Published in J Gen Virol on January 01, 2004
A mouse-adapted enterovirus 71 strain causes neurological disease in mice after oral infection. J Virol (2004) 2.10
The 3C protein of enterovirus 71 inhibits retinoid acid-inducible gene I-mediated interferon regulatory factor 3 activation and type I interferon responses. J Virol (2010) 1.66
Cleavage of the adaptor protein TRIF by enterovirus 71 3C inhibits antiviral responses mediated by Toll-like receptor 3. J Virol (2011) 1.61
Cooperative effect of the attenuation determinants derived from poliovirus sabin 1 strain is essential for attenuation of enterovirus 71 in the NOD/SCID mouse infection model. J Virol (2007) 1.54
A non-mouse-adapted enterovirus 71 (EV71) strain exhibits neurotropism, causing neurological manifestations in a novel mouse model of EV71 infection. J Virol (2011) 1.44
Sustained high levels of interleukin-6 contribute to the pathogenesis of enterovirus 71 in a neonate mouse model. J Virol (2011) 1.22
The cross-reactivity of the enterovirus 71 to human brain tissue and identification of the cross-reactivity related fragments. Virol J (2010) 1.12
Human SCARB2 transgenic mice as an infectious animal model for enterovirus 71. PLoS One (2013) 1.10
Atypical hand-foot-mouth disease in children: a hospital-based prospective cohort study. Virol J (2013) 1.02
Producing infectious enterovirus type 71 in a rapid strategy. Virol J (2010) 1.00
Transgenic mouse model for the study of enterovirus 71 neuropathogenesis. Proc Natl Acad Sci U S A (2013) 0.99
Attenuation of human enterovirus 71 high-replication-fidelity variants in AG129 mice. J Virol (2014) 0.93
Strategies to develop antivirals against enterovirus 71. Virol J (2013) 0.92
Human enterovirus 71 subgenotype B3 lacks coxsackievirus A16-like neurovirulence in mice infection. Virol J (2005) 0.92
Enterovirus 71-induced neurological disorders in young gerbils, Meriones unguiculatus: development and application of a neurological disease model. PLoS One (2012) 0.91
Sumoylation-promoted enterovirus 71 3C degradation correlates with a reduction in viral replication and cell apoptosis. J Biol Chem (2011) 0.88
Adaptation of enterovirus 71 to adult interferon deficient mice. PLoS One (2013) 0.88
Efficacy of a Trivalent Hand, Foot, and Mouth Disease Vaccine against Enterovirus 71 and Coxsackieviruses A16 and A6 in Mice. Viruses (2015) 0.85
Scavenger receptor b2 as a receptor for hand, foot, and mouth disease and severe neurological diseases. Front Microbiol (2012) 0.85
Enterovirus 71-induced autophagy increases viral replication and pathogenesis in a suckling mouse model. J Biomed Sci (2014) 0.83
Protective efficacy of VP1-specific neutralizing antibody associated with a reduction of viral load and pro-inflammatory cytokines in human SCARB2-transgenic mice. PLoS One (2013) 0.83
Animal models of enterovirus 71 infection: applications and limitations. J Biomed Sci (2014) 0.82
Immunodeficient mouse models with different disease profiles by in vivo infection with the same clinical isolate of enterovirus 71. J Virol (2014) 0.81
Necrotizing myositis causes restrictive hypoventilation in a mouse model for human enterovirus 71 infection. Virol J (2013) 0.80
Neuropathogenicity of Two Saffold Virus Type 3 Isolates in Mouse Models. PLoS One (2016) 0.80
Heat shock protein 90: role in enterovirus 71 entry and assembly and potential target for therapy. PLoS One (2013) 0.78
A Consistent Orally-Infected Hamster Model for Enterovirus A71 Encephalomyelitis Demonstrates Squamous Lesions in the Paws, Skin and Oral Cavity Reminiscent of Hand-Foot-and-Mouth Disease. PLoS One (2016) 0.78
Enterovirus 71 virion-associated galectin-1 facilitates viral replication and stability. PLoS One (2015) 0.78
Phenotypic and genotypic characteristics of novel mouse cell line (NIH/3T3)-adapted human enterovirus 71 strains (EV71:TLLm and EV71:TLLmv). PLoS One (2014) 0.78
Enterovirus 71 infection and neurological complications. Korean J Pediatr (2016) 0.78
Susceptibilities of enterovirus D68, enterovirus 71, and rhinovirus 87 strains to various antiviral compounds. Antiviral Res (2016) 0.77
An enterovirus 71 strain causes skeletal muscle damage in infected mice. Int J Clin Exp Pathol (2015) 0.77
Characterisation of enterovirus 71 replication kinetics in human colorectal cell line, HT29. Springerplus (2013) 0.77
Elucidating the host-pathogen interaction between human colorectal cells and invading Enterovirus 71 using transcriptomics profiling. FEBS Open Bio (2014) 0.76
Proteomic analysis of human brain microvascular endothelial cells reveals differential protein expression in response to enterovirus 71 infection. Biomed Res Int (2015) 0.75
A clinically authentic mouse model of enterovirus 71 (EV-A71)-induced neurogenic pulmonary oedema. Sci Rep (2016) 0.75
Enterovirus 71 infection of motor neuron-like NSC-34 cells undergoes a non-lytic exit pathway. Sci Rep (2016) 0.75
Delivery of human EV71 receptors by adeno-associated virus increases EV71 infection-induced local inflammation in adult mice. Biomed Res Int (2014) 0.75
The Preferential Infection of Astrocytes by Enterovirus 71 Plays a Key Role in the Viral Neurogenic Pathogenesis. Front Cell Infect Microbiol (2016) 0.75
Machine Learning Algorithms for Risk Prediction of Severe Hand-Foot-Mouth Disease in Children. Sci Rep (2017) 0.75
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy (2007) 20.92
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Milrinone therapy for enterovirus 71-induced pulmonary edema and/or neurogenic shock in children: a randomized controlled trial. Crit Care Med (2013) 2.88
CLEC5A is critical for dengue-virus-induced lethal disease. Nature (2008) 2.79
Waning immunity to plasma-derived hepatitis B vaccine and the need for boosters 15 years after neonatal vaccination. Hepatology (2004) 2.74
Change of major genotype of enterovirus 71 in outbreaks of hand-foot-and-mouth disease in Taiwan between 1998 and 2000. J Clin Microbiol (2002) 2.64
Genome sequencing and comparative analysis of Klebsiella pneumoniae NTUH-K2044, a strain causing liver abscess and meningitis. J Bacteriol (2009) 2.64
A revisit of prophylactic lamivudine for chemotherapy-associated hepatitis B reactivation in non-Hodgkin's lymphoma: a randomized trial. Hepatology (2008) 2.55
Dengue hemorrhagic fever in infants: a study of clinical and cytokine profiles. J Infect Dis (2004) 2.43
Reemergence of enterovirus 71 in 2008 in taiwan: dynamics of genetic and antigenic evolution from 1998 to 2008. J Clin Microbiol (2009) 2.40
Pathogenesis of enterovirus 71 brainstem encephalitis in pediatric patients: roles of cytokines and cellular immune activation in patients with pulmonary edema. J Infect Dis (2003) 2.36
Autophagic machinery activated by dengue virus enhances virus replication. Virology (2008) 2.23
Concanavalin A induces autophagy in hepatoma cells and has a therapeutic effect in a murine in situ hepatoma model. Hepatology (2007) 2.16
Steroid-free chemotherapy decreases risk of hepatitis B virus (HBV) reactivation in HBV-carriers with lymphoma. Hepatology (2003) 2.15
A mouse-adapted enterovirus 71 strain causes neurological disease in mice after oral infection. J Virol (2004) 2.10
A new urinary antigen test score correlates with severity of pneumococcal pneumonia in children. J Formos Med Assoc (2011) 2.05
Immature dengue virus: a veiled pathogen? PLoS Pathog (2010) 2.04
Childhood invasive pneumococcal disease caused by non-7-valent pneumococcal vaccine (PCV7) serotypes under partial immunization in Taiwan. J Formos Med Assoc (2013) 2.02
SARS in healthcare facilities, Toronto and Taiwan. Emerg Infect Dis (2004) 1.95
The dual-specific binding of dengue virus and target cells for the antibody-dependent enhancement of dengue virus infection. J Immunol (2006) 1.93
The 1998 enterovirus 71 outbreak in Taiwan: pathogenesis and management. Clin Infect Dis (2002) 1.90
Endoplasmic reticulum stress stimulates the expression of cyclooxygenase-2 through activation of NF-kappaB and pp38 mitogen-activated protein kinase. J Biol Chem (2004) 1.86
The autophagic induction in Helicobacter pylori-infected macrophage. Exp Biol Med (Maywood) (2008) 1.83
An interferon-gamma-related cytokine storm in SARS patients. J Med Virol (2005) 1.83
Establishing a nationwide emergency department-based syndromic surveillance system for better public health responses in Taiwan. BMC Public Health (2008) 1.81
Complete nucleotide sequence of pK245, a 98-kilobase plasmid conferring quinolone resistance and extended-spectrum-beta-lactamase activity in a clinical Klebsiella pneumoniae isolate. Antimicrob Agents Chemother (2006) 1.76
Antibodies from dengue patient sera cross-react with endothelial cells and induce damage. J Med Virol (2003) 1.72
Epidemiological survey of enterovirus infections occurring in Taiwan between 2000 and 2005: analysis of sentinel physician surveillance data. J Med Virol (2007) 1.69
Sensitive and quantitative detection of severe acute respiratory syndrome coronavirus infection by real-time nested polymerase chain reaction. Clin Infect Dis (2003) 1.68
Pre-S mutant surface antigens in chronic hepatitis B virus infection induce oxidative stress and DNA damage. Carcinogenesis (2004) 1.67
Characterization of severe acute respiratory syndrome coronavirus genomes in Taiwan: molecular epidemiology and genome evolution. Proc Natl Acad Sci U S A (2004) 1.66
Hepatitis B virus pre-S mutants, endoplasmic reticulum stress and hepatocarcinogenesis. Cancer Sci (2006) 1.64
MCP-1, a highly expressed chemokine in dengue haemorrhagic fever/dengue shock syndrome patients, may cause permeability change, possibly through reduced tight junctions of vascular endothelium cells. J Gen Virol (2006) 1.63
Pre-S2 deletion mutants of hepatitis B virus could have an important role in hepatocarcinogenesis in Asian children. Cancer Sci (2009) 1.61
Retrograde axonal transport: a major transmission route of enterovirus 71 in mice. J Virol (2007) 1.61
Correlation of serum levels of macrophage migration inhibitory factor with disease severity and clinical outcome in dengue patients. Am J Trop Med Hyg (2006) 1.61
Molecular epidemiology and evolutionary genetics of Mycobacterium tuberculosis in Taipei. BMC Infect Dis (2008) 1.59
All chronic rejection failures of kidney transplants were preceded by the development of HLA antibodies. Transplantation (2002) 1.58
Type I interferons protect mice against enterovirus 71 infection. J Gen Virol (2005) 1.57
Mitochondrial fission contributes to mitochondrial dysfunction and insulin resistance in skeletal muscle. Mol Cell Biol (2011) 1.55
Effect of type 2 diabetes mellitus on the clinical severity and treatment outcome in patients with pulmonary tuberculosis: a potential role in the emergence of multidrug-resistance. J Formos Med Assoc (2011) 1.53
Humoral and cellular immune responses to a hepatitis B vaccine booster 15-18 years after neonatal immunization. J Infect Dis (2008) 1.43
Endothelial cell apoptosis induced by antibodies against dengue virus nonstructural protein 1 via production of nitric oxide. J Immunol (2002) 1.40
IL-19 induced Th2 cytokines and was up-regulated in asthma patients. J Immunol (2004) 1.39
Different types of ground glass hepatocytes in chronic hepatitis B virus infection contain specific pre-S mutants that may induce endoplasmic reticulum stress. Am J Pathol (2003) 1.39
Modulation of cytokine production by intravenous immunoglobulin in patients with enterovirus 71-associated brainstem encephalitis. J Clin Virol (2006) 1.39
Enterovirus 71: epidemiology, pathogenesis and management. Expert Rev Anti Infect Ther (2009) 1.36
Long-term results of anti-Helicobacter pylori therapy in early-stage gastric high-grade transformed MALT lymphoma. J Natl Cancer Inst (2005) 1.35
Hepatitis B virus pre-S2 mutant upregulates cyclin A expression and induces nodular proliferation of hepatocytes. Hepatology (2005) 1.35
Interleukin-17-producing cell infiltration in the breast cancer tumour microenvironment is a poor prognostic factor. Histopathology (2013) 1.35
Association between sex, nutritional status, severity of dengue hemorrhagic fever, and immune status in infants with dengue hemorrhagic fever. Am J Trop Med Hyg (2005) 1.34
1998 dengue hemorrhagic fever epidemic in Taiwan. Emerg Infect Dis (2004) 1.33
Autoimmune pathogenesis in dengue virus infection. Viral Immunol (2006) 1.32
Intracellular localization and determination of a nuclear localization signal of the core protein of dengue virus. J Gen Virol (2002) 1.32
Challenges to licensure of enterovirus 71 vaccines. PLoS Negl Trop Dis (2012) 1.31
Sequencing and comparative genomic analysis of pK29, a 269-kilobase conjugative plasmid encoding CMY-8 and CTX-M-3 beta-lactamases in Klebsiella pneumoniae. Antimicrob Agents Chemother (2007) 1.28
Acute chemokine response in the blood and cerebrospinal fluid of children with enterovirus 71-associated brainstem encephalitis. J Infect Dis (2008) 1.28
Laboratory-based surveillance and molecular epidemiology of influenza virus in Taiwan. J Clin Microbiol (2005) 1.26
Expression of cytokine, chemokine, and adhesion molecules during endothelial cell activation induced by antibodies against dengue virus nonstructural protein 1. J Immunol (2005) 1.26
Virus replication and cytokine production in dengue virus-infected human B lymphocytes. J Virol (2002) 1.25
Enterovirus 71, one virus and many stories. Pediatr Neonatol (2008) 1.22
Heparin inhibits dengue-2 virus infection of five human liver cell lines. Antiviral Res (2002) 1.21
Immunohistochemical, in situ hybridization, and ultrastructural localization of SARS-associated coronavirus in lung of a fatal case of severe acute respiratory syndrome in Taiwan. Hum Pathol (2005) 1.21