Roselyn J Eisenberg

Author PubWeight™ 103.69‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Crystal structure of glycoprotein B from herpes simplex virus 1. Science 2006 5.57
2 Immunogenicity of a highly attenuated MVA smallpox vaccine and protection against monkeypox. Nature 2004 3.65
3 Structure of unliganded HSV gD reveals a mechanism for receptor-mediated activation of virus entry. EMBO J 2005 2.95
4 Crystal structure of the conserved herpesvirus fusion regulator complex gH-gL. Nat Struct Mol Biol 2010 2.45
5 Bimolecular complementation reveals that glycoproteins gB and gH/gL of herpes simplex virus interact with each other during cell fusion. Proc Natl Acad Sci U S A 2007 2.43
6 Protective immunity to vaccinia virus induced by vaccination with multiple recombinant outer membrane proteins of intracellular and extracellular virions. J Virol 2004 2.21
7 Glycoprotein D receptor-dependent, low-pH-independent endocytic entry of herpes simplex virus type 1. J Virol 2005 2.07
8 Structure-based analysis of the herpes simplex virus glycoprotein D binding site present on herpesvirus entry mediator HveA (HVEM). J Virol 2002 2.03
9 Combinations of polyclonal or monoclonal antibodies to proteins of the outer membranes of the two infectious forms of vaccinia virus protect mice against a lethal respiratory challenge. J Virol 2005 1.94
10 Specific association of glycoprotein B with lipid rafts during herpes simplex virus entry. J Virol 2003 1.92
11 Cascade of events governing cell-cell fusion induced by herpes simplex virus glycoproteins gD, gH/gL, and gB. J Virol 2010 1.91
12 The soluble ectodomain of herpes simplex virus gD contains a membrane-proximal pro-fusion domain and suffices to mediate virus entry. Proc Natl Acad Sci U S A 2004 1.89
13 Herpes simplex virus glycoprotein B binds to cell surfaces independently of heparan sulfate and blocks virus entry. J Virol 2005 1.85
14 Mutational evidence of internal fusion loops in herpes simplex virus glycoprotein B. J Virol 2007 1.79
15 Structure-based mutagenesis of herpes simplex virus glycoprotein D defines three critical regions at the gD-HveA/HVEM binding interface. J Virol 2003 1.78
16 Comparative usage of herpesvirus entry mediator A and nectin-1 by laboratory strains and clinical isolates of herpes simplex virus. Virology 2004 1.73
17 Bimolecular complementation defines functional regions of Herpes simplex virus gB that are involved with gH/gL as a necessary step leading to cell fusion. J Virol 2010 1.70
18 Herpes simplex virus glycoprotein B associates with target membranes via its fusion loops. J Virol 2009 1.65
19 Antigenic and mutational analyses of herpes simplex virus glycoprotein B reveal four functional regions. J Virol 2007 1.56
20 Characterization of a heparan sulfate octasaccharide that binds to herpes simplex virus type 1 glycoprotein D. J Biol Chem 2002 1.53
21 Structure of herpes simplex virus glycoprotein D bound to the human receptor nectin-1. PLoS Pathog 2011 1.53
22 Physical and immunological characterization of a recombinant secreted form of the membrane protein encoded by the vaccinia virus L1R gene. Virology 2005 1.49
23 Epitope-mapping studies define two major neutralization sites on the vaccinia virus extracellular enveloped virus glycoprotein B5R. J Virol 2005 1.44
24 Chimpanzee/human mAbs to vaccinia virus B5 protein neutralize vaccinia and smallpox viruses and protect mice against vaccinia virus. Proc Natl Acad Sci U S A 2006 1.44
25 A protein-based smallpox vaccine protects mice from vaccinia and ectromelia virus challenges when given as a prime and single boost. Vaccine 2006 1.43
26 Potential nectin-1 binding site on herpes simplex virus glycoprotein d. J Virol 2005 1.39
27 In vivo role of nectin-1 in entry of herpes simplex virus type 1 (HSV-1) and HSV-2 through the vaginal mucosa. J Virol 2004 1.39
28 Contribution of cysteine residues to the structure and function of herpes simplex virus gH/gL. Virology 2005 1.27
29 Cellular localization of nectin-1 and glycoprotein D during herpes simplex virus infection. J Virol 2003 1.21
30 Effects of herpes simplex virus on structure and function of nectin-1/HveC. J Virol 2002 1.20
31 Entry of herpes simplex virus type 1 into primary sensory neurons in vitro is mediated by Nectin-1/HveC. J Virol 2003 1.20
32 The orthopoxvirus type I IFN binding protein is essential for virulence and an effective target for vaccination. J Exp Med 2008 1.19
33 Kinetic analysis of glycoprotein C of herpes simplex virus types 1 and 2 binding to heparin, heparan sulfate, and complement component C3b. Virology 2002 1.19
34 Herpes simplex virus type 1 evades the effects of antibody and complement in vivo. J Virol 2002 1.19
35 Characterization of chimpanzee/human monoclonal antibodies to vaccinia virus A33 glycoprotein and its variola virus homolog in vitro and in a vaccinia virus mouse protection model. J Virol 2007 1.19
36 Function of herpes simplex virus type 1 gD mutants with different receptor-binding affinities in virus entry and fusion. J Virol 2003 1.18
37 Alpha-herpesvirus glycoprotein D interaction with sensory neurons triggers formation of varicosities that serve as virus exit sites. J Cell Biol 2006 1.17
38 The herpes simplex virus receptor nectin-1 is down-regulated after trans-interaction with glycoprotein D. Virology 2008 1.17
39 Epitope mapping of herpes simplex virus type 2 gH/gL defines distinct antigenic sites, including some associated with biological function. J Virol 2006 1.16
40 N-terminal mutants of herpes simplex virus type 2 gH are transported without gL but require gL for function. J Virol 2007 1.14
41 Structural basis of local, pH-dependent conformational changes in glycoprotein B from herpes simplex virus type 1. J Virol 2010 1.14
42 Structure-function analysis of herpes simplex virus type 1 gD and gH-gL: clues from gDgH chimeras. J Virol 2003 1.13
43 Crystallization and preliminary diffraction studies of the ectodomain of the envelope glycoprotein D from herpes simplex virus 1 alone and in complex with the ectodomain of the human receptor HveA. Acta Crystallogr D Biol Crystallogr 2002 1.11
44 Mucosal administration of CpG oligodeoxynucleotide elicits strong CC and CXC chemokine responses in the vagina and serves as a potent Th1-tilting adjuvant for recombinant gD2 protein vaccination against genital herpes. J Virol 2006 1.09
45 Engineered disulfide bonds in herpes simplex virus type 1 gD separate receptor binding from fusion initiation and viral entry. J Virol 2007 1.09
46 Vaccinia virus exhibits cell-type-dependent entry characteristics. Virology 2009 1.09
47 Nectin-1/HveC Mediates herpes simplex virus type 1 entry into primary human sensory neurons and fibroblasts. J Neurovirol 2005 1.08
48 Regulation of herpes simplex virus gB-induced cell-cell fusion by mutant forms of gH/gL in the absence of gD and cellular receptors. MBio 2013 1.07
49 Targeting of antigen to the herpesvirus entry mediator augments primary adaptive immune responses. Nat Med 2008 1.07
50 Herpes simplex virus glycoprotein D interferes with binding of herpesvirus entry mediator to its ligands through downregulation and direct competition. J Virol 2010 1.07
51 Capturing the herpes simplex virus core fusion complex (gB-gH/gL) in an acidic environment. J Virol 2011 1.07
52 Disparity between levels of in vitro neutralization of vaccinia virus by antibody to the A27 protein and protection of mice against intranasal challenge. J Virol 2008 1.01
53 Dominance and diversity in the primary human CD4 T cell response to replication-competent vaccinia virus. J Immunol 2007 1.00
54 The structure of herpesvirus fusion glycoprotein B-bilayer complex reveals the protein-membrane and lateral protein-protein interaction. Structure 2013 1.00
55 Stable association of herpes simplex virus with target membranes is triggered by low pH in the presence of the gD receptor, HVEM. J Virol 2006 1.00
56 Blocking immune evasion as a novel approach for prevention and treatment of herpes simplex virus infection. J Virol 2003 1.00
57 Antibody-induced conformational changes in herpes simplex virus glycoprotein gD reveal new targets for virus neutralization. J Virol 2011 0.99
58 Antibody responses to vaccinia membrane proteins after smallpox vaccination. J Infect Dis 2007 0.99
59 Vaccinia virus L1 binds to cell surfaces and blocks virus entry independently of glycosaminoglycans. Virology 2009 0.99
60 A protein-based smallpox vaccine protects non-human primates from a lethal monkeypox virus challenge. Vaccine 2010 0.98
61 Fusion between perinuclear virions and the outer nuclear membrane requires the fusogenic activity of herpes simplex virus gB. J Virol 2009 0.93
62 Rapid progression to simian AIDS can be accompanied by selection of CD4-independent gp120 variants with impaired ability to bind CD4. J Virol 2002 0.93
63 Entry of herpesviruses into cells: the enigma variations. Adv Exp Med Biol 2013 0.92
64 Dual split protein-based fusion assay reveals that mutations to herpes simplex virus (HSV) glycoprotein gB alter the kinetics of cell-cell fusion induced by HSV entry glycoproteins. J Virol 2013 0.92
65 Mechanism of neutralization of herpes simplex virus by antibodies directed at the fusion domain of glycoprotein B. J Virol 2013 0.92
66 Antibody against extracellular vaccinia virus (EV) protects mice through complement and Fc receptors. PLoS One 2011 0.92
67 Effects of herpes simplex virus type 2 glycoprotein vaccines and CLDC adjuvant on genital herpes infection in the guinea pig. Vaccine 2011 0.90
68 An HSV-1 gD mutant virus as an entry-impaired live virus vaccine. Vaccine 2008 0.87
69 Major neutralizing sites on vaccinia virus glycoprotein B5 are exposed differently on variola virus ortholog B6. J Virol 2007 0.86
70 Induction of conformational changes at the N-terminus of herpes simplex virus glycoprotein D upon binding to HVEM and nectin-1. Virology 2013 0.81
71 The membrane-proximal region (MPR) of herpes simplex virus gB regulates association of the fusion loops with lipid membranes. MBio 2012 0.81
72 Displacement of the C terminus of herpes simplex virus gD is sufficient to expose the fusion-activating interfaces on gD. J Virol 2013 0.80
73 Role of sulfatide in vaccinia virus infection. Biol Cell 2011 0.80
74 Spatiotemporal changes of the herpes simplex virus entry receptor nectin-1 in murine brain during postnatal development. J Neurovirol 2006 0.78
75 The myristate moiety and amino terminus of vaccinia virus l1 constitute a bipartite functional region needed for entry. J Virol 2012 0.77
76 The mature virion of ectromelia virus, a pathogenic poxvirus, is capable of intrahepatic spread and can serve as a target for delayed therapy. J Virol 2013 0.75