Published in Cell on October 31, 2003
CLASP1 and CLASP2 bind to EB1 and regulate microtubule plus-end dynamics at the cell cortex. J Cell Biol (2005) 3.54
ACF7 regulates cytoskeletal-focal adhesion dynamics and migration and has ATPase activity. Cell (2008) 2.94
Focal adhesion kinase modulates tension signaling to control actin and focal adhesion dynamics. J Cell Biol (2007) 2.79
Skin stem cells orchestrate directional migration by regulating microtubule-ACF7 connections through GSK3β. Cell (2011) 2.36
Clostridium difficile toxin CDT induces formation of microtubule-based protrusions and increases adherence of bacteria. PLoS Pathog (2009) 2.29
Directing cell migration with asymmetric micropatterns. Proc Natl Acad Sci U S A (2005) 2.22
EB1 and EB3 control CLIP dissociation from the ends of growing microtubules. Mol Biol Cell (2005) 2.19
Structural determinants for EB1-mediated recruitment of APC and spectraplakins to the microtubule plus end. J Cell Biol (2005) 2.10
The formin mDia2 stabilizes microtubules independently of its actin nucleation activity. J Cell Biol (2008) 1.96
GSK3beta phosphorylation modulates CLASP-microtubule association and lamella microtubule attachment. J Cell Biol (2009) 1.95
Drugs that target dynamic microtubules: a new molecular perspective. Med Res Rev (2011) 1.70
The role of microtubule actin cross-linking factor 1 (MACF1) in the Wnt signaling pathway. Genes Dev (2006) 1.66
Targeting and transport: how microtubules control focal adhesion dynamics. J Cell Biol (2012) 1.62
The polarity protein Par6 induces cell proliferation and is overexpressed in breast cancer. Cancer Res (2008) 1.59
The formin mDia regulates GSK3beta through novel PKCs to promote microtubule stabilization but not MTOC reorientation in migrating fibroblasts. Mol Biol Cell (2006) 1.53
WNT-SHH Antagonism Specifies and Expands Stem Cells prior to Niche Formation. Cell (2016) 1.52
Anterograde microtubule transport drives microtubule bending in LLC-PK1 epithelial cells. Mol Biol Cell (2009) 1.41
Formins and microtubules. Biochim Biophys Acta (2009) 1.40
ErbB2 receptor controls microtubule capture by recruiting ACF7 to the plasma membrane of migrating cells. Proc Natl Acad Sci U S A (2010) 1.35
Control of microtubule organization and dynamics: two ends in the limelight. Nat Rev Mol Cell Biol (2015) 1.31
Septin GTPases spatially guide microtubule organization and plus end dynamics in polarizing epithelia. J Cell Biol (2011) 1.30
A matter of life and death: self-renewal in stem cells. EMBO Rep (2012) 1.30
+TIPs: SxIPping along microtubule ends. Trends Cell Biol (2012) 1.28
The Rho GTP exchange factor Lfc promotes spindle assembly in early mitosis. Proc Natl Acad Sci U S A (2005) 1.28
Mouse ACF7 and drosophila short stop modulate filopodia formation and microtubule organisation during neuronal growth. J Cell Sci (2009) 1.28
KIF17 stabilizes microtubules and contributes to epithelial morphogenesis by acting at MT plus ends with EB1 and APC. J Cell Biol (2010) 1.21
Force-induced cell polarisation is linked to RhoA-driven microtubule-independent focal-adhesion sliding. J Cell Sci (2009) 1.21
Coordinating cytoskeletal tracks to polarize cellular movements. J Cell Biol (2004) 1.20
MAP1B regulates axonal development by modulating Rho-GTPase Rac1 activity. Mol Biol Cell (2010) 1.17
The spectraplakin Short stop is an actin-microtubule cross-linker that contributes to organization of the microtubule network. Mol Biol Cell (2010) 1.17
Spectraplakins: master orchestrators of cytoskeletal dynamics. J Cell Biol (2012) 1.16
Effect of GFP tags on the localization of EB1 and EB1 fragments in vivo. Cytoskeleton (Hoboken) (2010) 1.15
GTSE1 is a microtubule plus-end tracking protein that regulates EB1-dependent cell migration. PLoS One (2012) 1.12
The contribution of αβ-tubulin curvature to microtubule dynamics. J Cell Biol (2014) 1.11
Finding the cell center by a balance of dynein and myosin pulling and microtubule pushing: a computational study. Mol Biol Cell (2010) 1.11
Microtubule plus-ends within a mitotic cell are 'moving platforms' with anchoring, signalling and force-coupling roles. Open Biol (2012) 1.10
Eukaryotic cells and their cell bodies: Cell Theory revised. Ann Bot (2004) 1.10
Tao-1 is a negative regulator of microtubule plus-end growth. J Cell Sci (2010) 1.08
Microtubule actin crosslinking factor 1 regulates the Balbiani body and animal-vegetal polarity of the zebrafish oocyte. PLoS Genet (2010) 1.08
Spectraplakins promote microtubule-mediated axonal growth by functioning as structural microtubule-associated proteins and EB1-dependent +TIPs (tip interacting proteins). J Neurosci (2012) 1.07
Dissecting the nanoscale distributions and functions of microtubule-end-binding proteins EB1 and ch-TOG in interphase HeLa cells. PLoS One (2012) 1.05
Nervous-tissue-specific elimination of microtubule-actin crosslinking factor 1a results in multiple developmental defects in the mouse brain. Mol Cell Neurosci (2010) 1.04
Microtubule stability, Golgi organization, and transport flux require dystonin-a2-MAP1B interaction. J Cell Biol (2012) 1.03
Adenomatous polyposis coli plays a key role, in vivo, in coordinating assembly of the neuronal nicotinic postsynaptic complex. Mol Cell Neurosci (2008) 1.02
Disease mutations in desmoplakin inhibit Cx43 membrane targeting mediated by desmoplakin-EB1 interactions. J Cell Biol (2014) 1.02
Plakins, a versatile family of cytolinkers: roles in skin integrity and in human diseases. J Invest Dermatol (2013) 1.01
Automated screening of microtubule growth dynamics identifies MARK2 as a regulator of leading edge microtubules downstream of Rac1 in migrating cells. PLoS One (2012) 1.01
Pleiotropic genes for metabolic syndrome and inflammation. Mol Genet Metab (2014) 1.01
Discovery of transcription factors and other candidate regulators of neural crest development. Dev Dyn (2008) 1.00
Laminin-based cell adhesion anchors microtubule plus ends to the epithelial cell basal cortex through LL5alpha/beta. J Cell Biol (2010) 0.99
Herpesvirus tegument protein pUL37 interacts with dystonin/BPAG1 to promote capsid transport on microtubules during egress. J Virol (2012) 0.97
GeneFriends: a human RNA-seq-based gene and transcript co-expression database. Nucleic Acids Res (2014) 0.97
The toxofilin-actin-PP2C complex of Toxoplasma: identification of interacting domains. Biochem J (2007) 0.95
MACF1 regulates the migration of pyramidal neurons via microtubule dynamics and GSK-3 signaling. Dev Biol (2014) 0.94
Characterization of G2L3 (GAS2-like 3), a new microtubule- and actin-binding protein related to spectraplakins. J Biol Chem (2011) 0.94
Invasive cells in animals and plants: searching for LECA machineries in later eukaryotic life. Biol Direct (2013) 0.92
Knockdown of microtubule actin crosslinking factor 1 inhibits cell proliferation in MC3T3-E1 osteoblastic cells. BMB Rep (2015) 0.91
Intermediate filament-associated cytolinker plectin 1c destabilizes microtubules in keratinocytes. Mol Biol Cell (2013) 0.90
VAB-10 spectraplakin acts in cell and nuclear migration in Caenorhabditis elegans. Development (2011) 0.90
The Gas2 family protein Pigs is a microtubule +TIP that affects cytoskeleton organisation. J Cell Sci (2015) 0.89
Essential and nonredundant roles for Diaphanous formins in cortical microtubule capture and directed cell migration. Mol Biol Cell (2014) 0.89
ELMO recruits actin cross-linking family 7 (ACF7) at the cell membrane for microtubule capture and stabilization of cellular protrusions. J Biol Chem (2012) 0.89
Cytoskeletal social networking in the growth cone: How +TIPs mediate microtubule-actin cross-linking to drive axon outgrowth and guidance. Cytoskeleton (Hoboken) (2016) 0.88
The kinetics of force-induced cell reorganization depend on microtubules and actin. Cytoskeleton (Hoboken) (2010) 0.88
Neuronal dystonin isoform 2 is a mediator of endoplasmic reticulum structure and function. Mol Biol Cell (2011) 0.88
Actin-microtubule coordination at growing microtubule ends. Nat Commun (2014) 0.88
Untethering the nuclear envelope and cytoskeleton: biologically distinct dystonias arising from a common cellular dysfunction. Int J Cell Biol (2012) 0.87
Characterization of mammalian Par 6 as a dual-location protein. Mol Cell Biol (2007) 0.86
GAS2-like proteins mediate communication between microtubules and actin through interactions with end-binding proteins. J Cell Sci (2014) 0.86
ACF7 is a hair-bundle antecedent, positioned to integrate cuticular plate actin and somatic tubulin. J Neurosci (2014) 0.86
Patronin/Shot Cortical Foci Assemble the Noncentrosomal Microtubule Array that Specifies the Drosophila Anterior-Posterior Axis. Dev Cell (2016) 0.86
Targeted inactivation of a developmentally regulated neural plectin isoform (plectin 1c) in mice leads to reduced motor nerve conduction velocity. J Biol Chem (2009) 0.86
The actin-microtubule cross-linking activity of Drosophila Short stop is regulated by intramolecular inhibition. Mol Biol Cell (2013) 0.86
DDA3 associates with microtubule plus ends and orchestrates microtubule dynamics and directional cell migration. Sci Rep (2013) 0.85
Microtubule guidance tested through controlled cell geometry. J Cell Sci (2012) 0.85
Talin-KANK1 interaction controls the recruitment of cortical microtubule stabilizing complexes to focal adhesions. Elife (2016) 0.85
An EB1-kinesin complex is sufficient to steer microtubule growth in vitro. Curr Biol (2014) 0.84
Microtubule Actin Cross-linking Factor 1 regulates cardiomyocyte microtubule distribution and adaptation to hemodynamic overload. PLoS One (2013) 0.84
Epiplakin is dispensable for skin barrier function and for integrity of keratin network cytoarchitecture in simple and stratified epithelia. Mol Cell Biol (2006) 0.84
Exome sequencing for bipolar disorder points to roles of de novo loss-of-function and protein-altering mutations. Mol Psychiatry (2016) 0.82
Kif4 interacts with EB1 and stabilizes microtubules downstream of Rho-mDia in migrating fibroblasts. PLoS One (2014) 0.82
Microtubule plus-end conformations and dynamics in the periphery of interphase mouse fibroblasts. Mol Biol Cell (2008) 0.82
Neurodegeneration and microtubule dynamics: death by a thousand cuts. Front Cell Neurosci (2015) 0.82
Microtubule-Actin Crosslinking Factor 1 Is Required for Dendritic Arborization and Axon Outgrowth in the Developing Brain. Mol Neurobiol (2015) 0.81
Partial depletion of gamma-actin suppresses microtubule dynamics. Cytoskeleton (Hoboken) (2013) 0.80
FAM123A binds to microtubules and inhibits the guanine nucleotide exchange factor ARHGEF2 to decrease actomyosin contractility. Sci Signal (2012) 0.80
Proto-Oncogenic Src Phosphorylates EB1 to Regulate the Microtubule-Focal Adhesion Crosstalk and Stimulate Cell Migration. Theranostics (2016) 0.78
Regulation of Focal Adhesion Dynamics and Cell Motility by the EB2 and Hax1 Protein Complex. J Biol Chem (2015) 0.78
Microtubule plus-end tracking proteins in neuronal development. Cell Mol Life Sci (2016) 0.77
Differential distribution of posttranslationally modified microtubules in osteoclasts. J Histochem Cytochem (2011) 0.77
Duplication in the microtubule-actin cross-linking factor 1 gene causes a novel neuromuscular condition. Sci Rep (2014) 0.76
Cell Fate Decision Making through Oriented Cell Division. J Dev Biol (2015) 0.76
Short stop mediates axonal compartmentalization of mucin-type core 1 glycans. Sci Rep (2017) 0.75
Ultraviolet B Inhibits Skin Wound Healing by Affecting Focal Adhesion Dynamics. Photochem Photobiol (2015) 0.75
Cortical dynamics during cell motility are regulated by CRL3(KLHL21) E3 ubiquitin ligase. Nat Commun (2016) 0.75
The spectraplakin short stop is an essential microtubule regulator involved in epithelial closure in Drosophila. J Cell Sci (2017) 0.75
Loss of MACF1 Abolishes Ciliogenesis and Disrupts Apicobasal Polarity Establishment in the Retina. Cell Rep (2016) 0.75
Nuclear positioning by actin cables and perinuclear actin: Special and general? Nucleus (2014) 0.75
Prenatal diagnosis of 1p34.3 interstitial microdeletion by aCGH in a fetus with jaw bone abnormalities. Mol Cytogenet (2016) 0.75
Nuclear positioning in the gonadal distal tip cells of C. elegans. Worm (2012) 0.75
Defining the epithelial stem cell niche in skin. Science (2003) 14.93
Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche. Cell (2004) 10.79
Epidermal homeostasis: a balancing act of stem cells in the skin. Nat Rev Mol Cell Biol (2009) 7.95
Asymmetric cell divisions promote stratification and differentiation of mammalian skin. Nature (2005) 6.67
Morphogenesis in skin is governed by discrete sets of differentially expressed microRNAs. Nat Genet (2006) 6.30
A skin microRNA promotes differentiation by repressing 'stemness'. Nature (2008) 5.66
Ezh2 orchestrates gene expression for the stepwise differentiation of tissue-specific stem cells. Cell (2009) 5.51
A two-step mechanism for stem cell activation during hair regeneration. Cell Stem Cell (2009) 5.40
Hair follicle stem cells are specified and function in early skin morphogenesis. Cell Stem Cell (2008) 5.02
Sticky business: orchestrating cellular signals at adherens junctions. Cell (2003) 4.91
Links between signal transduction, transcription and adhesion in epithelial bud development. Nature (2003) 4.88
Intercellular adhesion, signalling and the cytoskeleton. Nat Cell Biol (2002) 4.29
Molecular dissection of mesenchymal-epithelial interactions in the hair follicle. PLoS Biol (2005) 4.27
Dynamics between stem cells, niche, and progeny in the hair follicle. Cell (2011) 4.14
Epithelial stem cells: turning over new leaves. Cell (2007) 4.10
C-cadherin ectodomain structure and implications for cell adhesion mechanisms. Science (2002) 4.03
Actin cable dynamics and Rho/Rock orchestrate a polarized cytoskeletal architecture in the early steps of assembling a stratified epithelium. Dev Cell (2002) 4.01
Epidermal stem cells of the skin. Annu Rev Cell Dev Biol (2006) 3.92
DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration. Nature (2011) 3.90
Tcf3 governs stem cell features and represses cell fate determination in skin. Cell (2006) 3.88
NFATc1 balances quiescence and proliferation of skin stem cells. Cell (2008) 3.81
Blimp1 defines a progenitor population that governs cellular input to the sebaceous gland. Cell (2006) 3.79
Mammalian formin-1 participates in adherens junctions and polymerization of linear actin cables. Nat Cell Biol (2003) 3.77
Basal cells are a multipotent progenitor capable of renewing the bronchial epithelium. Am J Pathol (2004) 3.70
Defining the impact of beta-catenin/Tcf transactivation on epithelial stem cells. Genes Dev (2005) 3.67
Asymmetric cell divisions promote Notch-dependent epidermal differentiation. Nature (2011) 3.64
Interferon-γ links ultraviolet radiation to melanomagenesis in mice. Nature (2011) 3.56
Loss of TGFbeta signaling destabilizes homeostasis and promotes squamous cell carcinomas in stratified epithelia. Cancer Cell (2007) 3.55
Canonical notch signaling functions as a commitment switch in the epidermal lineage. Genes Dev (2006) 3.51
A role for skin gammadelta T cells in wound repair. Science (2002) 3.51
The inner nuclear membrane protein Sun1 mediates the anchorage of Nesprin-2 to the nuclear envelope. J Cell Sci (2005) 3.33
Loss of a quiescent niche but not follicle stem cells in the absence of bone morphogenetic protein signaling. Proc Natl Acad Sci U S A (2007) 3.16
In vivo differentiation potential of tracheal basal cells: evidence for multipotent and unipotent subpopulations. Am J Physiol Lung Cell Mol Physiol (2003) 3.08
Planar polarization in embryonic epidermis orchestrates global asymmetric morphogenesis of hair follicles. Nat Cell Biol (2008) 3.07
GATA-3: an unexpected regulator of cell lineage determination in skin. Genes Dev (2003) 2.97
ACF7 regulates cytoskeletal-focal adhesion dynamics and migration and has ATPase activity. Cell (2008) 2.94
Stem cells in the skin: waste not, Wnt not. Genes Dev (2003) 2.80
Genome-wide maps of histone modifications unwind in vivo chromatin states of the hair follicle lineage. Cell Stem Cell (2011) 2.80
Focal adhesion kinase modulates tension signaling to control actin and focal adhesion dynamics. J Cell Biol (2007) 2.79
Alpha-catenin: at the junction of intercellular adhesion and actin dynamics. Nat Rev Mol Cell Biol (2004) 2.79
Lhx2 maintains stem cell character in hair follicles. Science (2006) 2.78
Loss of kindlin-1, a human homolog of the Caenorhabditis elegans actin-extracellular-matrix linker protein UNC-112, causes Kindler syndrome. Am J Hum Genet (2003) 2.73
Catenins: keeping cells from getting their signals crossed. Dev Cell (2006) 2.70
Protection of the intestinal mucosa by intraepithelial gamma delta T cells. Proc Natl Acad Sci U S A (2002) 2.69
p120-catenin mediates inflammatory responses in the skin. Cell (2006) 2.66
DNA methylation dynamics during in vivo differentiation of blood and skin stem cells. Mol Cell (2012) 2.66
Defining BMP functions in the hair follicle by conditional ablation of BMP receptor IA. J Cell Biol (2003) 2.65
EZH1 and EZH2 cogovern histone H3K27 trimethylation and are essential for hair follicle homeostasis and wound repair. Genes Dev (2011) 2.63
The hair cycle. J Cell Sci (2006) 2.58
DGCR8-dependent microRNA biogenesis is essential for skin development. Proc Natl Acad Sci U S A (2008) 2.49
RNAi screens in mice identify physiological regulators of oncogenic growth. Nature (2013) 2.46
BMP signaling in dermal papilla cells is required for their hair follicle-inductive properties. Genes Dev (2008) 2.41
Skin stem cells orchestrate directional migration by regulating microtubule-ACF7 connections through GSK3β. Cell (2011) 2.36
Identification of stem cell populations in sweat glands and ducts reveals roles in homeostasis and wound repair. Cell (2012) 2.35
Enaptin, a giant actin-binding protein, is an element of the nuclear membrane and the actin cytoskeleton. Exp Cell Res (2004) 2.27
Tcf3: a transcriptional regulator of axis induction in the early embryo. Development (2003) 2.26
Stem cells of the skin epithelium. Proc Natl Acad Sci U S A (2003) 2.20
Desmoplakin: an unexpected regulator of microtubule organization in the epidermis. J Cell Biol (2007) 2.16
Lamin A/C-dependent localization of Nesprin-2, a giant scaffolder at the nuclear envelope. Mol Biol Cell (2005) 2.15
Differential regulation of midbrain dopaminergic neuron development by Wnt-1, Wnt-3a, and Wnt-5a. Proc Natl Acad Sci U S A (2003) 2.14
Tumor-initiating stem cells of squamous cell carcinomas and their control by TGF-β and integrin/focal adhesion kinase (FAK) signaling. Proc Natl Acad Sci U S A (2011) 2.13
Yes-associated protein (YAP) transcriptional coactivator functions in balancing growth and differentiation in skin. Proc Natl Acad Sci U S A (2011) 2.08
Tcf3 and Tcf4 are essential for long-term homeostasis of skin epithelia. Nat Genet (2009) 2.07
Epidermolysis bullosa simplex: a paradigm for disorders of tissue fragility. J Clin Invest (2009) 2.06
Rapid functional dissection of genetic networks via tissue-specific transduction and RNAi in mouse embryos. Nat Med (2010) 2.01
Paracrine TGF-β signaling counterbalances BMP-mediated repression in hair follicle stem cell activation. Cell Stem Cell (2012) 1.99
Conditional targeting of E-cadherin in skin: insights into hyperproliferative and degenerative responses. Proc Natl Acad Sci U S A (2004) 1.99
A family business: stem cell progeny join the niche to regulate homeostasis. Nat Rev Mol Cell Biol (2012) 1.91
Nesprin-2 Giant (NUANCE) maintains nuclear envelope architecture and composition in skin. J Cell Sci (2008) 1.86
A role for the primary cilium in Notch signaling and epidermal differentiation during skin development. Cell (2011) 1.83
Links between alpha-catenin, NF-kappaB, and squamous cell carcinoma in skin. Proc Natl Acad Sci U S A (2006) 1.77
Cyfip1 is a putative invasion suppressor in epithelial cancers. Cell (2009) 1.77
Delta6-desaturase (FADS2) deficiency unveils the role of omega3- and omega6-polyunsaturated fatty acids. EMBO J (2008) 1.72
Planar cell polarity protein Celsr1 regulates endothelial adherens junctions and directed cell rearrangements during valve morphogenesis. Dev Cell (2013) 1.70
A signaling pathway involving TGF-beta2 and snail in hair follicle morphogenesis. PLoS Biol (2004) 1.63
Isolation and culture of epithelial stem cells. Methods Mol Biol (2009) 1.63
Hedgehog signaling regulates the generation of ameloblast progenitors in the continuously growing mouse incisor. Development (2010) 1.55
Direct in vivo RNAi screen unveils myosin IIa as a tumor suppressor of squamous cell carcinomas. Science (2014) 1.53
Targeted disruption of the murine zyxin gene. Mol Cell Biol (2003) 1.51
The harmonies played by TGF-β in stem cell biology. Cell Stem Cell (2012) 1.47
Structure and transcription of the human m3 muscarinic receptor gene. Am J Respir Cell Mol Biol (2002) 1.47
Beta 1-integrins are required for hippocampal AMPA receptor-dependent synaptic transmission, synaptic plasticity, and working memory. J Neurosci (2006) 1.42
Loss of p120 catenin and links to mitotic alterations, inflammation, and skin cancer. Proc Natl Acad Sci U S A (2008) 1.40
AP-2alpha: a regulator of EGF receptor signaling and proliferation in skin epidermis. J Cell Biol (2006) 1.38
Developmental roles for Srf, cortical cytoskeleton and cell shape in epidermal spindle orientation. Nat Cell Biol (2011) 1.37
New insights into cadherin function in epidermal sheet formation and maintenance of tissue integrity. Proc Natl Acad Sci U S A (2008) 1.37
A role for alphabeta1 integrins in focal adhesion function and polarized cytoskeletal dynamics. Dev Cell (2003) 1.35
SOX9: a stem cell transcriptional regulator of secreted niche signaling factors. Genes Dev (2014) 1.34
Protein tyrosine kinase 6 negatively regulates growth and promotes enterocyte differentiation in the small intestine. Mol Cell Biol (2006) 1.33
Specific microRNAs are preferentially expressed by skin stem cells to balance self-renewal and early lineage commitment. Cell Stem Cell (2011) 1.33
AP-2 factors act in concert with Notch to orchestrate terminal differentiation in skin epidermis. J Cell Biol (2008) 1.33
What does the concept of the stem cell niche really mean today? BMC Biol (2012) 1.32
p63: revving up epithelial stem-cell potential. Nat Cell Biol (2007) 1.32
An RNA interference screen uncovers a new molecule in stem cell self-renewal and long-term regeneration. Nature (2012) 1.32
NFIB is a governor of epithelial-melanocyte stem cell behaviour in a shared niche. Nature (2013) 1.29
Mitotic internalization of planar cell polarity proteins preserves tissue polarity. Nat Cell Biol (2011) 1.28
The LEF1/beta -catenin complex activates movo1, a mouse homolog of Drosophila ovo required for epidermal appendage differentiation. Proc Natl Acad Sci U S A (2002) 1.27
The LINC-less granulocyte nucleus. Eur J Cell Biol (2008) 1.26