Published in Science on October 24, 2003
A genomic pathway approach to a complex disease: axon guidance and Parkinson disease. PLoS Genet (2007) 3.28
Hemophilic siblings with chronic hepatitis C: Familial aggregation of spontaneous and treatment-related viral clearance. Gastroenterology (2006) 2.04
Future health applications of genomics: priorities for communication, behavioral, and social sciences research. Am J Prev Med (2010) 1.98
Genetic linkage to chromosome 22q12 for a heavy-smoking quantitative trait in two independent samples. Am J Hum Genet (2007) 1.73
Maximizing resilience through diverse levels of inquiry: Prevailing paradigms, possibilities, and priorities for the future. Dev Psychopathol (2007) 1.48
Debating clinical utility. Public Health Genomics (2010) 1.41
The economic value of personalized medicine tests: what we know and what we need to know. Genet Med (2013) 1.40
Current priorities for public health practice in addressing the role of human genomics in improving population health. Am J Prev Med (2011) 1.36
Convergence of genetic findings for nicotine dependence and smoking related diseases with chromosome 15q24-25. Trends Pharmacol Sci (2009) 1.35
The genetics of addiction-a translational perspective. Transl Psychiatry (2012) 1.30
Blazing a trail: a public health research agenda in genomics and chronic disease. Prev Chronic Dis (2005) 1.21
Genetics of nicotine dependence and pharmacotherapy. Biochem Pharmacol (2007) 1.21
Gene-environment interaction effects on the development of immune responses in the 1st year of life. Am J Hum Genet (2005) 1.19
Study designs for identification of rare disease variants in complex diseases: the utility of family-based designs. Genetics (2011) 1.14
Newborn screening: complexities in universal genetic testing. Am J Public Health (2006) 1.13
Framing Nicotine Addiction as a "Disease of the Brain": Social and Ethical Consequences. Soc Sci Q (2011) 1.10
Challenges to the translation of genomic information into clinical practice and health policy: Utilization, preferences and economic value. Curr Opin Mol Ther (2008) 1.08
Integrated analysis of independent gene expression microarray datasets improves the predictability of breast cancer outcome. BMC Genomics (2007) 1.05
Type 2 diabetes and obesity: genomics and the clinic. Hum Genet (2011) 1.04
Realizing the promise of population biobanks: a new model for translation. Hum Genet (2011) 0.99
'To prove this is the industry's best hope': big tobacco's support of research on the genetics of nicotine addiction. Addiction (2010) 0.94
Neural plasticity, human genetics, and risk for alcohol dependence. Int Rev Neurobiol (2010) 0.94
Implications of genome wide association studies for addiction: are our a priori assumptions all wrong? Pharmacol Ther (2013) 0.93
Symbiotic relationship of pharmacogenetics and drugs of abuse. AAPS J (2006) 0.93
The effect of parental modeling of anxious behaviors and cognitions in school-aged children: an experimental pilot study. Behav Res Ther (2010) 0.90
Systems biology: new approaches to old environmental health problems. Int J Environ Res Public Health (2005) 0.90
Insights into the genetic basis of type 2 diabetes. J Diabetes Investig (2013) 0.90
The developmental behavior genetics of drug involvement: overview and comments. Behav Genet (2006) 0.89
Brain electrophysiological endophenotypes for externalizing psychopathology: a multivariate approach. Behav Genet (2010) 0.88
Pharmacogenetics of smoking cessation in general practice: results from the patch II and patch in practice trials. Nicotine Tob Res (2011) 0.88
Dopamine genes and schizophrenia: case closed or evidence pending? Schizophr Bull (2007) 0.88
Pharmacogenetics: data, concepts and tools to improve drug discovery and drug treatment. Eur J Clin Pharmacol (2008) 0.86
Setting priorities for genomic research. Science (2004) 0.86
The Genetics, Neurogenetics and Pharmacogenetics of Addiction. Curr Behav Neurosci Rep (2014) 0.83
Genetic research participation in a young adult community sample. J Community Genet (2014) 0.83
The prediction of disease risk in genomic medicine. EMBO Rep (2004) 0.83
Integrating genetic studies of nicotine addiction into public health practice: stakeholder views on challenges, barriers and opportunities. Public Health Genomics (2011) 0.80
Public health genomics and genetic test evaluation: the challenge of conducting behavioural research on the utility of lifestyle-genetic tests. J Nutrigenet Nutrigenomics (2008) 0.80
Things that kept coming to mind while thinking through Susser's South African memoir. J Epidemiol Community Health (2006) 0.79
Challenges in translational research: the views of addiction scientists. PLoS One (2014) 0.77
Unwarranted optimism in media portrayals of genetic research on addiction overshadows critical ethical and social concerns. J Health Commun (2015) 0.77
A research agenda for assessing the potential contribution of genomic medicine to tobacco control. Tob Control (2007) 0.77
Policy implications of genetic information on regulation under the Clean Air Act: the case of particulate matter and asthmatics. Environ Health Perspect (2006) 0.76
Assessing the social meaning, value and implications of research in genomics. J Epidemiol Community Health (2007) 0.75
The media and behavioral genetics: Alternatives coexisting with addiction genetics. Sci Technol Human Values (2015) 0.75
William Allan Award Address: On the role and soul of a statistical geneticist. Am J Hum Genet (2011) 0.75
Genetic research on nicotine dependence will facilitate public health. PLoS Med (2005) 0.75
Genome-Wide Association Study for Autism Spectrum Disorder in Taiwanese Han Population. PLoS One (2015) 0.75
Two-way communication between genomics and society. Science & Society Series on Convergence Research. EMBO Rep (2009) 0.75
The Contribution of the Framingham Heart Study to Gene Identification for Cardiovascular Risk Factors and Coronary Heart Disease. Glob Heart (2013) 0.75
The Efficacy of Genetic Counseling for Psychiatric Disorders: a Meta-Analysis. J Genet Couns (2017) 0.75
High resolution analysis of rare copy number variants in patients with autism spectrum disorder from Taiwan. Sci Rep (2017) 0.75
Discovering genotypes underlying human phenotypes: past successes for mendelian disease, future approaches for complex disease. Nat Genet (2003) 13.60
The importance of race and ethnic background in biomedical research and clinical practice. N Engl J Med (2003) 7.94
Genetic heritability and shared environmental factors among twin pairs with autism. Arch Gen Psychiatry (2011) 6.98
Admixture mapping for hypertension loci with genome-scan markers. Nat Genet (2005) 6.78
Reconstructing genetic ancestry blocks in admixed individuals. Am J Hum Genet (2006) 5.92
Natural variation in human membrane transporter genes reveals evolutionary and functional constraints. Proc Natl Acad Sci U S A (2003) 5.77
Positional cloning of the human quantitative trait locus underlying taste sensitivity to phenylthiocarbamide. Science (2003) 4.48
LRRK2 G2019S as a cause of Parkinson's disease in Ashkenazi Jews. N Engl J Med (2006) 3.90
A highly significant association between a COMT haplotype and schizophrenia. Am J Hum Genet (2002) 3.52
Latino populations: a unique opportunity for the study of race, genetics, and social environment in epidemiological research. Am J Public Health (2005) 3.50
Parent-of-origin effect in multiple sclerosis: observations in half-siblings. Lancet (2004) 3.47
Narcolepsy is strongly associated with the T-cell receptor alpha locus. Nat Genet (2009) 3.33
Population stratification confounds genetic association studies among Latinos. Hum Genet (2005) 3.19
Homozygosity and linkage disequilibrium. Genetics (2002) 3.04
Susceptibility locus for clinical and subclinical coronary artery disease at chromosome 9p21 in the multi-ethnic ADVANCE study. Hum Mol Genet (2008) 2.71
Next generation genome-wide association tool: design and coverage of a high-throughput European-optimized SNP array. Genomics (2011) 2.31
Complex interactions among MHC haplotypes in multiple sclerosis: susceptibility and resistance. Hum Mol Genet (2005) 2.26
Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies. J Am Coll Cardiol (2010) 2.17
Will the genomics revolution revolutionize psychiatry? Am J Psychiatry (2003) 2.11
Global transcriptional response to interferon is a determinant of HCV treatment outcome and is modified by race. Hepatology (2006) 2.03
Characterizing the admixed African ancestry of African Americans. Genome Biol (2009) 2.01
Racial admixture and its impact on BMI and blood pressure in African and Mexican Americans. Hum Genet (2006) 1.98
Estimating kinship in admixed populations. Am J Hum Genet (2012) 1.95
Admixture mapping and the role of population structure for localizing disease genes. Adv Genet (2008) 1.76
Behavioral phenotypic variation in autism multiplex families: evidence for a continuous severity gradient. Am J Med Genet (2002) 1.71
Common variants in P2RY11 are associated with narcolepsy. Nat Genet (2010) 1.65
Assessing genetic contributions to phenotypic differences among 'racial' and 'ethnic' groups. Nat Genet (2004) 1.62
Narrowing the DYT6 dystonia region and evidence for locus heterogeneity in the Amish-Mennonites. Am J Med Genet A (2007) 1.61
Mutation frequencies for glycogen storage disease Ia in the Ashkenazi Jewish population. Am J Med Genet A (2004) 1.59
Partial deficiency of the C-terminal-domain phosphatase of RNA polymerase II is associated with congenital cataracts facial dysmorphism neuropathy syndrome. Nat Genet (2003) 1.57
History shaped the geographic distribution of genomic admixture on the island of Puerto Rico. PLoS One (2011) 1.50
Ethnicity and human genetic linkage maps. Am J Hum Genet (2004) 1.50
A polymorphism in the beta1 adrenergic receptor is associated with resting heart rate. Am J Hum Genet (2002) 1.46
On the twin risk in autism. Am J Hum Genet (2002) 1.40
Dropped genetics paper lacked scientific merit. Nature (2002) 1.39
Human genetic variation recognizes functional elements in noncoding sequence. Genome Res (2009) 1.33
The epilepsy phenome/genome project. Clin Trials (2013) 1.32
Functional genomics of membrane transporters in human populations. Genome Res (2005) 1.27
Differences in albuminuria between Hispanics and whites: an evaluation by genetic ancestry and country of origin: the multi-ethnic study of atherosclerosis. Circ Cardiovasc Genet (2010) 1.23
Dissecting racial and ethnic differences. N Engl J Med (2006) 1.19
Crohn disease: frequency and nature of CARD15 mutations in Ashkenazi and Sephardi/Oriental Jewish families. Am J Hum Genet (2004) 1.17
Admixture mapping of quantitative trait loci for BMI in African Americans: evidence for loci on chromosomes 3q, 5q, and 15q. Obesity (Silver Spring) (2009) 1.12
A meta-analysis of genome-wide linkage scans for hypertension: the National Heart, Lung and Blood Institute Family Blood Pressure Program. Am J Hypertens (2003) 1.07
A near null variant of 12/15-LOX encoded by a novel SNP in ALOX15 and the risk of coronary artery disease. Atherosclerosis (2007) 1.01
Genome-wide distribution of ancestry in Mexican Americans. Hum Genet (2008) 0.96
An extended genome scan in 442 Canadian multiple sclerosis-affected sibships: a report from the Canadian Collaborative Study Group. Hum Mol Genet (2004) 0.96
Common polymorphisms of ALOX5 and ALOX5AP and risk of coronary artery disease. Hum Genet (2008) 0.93
A genome scan for hypertension susceptibility loci in populations of Chinese and Japanese origins. Am J Hypertens (2003) 0.91
Lack of association between HoxA1 and HoxB1 gene variants and autism in 110 multiplex families. Am J Med Genet (2002) 0.90
Failure to replicate an association of SNPs in the oxidized LDL receptor gene (OLR1) with CAD. BMC Med Genet (2008) 0.89
The Association of African Ancestry and elevated creatinine in the Coronary Artery Risk Development in Young Adults (CARDIA) Study. Am J Nephrol (2009) 0.86
Lack of evidence for an association between WNT2 and RELN polymorphisms and autism. Am J Med Genet B Neuropsychiatr Genet (2004) 0.85
Response to Zhang et al. (2005): loss-of-function mutation in tryptophan hydroxylase-2 identified in unipolar major depression. Neuron 45, 11-16. Neuron (2005) 0.84
Genome-wide linkage analysis of lipids in nondiabetic Chinese and Japanese from the SAPPHIRe family study. Am J Hypertens (2006) 0.82
African American race but not genome-wide ancestry is negatively associated with atrial fibrillation among postmenopausal women in the Women's Health Initiative. Am Heart J (2013) 0.81
Haplotype structure and ethnic-specific allele frequencies at the OCTN locus: implications for the genetics of Crohn's disease. Inflamm Bowel Dis (2005) 0.81
Twins of mistaken zygosity (TOMZ): evidence for genetic contributions to dietary patterns and physiologic traits. Twin Res Hum Genet (2006) 0.76
Charles Joseph Epstein, M.D., 1933–2011, in memoriam. Am J Hum Genet (2011) 0.75
The whole side of it--an interview with Neil Risch. Interview by Jane Gitschier. PLoS Genet (2005) 0.75
The whole side of it--an interview with Neil Risch by Jane Gitschier. PLoS Genet (2005) 0.75