Published in J Infect Dis on December 30, 2003
A pneumococcal pilus influences virulence and host inflammatory responses. Proc Natl Acad Sci U S A (2006) 4.40
SpxB is a suicide gene of Streptococcus pneumoniae and confers a selective advantage in an in vivo competitive colonization model. J Bacteriol (2007) 1.48
Influences of capsule on cell shape and chain formation of wild-type and pcsB mutants of serotype 2 Streptococcus pneumoniae. J Bacteriol (2009) 1.33
Modifications to the peptidoglycan backbone help bacteria to establish infection. Infect Immun (2010) 1.22
Sortase-mediated assembly and surface topology of adhesive pneumococcal pili. Mol Microbiol (2008) 1.22
Streptococcus pneumoniae evades human dendritic cell surveillance by pneumolysin expression. EMBO Mol Med (2009) 1.19
Revising the role of the pneumococcal vex-vncRS locus in vancomycin tolerance. J Bacteriol (2004) 0.99
A point mutation in cpsE renders Streptococcus pneumoniae nonencapsulated and enhances its growth, adherence and competence. BMC Microbiol (2014) 0.97
Human monocytes promote Th1 and Th17 responses to Streptococcus pneumoniae. Infect Immun (2011) 0.96
Decrease in penicillin susceptibility due to heat shock protein ClpL in Streptococcus pneumoniae. Antimicrob Agents Chemother (2011) 0.95
Intravitreal daptomycin: a safety and efficacy study. Retina (2011) 0.94
The capsule sensitizes Streptococcus pneumoniae to alpha-defensins human neutrophil proteins 1 to 3. Infect Immun (2008) 0.85
Influenza A virus-mediated priming enhances cytokine secretion by human dendritic cells infected with Streptococcus pneumoniae. Cell Microbiol (2013) 0.81
Microscale insights into pneumococcal antibiotic mutant selection windows. Nat Commun (2015) 0.78
Antibiotic activity against naive and induced Streptococcus pneumoniae biofilms in an in vitro pharmacodynamic model. Antimicrob Agents Chemother (2013) 0.77
Increased Zinc Availability Enhances Initial Aggregation and Biofilm Formation of Streptococcus pneumoniae. Front Cell Infect Microbiol (2017) 0.75
Cinobufagin Modulates Human Innate Immune Responses and Triggers Antibacterial Activity. PLoS One (2016) 0.75
Pyruvate oxidase of Streptococcus pneumoniae contributes to pneumolysin release. BMC Microbiol (2016) 0.75
Transcriptional Repressor PtvR Regulates Phenotypic Tolerance to Vancomycin in Streptococcus pneumoniae. J Bacteriol (2017) 0.75
Abundance and co-occurrence of extracellular capsules increases environmental breadth: Implications for the emergence of pathogens. PLoS Pathog (2017) 0.75
Role of Escherichia coli curli operons in directing amyloid fiber formation. Science (2002) 5.58
An endonuclease allows Streptococcus pneumoniae to escape from neutrophil extracellular traps. Curr Biol (2006) 3.69
Functional adaptation of BabA, the H. pylori ABO blood group antigen binding adhesin. Science (2004) 3.06
Toll-like receptor 4 resides in the Golgi apparatus and colocalizes with internalized lipopolysaccharide in intestinal epithelial cells. J Exp Med (2002) 2.53
Bacterial adhesins in host-microbe interactions. Cell Host Microbe (2009) 2.43
Identification of a Candidate Streptococcus pneumoniae core genome and regions of diversity correlated with invasive pneumococcal disease. Infect Immun (2006) 2.33
Bacterial strategies for overcoming host innate and adaptive immune responses. Nat Immunol (2002) 2.33
The Salmonella enterica subspecies I specific centisome 7 genomic island encodes novel protein families present in bacteria living in close contact with eukaryotic cells. Res Microbiol (2002) 2.18
Intracellular recognition of lipopolysaccharide by toll-like receptor 4 in intestinal epithelial cells. J Exp Med (2003) 2.05
A small-molecule inhibitor of type III secretion inhibits different stages of the infectious cycle of Chlamydia trachomatis. Proc Natl Acad Sci U S A (2006) 2.01
Capsule and D-alanylated lipoteichoic acids protect Streptococcus pneumoniae against neutrophil extracellular traps. Cell Microbiol (2007) 1.99
Synthesis of group A streptococcal virulence factors is controlled by a regulatory RNA molecule. Mol Microbiol (2004) 1.92
Intraclonal variations among Streptococcus pneumoniae isolates influence the likelihood of invasive disease in children. J Infect Dis (2013) 1.84
Polynucleotide phosphorylase is a global regulator of virulence and persistency in Salmonella enterica. Proc Natl Acad Sci U S A (2002) 1.83
Neutrophil extracellular traps: casting the NET over pathogenesis. Curr Opin Microbiol (2007) 1.80
Intravenous zanamivir for oseltamivir-resistant 2009 H1N1 influenza. N Engl J Med (2009) 1.79
Defective development and function of Bcl10-deficient follicular, marginal zone and B1 B cells. Nat Immunol (2003) 1.70
Molecular and clinical characteristics of invasive group A streptococcal infection in Sweden. Clin Infect Dis (2007) 1.66
Toll-like receptor 9 acts at an early stage in host defence against pneumococcal infection. Cell Microbiol (2006) 1.62
Emergence of hypervirulent mutants resistant to early clearance during systemic serotype 1 pneumococcal infection in mice and humans. J Infect Dis (2014) 1.62
Myeloid differentiation factor 88-dependent signalling controls bacterial growth during colonization and systemic pneumococcal disease in mice. Cell Microbiol (2005) 1.59
Toxin-gene profile heterogeneity among endemic invasive European group A streptococcal isolates. J Infect Dis (2003) 1.56
Virulence in mice of pneumococcal clonal types with known invasive disease potential in humans. J Infect Dis (2005) 1.51
Streptococcus pneumoniae contains 3 rlrA pilus variants that are clonally related. J Infect Dis (2008) 1.49
Solution structure of choline binding protein A, the major adhesin of Streptococcus pneumoniae. EMBO J (2004) 1.47
Organ-specific models of Streptococcus pneumoniae disease. Scand J Infect Dis (2003) 1.47
The Escherichia coli BarA-UvrY two-component system is needed for efficient switching between glycolytic and gluconeogenic carbon sources. J Bacteriol (2003) 1.44
Gastric mucosal recognition of Helicobacter pylori is independent of Toll-like receptor 4. J Infect Dis (2003) 1.39
Influence of neutropenia on the course of serotype 8 pneumococcal pneumonia in mice. Infect Immun (2007) 1.36
Roles of curli, cellulose and BapA in Salmonella biofilm morphology studied by atomic force microscopy. BMC Microbiol (2007) 1.33
Calcium efflux is essential for bacterial survival in the eukaryotic host. Mol Microbiol (2008) 1.33
The rise and fall of bacterial clones: Streptococcus pneumoniae. Nat Rev Microbiol (2008) 1.32
Correlation between cag pathogenicity island composition and Helicobacter pylori-associated gastroduodenal disease. Infect Immun (2003) 1.32
Structural requirements for TLR4-mediated LPS signalling: a biological role for LPS modifications. Microbes Infect (2003) 1.30
High abundance of virulence gene homologues in marine bacteria. Environ Microbiol (2009) 1.27
LytA, major autolysin of Streptococcus pneumoniae, requires access to nascent peptidoglycan. J Biol Chem (2012) 1.23
Site-specific manifestations of invasive group a streptococcal disease: type distribution and corresponding patterns of virulence determinants. J Clin Microbiol (2003) 1.23
The TLR2-MyD88-NOD2-RIPK2 signalling axis regulates a balanced pro-inflammatory and IL-10-mediated anti-inflammatory cytokine response to Gram-positive cell walls. Cell Microbiol (2008) 1.23
Sortase-mediated assembly and surface topology of adhesive pneumococcal pili. Mol Microbiol (2008) 1.22
Convergence of regulatory networks on the pilus locus of Streptococcus pneumoniae. Infect Immun (2008) 1.20
Determination of accessory gene patterns predicts the same relatedness among strains of Streptococcus pneumoniae as sequencing of housekeeping genes does and represents a novel approach in molecular epidemiology. J Clin Microbiol (2007) 1.20
Pax3-FKHR knock-in mice show developmental aberrations but do not develop tumors. Mol Cell Biol (2002) 1.20
Streptococcus pneumoniae evades human dendritic cell surveillance by pneumolysin expression. EMBO Mol Med (2009) 1.19
Differences in potency of intravenous polyspecific immunoglobulin G against streptococcal and staphylococcal superantigens: implications for therapy of toxic shock syndrome. Clin Infect Dis (2004) 1.18
Dominant role of nucleotide substitution in the diversification of serotype 3 pneumococci over decades and during a single infection. PLoS Genet (2013) 1.17
Molecular characterization of the acid-inducible asr gene of Escherichia coli and its role in acid stress response. J Bacteriol (2003) 1.16
Noninvasive monitoring of pneumococcal meningitis and evaluation of treatment efficacy in an experimental mouse model. Mol Imaging (2005) 1.13
Group A streptococcal infections in Sweden: a comparative study of invasive and noninvasive infections and analysis of dominant T28 emm28 isolates. Clin Infect Dis (2003) 1.13
Disulfide bond formation and cysteine exclusion in gram-positive bacteria. J Biol Chem (2009) 1.09
An enzymatic ruler modulates Lewis antigen glycosylation of Helicobacter pylori LPS during persistent infection. Proc Natl Acad Sci U S A (2006) 1.09
Two crystal structures of pneumococcal pilus sortase C provide novel insights into catalysis and substrate specificity. J Mol Biol (2009) 1.05
Vancomycin stress response in a sensitive and a tolerant strain of Streptococcus pneumoniae. J Bacteriol (2005) 1.04
Lipopolysaccharide diversity evolving in Helicobacter pylori communities through genetic modifications in fucosyltransferases. PLoS One (2008) 1.02
Contribution of host, bacterial factors and antibiotic treatment to mortality in adult patients with bacteraemic pneumococcal pneumonia. Thorax (2013) 1.02
Components of the peptidoglycan-recycling pathway modulate invasion and intracellular survival of Salmonella enterica serovar Typhimurium. Cell Microbiol (2005) 1.00
Studies on the antibacterial effects of statins--in vitro and in vivo. PLoS One (2011) 1.00
Inhibition of T cells provides protection against early invasive pneumococcal disease. Infect Immun (2010) 1.00
Mechanistic basis for the action of new cephalosporin antibiotics effective against methicillin- and vancomycin-resistant Staphylococcus aureus. J Biol Chem (2006) 1.00
Revising the role of the pneumococcal vex-vncRS locus in vancomycin tolerance. J Bacteriol (2004) 0.99
TLR4-dependent recognition of lipopolysaccharide by epithelial cells requires sCD14. Cell Microbiol (2002) 0.99
Fimbriae, pili, flagella and bacterial virulence. Contrib Microbiol (2005) 0.99
Hypersusceptibility to invasive pneumococcal infection in experimental sickle cell disease involves platelet-activating factor receptor. J Infect Dis (2007) 0.97
Small molecule inhibitors of the Yersinia type III secretion system impair the development of Chlamydia after entry into host cells. BMC Microbiol (2009) 0.94
Immunohistochemical stains for p63 and alpha-methylacyl-CoA racemase, versus a cocktail comprising both, in the diagnosis of prostatic carcinoma: a comparison of the immunohistochemical staining of 430 foci in radical prostatectomy and needle biopsy tissues. Am J Surg Pathol (2005) 0.94
Genetic and functional characterization of the Escherichia coli BarA-UvrY two-component system: point mutations in the HAMP linker of the BarA sensor give a dominant-negative phenotype. J Bacteriol (2005) 0.94
Cytokine secretion requires phosphatidylcholine synthesis. J Cell Biol (2008) 0.94
Identification of a family of effectors secreted by the type III secretion system that are conserved in pathogenic Chlamydiae. Infect Immun (2010) 0.93
The Escherichia coli BarA-UvrY two-component system is a virulence determinant in the urinary tract. BMC Microbiol (2006) 0.93
Focal targeting by human β-defensin 2 disrupts localized virulence factor assembly sites in Enterococcus faecalis. Proc Natl Acad Sci U S A (2013) 0.93
A changing gastric environment leads to adaptation of lipopolysaccharide variants in Helicobacter pylori populations during colonization. PLoS One (2009) 0.91
Tolerance to vancomycin in pneumococci: detection with a molecular marker and assessment of clinical impact. J Infect Dis (2004) 0.91
Structural and functional insights into peptidoglycan access for the lytic amidase LytA of Streptococcus pneumoniae. MBio (2014) 0.90
Pilin and sortase residues critical for endocarditis- and biofilm-associated pilus biogenesis in Enterococcus faecalis. J Bacteriol (2013) 0.90
Commensal pathogens, with a focus on Streptococcus pneumoniae, and interactions with the human host. Exp Cell Res (2010) 0.89
Transcriptional analysis of the acid-inducible asr gene in enterobacteria. Res Microbiol (2004) 0.89
Type I interferon protects against pneumococcal invasive disease by inhibiting bacterial transmigration across the lung. PLoS Pathog (2013) 0.88
Pilus adhesin RrgA interacts with complement receptor 3, thereby affecting macrophage function and systemic pneumococcal disease. MBio (2012) 0.88
Persistent infection with Helicobacter pylori and the development of gastric cancer. Adv Cancer Res (2003) 0.87
Penicillin-resistant pneumococci in Sweden 1997-2003: increased multiresistance despite stable prevalence and decreased antibiotic use. Microb Drug Resist (2006) 0.86
The influence of in vitro fitness defects on pneumococcal ability to colonize and to cause invasive disease. BMC Microbiol (2008) 0.86
The capsule sensitizes Streptococcus pneumoniae to alpha-defensins human neutrophil proteins 1 to 3. Infect Immun (2008) 0.85
A method for metagenomics of Helicobacter pylori from archived formalin-fixed gastric biopsies permitting longitudinal studies of carcinogenic risk. PLoS One (2011) 0.85
TLR4-dependent lipopolysaccharide signalling in epithelial cells is independent of extracellular protease activity. Cell Microbiol (2002) 0.85
The basic keratin 10-binding domain of the virulence-associated pneumococcal serine-rich protein PsrP adopts a novel MSCRAMM fold. Open Biol (2014) 0.85
Effects of a large-scale introduction of the pneumococcal polysaccharide vaccine among elderly persons in Stockholm, Sweden. Vaccine (2008) 0.84
Identification of heparin/heparan sulfate interacting protein as a major broad-spectrum antimicrobial protein in lung and small intestine. FASEB J (2008) 0.83
Comprehensive antigen screening identifies Moraxella catarrhalis proteins that induce protection in a mouse pulmonary clearance model. PLoS One (2013) 0.83
The function and biological role of toll-like receptors in infectious diseases: an update. Curr Opin Infect Dis (2008) 0.82
Bacterial evasion of innate defense at epithelial linings. Chem Immunol Allergy (2005) 0.81
Influenza A virus-mediated priming enhances cytokine secretion by human dendritic cells infected with Streptococcus pneumoniae. Cell Microbiol (2013) 0.81