Published in Genesis on April 01, 2004
Smaller inner ear sensory epithelia in Neurog 1 null mice are related to earlier hair cell cycle exit. Dev Dyn (2005) 2.71
Notch2, but not Notch1, is required for proximal fate acquisition in the mammalian nephron. Development (2007) 2.70
Loss of inhibitory interneurons in the dorsal spinal cord and elevated itch in Bhlhb5 mutant mice. Neuron (2010) 2.69
Hey2 regulation by FGF provides a Notch-independent mechanism for maintaining pillar cell fate in the organ of Corti. Dev Cell (2009) 2.11
TMIE is an essential component of the mechanotransduction machinery of cochlear hair cells. Neuron (2014) 1.87
Reconstruction of the mouse otocyst and early neuroblast lineage at single-cell resolution. Cell (2014) 1.82
Developmental origin of vaginal epithelium. Differentiation (2010) 1.70
Residual microRNA expression dictates the extent of inner ear development in conditional Dicer knockout mice. Dev Biol (2009) 1.55
Shaping sound in space: the regulation of inner ear patterning. Development (2012) 1.48
Fast synaptic inhibition in spinal sensory processing and pain control. Physiol Rev (2012) 1.45
Spontaneous Activity of Cochlear Hair Cells Triggered by Fluid Secretion Mechanism in Adjacent Support Cells. Cell (2015) 1.44
Notch signaling augments the canonical Wnt pathway to specify the size of the otic placode. Development (2008) 1.42
A differential developmental pattern of spinal interneuron apoptosis during synaptogenesis: insights from genetic analyses of the protocadherin-gamma gene cluster. Development (2008) 1.41
Lgl1 Is Required for Olfaction and Development of Olfactory Bulb in Mice. PLoS One (2016) 1.41
Targeted connexin26 ablation arrests postnatal development of the organ of Corti. Biochem Biophys Res Commun (2009) 1.32
Neurod1 suppresses hair cell differentiation in ear ganglia and regulates hair cell subtype development in the cochlea. PLoS One (2010) 1.30
The small GTPase Rac1 regulates auditory hair cell morphogenesis. J Neurosci (2009) 1.24
Conditional deletion of Atoh1 using Pax2-Cre results in viable mice without differentiated cochlear hair cells that have lost most of the organ of Corti. Hear Res (2010) 1.22
BMP signaling is necessary for patterning the sensory and nonsensory regions of the developing mammalian cochlea. J Neurosci (2010) 1.22
Mutant mice reveal the molecular and cellular basis for specific sensory connections to inner ear epithelia and primary nuclei of the brain. Hear Res (2005) 1.15
A molecular analysis of neurogenic placode and cranial sensory ganglion development in the shark, Scyliorhinus canicula. Dev Biol (2006) 1.14
Tissue-specific roles of Tbx1 in the development of the outer, middle and inner ear, defective in 22q11DS patients. Hum Mol Genet (2006) 1.13
SOX9 controls epithelial branching by activating RET effector genes during kidney development. Hum Mol Genet (2011) 1.13
Neurod1 regulates survival and formation of connections in mouse ear and brain. Cell Tissue Res (2010) 1.12
Pax2 and Pax8 cooperate in mouse inner ear morphogenesis and innervation. BMC Dev Biol (2010) 1.12
Near-infrared laser illumination transforms the fluorescence absorbing X-Gal reaction product BCI into a transparent, yet brightly fluorescent substance. Brain Res Bull (2005) 1.10
Canonical Notch signaling is not necessary for prosensory induction in the mouse cochlea: insights from a conditional mutant of RBPjkappa. J Neurosci (2011) 1.09
Canal cristae growth and fiber extension to the outer hair cells of the mouse ear require Prox1 activity. PLoS One (2010) 1.08
Dual embryonic origin of the mammalian otic vesicle forming the inner ear. Development (2011) 1.07
Cell degeneration is not a primary causer for Connexin26 (GJB2) deficiency associated hearing loss. Neurosci Lett (2012) 1.00
Dystroglycan does not contribute significantly to kidney development or function, in health or after injury. Am J Physiol Renal Physiol (2011) 1.00
Molecular and tissue interactions governing induction of cranial ectodermal placodes. Dev Biol (2009) 1.00
Continued expression of GATA3 is necessary for cochlear neurosensory development. PLoS One (2013) 0.99
Direct and Indirect Regulation of Spinal Cord Ia Afferent Terminal Formation by the γ-Protocadherins. Front Mol Neurosci (2011) 0.99
Tympanic border cells are Wnt-responsive and can act as progenitors for postnatal mouse cochlear cells. Development (2013) 0.99
Conditional deletion of N-Myc disrupts neurosensory and non-sensory development of the ear. Dev Dyn (2011) 0.98
Defects in the cerebella of conditional Neurod1 null mice correlate with effective Tg(Atoh1-cre) recombination and granule cell requirements for Neurod1 for differentiation. Cell Tissue Res (2009) 0.97
Postnatal refinement of auditory hair cell planar polarity deficits occurs in the absence of Vangl2. J Neurosci (2013) 0.97
Long-distance three-color neuronal tracing in fixed tissue using NeuroVue dyes. Immunol Invest (2007) 0.96
Developmental expression of Kcnq4 in vestibular neurons and neurosensory epithelia. Brain Res (2007) 0.95
Minor change, major difference: divergent functions of highly conserved cis-regulatory elements subsequent to whole genome duplication events. Development (2011) 0.94
Little but loud: small RNAs have a resounding affect on ear development. Brain Res (2009) 0.94
Hoxa1 lineage tracing indicates a direct role for Hoxa1 in the development of the inner ear, the heart, and the third rhombomere. Dev Biol (2010) 0.93
PTK7-Src signaling at epithelial cell contacts mediates spatial organization of actomyosin and planar cell polarity. Dev Cell (2014) 0.93
MicroRNAs and epigenetic regulation in the mammalian inner ear: implications for deafness. Mamm Genome (2009) 0.93
The role of sensory organs and the forebrain for the development of the craniofacial shape as revealed by Foxg1-cre-mediated microRNA loss. Genesis (2011) 0.92
Canonical Wnt signaling modulates Tbx1, Eya1, and Six1 expression, restricting neurogenesis in the otic vesicle. Dev Dyn (2010) 0.90
Sprouty1 and Sprouty2 limit both the size of the otic placode and hindbrain Wnt8a by antagonizing FGF signaling. Dev Biol (2011) 0.89
Graded levels of Pax2a and Pax8 regulate cell differentiation during sensory placode formation. Development (2012) 0.89
Inner ear hair cells deteriorate in mice engineered to have no or diminished innervation. Front Aging Neurosci (2015) 0.89
MicroRNAs in mouse development and disease. Semin Cell Dev Biol (2010) 0.89
Conditional gene expression in the mouse inner ear using Cre-loxP. J Assoc Res Otolaryngol (2012) 0.89
Non-coding RNAs in the development of sensory organs and related diseases. Cell Mol Life Sci (2013) 0.88
Role of mitofusin 2 in the renal stress response. PLoS One (2012) 0.87
Identification of novel Hoxa1 downstream targets regulating hindbrain, neural crest and inner ear development. Dev Biol (2011) 0.87
Vertebrate Lrig3-ErbB interactions occur in vitro but are unlikely to play a role in Lrig3-dependent inner ear morphogenesis. PLoS One (2010) 0.86
GATA3 controls the specification of prosensory domain and neuronal survival in the mouse cochlea. Hum Mol Genet (2013) 0.86
Hey1 and Hey2 control the spatial and temporal pattern of mammalian auditory hair cell differentiation downstream of Hedgehog signaling. J Neurosci (2014) 0.86
Fgf16(IRESCre) mice: a tool to inactivate genes expressed in inner ear cristae and spiral prominence epithelium. Dev Dyn (2009) 0.85
PTEN regulation of the proliferation and differentiation of auditory progenitors through the PTEN/PI3K/Akt-signaling pathway in mice. Neuroreport (2014) 0.85
Analysis of FGF-dependent and FGF-independent pathways in otic placode induction. PLoS One (2013) 0.85
Conditional and inducible gene recombineering in the mouse inner ear. Brain Res (2006) 0.84
BMP signaling controls formation of a primordial germ cell niche within the early genital ridges. Dev Biol (2010) 0.84
The myc road to hearing restoration. Cells (2012) 0.83
A transcription factor code defines nine sensory interneuron subtypes in the mechanosensory area of the spinal cord. PLoS One (2013) 0.82
Congenital aural atresia associated with agenesis of internal carotid artery in a girl with a FOXI3 deletion. Am J Med Genet A (2015) 0.82
Mutational ataxia resulting from abnormal vestibular acquisition and processing is partially compensated for. Behav Neurosci (2012) 0.81
Conditional deletion of the human ortholog gene Dicer1 in Pax2-Cre expression domain impairs orofacial development. Indian J Hum Genet (2012) 0.81
Diethylstilbestrol induces vaginal adenosis by disrupting SMAD/RUNX1-mediated cell fate decision in the Müllerian duct epithelium. Dev Biol (2013) 0.80
Correct timing of proliferation and differentiation is necessary for normal inner ear development and auditory hair cell viability. Dev Dyn (2013) 0.80
Conserved role of Sonic Hedgehog in tonotopic organization of the avian basilar papilla and mammalian cochlea. Proc Natl Acad Sci U S A (2015) 0.80
Mechanosensory hair cells express two molecularly distinct mechanotransduction channels. Nat Neurosci (2016) 0.79
Ultrastructural pathological changes in the cochlear cells of connexin 26 conditional knockout mice. Mol Med Rep (2013) 0.79
Redundant functions of Rac GTPases in inner ear morphogenesis. Dev Biol (2011) 0.79
The role of foxi family transcription factors in the development of the ear and jaw. Curr Top Dev Biol (2015) 0.79
Pkd1 is required for male reproductive tract development. Mech Dev (2013) 0.79
A causative link between inner ear defects and long-term striatal dysfunction. Science (2013) 0.78
DLG1 influences distal ureter maturation via a non-epithelial cell autonomous mechanism involving reduced retinoic acid signaling, Ret expression, and apoptosis. Dev Biol (2014) 0.78
SoxC transcription factors are essential for the development of the inner ear. Proc Natl Acad Sci U S A (2015) 0.78
L-type CaV1.2 deletion in the cochlea but not in the brainstem reduces noise vulnerability: implication for CaV1.2-mediated control of cochlear BDNF expression. Front Mol Neurosci (2013) 0.78
Fine-tuning of Notch signaling sets the boundary of the organ of Corti and establishes sensory cell fates. Elife (2016) 0.78
Transgenic mice and their impact on kidney research. Pflugers Arch (2008) 0.77
Sox9 is critical for suppression of neurogenesis but not initiation of gliogenesis in the cerebellum. Mol Brain (2015) 0.77
The RNA-binding protein LIN28B regulates developmental timing in the mammalian cochlea. Proc Natl Acad Sci U S A (2015) 0.77
The mouse Foxi3 transcription factor is necessary for the development of posterior placodes. Dev Biol (2015) 0.76
Conditional and constitutive expression of a Tbx1-GFP fusion protein in mice. BMC Dev Biol (2013) 0.76
Canonical Notch signaling plays an instructive role in auditory supporting cell development. Sci Rep (2016) 0.76
Spiral Ganglion Neuron Projection Development to the Hindbrain in Mice Lacking Peripheral and/or Central Target Differentiation. Front Neural Circuits (2017) 0.75
Fgf3 and Fgf10a work in concert to promote maturation of the epibranchial placodes in zebrafish. PLoS One (2013) 0.75
BDNF in Lower Brain Parts Modifies Auditory Fiber Activity to Gain Fidelity but Increases the Risk for Generation of Central Noise After Injury. Mol Neurobiol (2015) 0.75
Hepatocyte Growth Factor-c-MET Signaling Mediates the Development of Nonsensory Structures of the Mammalian Cochlea and Hearing. J Neurosci (2016) 0.75
Novel roles of Pkd2 in male reproductive system development. Differentiation (2014) 0.75
Indispensable role of Mdm2/p53 interaction during the embryonic and postnatal inner ear development. Sci Rep (2017) 0.75
Celsr1 coordinates the planar polarity of vestibular hair cells during inner ear development. Dev Biol (2017) 0.75
Analysis of Kif5b expression during mouse kidney development. PLoS One (2015) 0.75
Loss of Zeb2 in mesenchyme-derived nephrons causes primary glomerulocystic disease. Kidney Int (2016) 0.75
Single-Cell Transcriptome Analysis of Developing and Regenerating Spiral Ganglion Neurons. Curr Pharmacol Rep (2016) 0.75
Astrocytes follow ganglion cell axons to establish an angiogenic template during retinal development. Glia (2017) 0.75
The severity of vestibular dysfunction in deafness as a determinant of comorbid hyperactivity or anxiety. J Neurosci (2017) 0.75
Conditional knockout of Foxc2 gene in kidney: efficient generation of conditional alleles of single-exon gene by double-selection system. Mamm Genome (2015) 0.75
Mammalian cochlear supporting cells can divide and trans-differentiate into hair cells. Nature (2006) 2.65
Hey2 regulation by FGF provides a Notch-independent mechanism for maintaining pillar cell fate in the organ of Corti. Dev Cell (2009) 2.11
Wnt signals mediate a fate decision between otic placode and epidermis. Development (2006) 1.94
Cross-regulation of Ngn1 and Math1 coordinates the production of neurons and sensory hair cells during inner ear development. Development (2007) 1.76
Notch signaling augments the canonical Wnt pathway to specify the size of the otic placode. Development (2008) 1.42
The first steps towards hearing: mechanisms of otic placode induction. Int J Dev Biol (2007) 1.34
Competence of cranial ectoderm to respond to Fgf signaling suggests a two-step model of otic placode induction. Development (2006) 1.31
BMP signaling is necessary for patterning the sensory and nonsensory regions of the developing mammalian cochlea. J Neurosci (2010) 1.22
In vitro growth and differentiation of mammalian sensory hair cell progenitors: a requirement for EGF and periotic mesenchyme. Dev Biol (2004) 1.18
Expression of mouse Foxi class genes in early craniofacial development. Dev Dyn (2004) 1.16
SOX9 controls epithelial branching by activating RET effector genes during kidney development. Hum Mol Genet (2011) 1.13
Tissue-specific roles of Tbx1 in the development of the outer, middle and inner ear, defective in 22q11DS patients. Hum Mol Genet (2006) 1.13
Canonical Notch signaling is not necessary for prosensory induction in the mouse cochlea: insights from a conditional mutant of RBPjkappa. J Neurosci (2011) 1.09
Dlx gene expression during chick inner ear development. J Comp Neurol (2005) 1.02
Conditional deletion of Atoh1 reveals distinct critical periods for survival and function of hair cells in the organ of Corti. J Neurosci (2013) 0.99
Distinct roles for hindbrain and paraxial mesoderm in the induction and patterning of the inner ear revealed by a study of vitamin-A-deficient quail. Dev Biol (2005) 0.99
Expression of the Foxi2 and Foxi3 transcription factors during development of chicken sensory placodes and pharyngeal arches. Gene Expr Patterns (2012) 0.86
Molecular basis of inner ear induction. Curr Top Dev Biol (2003) 0.85
Analysis of FGF-dependent and FGF-independent pathways in otic placode induction. PLoS One (2013) 0.85
The role of Atonal transcription factors in the development of mechanosensitive cells. Semin Cell Dev Biol (2013) 0.85
Segregating neural and mechanosensory fates in the developing ear: patterning, signaling, and transcriptional control. Cell Tissue Res (2014) 0.83
EGFR signaling is required for regenerative proliferation in the cochlea: conservation in birds and mammals. Dev Biol (2012) 0.82
Congenital aural atresia associated with agenesis of internal carotid artery in a girl with a FOXI3 deletion. Am J Med Genet A (2015) 0.82
Overview of genetic tools and techniques to study Notch signaling in mice. Methods Mol Biol (2014) 0.76