| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Effect of intensive versus standard lipid-lowering treatment with atorvastatin on the progression of calcified coronary atherosclerosis over 12 months: a multicenter, randomized, double-blind trial.
|
Circulation
|
2006
|
3.99
|
|
2
|
Assessment of clinically silent atherosclerotic disease and established and novel risk factors for predicting myocardial infarction and cardiac death in healthy middle-aged subjects: rationale and design of the Heinz Nixdorf RECALL Study. Risk Factors, Evaluation of Coronary Calcium and Lifestyle.
|
Am Heart J
|
2002
|
3.35
|
|
3
|
G-protein beta 3 subunit 825 CC genotype is associated with unexplained (functional) dyspepsia.
|
Gastroenterology
|
2004
|
2.24
|
|
4
|
Melanocortin-4 receptor gene variant I103 is negatively associated with obesity.
|
Am J Hum Genet
|
2004
|
2.17
|
|
5
|
Association of a novel regulatory polymorphism (-938C>A) in the BCL2 gene promoter with disease progression and survival in chronic lymphocytic leukemia.
|
Blood
|
2006
|
1.89
|
|
6
|
Prediction of successful weight reduction under sibutramine therapy through genotyping of the G-protein beta3 subunit gene (GNB3) C825T polymorphism.
|
Pharmacogenetics
|
2003
|
1.61
|
|
7
|
Characterization of the GNAQ promoter and association of increased Gq expression with cardiac hypertrophy in humans.
|
Eur Heart J
|
2008
|
1.52
|
|
8
|
Gender-dependent association of the GNAS1 T393C polymorphism with early aseptic loosening after total hip arthroplasty.
|
J Orthop Res
|
2008
|
1.44
|
|
9
|
PCR-amplification of GC-rich regions: 'slowdown PCR'.
|
Nat Protoc
|
2008
|
1.25
|
|
10
|
Alemtuzumab induces enhanced apoptosis in vitro in B-cells from patients with chronic lymphocytic leukemia by antibody-dependent cellular cytotoxicity.
|
Eur J Pharmacol
|
2005
|
1.16
|
|
11
|
Successful amplification of extremely GC-rich promoter regions using a novel 'slowdown PCR' technique.
|
Pharmacogenetics
|
2003
|
1.14
|
|
12
|
Comparison of manual and automated nucleic acid extraction from whole-blood samples.
|
J Clin Lab Anal
|
2007
|
1.10
|
|
13
|
Risk factors for thrombus formation on the Amplatzer Cardiac Plug after left atrial appendage occlusion.
|
JACC Cardiovasc Interv
|
2013
|
1.06
|
|
14
|
The IKZF3 (Aiolos) transcription factor is highly upregulated and inversely correlated with clinical progression in chronic lymphocytic leukaemia.
|
Br J Haematol
|
2008
|
1.03
|
|
15
|
The AA genotype of the regulatory BCL2 promoter polymorphism ( 938C>A) is associated with a favorable outcome in lymph node negative invasive breast cancer patients.
|
Clin Cancer Res
|
2007
|
1.02
|
|
16
|
The T393C polymorphism of the G alpha s gene (GNAS1) is a novel prognostic marker in bladder cancer.
|
Cancer Epidemiol Biomarkers Prev
|
2005
|
1.00
|
|
17
|
Insertion/deletion polymorphism in the promoter of NFKB1 influences severity but not mortality of acute respiratory distress syndrome.
|
Intensive Care Med
|
2007
|
0.99
|
|
18
|
The NFKB1 promoter polymorphism (-94ins/delATTG) alters nuclear translocation of NF-κB1 in monocytes after lipopolysaccharide stimulation and is associated with increased mortality in sepsis.
|
Anesthesiology
|
2013
|
0.99
|
|
19
|
Quantification of allele-specific G-protein beta3 subunit mRNA transcripts in different human cells and tissues by Pyrosequencing.
|
Eur J Hum Genet
|
2005
|
0.99
|
|
20
|
The GNAS1 T393C polymorphism is associated with disease progression and survival in chronic lymphocytic leukemia.
|
Clin Cancer Res
|
2006
|
0.98
|
|
21
|
GNAS1 T393C polymorphism and survival in patients with sporadic colorectal cancer.
|
Clin Cancer Res
|
2005
|
0.96
|
|
22
|
A variant allele of Growth Factor Independence 1 (GFI1) is associated with acute myeloid leukemia.
|
Blood
|
2010
|
0.96
|
|
23
|
Regulatory BCL2 promoter polymorphism (-938C>A) is associated with adverse outcome in patients with prostate carcinoma.
|
Int J Cancer
|
2011
|
0.95
|
|
24
|
Identification and ethnic distribution of major haplotypes in the gene GNB3 encoding the G-protein beta3 subunit.
|
Pharmacogenetics
|
2002
|
0.95
|
|
25
|
The GNAS1 T393C polymorphism predicts survival in patients with clear cell renal cell carcinoma.
|
Clin Cancer Res
|
2006
|
0.94
|
|
26
|
Expression analysis and potential functional role of the CXCR4 chemokine receptor in bladder cancer.
|
Eur Urol
|
2005
|
0.93
|
|
27
|
The GNB3 C825T polymorphism as a pharmacogenetic marker in the treatment of hypertension, obesity, and depression.
|
Pharmacogenet Genomics
|
2011
|
0.92
|
|
28
|
The T393C polymorphism in the gene GNAS1 of G protein is associated with survival of patients with invasive breast carcinoma.
|
Breast Cancer Res Treat
|
2006
|
0.91
|
|
29
|
Prognostic assessment of three single-nucleotide polymorphisms (GNB3 825C>T, BCL2-938C>A, MCL1-386C>G) in extrahepatic cholangiocarcinoma.
|
Cancer Invest
|
2010
|
0.91
|
|
30
|
Overall and relapse-free survival in oropharyngeal and hypopharyngeal squamous cell carcinoma are associated with genotypes of T393C polymorphism of the GNAS1 gene.
|
Clin Cancer Res
|
2008
|
0.91
|
|
31
|
A novel functional haplotype in the human GNAS gene alters Galphas expression, responsiveness to beta-adrenoceptor stimulation, and peri-operative cardiac performance.
|
Eur Heart J
|
2009
|
0.90
|
|
32
|
Aquaporin 1 (AQP1) expression is a novel characteristic feature of a particularly aggressive subgroup of basal-like breast carcinomas.
|
Breast Cancer Res Treat
|
2009
|
0.89
|
|
33
|
Decreased expression of miR-133a but not of miR-1 is associated with signs of heart failure in patients undergoing coronary bypass surgery.
|
Cardiology
|
2013
|
0.89
|
|
34
|
Binge eating as a phenotype of melanocortin 4 receptor gene mutations.
|
N Engl J Med
|
2003
|
0.89
|
|
35
|
Interaction of Gbeta3s, a splice variant of the G-protein Gbeta3, with Ggamma- and Galpha-proteins.
|
Cell Signal
|
2003
|
0.88
|
|
36
|
No association of the NFKB1 insertion/deletion promoter polymorphism with survival in colorectal and renal cell carcinoma as well as disease progression in B-cell chronic lymphocytic leukemia.
|
Pharmacogenet Genomics
|
2006
|
0.88
|
|
37
|
Identification and characterization of G beta 3s2, a novel splice variant of the G-protein beta 3 subunit.
|
Biochem J
|
2003
|
0.88
|
|
38
|
Association of the AA genotype of the BCL2 (-938C>A) promoter polymorphism with better survival in ovarian cancer.
|
Int J Biol Markers
|
2010
|
0.87
|
|
39
|
Enhanced vasoconstriction to endothelin-1, angiotensin II and noradrenaline in carriers of the GNB3 825T allele in the skin microcirculation.
|
Pharmacogenetics
|
2002
|
0.87
|
|
40
|
G-protein beta3-subunit gene 825T allele and hypertension: a longitudinal study in young grade I hypertensives.
|
Hypertension
|
2003
|
0.87
|
|
41
|
Correlation of aquaporin-1 water channel protein expression with tumor angiogenesis in human astrocytoma.
|
Anticancer Res
|
2013
|
0.87
|
|
42
|
GNAS1 T393C polymorphism is associated with clinical course in patients with intrahepatic cholangiocarcinoma.
|
Neoplasia
|
2007
|
0.87
|
|
43
|
A novel-1364A/C aquaporin 5 gene promoter polymorphism influences the responses to salt loading of the renin-angiotensin-aldosterone system and of blood pressure in young healthy men.
|
Basic Res Cardiol
|
2008
|
0.86
|
|
44
|
Factor V Leiden mutation is associated with improved 30-day survival in patients with acute respiratory distress syndrome.
|
Crit Care Med
|
2008
|
0.86
|
|
45
|
Nutrigenomics: where are we with genetic and epigenetic markers for disposition and susceptibility?
|
Nutr Rev
|
2010
|
0.85
|
|
46
|
Role of G protein beta3 subunit C825T and HLA class II polymorphisms in the immune response after HBV vaccination.
|
Virology
|
2002
|
0.85
|
|
47
|
BCL2-938C>A polymorphism and disease progression in chronic lymphocytic leukemia.
|
Leuk Lymphoma
|
2009
|
0.85
|
|
48
|
A novel promoter polymorphism in the human gene GNAS affects binding of transcription factor upstream stimulatory factor 1, Galphas protein expression and body weight regulation.
|
Pharmacogenet Genomics
|
2008
|
0.85
|
|
49
|
Quantification of G protein Gaalphas subunit splice variants in different human tissues and cells using pyrosequencing.
|
Gene Expr
|
2005
|
0.84
|
|
50
|
Molecular basis of functional gastrointestinal disorders.
|
Best Pract Res Clin Gastroenterol
|
2004
|
0.84
|
|
51
|
The GNAS1 T393C polymorphism predicts survival in patients with advanced squamous cell carcinoma of the larynx.
|
Laryngoscope
|
2008
|
0.84
|
|
52
|
Association of the CC genotype of the regulatory BCL2 promoter polymorphism (-938C>A) with better 2-year survival in patients with glioblastoma multiforme.
|
J Neurosurg
|
2011
|
0.84
|
|
53
|
A 3'UTR polymorphism modulates mRNA stability of the oncogene and drug target Polo-like Kinase 1.
|
Mol Cancer
|
2014
|
0.82
|
|
54
|
Cooperative effect of GNB3 825C>T and GPIIIa PI(A) polymorphisms in enhanced platelet aggregation.
|
Thromb Res
|
2003
|
0.82
|
|
55
|
The prevalence of the c-kit exon 10 variant, M541L, in aggressive fibromatosis does not differ from the general population.
|
J Clin Pathol
|
2011
|
0.82
|
|
56
|
Signal transduction of somatostatin in human B lymphoblasts.
|
Am J Physiol Cell Physiol
|
2002
|
0.82
|
|
57
|
A novel aspect of GNAS imprinting: higher maternal expression of Gαs in human lymphoblasts, peripheral blood mononuclear cells, mammary adipose tissue, and heart.
|
Mol Cell Endocrinol
|
2011
|
0.82
|
|
58
|
The human G protein beta4 subunit: gene structure, expression, Ggamma and effector interaction.
|
FEBS Lett
|
2003
|
0.81
|
|
59
|
Aquaporin 5 gene promoter--1364A/C polymorphism associated with 30-day survival in severe sepsis.
|
Anesthesiology
|
2011
|
0.81
|
|
60
|
Aquaporin 1 and 5 expression evoked by the β2 adrenoreceptor agonist terbutaline and lipopolysaccharide in mice and in the human monocytic cell line THP-1 is differentially regulated.
|
Shock
|
2013
|
0.81
|
|
61
|
Effects of systemic endothelin A receptor antagonism in various vascular beds in men: in vivo interactions of the major blood pressure-regulating systems and associations with the GNB3 C825T polymorphism.
|
Clin Pharmacol Ther
|
2004
|
0.81
|
|
62
|
Prognostic relevance of the AQP5 -1364C>A polymorphism in primary breast cancer.
|
Mol Med Rep
|
2011
|
0.81
|
|
63
|
Association study of the G-protein beta3 subunit C825T polymorphism with disease progression in patients with bladder cancer.
|
World J Urol
|
2005
|
0.80
|
|
64
|
The angiotensin II receptor antagonist valsartan inhibits endothelin 1-induced vasoconstriction in the skin microcirculation in humans in vivo: influence of the G-protein beta3 subunit (GNB3) C825T polymorphism.
|
Clin Pharmacol Ther
|
2006
|
0.80
|
|
65
|
Expression of aquaporin 5 and the AQP5 polymorphism A(-1364)C in association with peritumoral brain edema in meningioma patients.
|
J Neurooncol
|
2013
|
0.80
|
|
66
|
Characterization of the splice variant Gbeta3v of the human G-protein Gbeta3 subunit.
|
Biochim Biophys Acta
|
2003
|
0.80
|
|
67
|
1513A/C polymorphism in the P2X7 receptor gene in chronic lymphocytic leukemia: absence of correlation with clinical outcome.
|
Eur J Haematol
|
2004
|
0.80
|
|
68
|
Effects of lifestyle modification on the progression of coronary atherosclerosis, autonomic function, and angina--the role of GNB3 C825T polymorphism.
|
Am Heart J
|
2006
|
0.80
|
|
69
|
Association of the GNAS1 T393C polymorphism with tumor stage and survival in gastric cancer.
|
World J Gastroenterol
|
2009
|
0.80
|
|
70
|
G protein beta3 subunit 825T allele is associated with depression in young, healthy subjects.
|
Neuroreport
|
2003
|
0.80
|
|
71
|
SNPs in genes encoding G proteins in pharmacogenetics.
|
Pharmacogenomics
|
2011
|
0.80
|
|
72
|
The CC genotype of the GNAS T393C polymorphism is associated with obesity and insulin resistance in women with polycystic ovary syndrome.
|
Eur J Endocrinol
|
2006
|
0.80
|
|
73
|
The G-Allele of the PSMA6-8C>G polymorphism is associated with poor outcome in multiple myeloma independently of circulating proteasome serum levels.
|
Eur J Haematol
|
2010
|
0.79
|
|
74
|
GNB3 C825T polymorphism and response to interferon-alfa/ribavirin treatment in patients with hepatitis C virus genotype 1 (HCV-1) infection.
|
J Hepatol
|
2005
|
0.79
|
|
75
|
Effect of the C825T polymorphism of the G protein beta 3 subunit on the systolic blood pressure-lowering effect of clonidine in young, healthy male subjects.
|
Clin Pharmacol Ther
|
2003
|
0.79
|
|
76
|
Association study of the G-protein beta3 subunit C825T polymorphism with disease progression an overall survival in patients with head and neck squamous cell carcinoma.
|
Cancer Epidemiol Biomarkers Prev
|
2008
|
0.78
|
|
77
|
Different genotype distribution of the GNB3 C825T polymorphism of the G protein beta3 subunit in adenomas and differentiated thyroid carcinomas of follicular cell origin.
|
J Pathol
|
2005
|
0.78
|
|
78
|
Polymorphisms associated with ventricular tachyarrhythmias: rationale, design, and endpoints of the 'diagnostic data influence on disease management and relation of genomics to ventricular tachyarrhythmias in implantable cardioverter/defibrillator patients (DISCOVERY)' study.
|
Europace
|
2010
|
0.78
|
|
79
|
Homozygous GNAS 393C-allele carriers with locally advanced esophageal cancer fail to benefit from platinum-based preoperative chemoradiotherapy.
|
Ann Surg Oncol
|
2014
|
0.78
|
|
80
|
ACE gene I/D and NOS3 G894T polymorphisms and response to sildenafil in men with erectile dysfunction.
|
Urology
|
2003
|
0.78
|
|
81
|
The Arg16Gly-β(2)-adrenoceptor single nucleotide polymorphism: exercise capacity and survival in patients with end-stage heart failure.
|
Naunyn Schmiedebergs Arch Pharmacol
|
2010
|
0.78
|
|
82
|
The functional Aquaporin 1 -783G/C-polymorphism is associated with survival in patients with glioblastoma multiforme.
|
J Surg Oncol
|
2013
|
0.78
|
|
83
|
A functional GNAQ promoter haplotype is associated with altered Gq expression and with insulin resistance and obesity in women with polycystic ovary syndrome.
|
Pharmacogenet Genomics
|
2010
|
0.78
|
|
84
|
Insulin-mediated venodilation is impaired in young, healthy carriers of the 825T allele of the G-protein beta3 subunit gene (GNB3).
|
Clin Pharmacol Ther
|
2005
|
0.78
|
|
85
|
DNA repair gene XRCC1 polymorphisms and outcome of renal cell carcinoma in Caucasian patients.
|
Anticancer Res
|
2009
|
0.78
|
|
86
|
The haplotype of two FSHR polymorphisms in ovarian cancer--a potential role of ethnology in risk modification.
|
Gynecol Oncol
|
2009
|
0.78
|
|
87
|
The I1-imidazoline agonist moxonidine decreases sympathetic tone under physical and mental stress.
|
Br J Clin Pharmacol
|
2004
|
0.77
|
|
88
|
The CC genotype of the C825T polymorphism of the G protein beta3 gene (GNB3) is associated with a high relapse rate in patients with chronic lymphocytic leukaemia.
|
Leuk Lymphoma
|
2003
|
0.77
|
|
89
|
Venous response to nitroglycerin is enhanced in young, healthy carriers of the 825T allele of the G protein beta3 subunit gene (GNB3).
|
Clin Pharmacol Ther
|
2003
|
0.77
|
|
90
|
Better identification of patients who benefit from implantable cardioverter defibrillators by genotyping the G protein beta3 subunit (GNB3) C825T polymorphism.
|
Basic Res Cardiol
|
2006
|
0.77
|
|
91
|
FCRL2 mRNA expression is inversely associated with clinical progression in chronic lymphocytic leukemia.
|
Eur J Haematol
|
2009
|
0.77
|
|
92
|
Effects of the G protein beta 3-subunit gene C825T polymorphism: should hypotheses regarding the molecular mechanisms underlying enhanced G protein activation be revised? Focus on "A splice variant of the G protein beta 3-subunit implicated in disease states does not modulate ion channels".
|
Physiol Genomics
|
2003
|
0.77
|
|
93
|
The AA genotype of a L1C G842A polymorphism is associated with an increased risk for ovarian cancer.
|
Anticancer Res
|
2009
|
0.76
|
|
94
|
Characterization of intron-1 haplotypes of the G protein beta 4 subunit gene--association with survival and progression in patients with urothelial bladder carcinoma.
|
Pharmacogenet Genomics
|
2008
|
0.76
|
|
95
|
Hunger and mood during extended fasting are dependent on the GNB3 C825T polymorphism.
|
Ann Nutr Metab
|
2009
|
0.76
|
|
96
|
Role of the eNOS Glu298Asp variant on the GNB3825T allele dependent determination of alpha-adrenergic coronary constriction.
|
Pharmacogenetics
|
2003
|
0.76
|
|
97
|
Association of the GNB3 825T-allele with better survival in patients with glioblastoma multiforme.
|
J Cancer Res Clin Oncol
|
2010
|
0.76
|
|
98
|
Posttonsillectomy hemorrhage: blame on surgeons or genes?
|
Laryngoscope
|
2010
|
0.76
|
|
99
|
Genetic risk factors for erectile dysfunction and genetic determinants of drug response--on the way to improve drug safety?
|
Herz
|
2003
|
0.76
|
|
100
|
Sildenafil response is influenced by the G protein beta 3 subunit GNB3 C825T polymorphism: a pilot study.
|
J Urol
|
2003
|
0.75
|
|
101
|
Association of GNB4 intron-1 haplotypes with survival in patients with UICC stage III and IV colorectal carcinoma.
|
Anticancer Res
|
2009
|
0.75
|
|
102
|
The -1364A/C Aquaporin 5 Gene Promoter Polymorphism Is Not Associated with Menière's Disease.
|
ISRN Otolaryngol
|
2012
|
0.75
|
|
103
|
GNAQ TT(-695/-694)GC Polymorphism Is Associated with Increased Gq Expression, Vascular Reactivity, and Myocardial Injury after Coronary Artery Bypass Surgery.
|
Anesthesiology
|
2017
|
0.75
|
|
104
|
Cloning and characterization of the GNA11 promoter and its regulation by early growth response 1.
|
Basic Clin Pharmacol Toxicol
|
2013
|
0.75
|
|
105
|
The CYP1A1 Ile462Val polymorphism and platinum resistance of epithelial ovarian neoplasms.
|
Oncol Res
|
2010
|
0.75
|
|
106
|
The GNB3 C825T polymorphism influences platelet aggregation in human whole blood.
|
Pharmacogenet Genomics
|
2012
|
0.75
|