Major malformations in infants exposed to antiepileptic drugs in utero, with emphasis on carbamazepine and valproic acid: a nation-wide, population-based register study.

PubWeight™: 2.34‹?› | Rank: Top 2%

🔗 View Article (PMID 15046269)

Published in Acta Paediatr on February 01, 2004

Authors

K Wide1, B Winbladh, B Källén

Author Affiliations

1: Department of Clinical Sciences, Division of Pediatrics, Karolinska Insitutet, Huddinge University Hospital, Stockholm, Sweden. katarina.wide@klinvet.ki.se

Associated clinical trials:

Effects and Consequences for Mother and Child From Treatment for Depression (MAGDALENA) | NCT02185547

Articles citing this

Cognitive function at 3 years of age after fetal exposure to antiepileptic drugs. N Engl J Med (2009) 6.66

Malformation risks of antiepileptic drugs in pregnancy: a prospective study from the UK Epilepsy and Pregnancy Register. J Neurol Neurosurg Psychiatry (2005) 4.86

In utero antiepileptic drug exposure: fetal death and malformations. Neurology (2006) 3.64

Intrauterine exposure to carbamazepine and specific congenital malformations: systematic review and case-control study. BMJ (2010) 2.77

Practice parameter update: management issues for women with epilepsy--focus on pregnancy (an evidence-based review): teratogenesis and perinatal outcomes: report of the Quality Standards Subcommittee and Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology and American Epilepsy Society. Neurology (2009) 2.58

Pregnancy outcomes in women with epilepsy: a systematic review and meta-analysis of published pregnancy registries and cohorts. Epilepsy Res (2008) 2.02

Antiepileptic drug use by pregnant women enrolled in Florida Medicaid. Neurology (2015) 1.41

Pregnancy with epilepsy: obstetric and neonatal outcome of a controlled study. Seizure (2009) 1.28

Teratogenicity of antiepileptic medications. Semin Neurol (2008) 1.16

Use of antiepileptic medications in pregnancy in relation to risks of birth defects. Ann Epidemiol (2011) 1.08

Teratogenic effects of antiepileptic drugs. Expert Rev Neurother (2010) 1.05

Antiepileptic drugs during pregnancy: what is known and which AEDs seem to be safest? Epilepsia (2008) 1.04

Antiepileptic drug use in women of childbearing age. Epilepsy Behav (2009) 0.99

Epilepsy in pregnancy. BMJ (2007) 0.97

Using current evidence in selecting antiepileptic drugs for use during pregnancy. Epilepsy Curr (2005) 0.95

Mouse models of autism: testing hypotheses about molecular mechanisms. Curr Top Behav Neurosci (2011) 0.93

Preconception care: screening and management of chronic disease and promoting psychological health. Reprod Health (2014) 0.92

Antiepileptic drugs and pregnancy outcomes. Am J Med Genet A (2012) 0.92

The use of central nervous system active drugs during pregnancy. Pharmaceuticals (Basel) (2013) 0.92

Burnei-Gavriliu classification of congenital scoliosis. J Med Life (2015) 0.85

Major malformations with valproic acid. Can Fam Physician (2006) 0.83

Effects of in utero antiepileptic drug exposure. Epilepsy Curr (2009) 0.81

Pregnancy and epilepsy: what should we tell our patients? J Neurol (2009) 0.79

Teratogenicity of lamotrigine. Can Fam Physician (2007) 0.79

Alteration of bioelectrically-controlled processes in the embryo: a teratogenic mechanism for anticonvulsants. Reprod Toxicol (2014) 0.78

Placenta transfer and toxicokinetics of valproic Acid in pregnant cynomolgus monkeys. Toxicol Res (2010) 0.78

Effect of anti-epileptic drugs in pregnancy and teratogenesis. Indian J Clin Biochem (2008) 0.77

NICE guidance on newer drugs for epilepsy in adults. BMJ (2004) 0.77

Behavioral outcomes in children exposed prenatally to lamotrigine, valproate, or carbamazepine. Neurotoxicol Teratol (2016) 0.76

Teratogenicity of Antiepileptic Drugs. Clin Psychopharmacol Neurosci (2017) 0.75

Treatment of bipolar disorders during pregnancy: maternal and fetal safety and challenges. Drug Healthc Patient Saf (2014) 0.75

Long-term consequences after exposure to antiepileptic drugs in utero. Ther Adv Drug Saf (2011) 0.75

Optimizing prophylactic treatment of migraine: Subtypes and patient matching. Ther Clin Risk Manag (2008) 0.75

When should we pay attention to unfavorable news from pregnancy registries? Epilepsy Curr (2007) 0.75

Women and epilepsy. J Pediatr Pharmacol Ther (2009) 0.75

The Risk of Specific Congenital Anomalies in Relation to Newer Antiepileptic Drugs: A Literature Review. Drugs Real World Outcomes (2016) 0.75

Milk transfer and toxicokinetics of valproic Acid in lactating cynomolgus monkeys. Toxicol Res (2013) 0.75

[Congenital malformations of the growing spine : When should treatment be conservative and when should it be surgical?]. Orthopade (2016) 0.75

Unilateral multicystic dysplastic kidney in infants exposed to antiepileptic drugs during pregnancy. Pediatr Nephrol (2007) 0.75

Articles by these authors

A quality study of a medical birth registry. Scand J Soc Med (1990) 4.96

Delivery outcome after maternal use of antidepressant drugs in pregnancy: an update using Swedish data. Psychol Med (2010) 2.55

Administration of vitamin K to newborn infants and childhood cancer. BMJ (1993) 2.52

VATER non-random association of congenital malformations: study based on data from four malformation registers. Am J Med Genet (2001) 2.34

The Stockholm birth centre trial: maternal and infant outcome. Br J Obstet Gynaecol (1997) 2.28

Delivery outcome after the use of antidepressants in early pregnancy. Eur J Clin Pharmacol (1999) 1.85

Congenital malformations among infants whose mothers had gestational diabetes or preexisting diabetes. Early Hum Dev (2001) 1.82

Congenital malformations in infants born after IVF: a population-based study. Hum Reprod (2001) 1.76

Reproductive outcome after anesthesia and operation during pregnancy: a registry study of 5405 cases. Am J Obstet Gynecol (1989) 1.76

Coeliac disease is associated with intrauterine growth and neonatal infections. Acta Paediatr (2002) 1.72

A Swedish register of congenital malformations. Experience with continuous registration during 2 years with special reference to multiple malformations. Pediatrics (1968) 1.63

CHARGE Association in newborns: a registry-based study. Teratology (1999) 1.55

Surveillance of smoking during pregnancy in Sweden, 1983-1987. Acta Obstet Gynecol Scand (1991) 1.44

Hospitalization for vascular complications in childhood onset type 1 diabetes--effects of gender and age at onset. Acta Paediatr (2008) 1.44

A joint international study on the epidemiology of hypospadias. Acta Paediatr Scand Suppl (1986) 1.43

Appendectomy during pregnancy: a Swedish registry study of 778 cases. Obstet Gynecol (1991) 1.42

Early discharge of preterm infants followed by domiciliary nursing care: parents' anxiety, assessment of infant health and breastfeeding. Acta Paediatr (2001) 1.42

Maternal-child blood group incompatibility and other perinatal events increase the risk for early-onset type 1 (insulin-dependent) diabetes mellitus. Diabetologia (1992) 1.39

Incidence of congenital malformations in children born after ICSI. Hum Reprod (2000) 1.36

Surveillance of malformations at birth: a comparison of two record systems run in parallel. Int J Epidemiol (1977) 1.30

Pregnancy outcome for women working in laboratories in some of the pharmaceutical industries in Sweden. Scand J Work Environ Health (1980) 1.27

Very low birthweight boys at the age of 19. Arch Dis Child Fetal Neonatal Ed (1998) 1.27

Cigarette smoking as an etiologic factor in cleft lip and palate. Am J Obstet Gynecol (1979) 1.24

Laparoscopy during pregnancy: a study of five fetal outcome parameters with use of the Swedish Health Registry. Am J Obstet Gynecol (1997) 1.22

Hospital care utilization of infants born after IVF. Hum Reprod (2002) 1.21

Caudal mesoderm pattern of anomalies: from renal agenesis to sirenomelia. Teratology (1974) 1.20

Impaired mixed leucocyte reaction in some different diseases, notably multiple sclerosis and various arthritides. Clin Exp Immunol (1971) 1.20

An epidemiological study of hypospadias in Sweden. Acta Paediatr Scand Suppl (1982) 1.16

Dealing with suspicions of malformation frequency increase. Experience with the Swedish register of congenital malformations. Acta Paediatr Scand Suppl (1979) 1.15

An epidemiological study of work with video screens and pregnancy outcome: II. A case-control study. Am J Ind Med (1986) 1.15

Pregnancy and delivery characteristics of women whose infants develop child cancer. A study based on registry information. APMIS (1990) 1.12

Psychomotor development in preschool children exposed to antiepileptic drugs in utero. Acta Paediatr (2002) 1.12

The epidemiology of orofacial clefts. 1. Some general epidemiological characteristics. J Craniofac Genet Dev Biol (1997) 1.11

Lithium and pregnancy. A cohort study on manic-depressive women. Acta Psychiatr Scand (1983) 1.10

The epidemiology of anotia and microtia. J Med Genet (1996) 1.09

The influence of amphetamine addiction on pregnancy and the newborn infant. Acta Paediatr Scand (1978) 1.07

Socio-economic variables and pregnancy outcome. Birthweight in singletons. Acta Paediatr Scand Suppl (1989) 1.07

Search for teratogenic risks with the aid of malformation registries. Teratology (1987) 1.06

Pilot study of nebulized surfactant therapy for neonatal respiratory distress syndrome. Acta Paediatr (2000) 1.05

Socio-economic variables and pregnancy outcome. 2. Infant and child survival. Acta Paediatr Scand (1990) 1.05

Infants with congenital limb reduction registered in the Swedish Register of Congenital Malformations. Teratology (1984) 1.05

Survey of infants born in 1973 or 1975 to Swedish women working in operating rooms during their pregnancies. Anesth Analg (1979) 1.03

Time trends of spina bifida in Sweden 1947-81. J Epidemiol Community Health (1984) 1.03

Gastrointestinal atresia and maternal occupation during pregnancy. J Occup Med (1982) 1.03

Intrauterine growth pattern and risk of childhood onset insulin dependent (type I) diabetes: population based case-control study. BMJ (1996) 1.02

Delivery outcome for women working in the pulp and paper industry. Scand J Work Environ Health (1981) 1.01

A prospective study of drugs and pregnancy. II. Anti-emetic drugs. Acta Obstet Gynecol Scand (1976) 1.01

A registry study of very low birthweight liveborn infants in Sweden, 1973-1988. Acta Obstet Gynecol Scand (1992) 1.01

Descriptive epidemiology of alimentary tract atresia. Teratology (1995) 1.00

Congenital malformations in twins: a population study. Acta Genet Med Gemellol (Roma) (1986) 0.98

Epidemiology of choanal atresia with special reference to the CHARGE association. Pediatrics (1997) 0.98

Outcome of pregnancy after clomiphene therapy. Acta Obstet Gynecol Scand (1976) 0.98

A prospective study of drugs and pregnancy. 4. Miscellaneous drugs. Acta Obstet Gynecol Scand (1976) 0.97

Monitoring of congenital cardiac defects. Pediatr Cardiol (1987) 0.96

Epidemiologic characteristics of kidney malformations. Eur J Epidemiol (2000) 0.95

School marks for Swedish children whose mothers had diabetes during pregnancy: a population-based study. Diabetologia (2007) 0.95

Absence of limbs and gross body wall defects: an epidemiological study of related rare malformation conditions. Teratology (1992) 0.94

Maternal occupation and delivery outcome: a study using central registry data. Acta Paediatr Scand (1987) 0.93

School performance in children with type 1 diabetes--a population-based register study. Diabetologia (2007) 0.92

Use of multivitamins and folic acid in early pregnancy and multiple births in Sweden. Twin Res (2001) 0.92

Effects of cerebrospinal fluid on cultured blood leukocytes from patients with multiple sclerosis. Acta Neurol Scand (1971) 0.92

Psychomotor development and minor anomalies in children exposed to antiepileptic drugs in utero: a prospective population-based study. Dev Med Child Neurol (2000) 0.91

The epidemiology of diaphragmatic hernia. Eur J Epidemiol (1997) 0.91

Major malformations in infants born of women who worked in laboratories while pregnant. Lancet (1979) 0.90

Pregnancy outcome in women working as dentists, dental assistants or dental technicians. Int Arch Occup Environ Health (1989) 0.90

Early discharge of preterm infants needing limited special care, followed by domiciliary nursing care. Acta Paediatr (1999) 0.90

Delivery outcome after infertility--a registry study. Fertil Steril (1991) 0.89

OEIS complex--a population study. Am J Med Genet (2000) 0.88

Eosinophil activation in preterm infants with lung disease. Acta Paediatr (2007) 0.88

Effect of encephalitogenic protein on migration in agarose of leukocytes from patients with multiple sclerosis. A longitudinal study of patients with relapsing multiple sclerosis or with cerebral infarction. Acta Neurol Scand (1977) 0.87

Conjoined twinning in Sweden. Acta Obstet Gynecol Scand (1978) 0.87

Environmental factors in the etiology of neural tube defects: a negative study. Environ Res (1988) 0.87

Secular trends in the effect of socio-economic factors on birth weight and infant survival in Sweden. Scand J Soc Med (1993) 0.86

Blood cell galactose-1-phosphate uridyl transferase activity in dysplastic patients, with and without chromosomal aberrations. Hum Hered (1969) 0.85

A prospective study of drugs and pregnancy. I. Psychopharmaca. Acta Obstet Gynecol Scand (1976) 0.85

An epidemiological study of work with video screens and pregnancy outcome: I. A registry study. Am J Ind Med (1986) 0.85

The effects of pharmacological treatment on pulmonary function in children with exercise-induced asthma. Acta Paediatr Scand (1980) 0.85

Effect of maternal age distribution and prenatal diagnosis on the population rates of Down syndrome--a comparative study of nineteen populations. Hereditas (1989) 0.84

Congenital malformations in the southeast of Sweden--a registry study with validation. Acta Paediatr (2000) 0.84

Effect of basic encephalitogenic protein and some peptides derived from it on the migration in agarose gel of leukocytes from patients with multiple sclerosis, other neurological diseases, or carcinoma. Acta Neurol Scand (1974) 0.84

Delivery outcome in women employed in medical occupations in Sweden. J Occup Med (1979) 0.83

Cerebrospinal fluid clearance of choline and some other amines. Acta Physiol Scand (1972) 0.83

Multiple malformations studied with a national register of malformations. Pediatrics (1969) 0.83

Fetal growth and congenital malformations. Ultrasound Obstet Gynecol (2007) 0.83

Delivery outcome of women working in laboratories during pregnancy. Arch Environ Health (1984) 0.83

Body dimensions of infants exposed to antiepileptic drugs in utero: observations spanning 25 years. Epilepsia (2000) 0.83

A prospective study of drugs and pregnancy. 3. Hormones. Acta Obstet Gynecol Scand (1976) 0.82

Is there an association of Down Syndrome and omphalocele? Am J Med Genet (1999) 0.82

Childhood malignancy and maternal diabetes or other auto-immune disease during pregnancy. Br J Cancer (2002) 0.82

Errors in differentiation of the central nervous system. Birth Defects Orig Artic Ser (1979) 0.82

Early neonatal events and the disease incidence in nonobese diabetic mice. Pediatr Res (1997) 0.82

Major and minor malformations in newborns and infants up to one year of age. Acta Paediatr Scand (1970) 0.81

Studies of experimental allergic encephalomyelitis and multiple sclerosis with aid of glia cell culture. Acta Neurol Scand Suppl (1965) 0.81

Maternal risk factors for cause-specific stillbirth and neonatal death. Acta Obstet Gynecol Scand (2001) 0.81

Mixed leukocyte reaction and hl-a specificity at multiple sclerosis. Acta Neurol Scand (1975) 0.81

Birth weight, body length, and cranial circumference in newborns with cleft lip or palate. Cleft Palate Craniofac J (1998) 0.81

Pregnancy outcome in Sweden after the Chernobyl accident. Environ Res (1994) 0.80

Effect of 2-mercaptoethanol on the mixed leukocyte reaction in man. Probable effect on blastogenic factor stabilization. Acta Pathol Microbiol Scand C (1976) 0.80

Discordant twin growth in utero and differences in blood pressure and endothelial function at 8 years of age. J Intern Med (2006) 0.80