Published in J Am Chem Soc on November 12, 2003
Mechanisms and implications of transcription blockage by guanine-rich DNA sequences. Proc Natl Acad Sci U S A (2010) 1.55
Telomeric overhang length determines structural dynamics and accessibility to telomerase and ALT-associated proteins. Structure (2014) 1.54
Single-molecule detection of folding and unfolding of the G-quadruplex aptamer in a nanopore nanocavity. Nucleic Acids Res (2008) 1.22
The formation pathway of tetramolecular G-quadruplexes. Nucleic Acids Res (2007) 1.00
Crystallization and characterization of the thallium form of the Oxytricha nova G-quadruplex. Nucleic Acids Res (2006) 0.89
Thermodynamic characterization of specific interactions between the human Lon protease and G-quartet DNA. Nucleic Acids Res (2008) 0.86
Potassium ions modulate a G-quadruplex-ribozyme's activity. RNA (2008) 0.84
NMR evaluation of ammonium ion movement within a unimolecular G-quadruplex in solution. Nucleic Acids Res (2007) 0.83
Self-assembled cation transporters made from lipophilic 8-phenyl-2'-deoxyguanosine derivatives. Supramol Chem (2010) 0.79
Guanosine quadruplexes in solution: a small-angle x-ray scattering analysis of temperature effects on self-assembling of deoxyguanosine monophosphate. J Nucleic Acids (2010) 0.78
Tuning supramolecular G-quadruplexes with mono- and divalent cations. Supramol Chem (2014) 0.76
Effect of sequence and metal ions on UVB-induced anti cyclobutane pyrimidine dimer formation in human telomeric DNA sequences. Nucleic Acids Res (2014) 0.76
Distinct differences in metal ion specificity of RNA and DNA G-quadruplexes. J Biol Inorg Chem (2016) 0.75
Co-existence of distinct supramolecular assemblies in solution and in the solid state. Chemistry (2016) 0.75
Origin of Ion Specificity of Telomeric DNA G-Quadruplexes Investigated by Free-Energy Simulations. Biophys J (2017) 0.75
Control of bacterial nitrate assimilation by stabilization of G-quadruplex DNA. Chem Commun (Camb) (2016) 0.75
Folding and misfolding pathways of G-quadruplex DNA. Nucleic Acids Res (2016) 0.75
Differential stabilization of adenine quartets by anions and cations. J Biol Inorg Chem (2009) 0.75
Assembly of supramolecular DNA complexes containing both G-quadruplexes and i-motifs by enhancing the G-repeat-bearing capacity of i-motifs. Nucleic Acids Res (2016) 0.75
RNA G-quadruplexes in biology: Principles and molecular mechanisms. J Mol Biol (2017) 0.75
The genetic basis of early T-cell precursor acute lymphoblastic leukaemia. Nature (2012) 9.89
SGS3 and SGS2/SDE1/RDR6 are required for juvenile development and the production of trans-acting siRNAs in Arabidopsis. Genes Dev (2004) 8.18
An ordered, nonredundant library of Pseudomonas aeruginosa strain PA14 transposon insertion mutants. Proc Natl Acad Sci U S A (2006) 7.62
Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia. N Engl J Med (2014) 5.37
Discovery of dapagliflozin: a potent, selective renal sodium-dependent glucose cotransporter 2 (SGLT2) inhibitor for the treatment of type 2 diabetes. J Med Chem (2008) 5.15
A novel retinoblastoma therapy from genomic and epigenetic analyses. Nature (2012) 5.02
Novel mutations target distinct subgroups of medulloblastoma. Nature (2012) 4.82
Genomic analysis reveals that Pseudomonas aeruginosa virulence is combinatorial. Genome Biol (2006) 3.75
Nuclear processing and export of microRNAs in Arabidopsis. Proc Natl Acad Sci U S A (2005) 3.57
Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas. Nat Genet (2013) 3.51
The genomic landscape of hypodiploid acute lymphoblastic leukemia. Nat Genet (2013) 3.43
Key pathways are frequently mutated in high-risk childhood acute lymphoblastic leukemia: a report from the Children's Oncology Group. Blood (2011) 3.40
Trans-acting siRNA-mediated repression of ETTIN and ARF4 regulates heteroblasty in Arabidopsis. Development (2006) 2.93
A prospective, randomized study comparing outcomes and toxicities of intensity-modulated radiotherapy vs. conventional two-dimensional radiotherapy for the treatment of nasopharyngeal carcinoma. Radiother Oncol (2012) 2.54
Genome-wide association identifies a susceptibility locus for coronary artery disease in the Chinese Han population. Nat Genet (2011) 2.32
Deproteinized bovine bone functionalized with the slow delivery of BMP-2 for the repair of critical-sized bone defects in sheep. Bone (2013) 2.09
Identification of molecular pathway aberrations in uterine serous carcinoma by genome-wide analyses. J Natl Cancer Inst (2012) 2.09
The microRNA-regulated SBP-Box transcription factor SPL3 is a direct upstream activator of LEAFY, FRUITFULL, and APETALA1. Dev Cell (2009) 2.07
High-throughput screen for novel antimicrobials using a whole animal infection model. ACS Chem Biol (2009) 1.99
Genetic variations at loci involved in the immune response are risk factors for hepatocellular carcinoma. Hepatology (2010) 1.97
Correlation of mRNA expression and protein abundance affected by multiple sequence features related to translational efficiency in Desulfovibrio vulgaris: a quantitative analysis. Genetics (2006) 1.96
Meta-analysis of the prognostic value of circulating tumor cells in breast cancer. Clin Cancer Res (2012) 1.79
Correlation between mRNA and protein abundance in Desulfovibrio vulgaris: a multiple regression to identify sources of variations. Biochem Biophys Res Commun (2005) 1.73
An Inv(16)(p13.3q24.3)-encoded CBFA2T3-GLIS2 fusion protein defines an aggressive subtype of pediatric acute megakaryoblastic leukemia. Cancer Cell (2012) 1.61
Cyclophilin 40 is required for microRNA activity in Arabidopsis. Proc Natl Acad Sci U S A (2009) 1.56
Integrative analysis of transcriptomic and proteomic data: challenges, solutions and applications. Crit Rev Biotechnol (2007) 1.56
N-(4-tertiarybutylphenyl)-4-(3-chloropyridin-2-yl)tetrahydropyrazine -1(2H)-carbox-amide (BCTC), a novel, orally effective vanilloid receptor 1 antagonist with analgesic properties: I. in vitro characterization and pharmacokinetic properties. J Pharmacol Exp Ther (2003) 1.56
Tyrosine kinome sequencing of pediatric acute lymphoblastic leukemia: a report from the Children's Oncology Group TARGET Project. Blood (2012) 1.47
New covered mushroom-shaped metallic stent for managing anastomotic leak after esophagogastrostomy with a wide gastric tube. Ann Thorac Surg (2006) 1.47
Glycemic variability in gestational diabetes mellitus and its association with β cell function. Endocrine (2012) 1.46
Candidate pathway-based genome-wide association studies identify novel associations of genomic variants in the complement system associated with coronary artery disease. Circ Cardiovasc Genet (2014) 1.45
Primitive neuroectodermal tumor of the kidney with inferior vena cava tumor thrombus. J Natl Med Assoc (2009) 1.43
A novel approach: treatment of bronchial stump fistula with a plugged, bullet-shaped, angled stent. Ann Thorac Surg (2006) 1.42
Acquired cisplatin resistance in human lung adenocarcinoma cells is associated with enhanced autophagy. Cancer Biother Radiopharm (2010) 1.33
Degradation of petroleum hydrocarbons (C6-C40) and crude oil by a novel Dietzia strain. Bioresour Technol (2011) 1.29
MicroRNA-34a inhibits migration and invasion of colon cancer cells via targeting to Fra-1. Carcinogenesis (2011) 1.29
Effect of lipid-bound apoA-I cysteine mutants on lipopolysaccharide-induced endotoxemia in mice. J Lipid Res (2008) 1.28
Assessment of association of rs2200733 on chromosome 4q25 with atrial fibrillation and ischemic stroke in a Chinese Han population. Hum Genet (2009) 1.25
Eremophilane-type sesquiterpene derivatives from the roots of Ligularia lapathifolia. J Nat Prod (2007) 1.24
Identification of antifungal compounds active against Candida albicans using an improved high-throughput Caenorhabditis elegans assay. PLoS One (2009) 1.22
Correcting diastolic dysfunction by Ca2+ desensitizing troponin in a transgenic mouse model of restrictive cardiomyopathy. J Mol Cell Cardiol (2010) 1.17
Biomimetic coatings for bone tissue engineering of critical-sized defects. J R Soc Interface (2010) 1.17
Mutations in the GW-repeat protein SUO reveal a developmental function for microRNA-mediated translational repression in Arabidopsis. Proc Natl Acad Sci U S A (2011) 1.16
Evolution of the syntrophic interaction between Desulfovibrio vulgaris and Methanosarcina barkeri: Involvement of an ancient horizontal gene transfer. Biochem Biophys Res Commun (2006) 1.13
Transcriptome analysis of leaf tissue of Raphanus sativus by RNA sequencing. PLoS One (2013) 1.11
Synthesis of isotopically labeled arachidonic acids to probe the reaction mechanism of prostaglandin H synthase. J Am Chem Soc (2002) 1.09
Significant association of SNP rs2106261 in the ZFHX3 gene with atrial fibrillation in a Chinese Han GeneID population. Hum Genet (2010) 1.09
Identification of NPPA variants associated with atrial fibrillation in a Chinese GeneID population. Clin Chim Acta (2010) 1.09
Integrated analysis of transcriptomic and proteomic data of Desulfovibrio vulgaris: zero-inflated Poisson regression models to predict abundance of undetected proteins. Bioinformatics (2006) 1.06
Analysis of myostatin gene structure, expression and function in zebrafish. J Exp Biol (2003) 1.06
Analysis of MDM2 and MDM4 single nucleotide polymorphisms, mRNA splicing and protein expression in retinoblastoma. PLoS One (2012) 1.06
Amplification of the ch19p13.2 NACC1 locus in ovarian high-grade serous carcinoma. Mod Pathol (2011) 1.05
Identification of Tyr504 as an alternative tyrosyl radical site in human prostaglandin H synthase-2. Biochemistry (2004) 1.05
Three different oxygen-induced radical species in endothelial nitric-oxide synthase oxygenase domain under regulation by L-arginine and tetrahydrobiopterin. J Biol Chem (2004) 1.05
Phylogenetic analysis using complete signature information of whole genomes and clustered Neighbour-Joining method. Int J Bioinform Res Appl (2006) 1.05
Functional dominant-negative mutation of sodium channel subunit gene SCN3B associated with atrial fibrillation in a Chinese GeneID population. Biochem Biophys Res Commun (2010) 1.03
Integrated cross-species transcriptional network analysis of metastatic susceptibility. Proc Natl Acad Sci U S A (2012) 1.03
The signaling and functions of heterodimeric bone morphogenetic proteins. Cytokine Growth Factor Rev (2012) 1.02
RNA interference in Nilaparvata lugens (Homoptera: Delphacidae) based on dsRNA ingestion. Pest Manag Sci (2011) 1.01
Optimal encoding rules for synthetic genes: the need for a community effort. Mol Syst Biol (2007) 1.01
Expression of CDK5/p35 in resected patients with non-small cell lung cancer: relation to prognosis. Med Oncol (2010) 1.01
MiR-200c increases the radiosensitivity of non-small-cell lung cancer cell line A549 by targeting VEGF-VEGFR2 pathway. PLoS One (2013) 1.00
DNA sequence analyses reveal abundant diversity, endemism and evidence for Asian origin of the porcini mushrooms. PLoS One (2012) 0.99
Changes of some anti-oxidative physiological indices under soil water deficits among 10 wheat (Triticum aestivum L.) genotypes at tillering stage. Colloids Surf B Biointerfaces (2006) 0.99
Direct NMR detection of alkali metal ions bound to G-quadruplex DNA. J Am Chem Soc (2008) 0.98
The general transcription factor TAF7 is essential for embryonic development but not essential for the survival or differentiation of mature T cells. Mol Cell Biol (2012) 0.98
Rice dwarf phytoreovirus segment S6-encoded nonstructural protein has a cell-to-cell movement function. J Virol (2004) 0.98
Retrieval stent filter: treatment of Budd Chiari syndrome complicated with inferior vena cava thrombosis--initial clinical experience. Ann Thorac Surg (2007) 0.98
Genipin-cross-linked collagen/chitosan biomimetic scaffolds for articular cartilage tissue engineering applications. J Biomed Mater Res A (2010) 0.98
Radiation induced temporal lobe necrosis in patients with nasopharyngeal carcinoma: a review of new avenues in its management. Radiat Oncol (2011) 0.98
Tissue factor as a link between wounding and tissue repair. Diabetes (2005) 0.97
Determination of the structural environment of the tyrosyl radical in prostaglandin H2 synthase-1: a high frequency ENDOR/EPR study. J Am Chem Soc (2005) 0.96
The IL-33-ST2L pathway is associated with coronary artery disease in a Chinese Han population. Am J Hum Genet (2013) 0.96
Li-rich anti-perovskite Li3OCl films with enhanced ionic conductivity. Chem Commun (Camb) (2014) 0.96
Tamoxifen alleviates irradiation-induced brain injury by attenuating microglial inflammatory response in vitro and in vivo. Brain Res (2010) 0.95
Regulation of CARD8 expression by ANRIL and association of CARD8 single nucleotide polymorphism rs2043211 (p.C10X) with ischemic stroke. Stroke (2014) 0.95
Assessing telomeric DNA content in pediatric cancers using whole-genome sequencing data. Genome Biol (2012) 0.95
Disodium guanosine 5'-monophosphate self-associates into nanoscale cylinders at pH 8: a combined diffusion NMR spectroscopy and dynamic light scattering study. J Am Chem Soc (2005) 0.94
Divergent polyamine metabolism in the Apicomplexa. Microbiology (2007) 0.94
Expression of FOXJ1 in hepatocellular carcinoma: correlation with patients' prognosis and tumor cell proliferation. Mol Carcinog (2012) 0.94
Role of different negative pressure values in the process of infected wounds treated by vacuum-assisted closure: an experimental study. Int Wound J (2012) 0.94
Structural characterization of arachidonyl radicals formed by aspirin-treated prostaglandin H synthase-2. J Biol Chem (2002) 0.93
Graphene/graphene-tube nanocomposites templated from cage-containing metal-organic frameworks for oxygen reduction in Li-O₂ batteries. Adv Mater (2013) 0.93
Large-scale synthesis and self-assembly of monodisperse hexagon Cu2S nanoplates. Langmuir (2005) 0.92
In vitro generation of osteochondral differentiation of human marrow mesenchymal stem cells in novel collagen-hydroxyapatite layered scaffolds. Acta Biomater (2011) 0.92
Rho kinase inhibitor fasudil suppresses migration and invasion though down-regulating the expression of VEGF in lung cancer cell line A549. Med Oncol (2010) 0.91
RiceWiki: a wiki-based database for community curation of rice genes. Nucleic Acids Res (2013) 0.91
Potential health impact on mice after nasal instillation of nano-sized copper particles and their translocation in mice. J Nanosci Nanotechnol (2009) 0.91
CIP2A is highly expressed in hepatocellular carcinoma and predicts poor prognosis. Diagn Mol Pathol (2012) 0.91
Feasibility and safety of transradial approach for catheter ablation of idiopathic left ventricular tachycardia. Clin Res Cardiol (2010) 0.90
Anti-inflammatory effects of tanshinone IIA on radiation-induced microglia BV-2 cells inflammatory response. Cancer Biother Radiopharm (2009) 0.90
Effect of age and extrinsic microenvironment on the proliferation and osteogenic differentiation of rat dental pulp stem cells in vitro. J Endod (2009) 0.90
Development and preclinical studies of broad-spectrum anti-HIV agent (3'R,4'R)-3-cyanomethyl-4-methyl-3',4'-di-O-(S)-camphanoyl-(+)-cis-khellactone (3-cyanomethyl-4-methyl-DCK). J Med Chem (2008) 0.90
Gastrotracheal and gastrobronchial fistulas: management with covered expandable metallic stents. J Vasc Interv Radiol (2006) 0.90
Field evaluation of effects of transgenic cry1Ab/cry1Ac, cry1C and cry2A rice on Cnaphalocrocis medinalis and its arthropod predators. Sci China Life Sci (2011) 0.90
Clinical applications of the C-arm cone-beam CT-based 3D needle guidance system in performing percutaneous transthoracic needle biopsy of pulmonary lesions. Diagn Interv Radiol (2014) 0.89
An integrated systems genetics screen reveals the transcriptional structure of inherited predisposition to metastatic disease. Genome Res (2013) 0.89
Experimental evolution of adenylate kinase reveals contrasting strategies toward protein thermostability. Biophys J (2010) 0.89
EGFR mutations in non-small-cell lung cancer among smokers and non-smokers: a meta-analysis. Environ Mol Mutagen (2011) 0.89
Nimotuzumab combined with radiotherapy for esophageal cancer: preliminary study of a Phase II clinical trial. Onco Targets Ther (2013) 0.89