CD4+ CD25+ CD62+ T-regulatory cell subset has optimal suppressive and proliferative potential.

PubWeight™: 1.39‹?› | Rank: Top 5%

🔗 View Article (PMID 14678036)

Published in Am J Transplant on January 01, 2004

Authors

Shuang Fu1, Adam C Yopp, Xia Mao, Dongmei Chen, Nan Zhang, Dan Chen, Minwei Mao, Yaozhong Ding, Jonathan S Bromberg

Author Affiliations

1: Carl C. Icahn Center for Gene Therapy and Molecular Medicine, Mount Sinai School of Medicine, New York, NY, USA.

Articles citing this

Anti-TNF-alpha therapy induces a distinct regulatory T cell population in patients with rheumatoid arthritis via TGF-beta. J Exp Med (2007) 2.47

Epigenetic mechanisms of regulation of Foxp3 expression. Blood (2009) 2.27

CCL2 blockade augments cancer immunotherapy. Cancer Res (2009) 1.48

Peripheral CD4 loss of regulatory T cells is associated with persistent viraemia in chronic HIV infection. Clin Exp Immunol (2007) 1.24

Ex vivo generation of human alloantigen-specific regulatory T cells from CD4(pos)CD25(high) T cells for immunotherapy. PLoS One (2008) 1.16

Dicer insufficiency and microRNA-155 overexpression in lupus regulatory T cells: an apparent paradox in the setting of an inflammatory milieu. J Immunol (2010) 1.13

CD27 expression discriminates between regulatory and non-regulatory cells after expansion of human peripheral blood CD4+ CD25+ cells. Immunology (2007) 1.13

Extracellular NAD+ shapes the Foxp3+ regulatory T cell compartment through the ART2-P2X7 pathway. J Exp Med (2010) 1.13

VISTA Regulates the Development of Protective Antitumor Immunity. Cancer Res (2014) 1.09

Translational mini-review series on Th17 cells: CD4 T helper cells: functional plasticity and differential sensitivity to regulatory T cell-mediated regulation. Clin Exp Immunol (2009) 1.04

The role of CD4 T cells in the pathogenesis of murine AIDS. J Virol (2006) 0.98

Anti-CD4-mediated selection of Treg in vitro - in vitro suppression does not predict in vivo capacity to prevent graft rejection. Eur J Immunol (2008) 0.95

Signal peptide cleavage is essential for surface expression of a regulatory T cell surface protein, leucine rich repeat containing 32 (LRRC32). BMC Biochem (2011) 0.95

The B10 Idd9.3 locus mediates accumulation of functionally superior CD137(+) regulatory T cells in the nonobese diabetic type 1 diabetes model. J Immunol (2012) 0.92

Requirements for prolongation of allograft survival with regulatory T cell infusion in lymphosufficient hosts. J Surg Res (2011) 0.91

Therapy for pneumonitis and sialadenitis by accumulation of CCR2-expressing CD4+CD25+ regulatory T cells in MRL/lpr mice. Arthritis Res Ther (2007) 0.90

Therapeutic benefit of pentostatin in severe IL-10-/- colitis. Inflamm Bowel Dis (2008) 0.88

CD4+ primary T cells expressing HCV-core protein upregulate Foxp3 and IL-10, suppressing CD4 and CD8 T cells. PLoS One (2014) 0.87

Suppression of myasthenogenic responses of a T cell line by a dual altered peptide ligand by induction of CD4+CD25+ regulatory cells. Proc Natl Acad Sci U S A (2005) 0.87

MicroRNA regulation of T-lymphocyte immunity: modulation of molecular networks responsible for T-cell activation, differentiation, and development. Crit Rev Immunol (2013) 0.87

Regulatory cells and transplantation tolerance. Cold Spring Harb Perspect Med (2013) 0.86

Impact of dietary gluten on regulatory T cells and Th17 cells in BALB/c mice. PLoS One (2012) 0.85

Brown Recluse spider bite mediated hemolysis: clinical features, a possible role for complement inhibitor therapy, and reduced RBC surface glycophorin A as a potential biomarker of venom exposure. PLoS One (2013) 0.84

Regulatory T Cells Control Immune Responses through Their Non-Redundant Tissue Specific Features. Front Immunol (2013) 0.84

Intestinal microbiota sustains inflammation and autoimmunity induced by hypomorphic RAG defects. J Exp Med (2016) 0.84

Natural and expanded CD4(+)CD25(+) regulatory T cells in bone marrow transplantation. Biol Blood Marrow Transplant (2011) 0.82

Molecular epigenetics, chromatin, and NeuroAIDS/HIV: immunopathological implications. Bioinformation (2008) 0.81

Effects of oral commensal and pathogenic bacteria on human dendritic cells. Oral Microbiol Immunol (2009) 0.80

IL-33 Receptor-Expressing Regulatory T Cells Are Highly Activated, Th2 Biased and Suppress CD4 T Cell Proliferation through IL-10 and TGFβ Release. PLoS One (2016) 0.79

Higher frequency of regulatory T cells in granulocyte colony-stimulating factor (G-CSF)-primed bone marrow grafts compared with G-CSF-primed peripheral blood grafts. J Transl Med (2015) 0.78

Increased T regulatory cells lead to development of Th2 immune response in male SJL mice. Autoimmunity (2010) 0.77

MALT1 is an intrinsic regulator of regulatory T cells. Cell Death Differ (2015) 0.77

Freeze and Thaw of CD4+CD25+Foxp3+ Regulatory T Cells Results in Loss of CD62L Expression and a Reduced Capacity to Protect against Graft-versus-Host Disease. PLoS One (2015) 0.76

Utilization of leukapheresis and CD4 positive selection in Treg isolation and the ex-vivo expansion for a clinical application in transplantation and autoimmune disorders. Oncotarget (2016) 0.75

Induced Regulatory T Cells Superimpose Their Suppressive Capacity with Effector T Cells in Lymph Nodes via Antigen-Specific S1p1-Dependent Egress Blockage. Front Immunol (2017) 0.75

Manipulating IL-2 availability amid presentation of donor MHC antigens suppresses murine alloimmune responses by inducing regulatory T cells. PLoS One (2010) 0.75

Medicinal herbs Fructus corni and Semen cuscutae suppress allograft rejection via distinct immune mechanisms. Oncotarget (2016) 0.75

Induction of a Regulatory Phenotype in CD3+ CD4+ HLA-DR+ T Cells after Allogeneic Mixed Lymphocyte Culture; Indications of Both Contact-Dependent and -Independent Activation. Int J Mol Sci (2017) 0.75

Chinese medicine Ginseng and Astragalus granules ameliorate autoimmune diabetes by upregulating both CD4+FoxP3+ and CD8+CD122+PD1+ regulatory T cells. Oncotarget (2017) 0.75

Articles by these authors

Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus. Nature (2005) 8.55

Single-molecule analysis of dynein processivity and stepping behavior. Cell (2006) 5.63

Genes required for mitotic spindle assembly in Drosophila S2 cells. Science (2007) 5.58

Alloantigen-presenting plasmacytoid dendritic cells mediate tolerance to vascularized grafts. Nat Immunol (2006) 5.00

Augmin: a protein complex required for centrosome-independent microtubule generation within the spindle. J Cell Biol (2008) 4.10

Rat Genome Database (RGD): mapping disease onto the genome. Nucleic Acids Res (2002) 4.04

Type VI secretion is a major virulence determinant in Burkholderia mallei. Mol Microbiol (2007) 3.90

Detection of hepatocellular carcinoma at advanced stages among patients in the HALT-C trial: where did surveillance fail? Am J Gastroenterol (2013) 3.41

Regulatory T cells sequentially migrate from inflamed tissues to draining lymph nodes to suppress the alloimmune response. Immunity (2009) 3.32

Intrahepatic cholangiocarcinoma: rising frequency, improved survival, and determinants of outcome after resection. Ann Surg (2008) 3.16

TGF-beta induces Foxp3 + T-regulatory cells from CD4 + CD25 - precursors. Am J Transplant (2004) 3.15

Topological structure analysis of the protein-protein interaction network in budding yeast. Nucleic Acids Res (2003) 2.90

Epigenetic regulation of Foxp3 expression in regulatory T cells by DNA methylation. J Immunol (2009) 2.87

Allergen-induced asthmatic responses modified by a GATA3-specific DNAzyme. N Engl J Med (2015) 2.44

Circulating histones are mediators of trauma-associated lung injury. Am J Respir Crit Care Med (2012) 2.42

mdmx is a negative regulator of p53 activity in vivo. Cancer Res (2002) 2.40

Epigenetic mechanisms of regulation of Foxp3 expression. Blood (2009) 2.27

Presence of IL-5 protein and IgE antibodies to staphylococcal enterotoxins in nasal polyps is associated with comorbid asthma. J Allergy Clin Immunol (2010) 2.19

Massive ex vivo expansion of human natural regulatory T cells (T(regs)) with minimal loss of in vivo functional activity. Sci Transl Med (2011) 2.14

The sphingosine 1-phosphate receptor 1 causes tissue retention by inhibiting the entry of peripheral tissue T lymphocytes into afferent lymphatics. Nat Immunol (2007) 2.13

Sub-telomere directed gene expression during initiation of invasive aspergillosis. PLoS Pathog (2008) 2.09

C3PO, an endoribonuclease that promotes RNAi by facilitating RISC activation. Science (2009) 2.04

Increased tricuspid regurgitant jet velocity by Doppler echocardiography in adult survivors of childhood cancer: a report from the St Jude Lifetime Cohort Study. J Clin Oncol (2013) 2.03

c-Maf regulates IL-10 expression during Th17 polarization. J Immunol (2009) 1.99

Analysis of inflammatory cytokines in the tears of dry eye patients. Cornea (2009) 1.96

Donor Toll-like receptor 4 contributes to ischemia and reperfusion injury following human kidney transplantation. Proc Natl Acad Sci U S A (2009) 1.95

CCR7 signalling as an essential regulator of CNS infiltration in T-cell leukaemia. Nature (2009) 1.94

Craniofacial fibrous dysplasia associated with McCune-Albright syndrome. J Oral Maxillofac Surg (2009) 1.93

Pathogenesis of chronic rhinosinusitis: inflammation. J Allergy Clin Immunol (2011) 1.86

Hypoxia and hepatocellular carcinoma: The therapeutic target for hepatocellular carcinoma. J Gastroenterol Hepatol (2007) 1.83

Ureteral stents are associated with reduced risk of ureteral complications after kidney transplantation: a large single center experience. Transplantation (2012) 1.79

The bulge area is the origin of nestin-expressing pluripotent stem cells of the hair follicle. J Cell Biochem (2011) 1.74

A natural allele of Nxf1 suppresses retrovirus insertional mutations. Nat Genet (2003) 1.67

Transplant glomerulopathy may occur in the absence of donor-specific antibody and C4d staining. Clin J Am Soc Nephrol (2007) 1.64

Lymph node occupancy is required for the peripheral development of alloantigen-specific Foxp3+ regulatory T cells. J Immunol (2005) 1.64

A mouse model for Glut-1 haploinsufficiency. Hum Mol Genet (2006) 1.63

Role of staphylococcal superantigens in upper airway disease. Curr Opin Allergy Clin Immunol (2008) 1.59

Genome-wide association analyses in Han Chinese identify two new susceptibility loci for amyotrophic lateral sclerosis. Nat Genet (2013) 1.57

Monocytic suppressive cells mediate cardiovascular transplantation tolerance in mice. J Clin Invest (2010) 1.55

Pleiotrophin: a cytokine with diverse functions and a novel signaling pathway. Arch Biochem Biophys (2002) 1.52

Diphenhydramine as an adjunct to sedation for colonoscopy: a double-blind randomized, placebo-controlled study. Gastrointest Endosc (2006) 1.50

Long-term persistence of hepatitis B surface antigen and antibody induced by DNA-mediated immunization results in liver and kidney lesions in mice. Eur J Immunol (2006) 1.50

Sirolimus is associated with reduced islet engraftment and impaired beta-cell function. Diabetes (2006) 1.49

Failure rates in the hepatocellular carcinoma surveillance process. Cancer Prev Res (Phila) (2012) 1.49

Requirements for T lymphocyte migration in explanted lymph nodes. J Immunol (2007) 1.48

Determination of Cd, Co, Ni and Pb in biological samples by microcolumn packed with black stone (Pierre noire) online coupled with ICP-OES. J Hazard Mater (2008) 1.46

Cerebrospinal fluid apolipoprotein E concentration decreases after seizure. Seizure (2010) 1.45

Suppressor of cytokine signaling 1 inhibits IL-10-mediated immune responses. J Immunol (2003) 1.45

Smooth muscle cell-specific runx2 deficiency inhibits vascular calcification. Circ Res (2012) 1.45

Depression increases the risk of hypertension incidence: a meta-analysis of prospective cohort studies. J Hypertens (2012) 1.43

IL-6 plays a unique role in initiating c-Maf expression during early stage of CD4 T cell activation. J Immunol (2005) 1.42

Transcriptional profiling identifies a role for BrlA in the response to nitrogen depletion and for StuA in the regulation of secondary metabolite clusters in Aspergillus fumigatus. Eukaryot Cell (2008) 1.41

Clinical features and microsurgical treatment of pediatric patients with cerebral cavernous malformation. J Clin Neurosci (2011) 1.39

Antigen-specific immune responses to influenza vaccine in utero. J Clin Invest (2007) 1.36

Runx2-upregulated receptor activator of nuclear factor κB ligand in calcifying smooth muscle cells promotes migration and osteoclastic differentiation of macrophages. Arterioscler Thromb Vasc Biol (2011) 1.34

Genetic and neutralization sensitivity of diverse HIV-1 env clones from chronically infected patients in China. J Biol Chem (2011) 1.33

The Aspergillus fumigatus StuA protein governs the up-regulation of a discrete transcriptional program during the acquisition of developmental competence. Mol Biol Cell (2005) 1.31

Extended outbreak of cryptosporidiosis in a pediatric hospital, China. Emerg Infect Dis (2012) 1.30

Identification of a distant T-bet enhancer responsive to IL-12/Stat4 and IFNgamma/Stat1 signals. Blood (2007) 1.29

Specific IgE against Staphylococcus aureus enterotoxins: an independent risk factor for asthma. J Allergy Clin Immunol (2012) 1.28

Allogeneic mesenchymal stem cell treatment alleviates experimental and clinical Sjögren syndrome. Blood (2012) 1.27

Defective TiO2 with oxygen vacancies: synthesis, properties and photocatalytic applications. Nanoscale (2013) 1.25

Regulatory T cell infiltration predicts outcome following resection of colorectal cancer liver metastases. Ann Surg Oncol (2012) 1.24

Committing embryonic stem cells to early endocrine pancreas in vitro. Stem Cells (2004) 1.23

Screening adult survivors of childhood cancer for cardiomyopathy: comparison of echocardiography and cardiac magnetic resonance imaging. J Clin Oncol (2012) 1.23

Evaluation of biomarkers of inflammation in response to benzalkonium chloride on corneal and conjunctival epithelial cells. J Ocul Pharmacol Ther (2009) 1.22

Integrative genomics: in silico coupling of rat physiology and complex traits with mouse and human data. Genome Res (2004) 1.21

High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence. Genome Res (2004) 1.21

Super-stretchable, transparent carbon nanotube-based capacitive strain sensors for human motion detection. Sci Rep (2013) 1.19

De novo assembly of Euphorbia fischeriana root transcriptome identifies prostratin pathway related genes. BMC Genomics (2011) 1.18

An improved magnetic localization and orientation algorithm for wireless capsule endoscope. Conf Proc IEEE Eng Med Biol Soc (2008) 1.18

FTY720 stimulates multidrug transporter- and cysteinyl leukotriene-dependent T cell chemotaxis to lymph nodes. J Clin Invest (2003) 1.18

Evaluation of memory impairment in aging adult survivors of childhood acute lymphoblastic leukemia treated with cranial radiotherapy. J Natl Cancer Inst (2013) 1.17

Definition of regulatory network elements for T cell development by perturbation analysis with PU.1 and GATA-3. Dev Biol (2002) 1.17