Published in Cell on September 19, 2003
STIM1, an essential and conserved component of store-operated Ca2+ channel function. J Cell Biol (2005) 13.11
TRP channels. Annu Rev Biochem (2007) 8.09
Inositol trisphosphate receptor Ca2+ release channels. Physiol Rev (2007) 5.95
Large store-operated calcium selective currents due to co-expression of Orai1 or Orai2 with the intracellular calcium sensor, Stim1. J Biol Chem (2006) 5.32
SOAR and the polybasic STIM1 domains gate and regulate Orai channels. Nat Cell Biol (2009) 4.73
Elongation factor 2 and fragile X mental retardation protein control the dynamic translation of Arc/Arg3.1 essential for mGluR-LTD. Neuron (2008) 3.97
STIM1 heteromultimerizes TRPC channels to determine their function as store-operated channels. Nat Cell Biol (2007) 3.47
Dynamic assembly of TRPC1-STIM1-Orai1 ternary complex is involved in store-operated calcium influx. Evidence for similarities in store-operated and calcium release-activated calcium channel components. J Biol Chem (2007) 2.63
Physiology and pathophysiology of canonical transient receptor potential channels. FASEB J (2008) 2.31
STIM1 gates TRPC channels, but not Orai1, by electrostatic interaction. Mol Cell (2008) 2.30
The postsynaptic density proteins Homer and Shank form a polymeric network structure. Cell (2009) 2.27
Pressure-induced and store-operated cation influx in vascular smooth muscle cells is independent of TRPC1. Pflugers Arch (2007) 2.17
Non-selective cationic channels of smooth muscle and the mammalian homologues of Drosophila TRP. J Physiol (2004) 2.03
Non-vesicular lipid transport by lipid-transfer proteins and beyond. Nat Rev Mol Cell Biol (2010) 1.84
The Homer family proteins. Genome Biol (2007) 1.78
Regulation of GPCR activity, trafficking and localization by GPCR-interacting proteins. Br J Pharmacol (2012) 1.69
Human TRPC5 channel activated by a multiplicity of signals in a single cell. J Physiol (2004) 1.63
Multiple functions of endocannabinoid signaling in the brain. Annu Rev Neurosci (2012) 1.60
Homeostatic scaling requires group I mGluR activation mediated by Homer1a. Neuron (2010) 1.59
The function of activity-regulated genes in the nervous system. Physiol Rev (2009) 1.54
Visualization of localized store-operated calcium entry in mouse astrocytes. Close proximity to the endoplasmic reticulum. J Physiol (2005) 1.50
TRPC1: store-operated channel and more. Pflugers Arch (2005) 1.47
Homer proteins in Ca2+ signaling by excitable and non-excitable cells. Cell Calcium (2007) 1.45
Homers regulate drug-induced neuroplasticity: implications for addiction. Biochem Pharmacol (2007) 1.43
The diacylgylcerol-sensitive TRPC3/6/7 subfamily of cation channels: functional characterization and physiological relevance. Pflugers Arch (2005) 1.40
Conformation of ryanodine receptor-2 gates store-operated calcium entry in rat pulmonary arterial myocytes. Cardiovasc Res (2016) 1.39
TRPC1 and TRPC6 channels cooperate with TRPV4 to mediate mechanical hyperalgesia and nociceptor sensitization. J Neurosci (2009) 1.38
TRP channels and Ca2+ signaling. Cell Calcium (2006) 1.35
Native Store-operated Ca2+ Influx Requires the Channel Function of Orai1 and TRPC1. J Biol Chem (2009) 1.34
Food-associated cues alter forebrain functional connectivity as assessed with immediate early gene and proenkephalin expression. BMC Biol (2007) 1.31
TRP channels in hypertension. Biochim Biophys Acta (2007) 1.25
Regulation of Ca2+ signaling with particular focus on mast cells. Crit Rev Immunol (2009) 1.20
Homer 1a uncouples metabotropic glutamate receptor 5 from postsynaptic effectors. Proc Natl Acad Sci U S A (2007) 1.19
Identification of ML204, a novel potent antagonist that selectively modulates native TRPC4/C5 ion channels. J Biol Chem (2011) 1.16
Functional characterization and physiological relevance of the TRPC3/6/7 subfamily of cation channels. Naunyn Schmiedebergs Arch Pharmacol (2005) 1.15
Functional role of TRPC channels in the regulation of endothelial permeability. Pflugers Arch (2005) 1.13
Preso1 dynamically regulates group I metabotropic glutamate receptors. Nat Neurosci (2012) 1.12
Mice lacking Homer 1 exhibit a skeletal myopathy characterized by abnormal transient receptor potential channel activity. Mol Cell Biol (2008) 1.12
The Na-K-ATPase and calcium-signaling microdomains. Physiology (Bethesda) (2008) 1.11
Insights on TRP channels from in vivo studies in Drosophila. Annu Rev Physiol (2006) 1.09
Klotho is associated with VEGF receptor-2 and the transient receptor potential canonical-1 Ca2+ channel to maintain endothelial integrity. Proc Natl Acad Sci U S A (2010) 1.08
Surface clustering of metabotropic glutamate receptor 1 induced by long Homer proteins. BMC Neurosci (2006) 1.06
The Homer-1 protein Ania-3 interacts with the plasma membrane calcium pump. Biochem Biophys Res Commun (2006) 1.05
Transient receptor potential channels as novel effectors of brain-derived neurotrophic factor signaling: potential implications for Rett syndrome. Pharmacol Ther (2006) 1.03
Lipid rafts establish calcium waves in hepatocytes. Gastroenterology (2007) 1.01
Interaction of Cupidin/Homer2 with two actin cytoskeletal regulators, Cdc42 small GTPase and Drebrin, in dendritic spines. BMC Neurosci (2009) 1.01
Organization and function of TRPC channelosomes. Pflugers Arch (2007) 1.01
Chemico-genetic identification of drebrin as a regulator of calcium responses. Int J Biochem Cell Biol (2009) 0.99
Requirement of the immediate early gene vesl-1S/homer-1a for fear memory formation. Mol Brain (2009) 0.99
Regulation of motor performance and striatal function by synaptic scaffolding proteins of the Homer1 family. Proc Natl Acad Sci U S A (2006) 0.99
The closing and opening of TRPC channels by Homer1 and STIM1. Acta Physiol (Oxf) (2011) 0.99
Rescue of synaptic plasticity and spatial learning deficits in the hippocampus of Homer1 knockout mice by recombinant Adeno-associated viral gene delivery of Homer1c. Neurobiol Learn Mem (2011) 0.97
Protein-protein interaction and functionTRPC channels. Pflugers Arch (2005) 0.97
The history of TRP channels, a commentary and reflection. Pflugers Arch (2011) 0.96
Polycystin-1 interacts with inositol 1,4,5-trisphosphate receptor to modulate intracellular Ca2+ signaling with implications for polycystic kidney disease. J Biol Chem (2009) 0.96
The role of store-operated calcium influx in skeletal muscle signaling. Cell Calcium (2010) 0.96
Peptidyl-prolyl isomerase FKBP52 controls chemotropic guidance of neuronal growth cones via regulation of TRPC1 channel opening. Neuron (2009) 0.96
Diversity of polyproline recognition by EVH1 domains. Front Biosci (Landmark Ed) (2009) 0.95
TRPC3 regulates agonist-stimulated Ca2+ mobilization by mediating the interaction between type I inositol 1,4,5-trisphosphate receptor, RACK1, and Orai1. J Biol Chem (2009) 0.95
Regulation of TRPC1 and TRPC4 cation channels requires an alpha1-syntrophin-dependent complex in skeletal mouse myotubes. J Biol Chem (2009) 0.95
Dysregulation of group-I metabotropic glutamate (mGlu) receptor mediated signalling in disorders associated with Intellectual Disability and Autism. Neurosci Biobehav Rev (2014) 0.94
Functional roles of TRPC channels in the developing brain. Pflugers Arch (2008) 0.93
PIKE GTPase are phosphoinositide-3-kinase enhancers, suppressing programmed cell death. J Cell Mol Med (2007) 0.93
Caspase-11 controls interleukin-1β release through degradation of TRPC1. Cell Rep (2014) 0.93
The TR (i)P to Ca²⁺ signaling just got STIMy: an update on STIM1 activated TRPC channels. Front Biosci (Landmark Ed) (2012) 0.91
Alcohol impairs long-term depression at the cerebellar parallel fiber-Purkinje cell synapse. J Neurophysiol (2008) 0.91
The cellular building blocks of breathing. Compr Physiol (2012) 0.91
Homer and the ryanodine receptor. Eur Biophys J (2009) 0.91
Protein Kinase C Epsilon Activity in the Nucleus Accumbens and Central Nucleus of the Amygdala Mediates Binge Alcohol Consumption. Biol Psychiatry (2015) 0.91
Dynamic regulation of ryanodine receptor type 1 (RyR1) channel activity by Homer 1. Cell Calcium (2007) 0.90
Polycystin-1, 2, and STIM1 interact with IP(3)R to modulate ER Ca release through the PI3K/Akt pathway. Cell Physiol Biochem (2011) 0.90
TRP Channels as Sensors and Signal Integrators of Redox Status Changes. Front Pharmacol (2011) 0.88
The dynamic complexity of the TRPC1 channelosome. Channels (Austin) (2011) 0.88
Mechanism and functional significance of TRPC channel multimerization. Semin Cell Dev Biol (2006) 0.87
Fragile X Syndrome and Alzheimer's Disease: Another story about APP and beta-amyloid. Curr Alzheimer Res (2010) 0.87
Homer regulates calcium signalling in growth cone turning. Neural Dev (2009) 0.87
Cocaine activates Homer1 immediate early gene transcription in the mesocorticolimbic circuit: differential regulation by dopamine and glutamate signaling. Synapse (2009) 0.86
Role of exercise in maintaining the integrity of the neuromuscular junction. Muscle Nerve (2013) 0.86
Enrichment of conserved synaptic activity-responsive element in neuronal genes predicts a coordinated response of MEF2, CREB and SRF. PLoS One (2013) 0.85
Interaction with dopamine D2 receptor enhances expression of transient receptor potential channel 1 at the cell surface. Biochim Biophys Acta (2008) 0.85
mGluR1/TRPC3-mediated Synaptic Transmission and Calcium Signaling in Mammalian Central Neurons. Cold Spring Harb Perspect Biol (2011) 0.85
Absence of Dystrophin Disrupts Skeletal Muscle Signaling: Roles of Ca2+, Reactive Oxygen Species, and Nitric Oxide in the Development of Muscular Dystrophy. Physiol Rev (2016) 0.85
The TRPC2 channel forms protein-protein interactions with Homer and RTP in the rat vomeronasal organ. BMC Neurosci (2010) 0.84
A novel postsynaptic mechanism for heterosynaptic sharing of short-term plasticity. J Neurosci (2010) 0.84
Distinct mechanisms regulating mechanical force-induced Ca²⁺ signals at the plasma membrane and the ER in human MSCs. Elife (2015) 0.84
The role of Homer1c in metabotropic glutamate receptor-dependent long-term potentiation. Hippocampus (2013) 0.84
An intelligent nano-antenna: Primary cilium harnesses TRP channels to decode polymodal stimuli. Cell Calcium (2015) 0.83
Cellular functions of transient receptor potential channels. Int J Biochem Cell Biol (2010) 0.83
Isoform- and receptor-specific channel property of canonical transient receptor potential (TRPC)1/4 channels. Pflugers Arch (2013) 0.83
Classical Transient Receptor Potential 1 (TRPC1): Channel or Channel Regulator? Cells (2014) 0.82
Functional coupling of the metabotropic glutamate receptor, InsP3 receptor and L-type Ca2+ channel in mouse CA1 pyramidal cells. J Physiol (2012) 0.82
Junctional membrane inositol 1,4,5-trisphosphate receptor complex coordinates sensitization of the silent EGF-induced Ca2+ signaling. J Cell Biol (2005) 0.82
Protective effects of SKF-96365, a non-specific inhibitor of SOCE, against MPP+-induced cytotoxicity in PC12 cells: potential role of Homer1. PLoS One (2013) 0.82
Vomeronasal sensory neurons from Sternotherus odoratus (stinkpot/musk turtle) respond to chemosignals via the phospholipase C system. J Exp Biol (2006) 0.81
Homer proteins shape Xenopus optic tectal cell dendritic arbor development in vivo. Dev Neurobiol (2008) 0.81
The type I inositol 1,4,5-trisphosphate receptor interacts with protein 4.1N to mediate neurite formation through intracellular Ca waves. Neurosignals (2011) 0.81
Severely blunted allergen-induced pulmonary Th2 cell response and lung hyperresponsiveness in type 1 transient receptor potential channel-deficient mice. Am J Physiol Lung Cell Mol Physiol (2012) 0.81
Inositol 1,4,5-trisphosphate receptors and their protein partners as signalling hubs. J Physiol (2016) 0.81
TRP channels and STIM/ORAI proteins: sensors and effectors of cancer and stroma cell migration. Br J Pharmacol (2014) 0.80
Homer1a attenuates glutamate-induced oxidative injury in HT-22 cells through regulation of store-operated calcium entry. Sci Rep (2016) 0.79
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy (2007) 20.92
Widespread transcription at neuronal activity-regulated enhancers. Nature (2010) 16.52
Modulation of microRNA processing and expression through RNA editing by ADAR deaminases. Nat Struct Mol Biol (2005) 7.49
The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment. Immunity (2009) 6.86
STIM1 carboxyl-terminus activates native SOC, I(crac) and TRPC1 channels. Nat Cell Biol (2006) 5.68
Arc/Arg3.1 mediates homeostatic synaptic scaling of AMPA receptors. Neuron (2006) 5.48
The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2. Nat Immunol (2011) 5.22
A protocol for rapid generation of recombinant adenoviruses using the AdEasy system. Nat Protoc (2007) 5.15
Arc/Arg3.1 interacts with the endocytic machinery to regulate AMPA receptor trafficking. Neuron (2006) 4.98
SOAR and the polybasic STIM1 domains gate and regulate Orai channels. Nat Cell Biol (2009) 4.73
The Angelman Syndrome protein Ube3A regulates synapse development by ubiquitinating arc. Cell (2010) 4.72
Blockade of TGF-beta inhibits mammary tumor cell viability, migration, and metastases. J Clin Invest (2002) 4.64
Subunit composition of synaptic AMPA receptors revealed by a single-cell genetic approach. Neuron (2009) 4.18
Elongation factor 2 and fragile X mental retardation protein control the dynamic translation of Arc/Arg3.1 essential for mGluR-LTD. Neuron (2008) 3.97
Liver disintegration in the mouse embryo caused by deficiency in the RNA-editing enzyme ADAR1. J Biol Chem (2003) 3.68
Evoked axonal oxytocin release in the central amygdala attenuates fear response. Neuron (2012) 3.57
STIM1 heteromultimerizes TRPC channels to determine their function as store-operated channels. Nat Cell Biol (2007) 3.47
Gating of CFTR by the STAS domain of SLC26 transporters. Nat Cell Biol (2004) 3.43
Pathogenomic sequence analysis of Bacillus cereus and Bacillus thuringiensis isolates closely related to Bacillus anthracis. J Bacteriol (2006) 3.23
CKAMP44: a brain-specific protein attenuating short-term synaptic plasticity in the dentate gyrus. Science (2010) 3.17
Shank expression is sufficient to induce functional dendritic spine synapses in aspiny neurons. J Neurosci (2005) 2.96
Common variants associated with plasma triglycerides and risk for coronary artery disease. Nat Genet (2013) 2.92
Mutant huntingtin binds the mitochondrial fission GTPase dynamin-related protein-1 and increases its enzymatic activity. Nat Med (2011) 2.87
Induction therapy with autologous mesenchymal stem cells in living-related kidney transplants: a randomized controlled trial. JAMA (2012) 2.85
Increased expression of the immediate-early gene arc/arg3.1 reduces AMPA receptor-mediated synaptic transmission. Neuron (2006) 2.79
Podocyte-selective deletion of dicer induces proteinuria and glomerulosclerosis. J Am Soc Nephrol (2008) 2.74
The immediate early gene arc/arg3.1: regulation, mechanisms, and function. J Neurosci (2008) 2.73
Spatial exploration-induced Arc mRNA and protein expression: evidence for selective, network-specific reactivation. J Neurosci (2005) 2.69
Pancreatic islet production of vascular endothelial growth factor--a is essential for islet vascularization, revascularization, and function. Diabetes (2006) 2.53
Soluble Eph A receptors inhibit tumor angiogenesis and progression in vivo. Oncogene (2002) 2.41
Synaptic inhibition in the olfactory bulb accelerates odor discrimination in mice. Neuron (2010) 2.40
Activation of the TRPC1 cation channel by metabotropic glutamate receptor mGluR1. Nature (2003) 2.31
STIM1 gates TRPC channels, but not Orai1, by electrostatic interaction. Mol Cell (2008) 2.30
Stereotaxic gene delivery in the rodent brain. Nat Protoc (2006) 2.27
The AMPA receptor subunits GluR-A and GluR-B reciprocally modulate spinal synaptic plasticity and inflammatory pain. Neuron (2004) 2.26
Lack of NMDA receptor subtype selectivity for hippocampal long-term potentiation. J Neurosci (2005) 2.19
Integration of new neurons into functional neural networks. J Neurosci (2006) 2.18
Homer2 is necessary for EtOH-induced neuroplasticity. J Neurosci (2005) 2.17
Mapping behaviorally relevant neural circuits with immediate-early gene expression. Curr Opin Neurobiol (2005) 2.16
Inverse synaptic tagging of inactive synapses via dynamic interaction of Arc/Arg3.1 with CaMKIIβ. Cell (2012) 2.14
Synaptic activity-responsive element in the Arc/Arg3.1 promoter essential for synapse-to-nucleus signaling in activated neurons. Proc Natl Acad Sci U S A (2008) 2.13
A molecular mechanism for aberrant CFTR-dependent HCO(3)(-) transport in cystic fibrosis. EMBO J (2002) 2.11
The receptor tyrosine kinase EphA2 promotes mammary adenocarcinoma tumorigenesis and metastatic progression in mice by amplifying ErbB2 signaling. J Clin Invest (2008) 2.11
Photon capture and signalling by melanopsin retinal ganglion cells. Nature (2008) 2.08
PI3 kinase enhancer-Homer complex couples mGluRI to PI3 kinase, preventing neuronal apoptosis. Nat Neurosci (2003) 2.06
TRPC channels as STIM1-regulated store-operated channels. Cell Calcium (2007) 2.04
NaBC1 is a ubiquitous electrogenic Na+ -coupled borate transporter essential for cellular boron homeostasis and cell growth and proliferation. Mol Cell (2004) 2.02
Oligodendrocyte progenitors balance growth with self-repulsion to achieve homeostasis in the adult brain. Nat Neurosci (2013) 1.98
Blockade of EphA receptor tyrosine kinase activation inhibits vascular endothelial cell growth factor-induced angiogenesis. Mol Cancer Res (2002) 1.96
TRP-ML1 regulates lysosomal pH and acidic lysosomal lipid hydrolytic activity. J Biol Chem (2005) 1.96
Induced loss of ADAR2 engenders slow death of motor neurons from Q/R site-unedited GluR2. J Neurosci (2010) 1.91
Transporter-mediated bile acid uptake causes Ca2+-dependent cell death in rat pancreatic acinar cells. Gastroenterology (2002) 1.91
Spatial exploration induces ARC, a plasticity-related immediate-early gene, only in calcium/calmodulin-dependent protein kinase II-positive principal excitatory and inhibitory neurons of the rat forebrain. J Comp Neurol (2006) 1.90
Acetylation modulates cellular distribution and DNA sensing ability of interferon-inducible protein IFI16. Proc Natl Acad Sci U S A (2012) 1.88
Regulation of osteogenic differentiation during skeletal development. Front Biosci (2008) 1.88
Experience-dependent coincident expression of the effector immediate-early genes arc and Homer 1a in hippocampal and neocortical neuronal networks. J Neurosci (2002) 1.88
A comprehensive analysis of the dual roles of BMPs in regulating adipogenic and osteogenic differentiation of mesenchymal progenitor cells. Stem Cells Dev (2009) 1.87
Corticosteroids correct aberrant CFTR localization in the duct and regenerate acinar cells in autoimmune pancreatitis. Gastroenterology (2010) 1.86
Recent behavioral history modifies coupling between cell activity and Arc gene transcription in hippocampal CA1 neurons. Proc Natl Acad Sci U S A (2006) 1.85
Seed size, more than nutrient or tannin content, affects seed caching behavior of a common genus of Old World rodents. Ecology (2009) 1.85
Homer proteins regulate sensitivity to cocaine. Neuron (2004) 1.83
Reduced cortical inhibition in a mouse model of familial childhood absence epilepsy. Proc Natl Acad Sci U S A (2007) 1.82
EphA2 receptor tyrosine kinase regulates endothelial cell migration and vascular assembly through phosphoinositide 3-kinase-mediated Rac1 GTPase activation. J Cell Sci (2004) 1.82
The ephrins and Eph receptors in angiogenesis. Cytokine Growth Factor Rev (2002) 1.80
Sindbis vector SINrep(nsP2S726): a tool for rapid heterologous expression with attenuated cytotoxicity in neurons. J Neurosci Methods (2004) 1.79
Contribution of hippocampal and extra-hippocampal NR2B-containing NMDA receptors to performance on spatial learning tasks. Neuron (2008) 1.78
Comprehensive proteomic profiling of the membrane constituents of a Mycobacterium tuberculosis strain. Mol Cell Proteomics (2003) 1.77
Recent advances in tumor-targeting anticancer drug conjugates. Bioorg Med Chem (2005) 1.77
Inhibition of dendritic spine morphogenesis and synaptic transmission by activity-inducible protein Homer1a. J Neurosci (2003) 1.77
The solute carrier 26 family of proteins in epithelial ion transport. Physiology (Bethesda) (2008) 1.76
TRP-ML1 is a lysosomal monovalent cation channel that undergoes proteolytic cleavage. J Biol Chem (2005) 1.75
Coupling modes and stoichiometry of Cl-/HCO3- exchange by slc26a3 and slc26a6. J Gen Physiol (2006) 1.73
Mycobacterium tuberculosis functional network analysis by global subcellular protein profiling. Mol Biol Cell (2004) 1.73
The ephrin receptor tyrosine kinase A2 is a cellular receptor for Kaposi's sarcoma–associated herpesvirus. Nat Med (2012) 1.72
Protease-activated receptor 2 exerts local protection and mediates some systemic complications in acute pancreatitis. Gastroenterology (2004) 1.72
Molecular mechanism of pancreatic and salivary gland fluid and HCO3 secretion. Physiol Rev (2012) 1.71
Hedgehog agonist therapy corrects structural and cognitive deficits in a Down syndrome mouse model. Sci Transl Med (2013) 1.70
Hypoxia reprograms calcium signaling and regulates myoglobin expression. Am J Physiol Cell Physiol (2008) 1.69
Neuroinflammation alters the hippocampal pattern of behaviorally induced Arc expression. J Neurosci (2005) 1.64
Molecular and cellular approaches for the detection of protein-protein interactions: latest techniques and current limitations. Plant J (2008) 1.62
Hippocampal NMDA receptors and anxiety: at the interface between cognition and emotion. Eur J Pharmacol (2009) 1.62
Retracted Enhanced polyubiquitination of Shank3 and NMDA receptor in a mouse model of autism. Cell (2011) 1.62
Monte Carlo based method for fluorescence tomographic imaging with lifetime multiplexing using time gates. Biomed Opt Express (2011) 1.61
Mitochondrial aberrations in mucolipidosis Type IV. J Biol Chem (2006) 1.61
hnRNP C promotes APP translation by competing with FMRP for APP mRNA recruitment to P bodies. Nat Struct Mol Biol (2010) 1.61
Impaired tumor microenvironment in EphA2-deficient mice inhibits tumor angiogenesis and metastatic progression. FASEB J (2005) 1.61