Published in Cell on May 28, 2004
Pannexin-1 mediates large pore formation and interleukin-1beta release by the ATP-gated P2X7 receptor. EMBO J (2006) 8.12
The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis. Nat Immunol (2009) 7.80
The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation. Cell Death Differ (2007) 7.74
Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells. Nat Immunol (2005) 6.81
Horror autoinflammaticus: the molecular pathophysiology of autoinflammatory disease (*). Annu Rev Immunol (2009) 5.91
Programmed cell death in animal development and disease. Cell (2011) 5.07
Innate immunity against Francisella tularensis is dependent on the ASC/caspase-1 axis. J Exp Med (2005) 5.00
Cytosolic recognition of flagellin by mouse macrophages restricts Legionella pneumophila infection. J Exp Med (2006) 4.86
The NLR gene family: a standard nomenclature. Immunity (2008) 4.77
Differential regulation of caspase-1 activation, pyroptosis, and autophagy via Ipaf and ASC in Shigella-infected macrophages. PLoS Pathog (2007) 4.73
A pilot study of IL-1 inhibition by anakinra in acute gout. Arthritis Res Ther (2007) 4.65
Differential requirement for the activation of the inflammasome for processing and release of IL-1beta in monocytes and macrophages. Blood (2008) 4.63
NF-kappaB is a negative regulator of IL-1beta secretion as revealed by genetic and pharmacological inhibition of IKKbeta. Cell (2007) 4.56
Pathogen recognition and inflammatory signaling in innate immune defenses. Clin Microbiol Rev (2009) 4.55
Yellow fever vaccine induces integrated multilineage and polyfunctional immune responses. J Exp Med (2008) 4.21
Role of the caspase-1 inflammasome in Salmonella typhimurium pathogenesis. J Exp Med (2006) 3.76
The death domain superfamily in intracellular signaling of apoptosis and inflammation. Annu Rev Immunol (2007) 3.59
An essential role for the NLRP3 inflammasome in host defense against the human fungal pathogen Candida albicans. Cell Host Microbe (2009) 3.52
Influenza virus activates inflammasomes via its intracellular M2 ion channel. Nat Immunol (2010) 3.45
A NOD2-NALP1 complex mediates caspase-1-dependent IL-1beta secretion in response to Bacillus anthracis infection and muramyl dipeptide. Proc Natl Acad Sci U S A (2008) 3.27
The amphioxus genome illuminates vertebrate origins and cephalochordate biology. Genome Res (2008) 3.04
Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity. Science (2014) 2.99
Multiple Nod-like receptors activate caspase 1 during Listeria monocytogenes infection. J Immunol (2008) 2.87
Internalization and phagosome escape required for Francisella to induce human monocyte IL-1beta processing and release. Proc Natl Acad Sci U S A (2005) 2.82
Innate immunity in the central nervous system. J Clin Invest (2012) 2.77
Candida albicans morphogenesis and host defence: discriminating invasion from colonization. Nat Rev Microbiol (2011) 2.70
The B30.2 domain of pyrin, the familial Mediterranean fever protein, interacts directly with caspase-1 to modulate IL-1beta production. Proc Natl Acad Sci U S A (2006) 2.59
IL-1beta processing in host defense: beyond the inflammasomes. PLoS Pathog (2010) 2.54
Staphylococcus aureus evades lysozyme-based peptidoglycan digestion that links phagocytosis, inflammasome activation, and IL-1beta secretion. Cell Host Microbe (2010) 2.49
IL-32 synergizes with nucleotide oligomerization domain (NOD) 1 and NOD2 ligands for IL-1beta and IL-6 production through a caspase 1-dependent mechanism. Proc Natl Acad Sci U S A (2005) 2.46
TLR5 and Ipaf: dual sensors of bacterial flagellin in the innate immune system. Semin Immunopathol (2007) 2.42
Uptake of particulate vaccine adjuvants by dendritic cells activates the NALP3 inflammasome. Proc Natl Acad Sci U S A (2009) 2.42
Caspase-1-mediated activation of interleukin-1beta (IL-1beta) and IL-18 contributes to innate immune defenses against Salmonella enterica serovar Typhimurium infection. Infect Immun (2006) 2.35
Apoptosis: a mechanism of acute and chronic liver injury. Gut (2005) 2.33
Inflammatory arthritis in caspase 1 gene-deficient mice: contribution of proteinase 3 to caspase 1-independent production of bioactive interleukin-1beta. Arthritis Rheum (2009) 2.23
Chronic inflammation: importance of NOD2 and NALP3 in interleukin-1beta generation. Clin Exp Immunol (2007) 2.12
A common allosteric site and mechanism in caspases. Proc Natl Acad Sci U S A (2006) 2.12
Caspases: pharmacological manipulation of cell death. J Clin Invest (2005) 2.10
Macrophage activation redirects yersinia-infected host cell death from apoptosis to caspase-1-dependent pyroptosis. PLoS Pathog (2007) 2.01
Caspase-7 activation by the Nlrc4/Ipaf inflammasome restricts Legionella pneumophila infection. PLoS Pathog (2009) 1.99
NLRP3/cryopyrin is necessary for interleukin-1beta (IL-1beta) release in response to hyaluronan, an endogenous trigger of inflammation in response to injury. J Biol Chem (2009) 1.91
Tissue-mediated control of immunopathology in coeliac disease. Nat Rev Immunol (2009) 1.91
NALP inflammasomes: a central role in innate immunity. Semin Immunopathol (2007) 1.91
Innate immune recognition of Mycobacterium tuberculosis. Clin Dev Immunol (2011) 1.90
No death without life: vital functions of apoptotic effectors. Cell Death Differ (2008) 1.80
Cutting edge: Cytosolic bacterial DNA activates the inflammasome via Aim2. J Immunol (2010) 1.77
P2X7-dependent release of interleukin-1beta and nociception in the spinal cord following lipopolysaccharide. J Neurosci (2010) 1.55
NF-kappaB activation by the Toll-IL-1 receptor domain protein MyD88 adapter-like is regulated by caspase-1. Proc Natl Acad Sci U S A (2007) 1.54
Bacterial manipulation of innate immunity to promote infection. Nat Rev Microbiol (2010) 1.53
Inflammasome mRNA expression in human monocytes during early septic shock. Am J Respir Crit Care Med (2008) 1.52
Histone deacetylase inhibitors prevent exocytosis of interleukin-1beta-containing secretory lysosomes: role of microtubules. Blood (2006) 1.48
NALP1 influences susceptibility to human congenital toxoplasmosis, proinflammatory cytokine response, and fate of Toxoplasma gondii-infected monocytic cells. Infect Immun (2010) 1.46
Caspase-1 activation in macrophages infected with Yersinia pestis KIM requires the type III secretion system effector YopJ. Infect Immun (2008) 1.44
Inflammasome up-regulation and activation in dysferlin-deficient skeletal muscle. Am J Pathol (2010) 1.41
Initial delay in the immune response to Francisella tularensis is followed by hypercytokinemia characteristic of severe sepsis and correlating with upregulation and release of damage-associated molecular patterns. Infect Immun (2008) 1.41
Inflammasome-dependent caspase-1 activation in cervical epithelial cells stimulates growth of the intracellular pathogen Chlamydia trachomatis. J Biol Chem (2009) 1.37
Interleukin-32 induces the differentiation of monocytes into macrophage-like cells. Proc Natl Acad Sci U S A (2008) 1.37
Protease-activated drug development. Theranostics (2012) 1.36
Interactions of tumor cells with dendritic cells: balancing immunity and tolerance. Cell Death Differ (2007) 1.35
Anthrax lethal toxin triggers the formation of a membrane-associated inflammasome complex in murine macrophages. Infect Immun (2009) 1.34
The use of the R6 transgenic mouse models of Huntington's disease in attempts to develop novel therapeutic strategies. NeuroRx (2005) 1.33
Novel genes dramatically alter regulatory network topology in amphioxus. Genome Biol (2008) 1.32
Fungal zymosan and mannan activate the cryopyrin inflammasome. J Biol Chem (2009) 1.32
Co-regulation of NF-kappaB and inflammasome-mediated inflammatory responses by myxoma virus pyrin domain-containing protein M013. PLoS Pathog (2009) 1.32
Autophagy and inflammatory cell death, partners of innate immunity. Autophagy (2005) 1.30
The mitochondrial death pathway: a promising therapeutic target in diseases. J Cell Mol Med (2009) 1.30
ATP-dependent activation of an inflammasome in primary gingival epithelial cells infected by Porphyromonas gingivalis. Cell Microbiol (2009) 1.29
Regulatory molecules involved in inflammasome formation with special reference to a key mediator protein, ASC. Semin Immunopathol (2007) 1.29
Caspase-1 promiscuity is counterbalanced by rapid inactivation of processed enzyme. J Biol Chem (2011) 1.27
ATP release and purinergic signaling in NLRP3 inflammasome activation. Front Immunol (2013) 1.23
Physiological functions of caspases beyond cell death. Am J Pathol (2006) 1.22
Apoptosis-related genes change their expression with age and hearing loss in the mouse cochlea. Apoptosis (2008) 1.21
Hepatitis C virus activates interleukin-1β via caspase-1-inflammasome complex. J Gen Virol (2011) 1.20
Activation and regulation of cellular inflammasomes: gaps in our knowledge for central nervous system injury. J Cereb Blood Flow Metab (2014) 1.20
Role of IL-1 beta in the development of human T(H)17 cells: lesson from NLPR3 mutated patients. PLoS One (2011) 1.17
C-type lectin receptor-induced NF-κB activation in innate immune and inflammatory responses. Cell Mol Immunol (2012) 1.17
Role of the inflammasome, IL-1β, and IL-18 in bacterial infections. ScientificWorldJournal (2011) 1.15
Scientific and clinical challenges in sepsis. Curr Pharm Des (2009) 1.14
Flightless-I regulates proinflammatory caspases by selectively modulating intracellular localization and caspase activity. J Cell Biol (2008) 1.14
Innate immunity in inflammatory bowel disease. World J Gastroenterol (2007) 1.13
Nod-like receptors: cytosolic watchdogs for immunity against pathogens. PLoS Pathog (2007) 1.12
The Central Role of Anti-IL-1 Blockade in the Treatment of Monogenic and Multi-Factorial Autoinflammatory Diseases. Front Immunol (2013) 1.11
Immunostimulatory activity of haptenated proteins. Proc Natl Acad Sci U S A (2009) 1.10
Intestinal mucositis: the role of the Bcl-2 family, p53 and caspases in chemotherapy-induced damage. Support Care Cancer (2006) 1.10
M867, a novel selective inhibitor of caspase-3 enhances cell death and extends tumor growth delay in irradiated lung cancer models. PLoS One (2008) 1.10
Inflammasomes: sensors of metabolic stresses for vascular inflammation. Front Biosci (Landmark Ed) (2013) 1.09
Restriction of Legionella pneumophila replication in macrophages requires concerted action of the transcriptional regulators Irf1 and Irf8 and nod-like receptors Naip5 and Nlrc4. Infect Immun (2009) 1.08
NLRP3 inflammasome: from a danger signal sensor to a regulatory node of oxidative stress and inflammatory diseases. Redox Biol (2015) 1.08
Receptor-interacting protein (RIP) kinase family. Cell Mol Immunol (2010) 1.07
Mechanisms of intestinal inflammation and development of associated cancers: lessons learned from mouse models. Mutat Res (2010) 1.06
Non-apoptotic functions of apoptosis-regulatory proteins. EMBO Rep (2012) 1.06
Proliferative versus apoptotic functions of caspase-8 Hetero or homo: the caspase-8 dimer controls cell fate. Biochim Biophys Acta (2011) 1.04
Death by caspase dimerization. Adv Exp Med Biol (2012) 1.04
Caspases leave the beaten track: caspase-mediated activation of NF-kappaB. J Cell Biol (2006) 1.04
Pattern recognition receptor-dependent mechanisms of acute lung injury. Mol Med (2009) 1.04
A molecular signature of normal breast epithelial and stromal cells from Li-Fraumeni syndrome mutation carriers. Oncotarget (2010) 1.03
Expression and regulation of the NALP3 inflammasome complex in periodontal diseases. Clin Exp Immunol (2009) 1.03
Allergic contact dermatitis: epidemiology, molecular mechanisms, in vitro methods and regulatory aspects. Current knowledge assembled at an international workshop at BfR, Germany. Cell Mol Life Sci (2011) 1.02
Innate sensors of influenza virus: clues to developing better intranasal vaccines. Expert Rev Vaccines (2008) 1.01
Asbestos-induced cellular and molecular alteration of immunocompetent cells and their relationship with chronic inflammation and carcinogenesis. J Biomed Biotechnol (2012) 1.01
Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature (2006) 24.43
The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta. Mol Cell (2002) 20.11
Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus. Nature (2005) 17.47
Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. Science (2008) 16.54
NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder. Immunity (2004) 13.55
A role for mitochondria in NLRP3 inflammasome activation. Nature (2010) 13.21
The inflammasomes: guardians of the body. Annu Rev Immunol (2009) 12.89
Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes. Cell (2003) 11.07
Thioredoxin-interacting protein links oxidative stress to inflammasome activation. Nat Immunol (2009) 9.24
Intracellular pattern recognition receptors in the host response. Nature (2006) 8.04
The inflammasome: a danger sensing complex triggering innate immunity. Curr Opin Immunol (2007) 6.81
Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors. Nat Med (2009) 6.73
RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kappa B activation. Nat Immunol (2004) 5.74
Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence. Nature (2009) 5.00
Identification of bacterial muramyl dipeptide as activator of the NALP3/cryopyrin inflammasome. Curr Biol (2004) 4.89
A pilot study of IL-1 inhibition by anakinra in acute gout. Arthritis Res Ther (2007) 4.65
The PIDDosome, a protein complex implicated in activation of caspase-2 in response to genotoxic stress. Science (2004) 4.17
NLRs join TLRs as innate sensors of pathogens. Trends Immunol (2005) 4.12
Type I interferon inhibits interleukin-1 production and inflammasome activation. Immunity (2011) 3.97
Cutting edge: alum adjuvant stimulates inflammatory dendritic cells through activation of the NALP3 inflammasome. J Immunol (2008) 3.66
Inhibitor of apoptosis proteins limit RIP3 kinase-dependent interleukin-1 activation. Immunity (2012) 3.51
PIDD mediates NF-kappaB activation in response to DNA damage. Cell (2005) 3.48
The molecular architecture of the TNF superfamily. Trends Biochem Sci (2002) 3.39
Inhibition of interleukin 1 receptor/Toll-like receptor signaling through the alternatively spliced, short form of MyD88 is due to its failure to recruit IRAK-4. J Exp Med (2003) 3.24
Toll-like receptors and RNA helicases: two parallel ways to trigger antiviral responses. Mol Cell (2006) 3.23
Inflammasome components NALP 1 and 3 show distinct but separate expression profiles in human tissues suggesting a site-specific role in the inflammatory response. J Histochem Cytochem (2006) 3.20
CARMA1 is a critical lipid raft-associated regulator of TCR-induced NF-kappa B activation. Nat Immunol (2002) 3.16
The long form of FLIP is an activator of caspase-8 at the Fas death-inducing signaling complex. J Biol Chem (2002) 2.75
Interactions of tumor necrosis factor (TNF) and TNF receptor family members in the mouse and human. J Biol Chem (2006) 2.75
Activation of the IL-1beta-processing inflammasome is involved in contact hypersensitivity. J Invest Dermatol (2007) 2.73
A crucial function of SGT1 and HSP90 in inflammasome activity links mammalian and plant innate immune responses. Nat Immunol (2007) 2.68
T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes. Nature (2009) 2.59
Association of mutations in the NALP3/CIAS1/PYPAF1 gene with a broad phenotype including recurrent fever, cold sensitivity, sensorineural deafness, and AA amyloidosis. Arthritis Rheum (2002) 2.58
The RIP kinases: crucial integrators of cellular stress. Trends Biochem Sci (2005) 2.56
cFLIP regulation of lymphocyte activation and development. Nat Rev Immunol (2006) 2.53
Two adjacent trimeric Fas ligands are required for Fas signaling and formation of a death-inducing signaling complex. Mol Cell Biol (2003) 2.50
Uric acid is a danger signal activating NALP3 inflammasome in lung injury inflammation and fibrosis. Am J Respir Crit Care Med (2009) 2.45
Recruitment of TNF receptor 1 to lipid rafts is essential for TNFalpha-mediated NF-kappaB activation. Immunity (2003) 2.41
TRADD protein is an essential component of the RIG-like helicase antiviral pathway. Immunity (2008) 2.37
Life and death decisions: secondary complexes and lipid rafts in TNF receptor family signal transduction. Immunity (2004) 2.36
Innate immunity: cytoplasmic DNA sensing by the AIM2 inflammasome. Curr Biol (2009) 2.34
Tollip regulates proinflammatory responses to interleukin-1 and lipopolysaccharide. Mol Cell Biol (2006) 2.33
Function of TRADD in tumor necrosis factor receptor 1 signaling and in TRIF-dependent inflammatory responses. Nat Immunol (2008) 2.32
Innate immune sensing of modified vaccinia virus Ankara (MVA) is mediated by TLR2-TLR6, MDA-5 and the NALP3 inflammasome. PLoS Pathog (2009) 2.24
NMR structure of the apoptosis- and inflammation-related NALP1 pyrin domain. Structure (2003) 2.15
N-terminal fragment of c-FLIP(L) processed by caspase 8 specifically interacts with TRAF2 and induces activation of the NF-kappaB signaling pathway. Mol Cell Biol (2004) 2.11
Nanoparticles activate the NLR pyrin domain containing 3 (Nlrp3) inflammasome and cause pulmonary inflammation through release of IL-1α and IL-1β. Proc Natl Acad Sci U S A (2010) 2.09
Identification of proteoglycans as the APRIL-specific binding partners. J Exp Med (2005) 2.03
Caspase-independent cell death in T lymphocytes. Nat Immunol (2003) 1.99
NALP inflammasomes: a central role in innate immunity. Semin Immunopathol (2007) 1.91
Type I IFN controls chikungunya virus via its action on nonhematopoietic cells. J Exp Med (2010) 1.86
TACI, unlike BAFF-R, is solely activated by oligomeric BAFF and APRIL to support survival of activated B cells and plasmablasts. Blood (2007) 1.85
Caspase-2 activation in the absence of PIDDosome formation. J Cell Biol (2009) 1.74
Autoproteolysis of PIDD marks the bifurcation between pro-death caspase-2 and pro-survival NF-kappaB pathway. EMBO J (2006) 1.74
DAI/ZBP1 recruits RIP1 and RIP3 through RIP homotypic interaction motifs to activate NF-kappaB. EMBO Rep (2009) 1.72
NLRC4 inflammasomes in dendritic cells regulate noncognate effector function by memory CD8⁺ T cells. Nat Immunol (2012) 1.62
Differential expression of NLRP3 among hematopoietic cells. J Immunol (2011) 1.60
The inflammasome. Curr Biol (2005) 1.58
New insights into the mechanism of IL-1beta maturation. Curr Opin Immunol (2003) 1.54
The NLRP3 inflammasome is differentially activated by pneumolysin variants and contributes to host defense in pneumococcal pneumonia. J Immunol (2011) 1.54
Overexpression of Helicard, a CARD-containing helicase cleaved during apoptosis, accelerates DNA degradation. Curr Biol (2002) 1.50
Schistosoma mansoni triggers Dectin-2, which activates the Nlrp3 inflammasome and alters adaptive immune responses. Proc Natl Acad Sci U S A (2010) 1.50
Pathogenic Vibrio activate NLRP3 inflammasome via cytotoxins and TLR/nucleotide-binding oligomerization domain-mediated NF-kappa B signaling. J Immunol (2010) 1.43
The role of interleukin-1 and the inflammasome in gout: implications for therapy. Arthritis Rheum (2007) 1.39
Structure of the PRYSPRY-domain: implications for autoinflammatory diseases. FEBS Lett (2005) 1.36
The caspase 8 inhibitor c-FLIP(L) modulates T-cell receptor-induced proliferation but not activation-induced cell death of lymphocytes. Mol Cell Biol (2002) 1.36
TCR-induced NF-kappaB activation: a crucial role for Carma1, Bcl10 and MALT1. Trends Immunol (2003) 1.32
BAFF is a survival and maturation factor for mouse B cells. Eur J Immunol (2002) 1.31
BAFF production by antigen-presenting cells provides T cell co-stimulation. Int Immunol (2004) 1.29
The role of potassium in inflammasome activation by bacteria. J Biol Chem (2010) 1.29
RIP4 (DIK/PKK), a novel member of the RIP kinase family, activates NF-kappa B and is processed during apoptosis. EMBO Rep (2002) 1.23
From inflammasomes to fevers, crystals and hypertension: how basic research explains inflammatory diseases. Trends Mol Med (2007) 1.20
The role of the inflammasome in nonmyeloid cells. J Clin Immunol (2010) 1.18
Intracellular trafficking of interleukin-1 receptor I requires Tollip. Curr Biol (2006) 1.18
BAFF and the regulation of B cell survival. Immunol Lett (2003) 1.18
Activation of the NLRP3 inflammasome by Mycobacterium tuberculosis is uncoupled from susceptibility to active tuberculosis. Eur J Immunol (2011) 1.18
Inflammasome-activated caspase 7 cleaves PARP1 to enhance the expression of a subset of NF-κB target genes. Mol Cell (2012) 1.17
Cleavage of mitochondrial antiviral signaling protein in the liver of patients with chronic hepatitis C correlates with a reduced activation of the endogenous interferon system. Hepatology (2010) 1.15
NLRC5 deficiency selectively impairs MHC class I- dependent lymphocyte killing by cytotoxic T cells. J Immunol (2012) 1.14
The anti-apoptotic factor Bcl-2 can functionally substitute for the B cell survival but not for the marginal zone B cell differentiation activity of BAFF. Eur J Immunol (2004) 1.08
Danger signaling through the inflammasome acts as a master switch between tolerance and sensitization. J Immunol (2008) 1.08
Protein-based therapeutic approaches targeting death receptors. Cell Death Differ (2003) 1.08
Defective death receptor signaling as a cause of tumor immune escape. Semin Cancer Biol (2002) 1.04
Cytotoxins of the human pathogen Aeromonas hydrophila trigger, via the NLRP3 inflammasome, caspase-1 activation in macrophages. Eur J Immunol (2010) 1.02
Cellular FLIP long form augments caspase activity and death of T cells through heterodimerization with and activation of caspase-8. J Immunol (2005) 1.01
The mycobacterial cord factor adjuvant analogue trehalose-6,6'-dibehenate (TDB) activates the Nlrp3 inflammasome. Immunobiology (2012) 0.96
NALP3 is not necessary for early protection against experimental tuberculosis. Immunobiology (2010) 0.94
Intracellular localization of keratinocyte Fas ligand explains lack of cytolytic activity under physiological conditions. J Biol Chem (2002) 0.94
Cellular FLIP long form-transgenic mice manifest a Th2 cytokine bias and enhanced allergic airway inflammation. J Immunol (2004) 0.93
Intracellular pattern-recognition receptors. Adv Drug Deliv Rev (2007) 0.92
NLRP3 suppresses NK cell-mediated responses to carcinogen-induced tumors and metastases. Cancer Res (2012) 0.92
NLRP3 promotes inflammation-induced skin cancer but is dispensable for asbestos-induced mesothelioma. Immunol Cell Biol (2012) 0.91
Identification of a basic surface area of the FADD death effector domain critical for apoptotic signaling. FEBS Lett (2002) 0.89
Expression level of c-FLIP versus Fas determines susceptibility to Fas ligand-induced cell death in murine thymoma EL-4 cells. Exp Cell Res (2002) 0.87
Ubiquitination of the Epstein-Barr virus-encoded latent membrane protein 1 depends on the integrity of the TRAF binding site. Oncogene (2003) 0.86
DEteCTINg fungal pathogens. Nat Immunol (2007) 0.84
IRAK2 takes its place in TLR signaling. Nat Immunol (2008) 0.84
The combination of chemotherapy and intraperitoneal MegaFas Ligand improves treatment of ovarian carcinoma. Gynecol Oncol (2007) 0.81
Thogoto virus infection induces sustained type I interferon responses that depend on RIG-I-like helicase signaling of conventional dendritic cells. J Virol (2010) 0.79