Published in J Allergy Clin Immunol on October 01, 2003
Genetics of Asthma and Bronchial Hyperresponsiveness | NCT00005359
Polymorphisms associated with asthma are inversely related to glioblastoma multiforme. Cancer Res (2005) 2.11
Asthma in Hispanics. Am J Respir Crit Care Med (2005) 1.84
Contribution of ADAM33 polymorphisms to the population risk of asthma. Thorax (2005) 1.76
Sequence, haplotype, and association analysis of ADRbeta2 in a multiethnic asthma case-control study. Am J Respir Crit Care Med (2006) 1.59
The role of the epithelium in airway remodeling in asthma. Proc Am Thorac Soc (2009) 1.52
Asthma and ethnic minorities: socioeconomic status and beyond. Curr Opin Allergy Clin Immunol (2009) 1.38
Unifying candidate gene and GWAS Approaches in Asthma. PLoS One (2010) 1.36
Comprehensive testing of positionally cloned asthma genes in two populations. Am J Respir Crit Care Med (2007) 1.32
Adam33 polymorphisms are associated with COPD and lung function in long-term tobacco smokers. Respir Res (2009) 1.25
ADAM33 is not essential for growth and development and does not modulate allergic asthma in mice. Mol Cell Biol (2006) 1.15
Genetic variations in GRIA1 on chromosome 5q33 related to asparaginase hypersensitivity. Clin Pharmacol Ther (2010) 1.15
Race, ethnicity and social class and the complex etiologies of asthma. Pharmacogenomics (2008) 1.09
ADAM33, a new candidate for psoriasis susceptibility. PLoS One (2007) 1.08
A disintegrin and metalloprotease 33 and chronic obstructive pulmonary disease pathophysiology. Thorax (2006) 1.05
The role of polymorphisms in ADAM33, a disintegrin and metalloprotease 33, in childhood asthma and lung function in two German populations. Respir Res (2006) 1.04
Association of ADAM33 gene polymorphisms with adult allergic asthma and rhinitis in a Chinese Han population. BMC Med Genet (2008) 1.02
Role of ADAM and ADAMTS metalloproteinases in airway diseases. Respir Res (2009) 0.95
Association of IL-4 and ADAM33 gene polymorphisms with asthma in an Indian population. Lung (2010) 0.94
A Six-SNP haplotype of ADAM33 is associated with asthma in a population of Cartagena, Colombia. Int Arch Allergy Immunol (2009) 0.90
Unraveling the genetic basis of asthma and allergic diseases. Allergy Asthma Immunol Res (2010) 0.89
Analysis of polymorphisms in 16 genes in type 1 diabetes that have been associated with other immune-mediated diseases. BMC Med Genet (2006) 0.88
Association of ADAM33 gene polymorphisms with COPD in a northeastern Chinese population. BMC Med Genet (2009) 0.88
ADAM8: a new therapeutic target for asthma. Expert Opin Ther Targets (2009) 0.86
Mapping and identifying genes for asthma and psoriasis. Philos Trans R Soc Lond B Biol Sci (2005) 0.86
Evaluation of genetic susceptibility to childhood allergy and asthma in an African American urban population. BMC Med Genet (2011) 0.85
Differential desensitization of homozygous haplotypes of the beta2-adrenergic receptor in lymphocytes. Am J Respir Crit Care Med (2005) 0.85
DNA sequence variations of metalloproteinases: their role in asthma and COPD. Postgrad Med J (2007) 0.85
Role of ADAM33 gene and associated single nucleotide polymorphisms in asthma. Allergy Rhinol (Providence) (2011) 0.85
ADAM33 polymorphisms are associated with asthma and a distinctive palm dermatoglyphic pattern. Mol Med Rep (2013) 0.84
An ADAM33 polymorphism associates with progression of preschool wheeze into childhood asthma: a prospective case-control study with replication in a birth cohort study. PLoS One (2015) 0.81
Association between ADAM33 T1 polymorphism and susceptibility to asthma in Asians. Inflamm Res (2012) 0.80
Association study on ADAM33 polymorphisms in mite-sensitized persistent allergic rhinitis in a Chinese population. PLoS One (2014) 0.79
Association of ADAM33 gene polymorphisms with asthma in the Uygur population of China. Biomed Rep (2013) 0.78
Profile of gene expression in a murine model of allergic bronchopulmonary aspergillosis. Infect Immun (2005) 0.78
ADAM metallopeptidase domain 33 (ADAM33): a promising target for asthma. Mediators Inflamm (2014) 0.78
Mechanistic role of a disease-associated genetic variant within the ADAM33 asthma susceptibility gene. BMC Med Genet (2007) 0.78
Unravelling the role of ADAM 33 in asthma. Indian J Med Res (2013) 0.77
Genetic polymorphisms and asthma: findings from a case-control study in the Madeira island population. Biol Res (2014) 0.76
Policy implications of genetic information on regulation under the Clean Air Act: the case of particulate matter and asthmatics. Environ Health Perspect (2006) 0.76
ADAM33 gene polymorphisms identified to be associated with asthma in a Chinese Li population. Biomed Rep (2017) 0.75
Association of ADAM33 gene polymorphisms with allergic asthma. Iran J Basic Med Sci (2014) 0.75
Implications of population structure and ancestry on asthma genetic studies. Curr Opin Allergy Clin Immunol (2014) 0.75
Association of a disintegrin and metalloprotease 33 gene polymorphisms with asthma. Mol Clin Oncol (2014) 0.75
A disintegrin and metalloprotease 33 polymorphism association with COPD in long-term tobacco smokers of the ethnic Kashmiri population of India. Lung India (2015) 0.75
ADAM33 polymorphisms and susceptibility to allergic rhinitis: a meta-analysis. Eur Arch Otorhinolaryngol (2014) 0.75
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08
Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01
Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24. Nat Genet (2007) 19.18
Cumulative association of five genetic variants with prostate cancer. N Engl J Med (2008) 15.34
Inflammation in prostate carcinogenesis. Nat Rev Cancer (2007) 9.08
The Salmeterol Multicenter Asthma Research Trial: a comparison of usual pharmacotherapy for asthma or usual pharmacotherapy plus salmeterol. Chest (2006) 8.43
International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma. Eur Respir J (2013) 8.39
Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program. Am J Respir Crit Care Med (2009) 7.17
Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction. Nat Genet (2009) 6.83
Copy number analysis indicates monoclonal origin of lethal metastatic prostate cancer. Nat Med (2009) 6.61
Characterization of the severe asthma phenotype by the National Heart, Lung, and Blood Institute's Severe Asthma Research Program. J Allergy Clin Immunol (2007) 6.33
Tiotropium bromide step-up therapy for adults with uncontrolled asthma. N Engl J Med (2010) 6.19
Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer. Nat Genet (2008) 6.10
Mepolizumab for severe eosinophilic asthma (DREAM): a multicentre, double-blind, placebo-controlled trial. Lancet (2012) 5.82
Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array. Nat Genet (2013) 5.58
Germline mutations in HOXB13 and prostate-cancer risk. N Engl J Med (2012) 5.49
Two genome-wide association studies of aggressive prostate cancer implicate putative prostate tumor suppressor gene DAB2IP. J Natl Cancer Inst (2007) 4.85
Development, validity and responsiveness of the Clinical COPD Questionnaire. Health Qual Life Outcomes (2003) 4.41
Association between two unlinked loci at 8q24 and prostate cancer risk among European Americans. J Natl Cancer Inst (2007) 4.24
Androgen-induced TOP2B-mediated double-strand breaks and prostate cancer gene rearrangements. Nat Genet (2010) 3.83
Identification of a new prostate cancer susceptibility locus on chromosome 8q24. Nat Genet (2009) 3.76
Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. Nat Genet (2011) 3.68
Estrogen-receptor polymorphisms and effects of estrogen replacement on high-density lipoprotein cholesterol in women with coronary disease. N Engl J Med (2002) 3.68
Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase. Nat Med (2012) 3.21
Evidence for two independent prostate cancer risk-associated loci in the HNF1B gene at 17q12. Nat Genet (2008) 3.14
Uniform definition of asthma severity, control, and exacerbations: document presented for the World Health Organization Consultation on Severe Asthma. J Allergy Clin Immunol (2010) 3.12
Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function. Nat Genet (2011) 3.03
Oral or IV prednisolone in the treatment of COPD exacerbations: a randomized, controlled, double-blind study. Chest (2007) 2.96
The Scientific Foundation for personal genomics: recommendations from a National Institutes of Health-Centers for Disease Control and Prevention multidisciplinary workshop. Genet Med (2009) 2.91
Lung function in adults with stable but severe asthma: air trapping and incomplete reversal of obstruction with bronchodilation. J Appl Physiol (1985) (2007) 2.83
Lung function decline in male heavy smokers relates to baseline airflow obstruction severity. Chest (2012) 2.77
Germline mutations and sequence variants of the macrophage scavenger receptor 1 gene are associated with prostate cancer risk. Nat Genet (2002) 2.76
Genome-wide association study of prostate cancer in men of African ancestry identifies a susceptibility locus at 17q21. Nat Genet (2011) 2.70
Meta-analysis identifies common variants associated with body mass index in east Asians. Nat Genet (2012) 2.70
Polygenic risk score improves prostate cancer risk prediction: results from the Stockholm-1 cohort study. Eur Urol (2011) 2.62
Gene-gene interaction in asthma: IL4RA and IL13 in a Dutch population with asthma. Am J Hum Genet (2001) 2.61
A genome-wide association meta-analysis identifies new childhood obesity loci. Nat Genet (2012) 2.60
A randomized, double-blind, placebo-controlled study of tumor necrosis factor-alpha blockade in severe persistent asthma. Am J Respir Crit Care Med (2009) 2.56
Genome-wide association study of asthma identifies RAD50-IL13 and HLA-DR/DQ regions. J Allergy Clin Immunol (2010) 2.51
Genome-wide association study identifies new prostate cancer susceptibility loci. Hum Mol Genet (2011) 2.51
Exome sequencing identifies truncating mutations in PRRT2 that cause paroxysmal kinesigenic dyskinesia. Nat Genet (2011) 2.48
Effect of SCH55700, a humanized anti-human interleukin-5 antibody, in severe persistent asthma: a pilot study. Am J Respir Crit Care Med (2003) 2.45
Effect of ADRB2 polymorphisms on response to longacting beta2-agonist therapy: a pharmacogenetic analysis of two randomised studies. Lancet (2007) 2.41
Mode and place of delivery, gastrointestinal microbiota, and their influence on asthma and atopy. J Allergy Clin Immunol (2011) 2.39
Comparison of childhood wheezing phenotypes in 2 birth cohorts: ALSPAC and PIAMA. J Allergy Clin Immunol (2011) 2.38
Overweight and changes in weight status during childhood in relation to asthma symptoms at 8 years of age. J Allergy Clin Immunol (2009) 2.37
DNA copy number alterations in prostate cancers: a combined analysis of published CGH studies. Prostate (2007) 2.37
PTEN protein loss by immunostaining: analytic validation and prognostic indicator for a high risk surgical cohort of prostate cancer patients. Clin Cancer Res (2011) 2.35
Potential impact of adding genetic markers to clinical parameters in predicting prostate biopsy outcomes in men following an initial negative biopsy: findings from the REDUCE trial. Eur Urol (2012) 2.34
Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight. Nat Genet (2010) 2.30
Sequence variants at 22q13 are associated with prostate cancer risk. Cancer Res (2009) 2.27
Heterogeneity of severe asthma in childhood: confirmation by cluster analysis of children in the National Institutes of Health/National Heart, Lung, and Blood Institute Severe Asthma Research Program. J Allergy Clin Immunol (2010) 2.27
Beta2-receptor polymorphisms in patients receiving salmeterol with or without fluticasone propionate. Am J Respir Crit Care Med (2009) 2.27
Association between genetic polymorphisms in the prostate-specific antigen gene promoter and serum prostate-specific antigen levels. J Natl Cancer Inst (2003) 2.26
Adipocyte NCoR knockout decreases PPARγ phosphorylation and enhances PPARγ activity and insulin sensitivity. Cell (2011) 2.26
Design and baseline characteristics of the epidemiology and natural history of asthma: Outcomes and Treatment Regimens (TENOR) study: a large cohort of patients with severe or difficult-to-treat asthma. Ann Allergy Asthma Immunol (2004) 2.22
CT-quantified emphysema in male heavy smokers: association with lung function decline. Thorax (2011) 2.20
Analyses of asthma severity phenotypes and inflammatory proteins in subjects stratified by sputum granulocytes. J Allergy Clin Immunol (2010) 2.20
Universal risk factors for multifactorial diseases: LifeLines: a three-generation population-based study. Eur J Epidemiol (2007) 2.18