Squire J Booker

Author PubWeight™ 45.06‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A radically different mechanism for S-adenosylmethionine-dependent methyltransferases. Science 2011 2.55
2 Reconstitution of ThiC in thiamine pyrimidine biosynthesis expands the radical SAM superfamily. Nat Chem Biol 2008 1.96
3 Lipoyl synthase requires two equivalents of S-adenosyl-L-methionine to synthesize one equivalent of lipoic acid. Biochemistry 2004 1.67
4 Detection of formate, rather than carbon monoxide, as the stoichiometric coproduct in conversion of fatty aldehydes to alkanes by a cyanobacterial aldehyde decarbonylase. J Am Chem Soc 2011 1.62
5 Structural basis for methyl transfer by a radical SAM enzyme. Science 2011 1.61
6 Evidence for only oxygenative cleavage of aldehydes to alk(a/e)nes and formate by cyanobacterial aldehyde decarbonylases. Biochemistry 2012 1.60
7 Conversion of fatty aldehydes to alka(e)nes and formate by a cyanobacterial aldehyde decarbonylase: cryptic redox by an unusual dimetal oxygenase. J Am Chem Soc 2011 1.54
8 Substrate positioning controls the partition between halogenation and hydroxylation in the aliphatic halogenase, SyrB2. Proc Natl Acad Sci U S A 2009 1.47
9 In vitro characterization of AtsB, a radical SAM formylglycine-generating enzyme that contains three [4Fe-4S] clusters. Biochemistry 2008 1.46
10 Insight into the polar reactivity of the onium chalcogen analogues of S-adenosyl-L-methionine. Biochemistry 2004 1.36
11 Mechanistic investigations of lipoic acid biosynthesis in Escherichia coli: both sulfur atoms in lipoic acid are contributed by the same lipoyl synthase polypeptide. J Am Chem Soc 2005 1.36
12 Escherichia coli lipoyl synthase binds two distinct [4Fe-4S] clusters per polypeptide. Biochemistry 2004 1.35
13 Characterization of RimO, a new member of the methylthiotransferase subclass of the radical SAM superfamily. Biochemistry 2009 1.33
14 Cyanobacterial alkane biosynthesis further expands the catalytic repertoire of the ferritin-like 'di-iron-carboxylate' proteins. Curr Opin Chem Biol 2011 1.19
15 A consensus mechanism for Radical SAM-dependent dehydrogenation? BtrN contains two [4Fe-4S] clusters. Biochemistry 2010 1.13
16 X-ray structure of an AdoMet radical activase reveals an anaerobic solution for formylglycine posttranslational modification. Proc Natl Acad Sci U S A 2013 1.08
17 Cfr and RlmN contain a single [4Fe-4S] cluster, which directs two distinct reactivities for S-adenosylmethionine: methyl transfer by SN2 displacement and radical generation. J Am Chem Soc 2011 1.07
18 RlmN and AtsB as models for the overproduction and characterization of radical SAM proteins. Methods Enzymol 2012 1.03
19 Identification and function of auxiliary iron-sulfur clusters in radical SAM enzymes. Biochim Biophys Acta 2012 1.02
20 Isotope and elemental effects indicate a rate-limiting methyl transfer as the initial step in the reaction catalyzed by Escherichia coli cyclopropane fatty acid synthase. Biochemistry 2004 1.01
21 Mechanistic and functional versatility of radical SAM enzymes. F1000 Biol Rep 2010 0.98
22 Further characterization of Cys-type and Ser-type anaerobic sulfatase maturating enzymes suggests a commonality in the mechanism of catalysis. Biochemistry 2013 0.95
23 A substrate radical intermediate in catalysis by the antibiotic resistance protein Cfr. Nat Chem Biol 2013 0.93
24 Escherichia coli quinolinate synthetase does indeed harbor a [4Fe-4S] cluster. J Am Chem Soc 2005 0.93
25 X-ray analysis of butirosin biosynthetic enzyme BtrN redefines structural motifs for AdoMet radical chemistry. Proc Natl Acad Sci U S A 2013 0.93
26 Escherichia coli L-serine deaminase requires a [4Fe-4S] cluster in catalysis. J Biol Chem 2004 0.91
27 Expression, purification, and physical characterization of Escherichia coli lipoyl(octanoyl)transferase. Protein Expr Purif 2005 0.91
28 Characterization of quinolinate synthases from Escherichia coli, Mycobacterium tuberculosis, and Pyrococcus horikoshii indicates that [4Fe-4S] clusters are common cofactors throughout this class of enzymes. Biochemistry 2008 0.87
29 Spectroscopic and Electrochemical Characterization of the Iron-Sulfur and Cobalamin Cofactors of TsrM, an Unusual Radical S-Adenosylmethionine Methylase. J Am Chem Soc 2016 0.86
30 A high-throughput screen for quorum-sensing inhibitors that target acyl-homoserine lactone synthases. Proc Natl Acad Sci U S A 2013 0.85
31 Evidence for a catalytically and kinetically competent enzyme-substrate cross-linked intermediate in catalysis by lipoyl synthase. Biochemistry 2014 0.85
32 Characterization of a cross-linked protein-nucleic acid substrate radical in the reaction catalyzed by RlmN. J Am Chem Soc 2014 0.83
33 Biochemistry: The ylide has landed. Nature 2013 0.82
34 The activity of Escherichia coli cyclopropane fatty acid synthase depends on the presence of bicarbonate. J Am Chem Soc 2005 0.81
35 Regulation of the activity of Escherichia coli quinolinate synthase by reversible disulfide-bond formation. Biochemistry 2008 0.80
36 Efficient delivery of long-chain fatty aldehydes from the Nostoc punctiforme acyl-acyl carrier protein reductase to its cognate aldehyde-deformylating oxygenase. Biochemistry 2015 0.77
37 Electrochemical Resolution of the [4Fe-4S] Centers of the AdoMet Radical Enzyme BtrN: Evidence of Proton Coupling and an Unusual, Low-Potential Auxiliary Cluster. J Am Chem Soc 2015 0.76
38 Transformations of the FeS Clusters of the Methylthiotransferases MiaB and RimO, Detected by Direct Electrochemistry. Biochemistry 2016 0.76
39 Enzymology: Radical break-up, blissful make-up. Nat Chem Biol 2011 0.75
40 The Radical S-Adenosylmethionine Methylase NosN Catalyzes both C1 Transfer and Formation of the Ester Linkage of the Side-Ring System during the Biosynthesis of Nosiheptide. J Am Chem Soc 2017 0.75