Published in Biotechnol Genet Eng Rev on January 01, 2003
Conference report--gene therapy--quality matters. MedGenMed (2004) 0.75
Genome-wide association analysis identifies 13 new risk loci for schizophrenia. Nat Genet (2013) 7.44
Gene networks inference using dynamic Bayesian networks. Bioinformatics (2003) 2.74
Serotonin has a key role in pathogenesis of experimental colitis. Gastroenterology (2009) 2.55
Essential roles of enteric neuronal serotonin in gastrointestinal motility and the development/survival of enteric dopaminergic neurons. J Neurosci (2011) 2.21
Disruption of the nonneuronal tph1 gene demonstrates the importance of peripheral serotonin in cardiac function. Proc Natl Acad Sci U S A (2003) 2.19
Systems medicine and integrated care to combat chronic noncommunicable diseases. Genome Med (2011) 1.78
Maternal serotonin is crucial for murine embryonic development. Proc Natl Acad Sci U S A (2006) 1.75
Lentiviral vectors with a defective integrase allow efficient and sustained transgene expression in vitro and in vivo. Proc Natl Acad Sci U S A (2006) 1.74
No major schizophrenia locus detected on chromosome 1q in a large multicenter sample. Science (2002) 1.57
Smoking induces long-lasting effects through a monoamine-oxidase epigenetic regulation. PLoS One (2009) 1.53
Neurotoxic activation of microglia is promoted by a nox1-dependent NADPH oxidase. J Neurosci (2008) 1.34
PA700, the regulatory complex of the 26S proteasome, interferes with alpha-synuclein assembly. FEBS J (2005) 1.23
Perinatal undernutrition affects the methylation and expression of the leptin gene in adults: implication for the understanding of metabolic syndrome. FASEB J (2011) 1.23
TIMP-1 abolishes MMP-9-dependent long-lasting long-term potentiation in the prefrontal cortex. Biol Psychiatry (2007) 1.22
SOCS3-mediated blockade of JAK/STAT3 signaling pathway reveals its major contribution to spinal cord neuroinflammation and mechanical allodynia after peripheral nerve injury. J Neurosci (2010) 1.18
Silencing of OB-RGRP in mouse hypothalamic arcuate nucleus increases leptin receptor signaling and prevents diet-induced obesity. Proc Natl Acad Sci U S A (2007) 1.17
Human retinoic acid receptor-related orphan receptor alpha1 overexpression protects neurones against oxidative stress-induced apoptosis. J Neurochem (2006) 1.15
Non-integrating lentiviral vectors. Curr Gene Ther (2008) 1.13
Inducible cAMP early repressor, an endogenous antagonist of cAMP responsive element-binding protein, evokes neuronal apoptosis in vitro. J Neurosci (2003) 1.12
Grafts of brain-derived neurotrophic factor and neurotrophin 3-transduced primate Schwann cells lead to functional recovery of the demyelinated mouse spinal cord. J Neurosci (2005) 1.09
A single lentivirus vector mediates doxycycline-regulated expression of transgenes in the brain. Hum Gene Ther (2004) 1.08
Retinoid-related orphan receptor alpha controls the early steps of Purkinje cell dendritic differentiation. J Neurosci (2006) 1.06
Beta cells within single human islets originate from multiple progenitors. PLoS One (2008) 1.05
Recent advances in understanding serotonin regulation of cardiovascular function. Trends Mol Med (2004) 1.05
Genome-wide association study of multiplex schizophrenia pedigrees. Am J Psychiatry (2012) 1.05
Lentiviral-mediated targeted NF-kappaB blockade in dorsal spinal cord glia attenuates sciatic nerve injury-induced neuropathic pain in the rat. Mol Ther (2007) 1.04
Association between sodium- and potassium-activated adenosine triphosphatase alpha isoforms and bipolar disorders. Biol Psychiatry (2008) 1.01
Conditional NF-L transgene expression in mice for in vivo analysis of turnover and transport rate of neurofilaments. J Neurosci (2007) 1.01
Serotonin activates dendritic cell function in the context of gut inflammation. Am J Pathol (2011) 0.98
Ineffective erythropoiesis with reduced red blood cell survival in serotonin-deficient mice. Proc Natl Acad Sci U S A (2011) 0.98
BDNF-induced white matter neuroprotection and stage-dependent neuronal survival following a neonatal excitotoxic challenge. Cereb Cortex (2004) 0.96
Retinal cell type expression specificity of HIV-1-derived gene transfer vectors upon subretinal injection in the adult rat: influence of pseudotyping and promoter. J Gene Med (2005) 0.94
Lentiviral-mediated targeted transgene expression in dorsal spinal cord glia: tool for the study of glial cell implication in mechanisms underlying chronic pain development. J Neurosci Methods (2007) 0.92
Lentiviral vectors mediate nonimmunosuppressive rapamycin analog-induced production of secreted therapeutic factors in the brain: regulation at the level of transcription and exocytosis. Hum Gene Ther (2008) 0.92
SCLIP is crucial for the formation and development of the Purkinje cell dendritic arbor. J Neurosci (2008) 0.91
Defective axonal transport of neurofilament proteins in neurons overexpressing peripherin. J Neurochem (2006) 0.88
Grafted human embryonic progenitors expressing neurogenin-2 stimulate axonal sprouting and improve motor recovery after severe spinal cord injury. PLoS One (2010) 0.88
A new strategy to generate functional insulin-producing cell lines by somatic gene transfer into pancreatic progenitors. PLoS One (2009) 0.88
Zinc finger protein 191 (ZNF191/Zfp191) is necessary to maintain neural cells as cycling progenitors. Stem Cells (2009) 0.88
Control of small inhibitory RNA levels and RNA interference by doxycycline induced activation of a minimal RNA polymerase III promoter. Nucleic Acids Res (2006) 0.87
A novel and efficient gene transfer strategy reduces glial reactivity and improves neuronal survival and axonal growth in vitro. PLoS One (2009) 0.87
Maternal serotonin influences cardiac function in adult offspring. FASEB J (2008) 0.86
Expression of the transcription factor Zfp191 during embryonic development in the mouse. Gene Expr Patterns (2007) 0.86
Targeting conditional gene modification into the serotonin neurons of the dorsal raphe nucleus by viral delivery of the Cre recombinase. Mol Cell Neurosci (2003) 0.86
Efficient myelin repair in the macaque spinal cord by autologous grafts of Schwann cells. Brain (2005) 0.86
Optimization of transgene expression at the posttranscriptional level in neural cells: implications for gene therapy. Mol Ther (2003) 0.86
Differential amplification of intron-containing transcripts reveals long term potentiation-associated up-regulation of specific Pde10A phosphodiesterase splice variants. J Biol Chem (2004) 0.85
Silencing of choline acetyltransferase expression by lentivirus-mediated RNA interference in cultured cells and in the adult rodent brain. J Neurosci Res (2009) 0.85
Cell death and neuronal differentiation of glioblastoma stem-like cells induced by neurogenic transcription factors. Glia (2012) 0.85
The tissue-specific methylation of the human tyrosine hydroxylase gene reveals new regulatory elements in the first exon. J Neurochem (2005) 0.85
1-methyl-4-phenylpyridinium neurotoxicity is attenuated by adenoviral gene transfer of human Cu/Zn superoxide dismutase. J Neurosci Res (2006) 0.84
Abnormal TDP-43 and FUS proteins in muscles of sporadic IBM: similarities in a TARDBP-linked ALS patient. J Neurol Neurosurg Psychiatry (2010) 0.84
ZENON, a novel POZ Kruppel-like DNA binding protein associated with differentiation and/or survival of late postmitotic neurons. Mol Cell Biol (2005) 0.84
Long-term expression of beta-glucuronidase by genetically modified human neural progenitor cells grafted into the mouse central nervous system. Mol Cell Neurosci (2002) 0.83
Expression of PRiMA in the mouse brain: membrane anchoring and accumulation of 'tailed' acetylcholinesterase. Eur J Neurosci (2003) 0.83
Lentiviral-mediated gene transfer of brain-derived neurotrophic factor is neuroprotective in a mouse model of neonatal excitotoxic challenge. J Neurosci Res (2006) 0.83
Differential expression and regulation of the high-affinity choline transporter CHT1 and choline acetyltransferase in neurons of superior cervical ganglia. Mol Cell Neurosci (2005) 0.82
Tet system in the brain: transgenic rats and lentiviral vectors approach. Genesis (2009) 0.81
Neonatal handling prevents the effects of phencyclidine in an animal model of negative symptoms of schizophrenia. Biol Psychiatry (2006) 0.81
More than one way to toy with ChAT and VAChT. J Physiol Paris (2001) 0.81
Transforming growth factor beta1 overexpression in the nigrostriatal system increases the dopaminergic deficit of MPTP mice. Mol Cell Neurosci (2003) 0.79
Neuronal transfer of the human Cu/Zn superoxide dismutase gene increases the resistance of dopaminergic neurons to 6-hydroxydopamine. J Neurochem (2002) 0.79
Mammalian prenatal development: the influence of maternally derived molecules. Bioessays (2009) 0.79
Overexpression of basic helix-loop-helix transcription factors enhances neuronal differentiation of fetal human neural progenitor cells in various ways. Stem Cells Dev (2011) 0.79
Functional reinnervation from remaining DA terminals induced by GDNF lentivirus in a rat model of early Parkinson's disease. Neurobiol Dis (2005) 0.79
Rapid cohort generation and analysis of disease spectrum of large animal model of cone dystrophy. PLoS One (2013) 0.79
Molecular Cloning of Forebrain mRNAs which are Modulated by Sleep Deprivation. Eur J Neurosci (1990) 0.78
Neurotensin induces tyrosine hydroxylase gene activation through nitric oxide and protein kinase C signaling pathways. Mol Pharmacol (2002) 0.78
Mass spectrometry reveals changes in MHC I antigen presentation after lentivector expression of a gene regulation system. Mol Ther Nucleic Acids (2013) 0.78
Behavioural Effect of Engineered Cells that Synthesize l-dopa or Dopamine after Grafting into the Rat Neostriatum. Eur J Neurosci (1990) 0.78
Gi/Go protein-dependent presynaptic mechanisms are involved in clozapine-induced down-regulation of tyrosine hydroxylase in PC12 cells. J Neurosci Res (2005) 0.78
Tyrosine hydroxylase mRNA and protein are down-regulated by chronic clozapine in both the mesocorticolimbic and the nigrostriatal systems. J Neurosci Res (2003) 0.77
Obsessive compulsive disorder--prevalence in Xhosa-speaking schizophrenia patients. S Afr Med J (2005) 0.77
Adenoviral retrograde gene transfer in motoneurons is greatly enhanced by prior intramuscular inoculation with botulinum toxin. Hum Gene Ther (2002) 0.77
Lentiviral-mediated silencing of glial fibrillary acidic protein and vimentin promotes anatomical plasticity and functional recovery after spinal cord injury. J Neurosci Res (2014) 0.77
Genome-scan for bipolar disorder with sib-pair families in the Sardinian population: a new susceptibility locus on chromosome 1p22-p21? Am J Med Genet B Neuropsychiatr Genet (2010) 0.77
Post-genomic era and gene discovery for psychiatric diseases: there is a new art of the trade? The example of the HUMTH01 microsatellite in the Tyrosine Hydroxylase gene. Mol Neurobiol (2002) 0.77
The extract of Ginkgo biloba EGb 761 reactivates a juvenile profile in the skeletal muscle of sarcopenic rats by transcriptional reprogramming. PLoS One (2009) 0.77
Paradoxical methylation of the tyrosine hydroxylase gene in mouse preimplantation embryos. Genomics (2002) 0.77
Integration of genetically modified adult astrocytes into the lesioned rat spinal cord. J Neurosci Res (2006) 0.77
Long-term fate of human telencephalic progenitor cells grafted into the adult mouse brain: effects of previous amplification in vitro. J Neurosci Res (2002) 0.76
Quantification of transcriptional activities of reporter gene constructs in primary cultures of sympathetic neurons. J Neurosci Res (2003) 0.76
Role of Dopaminergic D2 Receptors in the Regulation of Glutamic Acid Decarboxylase Messenger RNA in the Striatum of the Rat. Eur J Neurosci (1992) 0.76
Manic-depressive illness: an association study with the inositol polyphosphate 1-phosphatase and serotonin transporter genes. Psychiatr Genet (2002) 0.75
CAG repeat polymorphisms in KCNN3 (HSKCa3) and PPP2R2B show no association or linkage to schizophrenia. Am J Med Genet B Neuropsychiatr Genet (2003) 0.75
Positive and negative symptoms in affected sib pairs with schizophrenia: implications for genetic studies in an African Xhosa sample. Schizophr Res (2005) 0.75
cDNA libraries from a low amount of cells. Methods Mol Biol (2003) 0.75
Transplantation of human adult astrocytes: efficiency and safety requirements for an autologous gene therapy. J Neurosci Res (2003) 0.75
The Budapest Meeting 2005 intensified networking on ethics of science: the case of reproductive cloning, germline gene therapy and human dignity. Sci Eng Ethics (2006) 0.75
[Abnormal cardiac activity in mice in the absence of peripheral serotonin synthesis]. J Soc Biol (2004) 0.75