The male minor transplantation antigen preferentially activates recipient CD4+ T cells through the indirect presentation pathway in vivo.

PubWeight™: 1.09‹?› | Rank: Top 10%

🔗 View Article (PMID 14662851)

Published in J Immunol on December 15, 2003

Authors

Yifa Chen1, Yilmaz Demir, Anna Valujskikh, Peter S Heeger

Author Affiliations

1: Department of Immunology and The Glickman Urologic Institute, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA.

Articles citing this

Langerhans cells are not required for efficient skin graft rejection. J Invest Dermatol (2008) 2.41

Constraints in antigen presentation severely restrict T cell recognition of the allogeneic fetus. J Clin Invest (2007) 1.75

Decay accelerating factor can control T cell differentiation into IFN-gamma-producing effector cells via regulating local C5a-induced IL-12 production. J Immunol (2007) 1.59

Pregnancy induces a fetal antigen-specific maternal T regulatory cell response that contributes to tolerance. Proc Natl Acad Sci U S A (2010) 1.26

Autoantibodies to vimentin cause accelerated rejection of cardiac allografts. Am J Pathol (2007) 1.12

Donor dendritic cell-derived exosomes promote allograft-targeting immune response. J Clin Invest (2016) 1.03

Dendritic cell therapies in transplantation revisited: deletion of recipient DCs deters the effect of therapeutic DCs. Am J Transplant (2012) 1.01

Anticardiac myosin immunity and chronic allograft vasculopathy in heart transplant recipients. J Immunol (2011) 0.96

Genetic or pharmaceutical blockade of phosphoinositide 3-kinase p110δ prevents chronic rejection of heart allografts. PLoS One (2012) 0.94

Gamma c cytokines condition the progressive differentiation of CD4+ T cells. Proc Natl Acad Sci U S A (2007) 0.84

IFN-γ production by memory helper T cells is required for CD40-independent alloantibody responses. J Immunol (2014) 0.83

Mixed chimerism and split tolerance: mechanisms and clinical correlations. Chimerism (2012) 0.83

Sculpting MHC class II-restricted self and non-self peptidome by the class I Ag-processing machinery and its impact on Th-cell responses. Eur J Immunol (2013) 0.80

Proteasomes, TAP, and endoplasmic reticulum-associated aminopeptidase associated with antigen processing control CD4+ Th cell responses by regulating indirect presentation of MHC class II-restricted cytoplasmic antigens. J Immunol (2011) 0.79

The cholinergic anti-inflammatory pathway delays TLR-induced skin allograft rejection in mice: cholinergic pathway modulates alloreactivity. PLoS One (2013) 0.76

Obesity-Induced Metabolic Stress Leads to Biased Effector Memory CD4(+) T Cell Differentiation via PI3K p110δ-Akt-Mediated Signals. Cell Metab (2017) 0.75

Antigen Presentation in Transplantation. Trends Immunol (2016) 0.75

Articles by these authors

Urinary-cell mRNA profile and acute cellular rejection in kidney allografts. N Engl J Med (2013) 7.40

Locally produced complement fragments C5a and C3a provide both costimulatory and survival signals to naive CD4+ T cells. Immunity (2008) 3.36

Locally produced C5a binds to T cell-expressed C5aR to enhance effector T-cell expansion by limiting antigen-induced apoptosis. Blood (2008) 2.91

Decay-accelerating factor modulates induction of T cell immunity. J Exp Med (2005) 2.34

Cross-primed CD8(+) T cells mediate graft rejection via a distinct effector pathway. Nat Immunol (2002) 2.25

Primed allospecific T cells prevent the effects of costimulatory blockade on prolonged cardiac allograft survival in mice. Am J Transplant (2002) 2.18

Donor Toll-like receptor 4 contributes to ischemia and reperfusion injury following human kidney transplantation. Proc Natl Acad Sci U S A (2009) 1.95

Pretransplant CSF-1 therapy expands recipient macrophages and ameliorates GVHD after allogeneic hematopoietic cell transplantation. J Exp Med (2011) 1.78

T cells primed by Leishmania major infection cross-react with alloantigens and alter the course of allograft rejection. J Immunol (2002) 1.73

Pre-transplant IFN-gamma ELISPOTs are associated with post-transplant renal function in African American renal transplant recipients. Am J Transplant (2005) 1.60

Decay accelerating factor can control T cell differentiation into IFN-gamma-producing effector cells via regulating local C5a-induced IL-12 production. J Immunol (2007) 1.59

Immune cell-derived c3 is required for autoimmune diabetes induced by multiple low doses of streptozotocin. Diabetes (2010) 1.57

CD8 T cells can reject major histocompatibility complex class I-deficient skin allografts. Am J Transplant (2004) 1.57

Pretransplant cellular alloimmunity as assessed by a panel of reactive T cells assay correlates with acute renal graft rejection. Transplantation (2007) 1.50

Signaling through C5a receptor and C3a receptor diminishes function of murine natural regulatory T cells. J Exp Med (2013) 1.48

Enzyme linked immunosorbent spot (ELISPOT) assay for interferon-gamma independently predicts renal function in kidney transplant recipients. Am J Transplant (2003) 1.47

Biosensors from conjugated polyelectrolyte complexes. Proc Natl Acad Sci U S A (2001) 1.46

IFN-gamma and IL-17 production in experimental autoimmune encephalomyelitis depends on local APC-T cell complement production. J Immunol (2008) 1.45

In vivo helper functions of alloreactive memory CD4+ T cells remain intact despite donor-specific transfusion and anti-CD40 ligand therapy. J Immunol (2004) 1.45

Evolution of the enzyme-linked immunosorbent spot assay for post-transplant alloreactivity as a potentially useful immune monitoring tool. Am J Transplant (2002) 1.38

Panel of reactive T cells as a measurement of primed cellular alloimmunity in kidney transplant candidates. J Am Soc Nephrol (2005) 1.37

Alloreactive T cell responses and acute rejection of single class II MHC-disparate heart allografts are under strict regulation by CD4+ CD25+ T cells. J Immunol (2005) 1.32

Donor deficiency of decay-accelerating factor accelerates murine T cell-mediated cardiac allograft rejection. J Immunol (2008) 1.28

Lymphoid sequestration of alloreactive memory CD4 T cells promotes cardiac allograft survival. J Immunol (2006) 1.23

Alloreactivity in renal transplant recipients with and without chronic allograft nephropathy. J Am Soc Nephrol (2004) 1.22

HIV long-term non-progressors maintain brisk CD8 T cell responses to other viral antigens. AIDS (2002) 1.15

Cutting edge: Receptors for C3a and C5a modulate stability of alloantigen-reactive induced regulatory T cells. J Immunol (2013) 1.13

Preferential benefit of antibody induction therapy in kidney recipients with high pretransplant frequencies of donor-reactive interferon-gamma enzyme-linked immunosorbent spots. Transplantation (2008) 1.11

Antigen-presenting cell-derived complement modulates graft-versus-host disease. J Clin Invest (2012) 1.09

TLR ligand-dependent activation of naive CD4 T cells by plasmacytoid dendritic cells is impaired in hepatitis C virus infection. J Immunol (2007) 1.08

Effects of T cell frequency and graft size on transplant outcome in mice. J Immunol (2004) 1.05

Effects of influenza immunization on humoral and cellular alloreactivity in humans. Transplantation (2010) 1.02

Modulation of tissue-specific immune response to cardiac myosin can prolong survival of allogeneic heart transplants. J Immunol (2002) 0.99

Hemodialysis vintage, black ethnicity, and pretransplantation antidonor cellular immunity in kidney transplant recipients. J Am Soc Nephrol (2007) 0.99

Interleukin-17 promotes early allograft inflammation. Am J Pathol (2010) 0.97

Graft-derived complement as a mediator of transplant injury. Curr Opin Immunol (2007) 0.97

Anticardiac myosin immunity and chronic allograft vasculopathy in heart transplant recipients. J Immunol (2011) 0.96

Complement regulation of T cell immunity. Immunol Res (2012) 0.95

Donor factors influencing graft outcomes in live donor kidney transplantation. Transplantation (2007) 0.94

Complement regulates CD4 T-cell help to CD8 T cells required for murine allograft rejection. Am J Pathol (2011) 0.93

Complement gene expression in human cardiac allograft biopsies as a correlate of histologic grade of injury. Transplantation (2008) 0.93

The relative contribution of direct and indirect antigen recognition pathways to the alloresponse and graft rejection depends upon the nature of the transplant. Hum Immunol (2002) 0.93

Novel aspects of complement in kidney injury. Kidney Int (2009) 0.92

Antibodies reactive to non-HLA antigens in transplant glomerulopathy. J Am Soc Nephrol (2011) 0.91

T-cell immune monitoring in organ transplantation. Curr Opin Organ Transplant (2008) 0.91

Targeting complement component 5a promotes vascular integrity and limits airway remodeling. Proc Natl Acad Sci U S A (2013) 0.90

Mouse endothelial cells cross-present lymphocyte-derived antigen on class I MHC via a TAP1- and proteasome-dependent pathway. J Immunol (2005) 0.90

Emerging roles of endothelial cells in transplant rejection. Curr Opin Immunol (2003) 0.90

Complement as a multifaceted modulator of kidney transplant injury. J Clin Invest (2014) 0.89

Comprehensive determinant mapping of the hepatitis C-specific CD8 cell repertoire reveals unpredicted immune hierarchy. Clin Immunol (2002) 0.89

Heterogeneous alterations in human alloimmunity associated with immunization. Transplantation (2005) 0.89

Antibody-mediated rejection: emergence of animal models to answer clinical questions. Am J Transplant (2010) 0.87

Development of autoimmunity after skin graft rejection via an indirect alloresponse. Transplantation (2002) 0.87

Analysis of immune markers in human cardiac allograft recipients and association with coronary artery vasculopathy. J Heart Lung Transplant (2005) 0.86

Antigen location contributes to the pathological features of a transplanted heart graft. Am J Pathol (2004) 0.85

Unexpected role for MHC II-peptide complexes in shaping CD8 T-cell expansion and differentiation in vivo. Proc Natl Acad Sci U S A (2012) 0.85

Effects of preexisting autoimmunity on heart graft prolongation after donor-specific transfusion and anti-CD154. Transplantation (2014) 0.84

CD8 T cells specific for a donor-derived, self-restricted transplant antigen are nonpathogenic bystanders after vascularized heart transplantation in mice. J Immunol (2006) 0.84

Effects of green tea polyphenols on murine transplant-reactive T cell immunity. Clin Immunol (2004) 0.82

Effects of cellular sensitization and donor age on acute rejection and graft function after deceased-donor kidney transplantation. Transplantation (2013) 0.82

Effect of high-dose intravenous immunoglobulin on anti-HLA antibodies in sensitized kidney transplant candidates. Clin Transplant (2012) 0.82

Complement regulation of T-cell alloimmunity. Semin Nephrol (2013) 0.81

Immunologic monitoring in transplantation revisited. Curr Opin Organ Transplant (2012) 0.81

Locally produced and activated complement as a mediator of alloreactive T cells. Front Biosci (Schol Ed) (2009) 0.81

Effects of complement activation on allograft injury. Curr Opin Organ Transplant (2015) 0.79

Complement regulation of T-cell alloimmunity. Curr Opin Organ Transplant (2011) 0.78

Gazing into a crystal ball to predict kidney transplant outcome. J Clin Invest (2010) 0.77

B cells in cardiac transplants: from clinical questions to experimental models. Semin Immunol (2011) 0.77

Proteomic portrayal of transplant pathologies. J Am Soc Nephrol (2009) 0.77

Cardiac allograft rejection in the absence of macrophage migration inhibitory factor. Transplantation (2003) 0.76

Transplantation: Complementing donor-specific antibody testing. Nat Rev Nephrol (2013) 0.75

Sequestration and suppression of anti-HLA antibodies by a failed kidney allograft. Clin J Am Soc Nephrol (2012) 0.75

Effect of Absent Immune Cell Expression of Vitamin D Receptor on Cardiac Allograft Survival in Mice. Transplantation (2015) 0.75

T-cell immune monitoring in organ transplantation. Transplantation (2009) 0.75

Immune monitoring in kidney transplant recipients revisited. J Am Soc Nephrol (2002) 0.75

Mechanisms of antibody-mediated acute and chronic rejection of kidney allografts. Curr Opin Organ Transplant (2016) 0.75

Correction: The soluble pattern recognition receptor PTX3 links humoral innate and adaptive immune responses by helping marginal zone B cells. J Exp Med (2017) 0.75

Corrigendum. Complement as a multifaceted modulator of kidney transplant injury. J Clin Invest (2015) 0.75

Role of Circulating microRNAs in the Immunopathogenesis of Rejection Following Pediatric Lung Transplantation. Transplantation (2016) 0.75