Comprehensive evaluation of tamoxifen sequential biotransformation by the human cytochrome P450 system in vitro: prominent roles for CYP3A and CYP2D6.

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Published in J Pharmacol Exp Ther on May 24, 2004


Zeruesenay Desta1, Bryan A Ward, Nadia V Soukhova, David A Flockhart

Author Affiliations

1: Indiana University School of Medicine, Department of Medicine/Division of Clinical Pharmacology, 1001 West 10th street, WD Myers Bldg., W7123, Indianapolis, IN 46202, USA.

Associated clinical trials:

Genotyping and Phenotyping of CYP2D6 Breast Cancer Patients on Tamoxifen | NCT03504631

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