Polysaccharide intercellular adhesin (PIA) protects Staphylococcus epidermidis against major components of the human innate immune system.

PubWeight™: 3.26‹?› | Rank: Top 1%

🔗 View Article (PMID 14764110)

Published in Cell Microbiol on March 01, 2004

Authors

Cuong Vuong1, Jovanka M Voyich, Elizabeth R Fischer, Kevin R Braughton, Adeline R Whitney, Frank R DeLeo, Michael Otto

Author Affiliations

1: Laboratories of Human Bacterial Pathogenesis, National Institute of Allergy and Infectious Diseases, National Institute of Health, Hamilton, MT 59840, USA.

Articles citing this

(truncated to the top 100)

Staphylococcus epidermidis--the 'accidental' pathogen. Nat Rev Microbiol (2009) 5.34

Staphylococcal biofilms. Curr Top Microbiol Immunol (2008) 4.26

The CNS role of Toll-like receptor 4 in innate neuroimmunity and painful neuropathy. Proc Natl Acad Sci U S A (2005) 3.59

Differential roles of poly-N-acetylglucosamine surface polysaccharide and extracellular DNA in Staphylococcus aureus and Staphylococcus epidermidis biofilms. Appl Environ Microbiol (2007) 2.90

Staphylococcus epidermidis Esp inhibits Staphylococcus aureus biofilm formation and nasal colonization. Nature (2010) 2.85

Genes involved in the synthesis and degradation of matrix polysaccharide in Actinobacillus actinomycetemcomitans and Actinobacillus pleuropneumoniae biofilms. J Bacteriol (2004) 2.46

Comparative opsonic and protective activities of Staphylococcus aureus conjugate vaccines containing native or deacetylated Staphylococcal Poly-N-acetyl-beta-(1-6)-glucosamine. Infect Immun (2005) 2.37

Neutrophils in innate host defense against Staphylococcus aureus infections. Semin Immunopathol (2011) 2.17

Polymicrobial interactions: impact on pathogenesis and human disease. Clin Microbiol Rev (2012) 2.14

Emergence of Pseudomonas aeruginosa strains producing high levels of persister cells in patients with cystic fibrosis. J Bacteriol (2010) 2.11

The pgaABCD locus of Acinetobacter baumannii encodes the production of poly-beta-1-6-N-acetylglucosamine, which is critical for biofilm formation. J Bacteriol (2009) 2.06

Roles of pgaABCD genes in synthesis, modification, and export of the Escherichia coli biofilm adhesin poly-beta-1,6-N-acetyl-D-glucosamine. J Bacteriol (2008) 2.02

Host defense and pathogenesis in Staphylococcus aureus infections. Infect Dis Clin North Am (2009) 2.01

Characterization of the ebp(fm) pilus-encoding operon of Enterococcus faecium and its role in biofilm formation and virulence in a murine model of urinary tract infection. Virulence (2011) 1.80

Poly-N-acetylglucosamine production in Staphylococcus aureus is essential for virulence in murine models of systemic infection. Infect Immun (2005) 1.80

A zinc-dependent adhesion module is responsible for intercellular adhesion in staphylococcal biofilms. Proc Natl Acad Sci U S A (2008) 1.70

Current concepts in biofilm formation of Staphylococcus epidermidis. Future Microbiol (2010) 1.67

Key role of poly-gamma-DL-glutamic acid in immune evasion and virulence of Staphylococcus epidermidis. J Clin Invest (2005) 1.64

Staphylococcus epidermidis strategies to avoid killing by human neutrophils. PLoS Pathog (2010) 1.60

Staphylococcal biofilm exopolysaccharide protects against Caenorhabditis elegans immune defenses. PLoS Pathog (2007) 1.58

Role of a putative polysaccharide locus in Bordetella biofilm development. J Bacteriol (2006) 1.50

Poly-N-acetylglucosamine mediates biofilm formation and antibiotic resistance in Actinobacillus pleuropneumoniae. Microb Pathog (2007) 1.49

Putative surface proteins encoded within a novel transferable locus confer a high-biofilm phenotype to Enterococcus faecalis. J Bacteriol (2006) 1.47

ATP-Dependent Persister Formation in Escherichia coli. MBio (2017) 1.46

Staphylococcus epidermidis polysaccharide intercellular adhesin production significantly increases during tricarboxylic acid cycle stress. J Bacteriol (2005) 1.44

Uropathogenic Escherichia coli modulates immune responses and its curli fimbriae interact with the antimicrobial peptide LL-37. PLoS Pathog (2010) 1.41

Role of surface protein SasG in biofilm formation by Staphylococcus aureus. J Bacteriol (2010) 1.40

Bacterial biofilms: development, dispersal, and therapeutic strategies in the dawn of the postantibiotic era. Cold Spring Harb Perspect Med (2013) 1.38

Quantitative analysis of adhesion and biofilm formation on hydrophilic and hydrophobic surfaces of clinical isolates of Staphylococcus epidermidis. Res Microbiol (2005) 1.38

Antimicrobial peptides. Pharmaceuticals (Basel) (2013) 1.37

Clonal analysis of Staphylococcus epidermidis isolates carrying or lacking biofilm-mediating genes by multilocus sequence typing. J Clin Microbiol (2005) 1.36

Transit through the flea vector induces a pretransmission innate immunity resistance phenotype in Yersinia pestis. PLoS Pathog (2010) 1.36

Protection against Escherichia coli infection by antibody to the Staphylococcus aureus poly-N-acetylglucosamine surface polysaccharide. Proc Natl Acad Sci U S A (2007) 1.34

Complex regulatory pathways coordinate cell-cycle progression and development in Caulobacter crescentus. Adv Microb Physiol (2009) 1.32

The use of superparamagnetic nanoparticles for prosthetic biofilm prevention. Int J Nanomedicine (2009) 1.25

The Bps polysaccharide of Bordetella pertussis promotes colonization and biofilm formation in the nose by functioning as an adhesin. Mol Microbiol (2010) 1.25

Yersinia pestis biofilm in the flea vector and its role in the transmission of plague. Curr Top Microbiol Immunol (2008) 1.25

Molecular basis of in vivo biofilm formation by bacterial pathogens. Chem Biol (2012) 1.23

Poly-N-acetylglucosamine mediates biofilm formation and detergent resistance in Aggregatibacter actinomycetemcomitans. Microb Pathog (2007) 1.22

Understanding the significance of Staphylococcus epidermidis bacteremia in babies and children. Curr Opin Infect Dis (2010) 1.20

Characterization of the Caulobacter crescentus holdfast polysaccharide biosynthesis pathway reveals significant redundancy in the initiating glycosyltransferase and polymerase steps. J Bacteriol (2008) 1.19

Naturally processed dermcidin-derived peptides do not permeabilize bacterial membranes and kill microorganisms irrespective of their charge. Antimicrob Agents Chemother (2006) 1.18

Tricarboxylic acid cycle-dependent regulation of Staphylococcus epidermidis polysaccharide intercellular adhesin synthesis. J Bacteriol (2008) 1.17

Neonatal sepsis due to coagulase-negative staphylococci. Clin Dev Immunol (2013) 1.16

Staphylococcus epidermidis uses distinct mechanisms of biofilm formation to interfere with phagocytosis and activation of mouse macrophage-like cells 774A.1. Infect Immun (2011) 1.16

Interaction of Candida albicans with adherent human peripheral blood mononuclear cells increases C. albicans biofilm formation and results in differential expression of pro- and anti-inflammatory cytokines. Infect Immun (2007) 1.16

A stochastic mechanism for biofilm formation by Mycoplasma pulmonis. J Bacteriol (2006) 1.15

Extracellular DNA is essential for maintaining Bordetella biofilm integrity on abiotic surfaces and in the upper respiratory tract of mice. PLoS One (2011) 1.12

Comparative antibody-mediated phagocytosis of Staphylococcus epidermidis cells grown in a biofilm or in the planktonic state. Infect Immun (2006) 1.10

Reversible daptomycin tolerance of adherent staphylococci in an implant infection model. Antimicrob Agents Chemother (2011) 1.10

Looking toward basic science for potential drug discovery targets against community-associated MRSA. Med Res Rev (2010) 1.08

Borrelia burgdorferi, the Causative Agent of Lyme Disease, Forms Drug-Tolerant Persister Cells. Antimicrob Agents Chemother (2015) 1.08

Novel targeted immunotherapy approaches for staphylococcal infection. Expert Opin Biol Ther (2010) 1.07

Extracellular DNA-dependent biofilm formation by Staphylococcus epidermidis RP62A in response to subminimal inhibitory concentrations of antibiotics. Res Microbiol (2011) 1.06

Modality of bacterial growth presents unique targets: how do we treat biofilm-mediated infections? Curr Opin Microbiol (2010) 1.06

Synergistic activity of dispersin B and cefamandole nafate in inhibition of staphylococcal biofilm growth on polyurethanes. Antimicrob Agents Chemother (2007) 1.04

Biofilms protect Mycoplasma pulmonis cells from lytic effects of complement and gramicidin. Infect Immun (2007) 1.04

Staphylococcus colonization of the skin and antimicrobial peptides. Expert Rev Dermatol (2010) 1.03

Loss of a biofilm-inhibiting glycosyl hydrolase during the emergence of Yersinia pestis. J Bacteriol (2008) 1.03

Bacterial sensing of antimicrobial peptides. Contrib Microbiol (2009) 1.03

Structural basis for Zn2+-dependent intercellular adhesion in staphylococcal biofilms. Proc Natl Acad Sci U S A (2012) 1.02

Genetic dissection of an exogenously induced biofilm in laboratory and clinical isolates of E. coli. PLoS Pathog (2009) 1.02

Transposon mutagenesis identifies uropathogenic Escherichia coli biofilm factors. J Bacteriol (2012) 1.02

Both leukotoxin and poly-N-acetylglucosamine surface polysaccharide protect Aggregatibacter actinomycetemcomitans cells from macrophage killing. Microb Pathog (2008) 1.01

Comparison of methods for the detection of biofilm production in coagulase-negative staphylococci. BMC Res Notes (2010) 1.01

Bap, a biofilm matrix protein of Staphylococcus aureus prevents cellular internalization through binding to GP96 host receptor. PLoS Pathog (2012) 1.00

Antibiofilm activity of an exopolysaccharide from marine bacterium Vibrio sp. QY101. PLoS One (2011) 0.99

Biofilms in periprosthetic orthopedic infections. Future Microbiol (2014) 0.99

Using NMR metabolomics to investigate tricarboxylic acid cycle-dependent signal transduction in Staphylococcus epidermidis. J Biol Chem (2010) 0.98

Subdomains N2N3 of fibronectin binding protein A mediate Staphylococcus aureus biofilm formation and adherence to fibrinogen using distinct mechanisms. J Bacteriol (2013) 0.97

Crystal structure of IcaR, a repressor of the TetR family implicated in biofilm formation in Staphylococcus epidermidis. Nucleic Acids Res (2008) 0.96

Polysaccharide intercellular adhesin in biofilm: structural and regulatory aspects. Front Cell Infect Microbiol (2015) 0.96

Structural study of TcaR and its complexes with multiple antibiotics from Staphylococcus epidermidis. Proc Natl Acad Sci U S A (2010) 0.96

Neonatal immune adaptation of the gut and its role during infections. Clin Dev Immunol (2013) 0.95

SarZ is a key regulator of biofilm formation and virulence in Staphylococcus epidermidis. J Infect Dis (2008) 0.95

Structure-activity analysis of the dermcidin-derived peptide DCD-1L, an anionic antimicrobial peptide present in human sweat. J Biol Chem (2012) 0.94

Insulin treatment modulates the host immune system to enhance Pseudomonas aeruginosa wound biofilms. Infect Immun (2013) 0.94

Strategies to potentiate antimicrobial photoinactivation by overcoming resistant phenotypes. Photochem Photobiol (2012) 0.94

Gene expression profile and pathogenicity of biofilm-forming Prevotella intermedia strain 17. BMC Microbiol (2009) 0.93

Dermcidin-derived peptides show a different mode of action than the cathelicidin LL-37 against Staphylococcus aureus. Antimicrob Agents Chemother (2009) 0.92

Dermal neutrophil, macrophage and dendritic cell responses to Yersinia pestis transmitted by fleas. PLoS Pathog (2015) 0.92

Inhibition of Staphylococcus epidermidis biofilm by trimethylsilane plasma coating. Antimicrob Agents Chemother (2012) 0.92

Characterization of the poly-β-1,6-N-acetylglucosamine polysaccharide component of Burkholderia biofilms. Appl Environ Microbiol (2011) 0.91

Enzymatic modifications of exopolysaccharides enhance bacterial persistence. Front Microbiol (2015) 0.91

An extracellular Staphylococcus epidermidis polysaccharide: relation to Polysaccharide Intercellular Adhesin and its implication in phagocytosis. BMC Microbiol (2012) 0.90

Poly-N-acetylglucosamine matrix polysaccharide impedes fluid convection and transport of the cationic surfactant cetylpyridinium chloride through bacterial biofilms. Appl Environ Microbiol (2008) 0.90

Structural basis of Staphylococcus epidermidis biofilm formation: mechanisms and molecular interactions. Front Cell Infect Microbiol (2015) 0.90

A non-coding RNA promotes bacterial persistence and decreases virulence by regulating a regulator in Staphylococcus aureus. PLoS Pathog (2014) 0.90

BpsR modulates Bordetella biofilm formation by negatively regulating the expression of the Bps polysaccharide. J Bacteriol (2011) 0.88

The eukaryotic-type serine/threonine protein kinase Stk is required for biofilm formation and virulence in Staphylococcus epidermidis. PLoS One (2011) 0.86

IsdC from Staphylococcus lugdunensis induces biofilm formation under low-iron growth conditions. Infect Immun (2014) 0.86

Staphylococcus epidermidis saeR is an effector of anaerobic growth and a mediator of acute inflammation. Infect Immun (2007) 0.86

Mechanisms of resistance to antimicrobial peptides in staphylococci. Biochim Biophys Acta (2015) 0.85

Response of corneal epithelial cells to Staphylococcus aureus. Virulence (2010) 0.84

Role of exopolysaccharide in Aggregatibacter actinomycetemcomitans-induced bone resorption in a rat model for periodontal disease. PLoS One (2015) 0.84

Tetracycline and chloramphenicol efficiency against selected biofilm forming bacteria. Curr Microbiol (2009) 0.84

Bacterial Evasion of Host Antimicrobial Peptide Defenses. Microbiol Spectr (2016) 0.82

Bacterial strategies of resistance to antimicrobial peptides. Philos Trans R Soc Lond B Biol Sci (2016) 0.82

Antivirulence properties of an antifreeze protein. Cell Rep (2014) 0.82

Antimicrobial Peptide Resistance Mechanisms of Gram-Positive Bacteria. Antibiotics (Basel) (2014) 0.82

Articles by these authors

Community-associated meticillin-resistant Staphylococcus aureus. Lancet (2010) 9.07

STAT3 mutations in the hyper-IgE syndrome. N Engl J Med (2007) 8.99

Is Panton-Valentine leukocidin the major virulence determinant in community-associated methicillin-resistant Staphylococcus aureus disease? J Infect Dis (2006) 8.17

Identification of novel cytolytic peptides as key virulence determinants for community-associated MRSA. Nat Med (2007) 7.75

Poring over pores: alpha-hemolysin and Panton-Valentine leukocidin in Staphylococcus aureus pneumonia. Nat Med (2007) 5.95

Insights into mechanisms used by Staphylococcus aureus to avoid destruction by human neutrophils. J Immunol (2005) 5.18

Epidemic community-associated methicillin-resistant Staphylococcus aureus: recent clonal expansion and diversification. Proc Natl Acad Sci U S A (2008) 4.38

Targeting of alpha-hemolysin by active or passive immunization decreases severity of USA300 skin infection in a mouse model. J Infect Dis (2010) 4.19

Panton-Valentine leukocidin is not a virulence determinant in murine models of community-associated methicillin-resistant Staphylococcus aureus disease. J Infect Dis (2008) 4.16

Evolution of virulence in epidemic community-associated methicillin-resistant Staphylococcus aureus. Proc Natl Acad Sci U S A (2009) 3.89

Autophagy-mediated reentry of Francisella tularensis into the endocytic compartment after cytoplasmic replication. Proc Natl Acad Sci U S A (2006) 3.68

Genome-wide analysis of group a streptococci reveals a mutation that modulates global phenotype and disease specificity. PLoS Pathog (2006) 3.68

The arginine catabolic mobile element and staphylococcal chromosomal cassette mec linkage: convergence of virulence and resistance in the USA300 clone of methicillin-resistant Staphylococcus aureus. J Infect Dis (2008) 3.68

Staphylococcus epidermidis infections. Microbes Infect (2002) 3.45

RNAIII-independent target gene control by the agr quorum-sensing system: insight into the evolution of virulence regulation in Staphylococcus aureus. Mol Cell (2008) 3.44

Molecular genetic anatomy of inter- and intraserotype variation in the human bacterial pathogen group A Streptococcus. Proc Natl Acad Sci U S A (2006) 3.33

A crucial role for exopolysaccharide modification in bacterial biofilm formation, immune evasion, and virulence. J Biol Chem (2004) 3.05

Polymorphonuclear leukocytes mediate Staphylococcus aureus Panton-Valentine leukocidin-induced lung inflammation and injury. Proc Natl Acad Sci U S A (2010) 3.05

Autosomal dominant and sporadic monocytopenia with susceptibility to mycobacteria, fungi, papillomaviruses, and myelodysplasia. Blood (2009) 3.00

Extracellular deoxyribonuclease made by group A Streptococcus assists pathogenesis by enhancing evasion of the innate immune response. Proc Natl Acad Sci U S A (2005) 2.84

Quorum-sensing control of biofilm factors in Staphylococcus epidermidis. J Infect Dis (2003) 2.82

The role of virulence determinants in community-associated MRSA pathogenesis. Trends Microbiol (2008) 2.78

Cytoplasmic lipid droplets are translocated into the lumen of the Chlamydia trachomatis parasitophorous vacuole. Proc Natl Acad Sci U S A (2008) 2.64

Human formyl peptide receptor 2 senses highly pathogenic Staphylococcus aureus. Cell Host Microbe (2010) 2.64

Contribution of Panton-Valentine leukocidin in community-associated methicillin-resistant Staphylococcus aureus pathogenesis. PLoS One (2008) 2.62

MRSA epidemic linked to a quickly spreading colonization and virulence determinant. Nat Med (2012) 2.61

Global changes in Staphylococcus aureus gene expression in human blood. PLoS One (2011) 2.61

Bacterial pathogens modulate an apoptosis differentiation program in human neutrophils. Proc Natl Acad Sci U S A (2003) 2.54

Transmission of Yersinia pestis from an infectious biofilm in the flea vector. J Infect Dis (2004) 2.52

Essential Staphylococcus aureus toxin export system. Nat Med (2013) 2.50

Temporal analysis of Coxiella burnetii morphological differentiation. J Bacteriol (2004) 2.47

The antimicrobial peptide-sensing system aps of Staphylococcus aureus. Mol Microbiol (2007) 2.45

How Staphylococcus aureus biofilms develop their characteristic structure. Proc Natl Acad Sci U S A (2012) 2.43

Host cell-free growth of the Q fever bacterium Coxiella burnetii. Proc Natl Acad Sci U S A (2009) 2.38

Gram-positive three-component antimicrobial peptide-sensing system. Proc Natl Acad Sci U S A (2007) 2.34

Genome-wide molecular dissection of serotype M3 group A Streptococcus strains causing two epidemics of invasive infections. Proc Natl Acad Sci U S A (2004) 2.32

Middle East respiratory syndrome coronavirus (MERS-CoV) causes transient lower respiratory tract infection in rhesus macaques. Proc Natl Acad Sci U S A (2013) 2.29

Progress toward characterization of the group A Streptococcus metagenome: complete genome sequence of a macrolide-resistant serotype M6 strain. J Infect Dis (2004) 2.29

Staphylococcus quorum sensing in biofilm formation and infection. Int J Med Microbiol (2006) 2.25

Apolipoprotein B Is an innate barrier against invasive Staphylococcus aureus infection. Cell Host Microbe (2008) 2.20

Comparative analysis of USA300 virulence determinants in a rabbit model of skin and soft tissue infection. J Infect Dis (2011) 2.19

In vitro serial passage of Staphylococcus aureus: changes in physiology, virulence factor production, and agr nucleotide sequence. J Bacteriol (2002) 2.19

Neutrophils in innate host defense against Staphylococcus aureus infections. Semin Immunopathol (2011) 2.17

Selective antimicrobial action is provided by phenol-soluble modulins derived from Staphylococcus epidermidis, a normal resident of the skin. J Invest Dermatol (2010) 2.13

Comparative analysis of virulence and toxin expression of global community-associated methicillin-resistant Staphylococcus aureus strains. J Infect Dis (2010) 2.13

The early phagosomal stage of Francisella tularensis determines optimal phagosomal escape and Francisella pathogenicity island protein expression. Infect Immun (2008) 2.12

A point mutation in the agr locus rather than expression of the Panton-Valentine leukocidin caused previously reported phenotypes in Staphylococcus aureus pneumonia and gene regulation. J Infect Dis (2009) 2.12

Genomewide analysis of gene expression in Staphylococcus epidermidis biofilms: insights into the pathophysiology of S. epidermidis biofilms and the role of phenol-soluble modulins in formation of biofilms. J Infect Dis (2004) 2.09

Host defense and pathogenesis in Staphylococcus aureus infections. Infect Dis Clin North Am (2009) 2.01

Intracellular biology and virulence determinants of Francisella tularensis revealed by transcriptional profiling inside macrophages. Cell Microbiol (2009) 2.00

Identification of a highly transmissible animal-independent Staphylococcus aureus ST398 clone with distinct genomic and cell adhesion properties. MBio (2012) 2.00

Staphylococcus epidermidis surfactant peptides promote biofilm maturation and dissemination of biofilm-associated infection in mice. J Clin Invest (2010) 2.00

Genome-wide protective response used by group A Streptococcus to evade destruction by human polymorphonuclear leukocytes. Proc Natl Acad Sci U S A (2003) 1.99

Neutrophil microbicides induce a pathogen survival response in community-associated methicillin-resistant Staphylococcus aureus. J Immunol (2008) 1.97