capsular polysaccharide biosynthesis. J Exp Med (1998) 1.35
Molecular peculiarities of the lytA gene isolated from clinical pneumococcal strains that are bile insoluble. J Clin Microbiol (2002) 1.34
Genetic and biochemical properties of thymidine-dependent mutants of pneumococcus. J Bacteriol (1972) 1.34
Mutational analysis of the Streptococcus pneumoniae bimodular class A penicillin-binding proteins. J Bacteriol (1999) 1.33
ON THE ROLE OF INTEGRITY OF DNA PARTICLES IN GENETIC RECOMBINATION DURING PNEUMOCOCCAL TRANSFORMATION. Proc Natl Acad Sci U S A (1963) 1.33
A high incidence of prophage carriage among natural isolates of Streptococcus pneumoniae. J Bacteriol (1999) 1.33
Calcium efflux is essential for bacterial survival in the eukaryotic host. Mol Microbiol (2008) 1.33
Central role of manganese in regulation of stress responses, physiology, and metabolism in Streptococcus pneumoniae. J Bacteriol (2010) 1.32
Possible role of a choline-containing teichoic acid in the maintenance of normal cell shape and physiology in Streptococcus oralis. J Bacteriol (1993) 1.30
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Fate of transforming deoxyribonucleate following fixation by transformable bacteria. Nature (1960) 5.15
Analysis of the complex sulfonamide resistance locus of pneumococcus. Cold Spring Harb Symp Quant Biol (1958) 5.04
Release of genetic transforming agent from pneumococcal cultures during growth and disintegration. J Exp Med (1962) 4.45
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Mannitol metabolism, a transferable property of pneumococcus. J Biol Chem (1955) 2.41
Appearance of genetic transforming activity in pneumococcal cultures. Science (1960) 2.26
Formation of amylomaltase after genetic transformation of pneumococcus. Biochim Biophys Acta (1960) 2.17
Selective heat inactivation of pneumococcal transforming deoxyribonucleate. Proc Natl Acad Sci U S A (1961) 2.11
The genetic chemistry of the pneumococcal transformations. Harvey Lect (1955) 1.77
The assimilation of amino acids by respiring washed Staphylococci. Arch Biochem Biophys (1956) 1.58
Size limitations governing the incorporation of genetic material in the bacterial transformations and other non-reciprocal recombinations. Symp Soc Exp Biol (1958) 1.58
KINETIC ANALYSIS OF MULTIPLE, LINKED RECOMBINATIONS IN PNEUMOCOCCAL TRANSFORMATION. J Mol Biol (1964) 1.47
Fine structure of a genetically modified enzyme as revealed by relative affinities for modified substrate. Fed Proc (1960) 1.39
ON THE ROLE OF INTEGRITY OF DNA PARTICLES IN GENETIC RECOMBINATION DURING PNEUMOCOCCAL TRANSFORMATION. Proc Natl Acad Sci U S A (1963) 1.33
The quantitative separation of purines, pyrimidines, and nucleosides by paper chromatography. J Biol Chem (1948) 1.28
Genetically modified folic acid synthesizing enzymes of pneumococcus. Biochemistry (1963) 1.24
The mode of action of chemotherapeutic agents. Annu Rev Microbiol (1948) 0.86
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