Cardiovascular mortality and long-term exposure to particulate air pollution: epidemiological evidence of general pathophysiological pathways of disease.

PubWeight™: 12.78‹?› | Rank: Top 0.1% | All-Time Top 10000

🔗 View Article (PMID 14676145)

Published in Circulation on December 15, 2003

Authors

C Arden Pope1, Richard T Burnett, George D Thurston, Michael J Thun, Eugenia E Calle, Daniel Krewski, John J Godleski

Author Affiliations

1: Brigham Young University, 130 FOB, Provo, UT 84602-2363, USA. cap3@email.byu.edu

Associated clinical trials:

World Trade Center (WTC) RENAL | NCT02246101

Articles citing this

(truncated to the top 100)

A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet (2012) 50.94

Fine particulate air pollution and hospital admission for cardiovascular and respiratory diseases. JAMA (2006) 13.43

Reduction in fine particulate air pollution and mortality: Extended follow-up of the Harvard Six Cities study. Am J Respir Crit Care Med (2006) 10.44

Fine-particulate air pollution and life expectancy in the United States. N Engl J Med (2009) 8.36

Ambient air pollution and atherosclerosis in Los Angeles. Environ Health Perspect (2005) 6.19

Ambient air pollution exaggerates adipose inflammation and insulin resistance in a mouse model of diet-induced obesity. Circulation (2009) 4.71

Drug delivery and nanoparticles:applications and hazards. Int J Nanomedicine (2008) 4.59

Long-term air pollution exposure and cardio- respiratory mortality: a review. Environ Health (2013) 4.01

Effect of air pollution control on life expectancy in the United States: an analysis of 545 U.S. counties for the period from 2000 to 2007. Epidemiology (2013) 3.93

Long-term effects of traffic-related air pollution on mortality in a Dutch cohort (NLCS-AIR study). Environ Health Perspect (2008) 3.70

Cardiovascular effects of nickel in ambient air. Environ Health Perspect (2006) 3.69

Global association of air pollution and heart failure: a systematic review and meta-analysis. Lancet (2013) 3.57

The potential risks of nanomaterials: a review carried out for ECETOC. Part Fibre Toxicol (2006) 3.56

Chronic fine and coarse particulate exposure, mortality, and coronary heart disease in the Nurses' Health Study. Environ Health Perspect (2009) 3.45

Risk of nonaccidental and cardiovascular mortality in relation to long-term exposure to low concentrations of fine particulate matter: a Canadian national-level cohort study. Environ Health Perspect (2012) 3.39

Chronic exposure to fine particles and mortality: an extended follow-up of the Harvard Six Cities study from 1974 to 2009. Environ Health Perspect (2012) 3.38

Lung cancer and cardiovascular disease mortality associated with ambient air pollution and cigarette smoke: shape of the exposure-response relationships. Environ Health Perspect (2011) 3.36

Ambient particulate pollutants in the ultrafine range promote early atherosclerosis and systemic oxidative stress. Circ Res (2008) 3.26

Traffic-related air pollution and incident type 2 diabetes: results from the SALIA cohort study. Environ Health Perspect (2010) 3.23

The effect of particulate air pollution on emergency admissions for myocardial infarction: a multicity case-crossover analysis. Environ Health Perspect (2005) 3.19

Acute blood pressure responses in healthy adults during controlled air pollution exposures. Environ Health Perspect (2005) 3.14

Social and physical environments and disparities in risk for cardiovascular disease: the healthy environments partnership conceptual model. Environ Health Perspect (2005) 3.08

Adverse cardiovascular effects of air pollution. Nat Clin Pract Cardiovasc Med (2008) 3.00

Clearing the air: a review of the effects of particulate matter air pollution on human health. J Med Toxicol (2012) 2.83

Mind the gap. Environ Health Perspect (2010) 2.73

Long-term exposure to constituents of fine particulate air pollution and mortality: results from the California Teachers Study. Environ Health Perspect (2009) 2.72

Near-highway pollutants in motor vehicle exhaust: a review of epidemiologic evidence of cardiac and pulmonary health risks. Environ Health (2007) 2.58

Potential role of ultrafine particles in associations between airborne particle mass and cardiovascular health. Environ Health Perspect (2005) 2.57

GIS approaches for the estimation of residential-level ambient PM concentrations. Environ Health Perspect (2006) 2.53

Spatio-temporal modeling of chronic PM10 exposure for the Nurses' Health Study. Atmos Environ (1994) (2008) 2.51

Systematic evaluation of environmental factors: persistent pollutants and nutrients correlated with serum lipid levels. Int J Epidemiol (2012) 2.42

Fine particle sources and cardiorespiratory morbidity: an application of chemical mass balance and factor analytical source-apportionment methods. Environ Health Perspect (2008) 2.39

Predicting chronic fine and coarse particulate exposures using spatiotemporal models for the Northeastern and Midwestern United States. Environ Health Perspect (2008) 2.32

Long term exposure to ambient air pollution and incidence of acute coronary events: prospective cohort study and meta-analysis in 11 European cohorts from the ESCAPE Project. BMJ (2014) 2.30

Indoor air pollution and blood pressure in adult women living in rural China. Environ Health Perspect (2011) 2.25

Long-term exposure to urban air pollution and mortality in a cohort of more than a million adults in Rome. Environ Health Perspect (2013) 2.24

Exposures to airborne particulate matter and adverse perinatal outcomes: a biologically plausible mechanistic framework for exploring potential effect modification by nutrition. Environ Health Perspect (2006) 2.21

Long-term exposure to air pollution and cardiorespiratory disease in the California teachers study cohort. Am J Respir Crit Care Med (2011) 2.21

A case-control analysis of exposure to traffic and acute myocardial infarction. Environ Health Perspect (2007) 2.18

The association between fatal coronary heart disease and ambient particulate air pollution: Are females at greater risk? Environ Health Perspect (2005) 2.12

Induction of inflammation in vascular endothelial cells by metal oxide nanoparticles: effect of particle composition. Environ Health Perspect (2006) 2.01

Health impacts of the built environment: within-urban variability in physical inactivity, air pollution, and ischemic heart disease mortality. Environ Health Perspect (2011) 1.97

Short term impact of smoke-free legislation in England: retrospective analysis of hospital admissions for myocardial infarction. BMJ (2010) 1.95

Chronic particulate exposure, mortality, and coronary heart disease in the nurses' health study. Am J Epidemiol (2008) 1.91

Acute exposure to air pollution triggers atrial fibrillation. J Am Coll Cardiol (2013) 1.90

Effect of early particulate air pollution exposure on obesity in mice: role of p47phox. Arterioscler Thromb Vasc Biol (2010) 1.88

A cohort study of traffic-related air pollution and mortality in Toronto, Ontario, Canada. Environ Health Perspect (2009) 1.77

Health effects of particulate air pollution. Ann Epidemiol (2009) 1.72

Fast inverse distance weighting-based spatiotemporal interpolation: a web-based application of interpolating daily fine particulate matter PM2:5 in the contiguous U.S. using parallel programming and k-d tree. Int J Environ Res Public Health (2014) 1.70

Long-term exposure to traffic-related air pollution and the risk of coronary heart disease hospitalization and mortality. Environ Health Perspect (2010) 1.68

Cardiovascular effects of ambient particulate air pollution exposure. Circulation (2010) 1.67

Long-term exposure to ambient fine particulate pollution induces insulin resistance and mitochondrial alteration in adipose tissue. Toxicol Sci (2011) 1.65

Nanoparticles: health effects--pros and cons. Environ Health Perspect (2006) 1.63

Black carbon exposure, oxidative stress genes, and blood pressure in a repeated-measures study. Environ Health Perspect (2009) 1.59

Temporal relationship between air pollutants and hospital admissions for chronic obstructive pulmonary disease in Hong Kong. Thorax (2007) 1.59

Air Pollution and the microvasculature: a cross-sectional assessment of in vivo retinal images in the population-based multi-ethnic study of atherosclerosis (MESA). PLoS Med (2010) 1.59

Fine particulate air pollution and the progression of carotid intima-medial thickness: a prospective cohort study from the multi-ethnic study of atherosclerosis and air pollution. PLoS Med (2013) 1.58

Long-term associations of outdoor air pollution with mortality in Great Britain. Thorax (2007) 1.57

Cardiovascular effects of pulmonary exposure to single-wall carbon nanotubes. Environ Health Perspect (2006) 1.57

Ambient particulate air pollution and cardiac arrhythmia in a panel of older adults in Steubenville, Ohio. Occup Environ Med (2006) 1.56

Particulate matter and atherosclerosis: role of particle size, composition and oxidative stress. Part Fibre Toxicol (2009) 1.55

Exposure to diesel exhaust induces changes in EEG in human volunteers. Part Fibre Toxicol (2008) 1.54

Work, obesity, and occupational safety and health. Am J Public Health (2007) 1.53

Particulate air pollution, progression, and survival after myocardial infarction. Environ Health Perspect (2007) 1.52

Chronic obstructive pulmonary disease as an independent risk factor for cardiovascular morbidity. Int J Chron Obstruct Pulmon Dis (2009) 1.52

Prospective analysis of traffic exposure as a risk factor for incident coronary heart disease: the Atherosclerosis Risk in Communities (ARIC) study. Environ Health Perspect (2008) 1.51

Three measures of forest fire smoke exposure and their associations with respiratory and cardiovascular health outcomes in a population-based cohort. Environ Health Perspect (2011) 1.51

A hybrid approach to estimating national scale spatiotemporal variability of PM2.5 in the contiguous United States. Environ Sci Technol (2013) 1.51

Induction of proinflammatory cytokines and C-reactive protein in human macrophage cell line U937 exposed to air pollution particulates. Environ Health Perspect (2005) 1.50

Mortality associations with long-term exposure to outdoor air pollution in a national English cohort. Am J Respir Crit Care Med (2013) 1.50

Simulating and evaluating local interventions to improve cardiovascular health. Prev Chronic Dis (2009) 1.49

Residential Proximity to Major Roadways Is Associated With Increased Levels of AC133+ Circulating Angiogenic Cells. Arterioscler Thromb Vasc Biol (2015) 1.48

Air-pollutant chemicals and oxidized lipids exhibit genome-wide synergistic effects on endothelial cells. Genome Biol (2007) 1.46

Nitrogen dioxide levels estimated from land use regression models several years apart and association with mortality in a large cohort study. Environ Health (2012) 1.46

Association of heart rate variability in taxi drivers with marked changes in particulate air pollution in Beijing in 2008. Environ Health Perspect (2010) 1.45

Ozone, Fine Particulate Matter, and Chronic Lower Respiratory Disease Mortality in the United States. Am J Respir Crit Care Med (2015) 1.45

Inhalation of ultrafine particles alters blood leukocyte expression of adhesion molecules in humans. Environ Health Perspect (2006) 1.44

Heart rate variability in association with frequent use of household sprays and scented products in SAPALDIA. Environ Health Perspect (2012) 1.42

Apheis: Health impact assessment of long-term exposure to PM(2.5) in 23 European cities. Eur J Epidemiol (2006) 1.41

Particulate air pollution and survival in a COPD cohort. Environ Health (2008) 1.41

Exposure to traffic and left ventricular mass and function: the Multi-Ethnic Study of Atherosclerosis. Am J Respir Crit Care Med (2009) 1.41

Ultrafine particle deposition in subjects with asthma. Environ Health Perspect (2004) 1.40

Reviewing the environmental and human health knowledge base of carbon nanotubes. Environ Health Perspect (2007) 1.40

Can we identify sources of fine particles responsible for exercise-induced ischemia on days with elevated air pollution? The ULTRA study. Environ Health Perspect (2006) 1.38

Vehicular emissions induce vascular MMP-9 expression and activity associated with endothelin-1-mediated pathways. Arterioscler Thromb Vasc Biol (2009) 1.38

Mitochondrial complex III-generated oxidants activate ASK1 and JNK to induce alveolar epithelial cell death following exposure to particulate matter air pollution. J Biol Chem (2008) 1.37

An epidemiological appraisal of the association between heart rate variability and particulate air pollution: a meta-analysis. Heart (2012) 1.35

Long-term inhalation exposure to nickel nanoparticles exacerbated atherosclerosis in a susceptible mouse model. Environ Health Perspect (2010) 1.34

Particulate matter exposures, mortality, and cardiovascular disease in the health professionals follow-up study. Environ Health Perspect (2011) 1.31

Long-term fine particulate matter exposure and mortality from diabetes in Canada. Diabetes Care (2013) 1.29

Long-term ambient multipollutant exposures and mortality. Am J Respir Crit Care Med (2010) 1.29

Conceptual model of comprehensive research metrics for improved human health and environment. Environ Health Perspect (2008) 1.29

Environmental inequality and circulatory disease mortality gradients. J Epidemiol Community Health (2005) 1.28

Traffic-related particles are associated with elevated homocysteine: the VA normative aging study. Am J Respir Crit Care Med (2008) 1.27

Nanoparticle inhalation impairs endothelium-dependent vasodilation in subepicardial arterioles. J Toxicol Environ Health A (2009) 1.27

Oxidative stress and inflammation response after nanoparticle exposure: differences between human lung cell monocultures and an advanced three-dimensional model of the human epithelial airways. J R Soc Interface (2009) 1.26

A community participatory study of cardiovascular health and exposure to near-highway air pollution: study design and methods. Rev Environ Health (2013) 1.26

Traffic-related air pollution and QT interval: modification by diabetes, obesity, and oxidative stress gene polymorphisms in the normative aging study. Environ Health Perspect (2010) 1.25

Cytokine release from alveolar macrophages exposed to ambient particulate matter: heterogeneity in relation to size, city and season. Part Fibre Toxicol (2005) 1.25

Translocation of particles and inflammatory responses after exposure to fine particles and nanoparticles in an epithelial airway model. Part Fibre Toxicol (2007) 1.25

Articles by these authors

Cancer statistics, 2008. CA Cancer J Clin (2008) 86.74

Cancer statistics, 2009. CA Cancer J Clin (2009) 83.57

Cancer statistics, 2007. CA Cancer J Clin (2007) 53.49

A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet (2012) 50.94

Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet (2012) 41.47

Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults. N Engl J Med (2003) 35.39

Cancer statistics, 2006. CA Cancer J Clin (2006) 30.71

Lung cancer, cardiopulmonary mortality, and long-term exposure to fine particulate air pollution. JAMA (2002) 28.72

Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet (2012) 26.95

Cancer statistics, 2005. CA Cancer J Clin (2005) 25.65

A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer. Nat Genet (2007) 22.96

Genome-wide association study of prostate cancer identifies a second risk locus at 8q24. Nat Genet (2007) 21.18

Multiple loci identified in a genome-wide association study of prostate cancer. Nat Genet (2008) 17.65

Cancer statistics, 2004. CA Cancer J Clin (2004) 15.72

Cancer statistics, 2003. CA Cancer J Clin (2003) 13.46

Body-mass index and mortality among 1.46 million white adults. N Engl J Med (2010) 13.34

The state of US health, 1990-2010: burden of diseases, injuries, and risk factors. JAMA (2013) 10.43

Spatial analysis of air pollution and mortality in Los Angeles. Epidemiology (2005) 8.64

A multistage genome-wide association study in breast cancer identifies two new risk alleles at 1p11.2 and 14q24.1 (RAD51L1). Nat Genet (2009) 8.39

Annual report to the nation on the status of cancer, 1975-2005, featuring trends in lung cancer, tobacco use, and tobacco control. J Natl Cancer Inst (2008) 8.14

Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks in 188 countries, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet (2015) 7.99

Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2. Nat Genet (2009) 7.30

Annual report to the nation on the status of cancer, 1975-2000, featuring the uses of surveillance data for cancer prevention and control. J Natl Cancer Inst (2003) 7.06

Long-term ozone exposure and mortality. N Engl J Med (2009) 6.90

Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries, 1990-2013: quantifying the epidemiological transition. Lancet (2015) 6.13

Annual report to the nation on the status of cancer, 1973-1999, featuring implications of age and aging on U.S. cancer burden. Cancer (2002) 6.08

Extended follow-up and spatial analysis of the American Cancer Society study linking particulate air pollution and mortality. Res Rep Health Eff Inst (2009) 5.92

Performance of common genetic variants in breast-cancer risk models. N Engl J Med (2010) 5.79

Smoking and mortality--beyond established causes. N Engl J Med (2015) 5.54

Diabetes mellitus as a predictor of cancer mortality in a large cohort of US adults. Am J Epidemiol (2004) 5.29

The American Cancer Society Cancer Prevention Study II Nutrition Cohort: rationale, study design, and baseline characteristics. Cancer (2002) 4.88

Cardiovascular mortality and exposure to airborne fine particulate matter and cigarette smoke: shape of the exposure-response relationship. Circulation (2009) 4.84

Cancer mortality in the United States by education level and race. J Natl Cancer Inst (2007) 4.77

American Cancer Society Guidelines on Nutrition and Physical Activity for cancer prevention: reducing the risk of cancer with healthy food choices and physical activity. CA Cancer J Clin (2006) 4.69

Exposure assessment for estimation of the global burden of disease attributable to outdoor air pollution. Environ Sci Technol (2012) 4.44

The effect of concurvity in generalized additive models linking mortality to ambient particulate matter. Epidemiology (2003) 4.22

Two large prospective studies of mortality among men who use snuff or chewing tobacco (United States). Cancer Causes Control (2005) 3.88

Identification of a new prostate cancer susceptibility locus on chromosome 8q24. Nat Genet (2009) 3.76

Leisure time spent sitting in relation to total mortality in a prospective cohort of US adults. Am J Epidemiol (2010) 3.64

Nonsteroidal antiinflammatory drug use and the risk for Parkinson's disease. Ann Neurol (2005) 3.58

Role of smoking in global and regional cardiovascular mortality. Circulation (2005) 3.57

Risk of nonaccidental and cardiovascular mortality in relation to long-term exposure to low concentrations of fine particulate matter: a Canadian national-level cohort study. Environ Health Perspect (2012) 3.39

Benefits of smoking cessation for longevity. Am J Public Health (2002) 3.38

Lung cancer and cardiovascular disease mortality associated with ambient air pollution and cigarette smoke: shape of the exposure-response relationships. Environ Health Perspect (2011) 3.36

Recent trends in breast cancer incidence rates by age and tumor characteristics among U.S. women. Breast Cancer Res (2007) 3.23

Public health benefits of strategies to reduce greenhouse-gas emissions: health implications of short-lived greenhouse pollutants. Lancet (2009) 3.22

Meat consumption and risk of colorectal cancer. JAMA (2005) 3.15

A common 8q24 variant in prostate and breast cancer from a large nested case-control study. Cancer Res (2007) 3.08

Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study. Nat Genet (2011) 3.07

The landscape of recombination in African Americans. Nature (2011) 3.06

Under-use of smoking-cessation treatments: results from the National Health Interview Survey, 2000. Am J Prev Med (2005) 3.02

Obesity may increase the incidence of asthma in women but not in men: longitudinal observations from the Canadian National Population Health Surveys. Am J Epidemiol (2002) 3.01

Obesity and cancer. Oncogene (2004) 3.01

Genome-wide association study of renal cell carcinoma identifies two susceptibility loci on 2p21 and 11q13.3. Nat Genet (2010) 2.96

A large cohort study of long-term daily use of adult-strength aspirin and cancer incidence. J Natl Cancer Inst (2007) 2.95

Preventing cancer, cardiovascular disease, and diabetes: a common agenda for the American Cancer Society, the American Diabetes Association, and the American Heart Association. Circulation (2004) 2.91

Pesticide exposure and risk for Parkinson's disease. Ann Neurol (2006) 2.89

Waist circumference and all-cause mortality in a large US cohort. Arch Intern Med (2010) 2.88

Meta-analysis of time-series studies of air pollution and mortality: effects of gases and particles and the influence of cause of death, age, and season. J Air Waste Manag Assoc (2002) 2.81

Lung cancer in never smokers: clinical epidemiology and environmental risk factors. Clin Cancer Res (2009) 2.77

It's about time: a comparison of Canadian and American time-activity patterns. J Expo Anal Environ Epidemiol (2002) 2.75

Genome-wide association study of prostate cancer in men of African ancestry identifies a susceptibility locus at 17q21. Nat Genet (2011) 2.70

Lung cancer death rates in lifelong nonsmokers. J Natl Cancer Inst (2006) 2.66

Long-term ambient fine particulate matter air pollution and lung cancer in a large cohort of never-smokers. Am J Respir Crit Care Med (2011) 2.64

Role of smoking in global and regional cancer epidemiology: current patterns and data needs. Int J Cancer (2005) 2.62

Nicotinic receptor gene variants influence susceptibility to heavy smoking. Cancer Epidemiol Biomarkers Prev (2008) 2.58

Association between gaseous ambient air pollutants and adverse pregnancy outcomes in Vancouver, Canada. Environ Health Perspect (2003) 2.55