Published in Blood on October 02, 2003
Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest (2003) 41.22
Functional overlap but differential expression of CSF-1 and IL-34 in their CSF-1 receptor-mediated regulation of myeloid cells. J Leukoc Biol (2010) 2.71
Colony stimulating factor-1 dependence of paneth cell development in the mouse small intestine. Gastroenterology (2009) 1.82
Colony-stimulating factor-1 transfection of myoblasts improves the repair of failing myocardium following autologous myoblast transplantation. Cardiovasc Res (2008) 1.54
IL-34 mediates acute kidney injury and worsens subsequent chronic kidney disease. J Clin Invest (2015) 1.51
The CSF-1 receptor ligands IL-34 and CSF-1 exhibit distinct developmental brain expression patterns and regulate neural progenitor cell maintenance and maturation. Dev Biol (2012) 1.50
CSF-1 receptor structure/function in MacCsf1r-/- macrophages: regulation of proliferation, differentiation, and morphology. J Leukoc Biol (2008) 1.19
Regulation of macrophage development and function in peripheral tissues. Nat Rev Immunol (2015) 1.16
Signaling pathways involved in MDSC regulation. Biochim Biophys Acta (2014) 1.12
CSF-1 receptor signaling in myeloid cells. Cold Spring Harb Perspect Biol (2014) 1.10
T-cell protein tyrosine phosphatase (Tcptp) is a negative regulator of colony-stimulating factor 1 signaling and macrophage differentiation. Mol Cell Biol (2006) 1.02
Myeloid colony-stimulating factors as regulators of macrophage polarization. Front Immunol (2014) 1.00
Developmental and functional significance of the CSF-1 proteoglycan chondroitin sulfate chain. Blood (2005) 0.96
Meox2Cre-mediated disruption of CSF-1 leads to osteopetrosis and osteocyte defects. Bone (2011) 0.94
M-CSF potently augments RANKL-induced resorption activation in mature human osteoclasts. PLoS One (2011) 0.94
Interkeukin-34, a cytokine crucial for the differentiation and maintenance of tissue resident macrophages and Langerhans cells. Eur J Immunol (2014) 0.92
Colony-stimulating factor-1 mediates macrophage-related neural damage in a model for Charcot-Marie-Tooth disease type 1X. Brain (2011) 0.90
Distinct roles of CSF-1 isoforms in lupus nephritis. J Am Soc Nephrol (2011) 0.89
Dendritic cell-mediated in vivo bone resorption. J Immunol (2010) 0.87
Both cell-surface and secreted CSF-1 expressed by tumor cells metastatic to bone can contribute to osteoclast activation. Exp Cell Res (2009) 0.82
Pleiotropic effects of extended blockade of CSF1R signaling in adult mice. J Leukoc Biol (2014) 0.82
Ectodomain shedding of FLT3 ligand is mediated by TNF-alpha converting enzyme. J Immunol (2009) 0.82
Targeted expression of csCSF-1 in op/op mice ameliorates tooth defects. Arch Oral Biol (2006) 0.81
CSF1 Overexpression Promotes High-Grade Glioma Formation without Impacting the Polarization Status of Glioma-Associated Microglia and Macrophages. Cancer Res (2016) 0.78
Donor and recipient cell surface colony stimulating factor-1 promote neointimal formation in transplant-associated arteriosclerosis. Arterioscler Thromb Vasc Biol (2012) 0.78
Biological role of granulocyte macrophage colony-stimulating factor (GM-CSF) and macrophage colony-stimulating factor (M-CSF) on cells of the myeloid lineage. J Leukoc Biol (2016) 0.76
Diverse in vivo effects of soluble and membrane-bound M-CSF on tumor-associated macrophages in lymphoma xenograft model. Oncotarget (2016) 0.76
Cell-Surface and Secreted Isoforms of CSF-1 Exert Opposing Roles in Macrophage-Mediated Neural Damage in Cx32-Deficient Mice. J Neurosci (2016) 0.75
Protein kinase A inhibition of macrophage maturation is accompanied by an increase in DNA methylation of the colony-stimulating factor 1 receptor gene. Immunology (2016) 0.75
Selective deletion of the membrane-bound colony stimulating factor 1 isoform leads to high bone mass but does not protect against estrogen-deficiency bone loss. J Bone Miner Metab (2011) 0.75
Fate mapping analysis reveals that adult microglia derive from primitive macrophages. Science (2010) 12.15
A paracrine loop between tumor cells and macrophages is required for tumor cell migration in mammary tumors. Cancer Res (2004) 7.56
Direct visualization of macrophage-assisted tumor cell intravasation in mammary tumors. Cancer Res (2007) 6.60
Origin of the lamina propria dendritic cell network. Immunity (2009) 5.95
Tissue-resident macrophages self-maintain locally throughout adult life with minimal contribution from circulating monocytes. Immunity (2013) 5.47
Langerhans cells arise from monocytes in vivo. Nat Immunol (2006) 5.46
The origin and development of nonlymphoid tissue CD103+ DCs. J Exp Med (2009) 4.79
Macrophages promote the invasion of breast carcinoma cells via a colony-stimulating factor-1/epidermal growth factor paracrine loop. Cancer Res (2005) 4.33
CSF-1 regulation of the wandering macrophage: complexity in action. Trends Cell Biol (2004) 4.02
Colony-stimulating factor-1 in immunity and inflammation. Curr Opin Immunol (2005) 3.67
PU.1 and C/EBPalpha/beta convert fibroblasts into macrophage-like cells. Proc Natl Acad Sci U S A (2008) 3.35
M-CSF instructs myeloid lineage fate in single haematopoietic stem cells. Nature (2013) 2.74
Functional overlap but differential expression of CSF-1 and IL-34 in their CSF-1 receptor-mediated regulation of myeloid cells. J Leukoc Biol (2010) 2.71
Adult Langerhans cells derive predominantly from embryonic fetal liver monocytes with a minor contribution of yolk sac-derived macrophages. J Exp Med (2012) 2.69
IRF4 transcription factor-dependent CD11b+ dendritic cells in human and mouse control mucosal IL-17 cytokine responses. Immunity (2013) 2.69
Retinoblastoma promotes definitive erythropoiesis by repressing Id2 in fetal liver macrophages. Nature (2004) 2.49
Invasion of human breast cancer cells in vivo requires both paracrine and autocrine loops involving the colony-stimulating factor-1 receptor. Cancer Res (2009) 2.25
Colony-stimulating factor-1 blockade by antisense oligonucleotides and small interfering RNAs suppresses growth of human mammary tumor xenografts in mice. Cancer Res (2004) 2.12
Draper-dependent glial phagocytic activity is mediated by Src and Syk family kinase signalling. Nature (2008) 2.06
Cyclin D1 regulates cellular migration through the inhibition of thrombospondin 1 and ROCK signaling. Mol Cell Biol (2006) 1.95
Regulation of lamellipodial persistence, adhesion turnover, and motility in macrophages by focal adhesion kinase. J Cell Biol (2007) 1.93
Colony stimulating factor-1 dependence of paneth cell development in the mouse small intestine. Gastroenterology (2009) 1.82
Pretransplant CSF-1 therapy expands recipient macrophages and ameliorates GVHD after allogeneic hematopoietic cell transplantation. J Exp Med (2011) 1.78
Cyclin D1 governs adhesion and motility of macrophages. Mol Biol Cell (2003) 1.71
Colony-stimulating factor-1 antibody reverses chemoresistance in human MCF-7 breast cancer xenografts. Cancer Res (2006) 1.67
CSF-1 signals directly to renal tubular epithelial cells to mediate repair in mice. J Clin Invest (2009) 1.66
Microglial stimulation of glioblastoma invasion involves epidermal growth factor receptor (EGFR) and colony stimulating factor 1 receptor (CSF-1R) signaling. Mol Med (2012) 1.64
The EGF/CSF-1 paracrine invasion loop can be triggered by heregulin beta1 and CXCL12. Cancer Res (2009) 1.56
Colony-stimulating factor-1 transfection of myoblasts improves the repair of failing myocardium following autologous myoblast transplantation. Cardiovasc Res (2008) 1.54
The CSF-1 receptor ligands IL-34 and CSF-1 exhibit distinct developmental brain expression patterns and regulate neural progenitor cell maintenance and maturation. Dev Biol (2012) 1.50
CSF-1 receptor-mediated differentiation of a new type of monocytic cell with B cell-stimulating activity: its selective dependence on IL-34. J Leukoc Biol (2013) 1.47
Mutation of mouse Mayp/Pstpip2 causes a macrophage autoinflammatory disease. Blood (2006) 1.44
Anthrax lethal toxin triggers the formation of a membrane-associated inflammasome complex in murine macrophages. Infect Immun (2009) 1.34
Osteoclast deficiency results in disorganized matrix, reduced mineralization, and abnormal osteoblast behavior in developing bone. J Bone Miner Res (2004) 1.25
The PCH family member MAYP/PSTPIP2 directly regulates F-actin bundling and enhances filopodia formation and motility in macrophages. Mol Biol Cell (2005) 1.22
Colony-stimulating factor-1 antisense treatment suppresses growth of human tumor xenografts in mice. Cancer Res (2002) 1.22
Pombe Cdc15 homology (PCH) proteins: coordinators of membrane-cytoskeletal interactions. Trends Cell Biol (2007) 1.21
BCL-6 negatively regulates macrophage proliferation by suppressing autocrine IL-6 production. Blood (2004) 1.20
CSF-1 receptor structure/function in MacCsf1r-/- macrophages: regulation of proliferation, differentiation, and morphology. J Leukoc Biol (2008) 1.19
Primed innate immunity leads to autoinflammatory disease in PSTPIP2-deficient cmo mice. Blood (2009) 1.18
Circulating CSF-1 promotes monocyte and macrophage phenotypes that enhance lupus nephritis. J Am Soc Nephrol (2009) 1.18
Reduced macrophage recruitment, proliferation, and activation in colony-stimulating factor-1-deficient mice results in decreased tubular apoptosis during renal inflammation. J Immunol (2003) 1.18
Removal of detergents from protein digests for mass spectrometry analysis. Anal Biochem (2008) 1.17
BCL-6 negatively regulates expression of the NF-kappaB1 p105/p50 subunit. J Immunol (2005) 1.16
PU.1-mediated upregulation of CSF1R is crucial for leukemia stem cell potential induced by MOZ-TIF2. Nat Med (2010) 1.12
Adenosine A1 receptors (A1Rs) play a critical role in osteoclast formation and function. FASEB J (2010) 1.12
Proteomic approaches to the analysis of early events in colony-stimulating factor-1 signal transduction. Mol Cell Proteomics (2003) 1.06
Contribution of CXCL12 secretion to invasion of breast cancer cells. Breast Cancer Res (2012) 1.05
PSTPIP2 deficiency in mice causes osteopenia and increased differentiation of multipotent myeloid precursors into osteoclasts. Blood (2012) 1.04
Negative role of colony-stimulating factor-1 in macrophage, T cell, and B cell mediated autoimmune disease in MRL-Fas(lpr) mice. J Immunol (2004) 1.03
Stromal cell-derived CSF-1 blockade prolongs xenograft survival of CSF-1-negative neuroblastoma. Int J Cancer (2010) 1.03
T-cell protein tyrosine phosphatase (Tcptp) is a negative regulator of colony-stimulating factor 1 signaling and macrophage differentiation. Mol Cell Biol (2006) 1.02
Sunlight triggers cutaneous lupus through a CSF-1-dependent mechanism in MRL-Fas(lpr) mice. J Immunol (2008) 1.02
A solution for stripping antibodies from polyvinylidene fluoride immunoblots for multiple reprobing. Anal Biochem (2009) 1.01
Critical roles for macrophages in islet angiogenesis and maintenance during pancreatic degeneration. Diabetes (2008) 0.99
Modulation of CSF-1-regulated post-natal development with anti-CSF-1 antibody. Immunobiology (2005) 0.98
Developmental and functional significance of the CSF-1 proteoglycan chondroitin sulfate chain. Blood (2005) 0.96
Macrophage proliferation is regulated through CSF-1 receptor tyrosines 544, 559, and 807. J Biol Chem (2012) 0.96
Phosphorylation of CSF-1R Y721 mediates its association with PI3K to regulate macrophage motility and enhancement of tumor cell invasion. J Cell Sci (2011) 0.95
Transgenic expression of CSF-1 in CSF-1 receptor-expressing cells leads to macrophage activation, osteoporosis, and early death. J Leukoc Biol (2006) 0.94
BCL6 suppresses RhoA activity to alter macrophage morphology and motility. J Cell Sci (2005) 0.94
Expression and tyrosine phosphorylation of Cbl regulates macrophage chemokinetic and chemotactic movement. J Cell Physiol (2003) 0.92
Receptor-type protein-tyrosine phosphatase ζ is a functional receptor for interleukin-34. J Biol Chem (2013) 0.91
Colony-stimulating factor-1 mediates macrophage-related neural damage in a model for Charcot-Marie-Tooth disease type 1X. Brain (2011) 0.90
Distinct in vivo roles of colony-stimulating factor-1 isoforms in renal inflammation. J Immunol (2006) 0.90
Distinct roles of CSF-1 isoforms in lupus nephritis. J Am Soc Nephrol (2011) 0.89
Drosophila Dok is required for embryonic dorsal closure. Development (2005) 0.89
A CSF-1 receptor phosphotyrosine 559 signaling pathway regulates receptor ubiquitination and tyrosine phosphorylation. J Biol Chem (2010) 0.88
Dendritic cell-mediated in vivo bone resorption. J Immunol (2010) 0.87
The CSF-1 receptor fashions the intestinal stem cell niche. Stem Cell Res (2012) 0.85
CSF-1 receptor-dependent colon development, homeostasis and inflammatory stress response. PLoS One (2013) 0.84
Essential role of Drosophila black-pearl is mediated by its effects on mitochondrial respiration. FASEB J (2012) 0.83
Rapid detergent removal from peptide samples with ethyl acetate for mass spectrometry analysis. Curr Protoc Protein Sci (2010) 0.83
Fes tyrosine kinase expression in the tumor niche correlates with enhanced tumor growth, angiogenesis, circulating tumor cells, metastasis, and infiltrating macrophages. Cancer Res (2010) 0.82
Specific inhibition of PI3K p110δ inhibits CSF-1-induced macrophage spreading and invasive capacity. FEBS J (2013) 0.81
Essential role of PU.1 in maintenance of mixed lineage leukemia-associated leukemic stem cells. Cancer Sci (2015) 0.78
Donor and recipient cell surface colony stimulating factor-1 promote neointimal formation in transplant-associated arteriosclerosis. Arterioscler Thromb Vasc Biol (2012) 0.78
Measurement of macrophage growth and differentiation. Curr Protoc Immunol (2011) 0.76
Special Issue Collection: In Memoriam. Stem Cells (2015) 0.75
Crosstalk between Muscularis Macrophages and Enteric Neurons Regulates Gastrointestinal Motility. Cell (2014) 0.75