Published in Ann N Y Acad Sci on April 01, 2004
The mammalian Scribble polarity protein regulates epithelial cell adhesion and migration through E-cadherin. J Cell Biol (2005) 2.28
Mechanisms in photodynamic therapy: part two-cellular signaling, cell metabolism and modes of cell death. Photodiagnosis Photodyn Ther (2005) 1.52
Metastatic progression of prostate cancer and e-cadherin regulation by zeb1 and SRC family kinases. Am J Pathol (2011) 1.33
E-cadherin inhibits cell surface localization of the pro-migratory 5T4 oncofetal antigen in mouse embryonic stem cells. Mol Biol Cell (2007) 1.26
In vivo selection for metastasis promoting genes in the mouse. Proc Natl Acad Sci U S A (2007) 1.20
DNA and histone methylation in gastric carcinogenesis. World J Gastroenterol (2013) 1.03
Gastrokine 1 functions as a tumor suppressor by inhibition of epithelial-mesenchymal transition in gastric cancers. J Cancer Res Clin Oncol (2011) 1.01
Soluble L1CAM promotes breast cancer cell adhesion and migration in vitro, but not invasion. Cancer Cell Int (2010) 1.01
Novel pancreatic cancer cell lines derived from genetically engineered mouse models of spontaneous pancreatic adenocarcinoma: applications in diagnosis and therapy. PLoS One (2013) 1.01
TGFBI expression reduces in vitro and in vivo metastatic potential of lung and breast tumor cells. Cancer Lett (2011) 0.98
Loss of function of e-cadherin in embryonic stem cells and the relevance to models of tumorigenesis. J Oncol (2010) 0.97
Cadherin-11, a marker of the mesenchymal phenotype, regulates glioblastoma cell migration and survival in vivo. Mol Cancer Res (2012) 0.97
Antineoplastic effects of rosiglitazone and PPARgamma transactivation in neuroblastoma cells. Br J Cancer (2006) 0.94
p110 CUX1 homeodomain protein stimulates cell migration and invasion in part through a regulatory cascade culminating in the repression of E-cadherin and occludin. J Biol Chem (2009) 0.93
The "two-faced" effects of reactive oxygen species and the lipid peroxidation product 4-hydroxynonenal in the hallmarks of cancer. Cancers (Basel) (2010) 0.93
NCAM induces CaMKIIalpha-mediated RPTPalpha phosphorylation to enhance its catalytic activity and neurite outgrowth. J Cell Biol (2008) 0.90
Crosstalk between beta-catenin and snail in the induction of epithelial to mesenchymal transition in hepatocarcinoma: role of the ERK1/2 pathway. Int J Mol Sci (2013) 0.89
Vascular endothelial growth factor receptor-1 activation promotes migration and invasion of breast cancer cells through epithelial-mesenchymal transition. PLoS One (2013) 0.89
Crossroads of integrins and cadherins in epithelia and stroma remodeling. Cell Adh Migr (2012) 0.88
Akt-dependent cell size regulation by the adhesion molecule on glia occurs independently of phosphatidylinositol 3-kinase and Rheb signaling. Mol Cell Biol (2005) 0.85
Expression of E-cadherin, N-cadherin and snail and their correlation with clinicopathological variants: an immunohistochemical study of 132 invasive ductal breast carcinomas in Egypt. Clinics (Sao Paulo) (2011) 0.83
Pancreatic cancer cell glycosylation regulates cell adhesion and invasion through the modulation of α2β1 integrin and E-cadherin function. PLoS One (2014) 0.82
CEACAM1 in cervical cancer and precursor lesions: association with human papillomavirus infection. J Histochem Cytochem (2006) 0.81
The role of estrogen receptor β in prostate cancer. Mol Med (2014) 0.80
Neural cell adhesion molecule isoform 140 declines with rise of WHO grade in human gliomas and serves as indicator for the invasion zone of multiform glioblastomas and brain metastases. J Cancer Res Clin Oncol (2010) 0.79
EGF receptor-targeted nanocarriers for enhanced cancer treatment. Nanomedicine (Lond) (2012) 0.79
Effect of Furin inhibitor on lung adenocarcinoma cell growth and metastasis. Cancer Cell Int (2014) 0.79
Fine mapping for Weaver syndrome in Brown Swiss cattle and the identification of 41 concordant mutations across NRCAM, PNPLA8 and CTTNBP2. PLoS One (2013) 0.79
Tight Junctions and the Tumor Microenvironment. Curr Pathobiol Rep (2016) 0.78
The role of epithelial-mesenchymal transition drivers ZEB1 and ZEB2 in mediating docetaxel-resistant prostate cancer. Mol Oncol (2017) 0.76
DRP-1, ezrin and E-cadherin expression and the association with esophageal squamous cell carcinoma. Oncol Lett (2014) 0.75
Analysis of metastasis suppressing function of E-cadherin in gastric cancer cells by RNAi. World J Gastroenterol (2005) 0.75
NCAM affects directional lamellipodia formation of BMSCs via β1 integrin signal-mediated cofilin activity. Mol Cell Biochem (2017) 0.75
Proteomic characterization of paired non-malignant and malignant African-American prostate epithelial cell lines distinguishes them by structural proteins. BMC Cancer (2017) 0.75
Cell adhesion and signalling by cadherins and Ig-CAMs in cancer. Nat Rev Cancer (2004) 6.73
EMT, the cytoskeleton, and cancer cell invasion. Cancer Metastasis Rev (2009) 5.61
Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation. Nature (2008) 5.15
Tumor invasion in the absence of epithelial-mesenchymal transition: podoplanin-mediated remodeling of the actin cytoskeleton. Cancer Cell (2006) 3.28
Mechanisms of motility in metastasizing cells. Mol Cancer Res (2010) 2.42
Pre-EMTing metastasis? Recapitulation of morphogenetic processes in cancer. Clin Exp Metastasis (2007) 2.41
Hepatocyte growth factor induces cell scattering through MAPK/Egr-1-mediated upregulation of Snail. EMBO J (2006) 2.38
Further pharmacological and genetic evidence for the efficacy of PlGF inhibition in cancer and eye disease. Cell (2010) 2.26
EMT as the ultimate survival mechanism of cancer cells. Semin Cancer Biol (2012) 2.22
[Lys40(Ahx-DTPA-111In)NH2]exendin-4, a very promising ligand for glucagon-like peptide-1 (GLP-1) receptor targeting. J Nucl Med (2006) 2.15
Sprouty proteins, masterminds of receptor tyrosine kinase signaling. Angiogenesis (2008) 1.95
Molecular networks that regulate cancer metastasis. Semin Cancer Biol (2012) 1.88
Sox4 is a master regulator of epithelial-mesenchymal transition by controlling Ezh2 expression and epigenetic reprogramming. Cancer Cell (2013) 1.85
Angiopoietins in angiogenesis. Cancer Lett (2012) 1.69
Exendin-4-based radiopharmaceuticals for glucagonlike peptide-1 receptor PET/CT and SPECT/CT. J Nucl Med (2010) 1.67
NCAM-induced focal adhesion assembly: a functional switch upon loss of E-cadherin. EMBO J (2008) 1.62
Mouse models of breast cancer metastasis. Breast Cancer Res (2006) 1.62
The angiogenic switch in carcinogenesis. Semin Cancer Biol (2009) 1.59
Distinct mechanisms of tumor invasion and metastasis. Trends Mol Med (2007) 1.48
Tumor VEGF:VEGFR2 autocrine feed-forward loop triggers angiogenesis in lung cancer. J Clin Invest (2013) 1.41
Cadherins and the tumour progression: is it all in a switch? Cancer Lett (2002) 1.37
[Lys40(Ahx-DTPA-111In)NH2]-Exendin-4 is a highly efficient radiotherapeutic for glucagon-like peptide-1 receptor-targeted therapy for insulinoma. Clin Cancer Res (2007) 1.35
Klf4 is a transcriptional regulator of genes critical for EMT, including Jnk1 (Mapk8). PLoS One (2013) 1.33
Increased tumor cell dissemination and cellular senescence in the absence of beta1-integrin function. EMBO J (2007) 1.32
Corrupt policemen: inflammatory cells promote tumor angiogenesis. Curr Opin Oncol (2009) 1.29
Reduction of circulating soluble Flt-1 alleviates preeclampsia-like symptoms in a mouse model. J Cell Mol Med (2009) 1.24
The binding of NCAM to FGFR1 induces a specific cellular response mediated by receptor trafficking. J Cell Biol (2009) 1.23
Neural cell adhesion molecule regulates the cellular response to fibroblast growth factor. J Cell Sci (2007) 1.23
Myeloid cells contribute to tumor lymphangiogenesis. PLoS One (2009) 1.22
A CD44v6 peptide reveals a role of CD44 in VEGFR-2 signaling and angiogenesis. Blood (2009) 1.22
Distinct roles of vascular endothelial growth factor-D in lymphangiogenesis and metastasis. Am J Pathol (2007) 1.16
Concepts of metastasis in flux: the stromal progression model. Semin Cancer Biol (2012) 1.10
Suppressive effects of vascular endothelial growth factor-B on tumor growth in a mouse model of pancreatic neuroendocrine tumorigenesis. PLoS One (2010) 1.09
The sialomucin CD34 is a marker of lymphatic endothelial cells in human tumors. Am J Pathol (2006) 1.09
Rebuilding cancer metastasis in the mouse. Mol Oncol (2013) 1.08
Molecular mechanisms of lymphangiogenesis in development and cancer. Int J Dev Biol (2011) 1.05
Loss of neural cell adhesion molecule induces tumor metastasis by up-regulating lymphangiogenesis. Cancer Res (2004) 1.04
Split personalities: the agonistic antagonist Sprouty. Nat Cell Biol (2003) 1.03
A pro-inflammatory signature mediates FGF2-induced angiogenesis. J Cell Mol Med (2009) 1.03
Transcription factor Dlx2 protects from TGFβ-induced cell-cycle arrest and apoptosis. EMBO J (2011) 0.99
Angiopoietin-1 and -2 exert antagonistic functions in tumor angiogenesis, yet both induce lymphangiogenesis. Cancer Res (2011) 0.99
VEGF-mediated angiogenesis links EMT-induced cancer stemness to tumor initiation. Cancer Res (2014) 0.97
Tead2 expression levels control the subcellular distribution of Yap and Taz, zyxin expression and epithelial-mesenchymal transition. J Cell Sci (2014) 0.96
Placental growth factor-1 attenuates vascular endothelial growth factor-A-dependent tumor angiogenesis during beta cell carcinogenesis. Cancer Res (2007) 0.96
Targeting tumor-associated endothelial cells: anti-VEGFR2 immunoliposomes mediate tumor vessel disruption and inhibit tumor growth. Clin Cancer Res (2011) 0.95
The tyrosine phosphatase PTPN14 is a negative regulator of YAP activity. PLoS One (2013) 0.95
Temporal effects of Sprouty on lung morphogenesis. Dev Biol (2003) 0.93
Overexpression of vascular endothelial growth factor-A165 enhances tumor angiogenesis but not metastasis during beta-cell carcinogenesis. Cancer Res (2002) 0.93
Modulation of endocrine pancreas development but not beta-cell carcinogenesis by Sprouty4. Mol Cancer Res (2008) 0.93
Novel technologies and recent advances in metastasis research. Int J Dev Biol (2004) 0.90
Recent advances in cancer research: mouse models of tumorigenesis. Biochim Biophys Acta (2002) 0.89
Proangiogenic factor PlGF programs CD11b(+) myelomonocytes in breast cancer during differentiation of their hematopoietic progenitors. Cancer Res (2011) 0.88
Myeloid cells and lymphangiogenesis. Cold Spring Harb Perspect Med (2012) 0.88
Tenascin-C downregulates wnt inhibitor dickkopf-1, promoting tumorigenesis in a neuroendocrine tumor model. Cell Rep (2013) 0.87
Differential effects of the vascular endothelial growth factor receptor inhibitor PTK787/ZK222584 on tumor angiogenesis and tumor lymphangiogenesis. Mol Cancer Ther (2009) 0.86
Sprouty proteins: antagonists of endothelial cell signaling and more. Thromb Haemost (2003) 0.86
Py2T murine breast cancer cells, a versatile model of TGFβ-induced EMT in vitro and in vivo. PLoS One (2012) 0.85
Cancer: division of labour. Nature (2007) 0.84
PI3K signalling is required for a TGFβ-induced epithelial-mesenchymal-like transition (EMT-like) in human melanoma cells. Exp Dermatol (2014) 0.83
A functional interaction between sprouty proteins and caveolin-1. J Biol Chem (2006) 0.83
Kras in metastatic colorectal cancer. Swiss Med Wkly (2010) 0.81
Antitumorigenic and antiinsulinogenic effects of calcitriol on insulinoma cells and solid beta-cell tumors. Endocrinology (2002) 0.80
The IGF/IGF-1 receptor signaling pathway as a potential target for cancer therapy. Drug Resist Updat (1999) 0.79
Hedgehog inhibition with cyclopamine represses tumor growth and prolongs survival in a transgenic mouse model of islet cell tumors. Ann Surg (2011) 0.79
Repression of malignant tumor progression upon pharmacologic IGF1R blockade in a mouse model of insulinoma. Mol Cancer Res (2012) 0.79
Protein 4.1B in mouse islets of Langerhans and beta-cell tumorigenesis. Histochem Cell Biol (2003) 0.79
Sprouty2 expression controls endothelial monolayer integrity and quiescence. Angiogenesis (2012) 0.78
A bioluminescent mouse model of pancreatic {beta}-cell carcinogenesis. Carcinogenesis (2010) 0.78
Synergism of peptide receptor-targeted Auger electron radiation therapy with anti-angiogenic compounds in a mouse model of neuroendocrine tumors. EJNMMI Res (2014) 0.77
Paralemmin-1 is expressed in lymphatic endothelial cells and modulates cell migration, cell maturation and tumor lymphangiogenesis. Angiogenesis (2013) 0.76
Molecular pathways involved in the antineoplastic effects of calcitriol on insulinoma cells. Endocrinology (2003) 0.75
An immature B cell population from peripheral blood serves as surrogate marker for monitoring tumor angiogenesis and anti-angiogenic therapy in mouse models. Angiogenesis (2015) 0.75
Moderate antiangiogenic activity by local, transgenic expression of endostatin in Rip1Tag2 transgenic mice. J Leukoc Biol (2006) 0.75