Published in Cancer Res on February 15, 2004
Mechanisms of human papillomavirus-induced oncogenesis. J Virol (2004) 3.95
The human papillomavirus E7 oncoprotein. Virology (2008) 2.32
The nature of telomere fusion and a definition of the critical telomere length in human cells. Genes Dev (2007) 1.88
Oncogenic activities of human papillomaviruses. Virus Res (2009) 1.60
Genome-wide analysis of HPV integration in human cancers reveals recurrent, focal genomic instability. Genome Res (2013) 1.47
Molecular mechanisms of human papillomavirus-induced carcinogenesis. Public Health Genomics (2009) 1.45
Characterization of HPV and host genome interactions in primary head and neck cancers. Proc Natl Acad Sci U S A (2014) 1.37
Mechanism of genomic instability in cells infected with the high-risk human papillomaviruses. PLoS Pathog (2009) 1.34
Epithelial cell responses to infection with human papillomavirus. Clin Microbiol Rev (2012) 1.33
Selection of cervical keratinocytes containing integrated HPV16 associates with episome loss and an endogenous antiviral response. Proc Natl Acad Sci U S A (2006) 1.31
Integrative genomics analysis of chromosome 5p gain in cervical cancer reveals target over-expressed genes, including Drosha. Mol Cancer (2008) 1.29
Genomic instability of the host cell induced by the human papillomavirus replication machinery. EMBO J (2007) 1.27
Evaluation of a commercialized in situ hybridization assay for detecting human papillomavirus DNA in tissue specimens from patients with cervical intraepithelial neoplasia and cervical carcinoma. J Clin Microbiol (2007) 1.22
In vitro progression of human papillomavirus 16 episome-associated cervical neoplasia displays fundamental similarities to integrant-associated carcinogenesis. Cancer Res (2010) 1.10
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Human papillomavirus molecular biology and disease association. Rev Med Virol (2015) 1.09
Dynamic localization of the human papillomavirus type 11 origin binding protein E2 through mitosis while in association with the spindle apparatus. J Virol (2006) 1.04
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Development of a cellular assay system to study the genome replication of high- and low-risk mucosal and cutaneous human papillomaviruses. J Virol (2011) 0.96
Critical evaluation of HPV16 gene copy number quantification by SYBR green PCR. BMC Biotechnol (2008) 0.93
Viruses and human cancers: a long road of discovery of molecular paradigms. Clin Microbiol Rev (2014) 0.93
Papillomavirus-mediated neoplastic progression is associated with reciprocal changes in JAGGED1 and manic fringe expression linked to notch activation. J Virol (2004) 0.93
LIN28 Expression in malignant germ cell tumors downregulates let-7 and increases oncogene levels. Cancer Res (2013) 0.92
The invisible enemy - how human papillomaviruses avoid recognition and clearance by the host immune system. Open Virol J (2012) 0.91
Oncostatin M receptor is a novel therapeutic target in cervical squamous cell carcinoma. J Pathol (2014) 0.91
Detection of oncogenic virus genomes and gene products in lung carcinoma. Br J Cancer (2005) 0.90
Lack of correlation between predicted and actual off-target effects of short-interfering RNAs targeting the human papillomavirus type 16 E7 oncogene. Br J Cancer (2013) 0.88
Genomic imbalances in 70 snap-frozen cervical squamous intraepithelial lesions: associations with lesion grade, state of the HPV16 E2 gene and clinical outcome. Br J Cancer (2004) 0.86
High-resolution genomic profiling of human papillomavirus-associated vulval neoplasia. Br J Cancer (2010) 0.85
Effective formation of the segregation-competent complex determines successful partitioning of the bovine papillomavirus genome during cell division. J Virol (2010) 0.81
HPV16 E5 and KGFR/FGFR2b interplay in differentiating epithelial cells. Oncotarget (2013) 0.81
Human papillomavirus and gastrointestinal cancer: A review. World J Gastroenterol (2016) 0.80
Virus transcript levels and cell growth rates after naturally occurring HPV16 integration events in basal cervical keratinocytes. J Pathol (2014) 0.80
Expression of HPV16 E5 down-modulates the TGFbeta signaling pathway. Mol Cancer (2013) 0.80
Historical review of the causes of cancer. World J Clin Oncol (2016) 0.79
Viruses, Other Pathogenic Microorganisms and Esophageal Cancer. Gastrointest Tumors (2015) 0.79
Human papillomavirus induced transformation in cervical and head and neck cancers. Cancers (Basel) (2014) 0.79
Tumourigenesis driven by the human papillomavirus type 16 Asian-American e6 variant in a three-dimensional keratinocyte model. PLoS One (2014) 0.78
Lipoprotein lipase is frequently overexpressed or translocated in cervical squamous cell carcinoma and promotes invasiveness through the non-catalytic C terminus. Br J Cancer (2012) 0.78
Human papillomavirus infections: warts or cancer? Cold Spring Harb Perspect Biol (2013) 0.78
HPV16 oncogene expression levels during early cervical carcinogenesis are determined by the balance of epigenetic chromatin modifications at the integrated virus genome. Oncogene (2016) 0.78
Sequence variation of human papillomavirus type 16 and measurement of viral integration by quantitative PCR. J Clin Microbiol (2008) 0.78
HPV16 E5 deregulates the autophagic process in human keratinocytes. Oncotarget (2015) 0.77
Evidence of disrupted high-risk human papillomavirus DNA in morphologically normal cervices of older women. Sci Rep (2016) 0.76
Genomic Integration of High-Risk HPV Alters Gene Expression in Oropharyngeal Squamous Cell Carcinoma. Mol Cancer Res (2016) 0.75
Next generation sequencing and its applications in HPV-associated cancers. Oncotarget (2016) 0.75
Expression of the p53 target Wig-1 is associated with HPV status and patient survival in cervical carcinoma. PLoS One (2014) 0.75
Identification of host transcriptional networks showing concentration-dependent regulation by HPV16 E6 and E7 proteins in basal cervical squamous epithelial cells. Sci Rep (2016) 0.75
Comparative analysis of HPV16 gene expression profiles in cervical and in oropharyngeal squamous cell carcinoma. Oncotarget (2017) 0.75
Molecular mechanisms of HPV mediated neoplastic progression. Infect Agent Cancer (2016) 0.75
miR-484 suppresses proliferation and epithelial-mesenchymal transition by targeting ZEB1 and SMAD2 in cervical cancer cells. Cancer Cell Int (2017) 0.75
Increasing response rates to postal questionnaires: systematic review. BMJ (2002) 19.50
Methods to increase response to postal and electronic questionnaires. Cochrane Database Syst Rev (2009) 10.85
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial. Lancet (2011) 9.31
Smoking cessation support delivered via mobile phone text messaging (txt2stop): a single-blind, randomised trial. Lancet (2011) 8.19
What influences recruitment to randomised controlled trials? A review of trials funded by two UK funding agencies. Trials (2006) 7.32
Where is the evidence that animal research benefits humans? BMJ (2004) 5.99
Cloning and characterization of the common fragile site FRA6F harboring a replicative senescence gene and frequently deleted in human tumors. Oncogene (2002) 5.40
Identification of randomized controlled trials in systematic reviews: accuracy and reliability of screening records. Stat Med (2002) 5.35
Comparison of treatment effects between animal experiments and clinical trials: systematic review. BMJ (2006) 5.05
Interventions to improve water quality for preventing diarrhoea: systematic review and meta-analysis. BMJ (2007) 4.79
Effect of consent rituals on mortality in emergency care research. Lancet (2011) 4.74
Public health benefits of strategies to reduce greenhouse-gas emissions: urban land transport. Lancet (2009) 4.60
Predicting outcome after traumatic brain injury: practical prognostic models based on large cohort of international patients. BMJ (2008) 4.60
Predicting outcome after traumatic brain injury: development and international validation of prognostic scores based on admission characteristics. PLoS Med (2008) 4.60
Final results of MRC CRASH, a randomised placebo-controlled trial of intravenous corticosteroid in adults with head injury-outcomes at 6 months. Lancet (2005) 3.70
Public health benefits of strategies to reduce greenhouse-gas emissions: overview and implications for policy makers. Lancet (2009) 3.51
Development of a cross-platform biomarker signature to detect renal transplant tolerance in humans. J Clin Invest (2010) 3.41
Skp2 inhibits FOXO1 in tumor suppression through ubiquitin-mediated degradation. Proc Natl Acad Sci U S A (2005) 3.16
Mutations in DNMT1 cause hereditary sensory neuropathy with dementia and hearing loss. Nat Genet (2011) 3.16
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis. BMJ (2012) 3.05
Patterns of gene expression in different histotypes of epithelial ovarian cancer correlate with those in normal fallopian tube, endometrium, and colon. Clin Cancer Res (2005) 2.98
Constitutive and induced expression of DC-SIGN on dendritic cell and macrophage subpopulations in situ and in vitro. J Leukoc Biol (2002) 2.93
Population adiposity and climate change. Int J Epidemiol (2009) 2.92
Non-vigorous physical activity and all-cause mortality: systematic review and meta-analysis of cohort studies. Int J Epidemiol (2010) 2.90
Deaths from injury in children and employment status in family: analysis of trends in class specific death rates. BMJ (2006) 2.87
Incidence of fires and related injuries after giving out free smoke alarms: cluster randomised controlled trial. BMJ (2002) 2.77
Selective reporting in clinical trials: analysis of trial protocols accepted by The Lancet. Lancet (2008) 2.76
Safety education of pedestrians for injury prevention: a systematic review of randomised controlled trials. BMJ (2002) 2.68
A role for common fragile site induction in amplification of human oncogenes. Cancer Cell (2002) 2.63
Effect of increasing active travel in urban England and Wales on costs to the National Health Service. Lancet (2012) 2.63
War on the roads. BMJ (2002) 2.60
The biology and life-cycle of human papillomaviruses. Vaccine (2012) 2.53
Aberrant succination of proteins in fumarate hydratase-deficient mice and HLRCC patients is a robust biomarker of mutation status. J Pathol (2011) 2.45
Alterations in the common fragile site gene Parkin in ovarian and other cancers. Oncogene (2003) 2.44
Reducing the carbon footprint of medical conferences. BMJ (2007) 2.42
Loss of HSulf-1 up-regulates heparin-binding growth factor signaling in cancer. J Biol Chem (2003) 2.40
Patient safety requires a new way to publish clinical trials. PLoS Clin Trials (2006) 2.35
Colloids versus crystalloids for fluid resuscitation in critically ill patients. Cochrane Database Syst Rev (2013) 2.32
Prognosis research strategy (PROGRESS) 1: a framework for researching clinical outcomes. BMJ (2013) 2.31
Walking, cycling and transport safety: an analysis of child road deaths. J R Soc Med (2006) 2.30
Congestion charging and the walking classes. BMJ (2003) 2.30
Systematic review of prognostic models in traumatic brain injury. BMC Med Inform Decis Mak (2006) 2.29
Gene expression profiles predict early relapse in ovarian cancer after platinum-paclitaxel chemotherapy. Clin Cancer Res (2005) 2.29
Energy and transport. Lancet (2007) 2.23
Histological changes in HCV antibody-positive, HCV RNA-negative subjects suggest persistent virus infection. Hepatology (2008) 2.21
Malignant pheochromocytoma: current status and initiatives for future progress. Endocr Relat Cancer (2004) 2.20
Mutational spectrum of beta-catenin, AXIN1, and AXIN2 in hepatocellular carcinomas and hepatoblastomas. Oncogene (2002) 2.16
Public health benefits of strategies to reduce greenhouse-gas emissions: food and agriculture. Lancet (2009) 2.12
3' tag digital gene expression profiling of human brain and universal reference RNA using Illumina Genome Analyzer. BMC Genomics (2009) 2.12
Compromised lymphocytes infiltrate hepatocellular carcinoma: the role of T-regulatory cells. Hepatology (2005) 2.04
Are these data real? Statistical methods for the detection of data fabrication in clinical trials. BMJ (2005) 2.04
Saddam Hussein's medical examination should not have been broadcast: images were designed to humiliate. BMJ (2004) 2.03
Hypothermia for traumatic head injury. Cochrane Database Syst Rev (2009) 2.03
Building a semantically annotated corpus of clinical texts. J Biomed Inform (2009) 2.03
Generation of "neoheparin" from E. coli K5 capsular polysaccharide. J Med Chem (2005) 2.03
Long, abundantly expressed non-coding transcripts are altered in cancer. Hum Mol Genet (2007) 2.00
Common fragile sites are preferential targets for HPV16 integrations in cervical tumors. Oncogene (2003) 2.00
Mutations in CHEK2 associated with prostate cancer risk. Am J Hum Genet (2003) 1.96
Genome-wide analysis reveals recurrent structural abnormalities of TP63 and other p53-related genes in peripheral T-cell lymphomas. Blood (2012) 1.96
hSulf1 Sulfatase promotes apoptosis of hepatocellular cancer cells by decreasing heparin-binding growth factor signaling. Gastroenterology (2004) 1.95
Discovery of recurrent t(6;7)(p25.3;q32.3) translocations in ALK-negative anaplastic large cell lymphomas by massively parallel genomic sequencing. Blood (2010) 1.90
Follow-up by mail in clinical trials: does questionnaire length matter? Control Clin Trials (2004) 1.88
Carbon cost of pragmatic randomised controlled trials: retrospective analysis of sample of trials. BMJ (2009) 1.86
Tumor transcriptome sequencing reveals allelic expression imbalances associated with copy number alterations. PLoS One (2010) 1.85
Policies for accelerating access to clean energy, improving health, advancing development, and mitigating climate change. Lancet (2007) 1.84
Topical application of tranexamic acid for the reduction of bleeding. Cochrane Database Syst Rev (2013) 1.83
HSulf-1 modulates HGF-mediated tumor cell invasion and signaling in head and neck squamous carcinoma. Oncogene (2004) 1.82
Organization of human papillomavirus productive cycle during neoplastic progression provides a basis for selection of diagnostic markers. J Virol (2003) 1.79
The weight of nations: an estimation of adult human biomass. BMC Public Health (2012) 1.78
Prevalence of working smoke alarms in local authority inner city housing: randomised controlled trial. BMJ (2002) 1.77
The CLEF corpus: semantic annotation of clinical text. AMIA Annu Symp Proc (2007) 1.76
Palladin mutation causes familial pancreatic cancer and suggests a new cancer mechanism. PLoS Med (2006) 1.73
Systematic reviews of animal experiments. Lancet (2002) 1.70
Tumour lymphocytic infiltrate and recurrence of hepatocellular carcinoma following liver transplantation. J Hepatol (2006) 1.69
Dysregulated microRNAs and their predicted targets associated with endometrioid endometrial adenocarcinoma in Hong Kong women. Int J Cancer (2009) 1.68
Colorectal cancer screening: prospects for molecular stool analysis. Nat Rev Cancer (2005) 1.64
HPV & head and neck cancer: a descriptive update. Head Neck Oncol (2009) 1.60
Meta-analysis of randomised trials of monetary incentives and response to mailed questionnaires. J Epidemiol Community Health (2005) 1.60
Malignant germ cell tumors display common microRNA profiles resulting in global changes in expression of messenger RNA targets. Cancer Res (2010) 1.59
Mannitol for acute traumatic brain injury. Cochrane Database Syst Rev (2013) 1.59
AGR2, an androgen-inducible secretory protein overexpressed in prostate cancer. Genes Chromosomes Cancer (2005) 1.58
Cost-effectiveness analysis of administering tranexamic acid to bleeding trauma patients using evidence from the CRASH-2 trial. PLoS One (2011) 1.56
MANF: a new mesencephalic, astrocyte-derived neurotrophic factor with selectivity for dopaminergic neurons. J Mol Neurosci (2003) 1.54
FUS/ERG gene fusions in Ewing's tumors. Cancer Res (2003) 1.50
Geminin is essential to prevent endoreduplication and to form pluripotent cells during mammalian development. Genes Dev (2006) 1.49
A candidate tumor suppressor HtrA1 is downregulated in ovarian cancer. Oncogene (2004) 1.47
Transport policy is food policy. Lancet (2008) 1.45
Tranexamic acid for reducing mortality in emergency and urgent surgery. Cochrane Database Syst Rev (2013) 1.45
The CRASH-2 trial of an antifibrinolytic agent in traumatic haemorrhage: an international collaboration. Indian J Med Res (2007) 1.45
The effect of scientific misconduct on the results of clinical trials: a Delphi survey. Contemp Clin Trials (2005) 1.45
Patient outcome after traumatic brain injury in high-, middle- and low-income countries: analysis of data on 8927 patients in 46 countries. Int J Epidemiol (2008) 1.45
Tumor recurrence following liver transplantation for hepatocellular carcinoma: role of tumor proliferation status. Liver Transpl (2010) 1.44
Cell-cycle-dependent regulation of DNA replication and its relevance to cancer pathology. J Pathol (2005) 1.44
The tens of thousands of lives saved by randomized clinical trials in critical care. Intensive Care Med (2014) 1.44
The BRAIN TRIAL: a randomised, placebo controlled trial of a Bradykinin B2 receptor antagonist (Anatibant) in patients with traumatic brain injury. Trials (2009) 1.43
New GMC guidance takes a major, ethically flawed, backward step. BMJ (2013) 1.43
Control of DNA replication and its potential clinical exploitation. Nat Rev Cancer (2005) 1.42