Published in Microbiol Mol Biol Rev on June 01, 2004
Non-classical protein secretion in bacteria. BMC Microbiol (2005) 3.17
An accessory protein required for anchoring and assembly of amyloid fibres in B. subtilis biofilms. Mol Microbiol (2011) 2.17
Mapping the pathways to staphylococcal pathogenesis by comparative secretomics. Microbiol Mol Biol Rev (2006) 1.93
A protein secretion pathway critical for Mycobacterium tuberculosis virulence is conserved and functional in Mycobacterium smegmatis. J Bacteriol (2005) 1.81
LocateP: genome-scale subcellular-location predictor for bacterial proteins. BMC Bioinformatics (2008) 1.64
Transient heterogeneity in extracellular protease production by Bacillus subtilis. Mol Syst Biol (2008) 1.60
Listeria monocytogenes surface proteins: from genome predictions to function. Microbiol Mol Biol Rev (2007) 1.59
The Rok protein of Bacillus subtilis represses genes for cell surface and extracellular functions. J Bacteriol (2005) 1.49
Bacillus subtilis: from soil bacterium to super-secreting cell factory. Microb Cell Fact (2013) 1.46
Differential proteomic analysis of the Bacillus anthracis secretome: distinct plasmid and chromosome CO2-dependent cross talk mechanisms modulate extracellular proteolytic activities. J Bacteriol (2006) 1.28
Identification of in vivo-expressed immunogenic proteins by serological proteome analysis of the Bacillus anthracis secretome. Infect Immun (2007) 1.28
Extracellular proteins in pea root tip and border cell exudates. Plant Physiol (2006) 1.27
Systems-wide temporal proteomic profiling in glucose-starved Bacillus subtilis. Nat Commun (2010) 1.19
RNase Y in Bacillus subtilis: a Natively disordered protein that is the functional equivalent of RNase E from Escherichia coli. J Bacteriol (2011) 1.15
High-level expression and secretion of methyl parathion hydrolase in Bacillus subtilis WB800. Appl Environ Microbiol (2005) 1.15
Role of FliF and FliI of Listeria monocytogenes in flagellar assembly and pathogenicity. Infect Immun (2005) 1.13
Emerging vaccine informatics. J Biomed Biotechnol (2011) 1.12
Through the wall: extracellular vesicles in Gram-positive bacteria, mycobacteria and fungi. Nat Rev Microbiol (2015) 1.09
Membrane proteases in the bacterial protein secretion and quality control pathway. Microbiol Mol Biol Rev (2012) 1.08
Optimization of protease secretion in Bacillus subtilis and Bacillus licheniformis by screening of homologous and heterologous signal peptides. Appl Environ Microbiol (2010) 1.07
Characterization of XynC from Bacillus subtilis subsp. subtilis strain 168 and analysis of its role in depolymerization of glucuronoxylan. J Bacteriol (2006) 1.07
Nonclassical protein secretion by Bacillus subtilis in the stationary phase is not due to cell lysis. J Bacteriol (2011) 1.06
Staphylococcal major autolysin (Atl) is involved in excretion of cytoplasmic proteins. J Biol Chem (2010) 1.06
Masquerading microbial pathogens: capsular polysaccharides mimic host-tissue molecules. FEMS Microbiol Rev (2014) 1.05
Towards the development of Bacillus subtilis as a cell factory for membrane proteins and protein complexes. Microb Cell Fact (2008) 1.05
Simple, fast and high-efficiency transformation system for directed evolution of cellulase in Bacillus subtilis. Microb Biotechnol (2011) 1.03
Enzymatic activities and functional interdependencies of Bacillus subtilis lipoteichoic acid synthesis enzymes. Mol Microbiol (2010) 1.03
Sec-secretion and sortase-mediated anchoring of proteins in Gram-positive bacteria. Biochim Biophys Acta (2013) 1.03
Genomic analysis of thermophilic Bacillus coagulans strains: efficient producers for platform bio-chemicals. Sci Rep (2014) 1.01
Type I signal peptidase and protein secretion in Staphylococcus aureus. J Bacteriol (2012) 1.01
Genome-wide analysis of signal peptide functionality in Lactobacillus plantarum WCFS1. BMC Genomics (2009) 1.01
Characterization of abn2 (yxiA), encoding a Bacillus subtilis GH43 arabinanase, Abn2, and its role in arabino-polysaccharide degradation. J Bacteriol (2008) 1.00
Self-inducible Bacillus subtilis expression system for reliable and inexpensive protein production by high-cell-density fermentation. Appl Environ Microbiol (2011) 0.99
Type I signal peptidase and protein secretion in Staphylococcus epidermidis. J Bacteriol (2010) 0.99
Daptomycin versus Friulimicin B: in-depth profiling of Bacillus subtilis cell envelope stress responses. Antimicrob Agents Chemother (2009) 0.98
Comparative study of the extracellular proteome of Sulfolobus species reveals limited secretion. Extremophiles (2009) 0.98
From genome to toxicity: a combinatory approach highlights the complexity of enterotoxin production in Bacillus cereus. Front Microbiol (2015) 0.98
High-yield intra- and extracellular protein production using Bacillus megaterium. Appl Environ Microbiol (2010) 0.97
Lipoteichoic acid is a major component of the Bacillus subtilis periplasm. J Bacteriol (2008) 0.95
Bacillus cereus cytotoxins Hbl, Nhe and CytK are secreted via the Sec translocation pathway. BMC Microbiol (2010) 0.95
Comparative proteomic analysis of extracellular proteins of Clostridium perfringens type A and type C strains. Infect Immun (2010) 0.95
Comprehensive characterization of methicillin-resistant Staphylococcus aureus subsp. aureus COL secretome by two-dimensional liquid chromatography and mass spectrometry. Mol Cell Proteomics (2010) 0.95
High levels of DegU-P activate an Esat-6-like secretion system in Bacillus subtilis. PLoS One (2013) 0.94
A disulfide bond-containing alkaline phosphatase triggers a BdbC-dependent secretion stress response in Bacillus subtilis. Appl Environ Microbiol (2006) 0.92
Characterization of Acp, a peptidoglycan hydrolase of Clostridium perfringens with N-acetylglucosaminidase activity that is implicated in cell separation and stress-induced autolysis. J Bacteriol (2010) 0.91
Transcription factor σB plays an important role in the production of extracellular membrane-derived vesicles in Listeria monocytogenes. PLoS One (2013) 0.90
Modulation of thiol-disulfide oxidoreductases for increased production of disulfide-bond-containing proteins in Bacillus subtilis. Appl Environ Microbiol (2008) 0.90
Comparative secretome analysis suggests low plant cell wall degrading capacity in Frankia symbionts. BMC Genomics (2008) 0.90
Quantitative proteomics of the Neisseria gonorrhoeae cell envelope and membrane vesicles for the discovery of potential therapeutic targets. Mol Cell Proteomics (2014) 0.90
Complementation of the Lactococcus lactis secretion machinery with Bacillus subtilis SecDF improves secretion of staphylococcal nuclease. Appl Environ Microbiol (2006) 0.89
The role of calcium ions in the stability and instability of a thermolysin-like protease. Protein Sci (2011) 0.88
Biotic interactions in the rhizosphere: a diverse cooperative enterprise for plant productivity. Plant Physiol (2014) 0.88
Development of a LytE-based high-density surface display system in Bacillus subtilis. Microb Biotechnol (2008) 0.87
Growth of Acidithiobacillus Ferrooxidans ATCC 23270 in Thiosulfate Under Oxygen-Limiting Conditions Generates Extracellular Sulfur Globules by Means of a Secreted Tetrathionate Hydrolase. Front Microbiol (2011) 0.87
Subcellular localization of extracytoplasmic proteins in monoderm bacteria: rational secretomics-based strategy for genomic and proteomic analyses. PLoS One (2012) 0.87
Processing of a membrane protein required for cell-to-cell signaling during endospore formation in Bacillus subtilis. J Bacteriol (2008) 0.87
How are the non-classically secreted bacterial proteins released into the extracellular milieu? Curr Microbiol (2013) 0.86
The Blueprint of a Minimal Cell: MiniBacillus. Microbiol Mol Biol Rev (2016) 0.85
Analysis of the secretomes of Paracoccidioides mycelia and yeast cells. PLoS One (2012) 0.85
High external pH enables more efficient secretion of alkaline α-amylase AmyK38 by Bacillus subtilis. Microb Cell Fact (2012) 0.85
Engineering the xylan utilization system in Bacillus subtilis for production of acidic Xylooligosaccharides. Appl Environ Microbiol (2013) 0.85
YneA, an SOS-induced inhibitor of cell division in Bacillus subtilis, is regulated posttranslationally and requires the transmembrane region for activity. J Bacteriol (2010) 0.85
Excreted Cytoplasmic Proteins Contribute to Pathogenicity in Staphylococcus aureus. Infect Immun (2016) 0.85
Applications of thiol-disulfide oxidoreductases for optimized in vivo production of functionally active proteins in Bacillus. Appl Microbiol Biotechnol (2009) 0.84
Identification and characterization of a novel polysaccharide deacetylase C (PdaC) from Bacillus subtilis. J Biol Chem (2012) 0.84
Functional implementation of the posttranslational SecB-SecA protein-targeting pathway in Bacillus subtilis. Appl Environ Microbiol (2011) 0.84
Overcoming function annotation errors in the Gram-positive pathogen Streptococcus suis by a proteomics-driven approach. BMC Genomics (2008) 0.84
Diminished exoproteome of Frankia spp. in culture and symbiosis. Appl Environ Microbiol (2009) 0.84
Intermolecular interactions of the malate synthase of Paracoccidioides spp. BMC Microbiol (2013) 0.84
Role of the cell wall microenvironment in expression of a heterologous SpaP-S1 fusion protein by Streptococcus gordonii. Appl Environ Microbiol (2010) 0.83
Two-dimensional gel electrophoresis in bacterial proteomics. Protein Cell (2012) 0.83
A novel strategy for protein production using non-classical secretion pathway in Bacillus subtilis. Microb Cell Fact (2016) 0.82
High-salinity growth conditions promote Tat-independent secretion of Tat substrates in Bacillus subtilis. Appl Environ Microbiol (2012) 0.82
Analysis of the secretome and identification of novel constituents from culture filtrate of bacillus Calmette-Guerin using high-resolution mass spectrometry. Mol Cell Proteomics (2013) 0.82
The twin-arginine signal peptide of Bacillus subtilis YwbN can direct either Tat- or Sec-dependent secretion of different cargo proteins: secretion of active subtilisin via the B. subtilis Tat pathway. Appl Environ Microbiol (2008) 0.82
A homolog of Bacillus subtilis trigger factor in Listeria monocytogenes is involved in stress tolerance and bacterial virulence. Appl Environ Microbiol (2006) 0.82
Phenotypic characterization of the foldase homologue PrsA in Streptococcus mutans. Mol Oral Microbiol (2012) 0.82
Recovery and characterization of a 30.7-kDa protein from Bacillus licheniformis associated with inhibitory activity against methicillin-resistant Staphylococcus aureus, vancomycin-resistant enterococci, and Listeria monocytogenes. Mar Biotechnol (NY) (2006) 0.82
Molecular engineering of secretory machinery components for high-level secretion of proteins in Bacillus species. J Ind Microbiol Biotechnol (2014) 0.82
Changing a single amino acid in Clostridium perfringens beta-toxin affects the efficiency of heterologous secretion by Bacillus subtilis. Appl Environ Microbiol (2007) 0.81
Modification of the secretion pattern of proteases, inflammatory mediators, and extracellular matrix proteins by human aortic valve is key in severe aortic stenosis. Mol Cell Proteomics (2013) 0.81
Heterologous expression, biochemical characterization, and overproduction of alkaline α-amylase from Bacillus alcalophilus in Bacillus subtilis. Microb Cell Fact (2011) 0.81
Novel expression vector for secretion of cecropin AD in Bacillus subtilis with enhanced antimicrobial activity. Antimicrob Agents Chemother (2009) 0.81
NClassG+: A classifier for non-classically secreted Gram-positive bacterial proteins. BMC Bioinformatics (2011) 0.81
Translational arrest by a prokaryotic signal recognition particle is mediated by RNA interactions. Nat Struct Mol Biol (2015) 0.81
A new potential secretion pathway for recombinant proteins in Bacillus subtilis. Microb Cell Fact (2015) 0.80
Novel modulators controlling entry into sporulation in Bacillus subtilis. J Bacteriol (2013) 0.80
The secretion of an intrinsically disordered protein with different secretion signals in Bacillus subtilis. Curr Microbiol (2013) 0.80
Secretome analysis defines the major role of SecDF in Staphylococcus aureus virulence. PLoS One (2013) 0.80
Extracellular proteome analysis of Leptospira interrogans serovar Lai. OMICS (2013) 0.80
Novel and unique diagnostic biomarkers for Bacillus anthracis infection. Appl Environ Microbiol (2009) 0.80
Specific targeting of the metallophosphoesterase YkuE to the bacillus cell wall requires the twin-arginine translocation system. J Biol Chem (2012) 0.80
The Anabaena sp. PCC 7120 Exoproteome: Taking a Peek outside the Box. Life (Basel) (2015) 0.80
Proteomic evidences for rex regulation of metabolism in toxin-producing Bacillus cereus ATCC 14579. PLoS One (2014) 0.80
An internal hydrophobic helical domain of Bacillus subtilis enolase is essential but not sufficient as a non-cleavable signal for its secretion. Biochem Biophys Res Commun (2014) 0.79
Degradation of extracytoplasmic catalysts for protein folding in Bacillus subtilis. Appl Environ Microbiol (2013) 0.79
Degradation of the twin-arginine translocation substrate YwbN by extracytoplasmic proteases of Bacillus subtilis. Appl Environ Microbiol (2012) 0.79
Homogeneity and heterogeneity in amylase production by Bacillus subtilis under different growth conditions. Microb Cell Fact (2016) 0.79
Excretion of cytoplasmic proteins in Staphylococcus is most likely not due to cell lysis. Curr Genet (2015) 0.79
Requirement of signal peptidase ComC and thiol-disulfide oxidoreductase DsbA for optimal cell surface display of pseudopilin ComGC in Staphylococcus aureus. Appl Environ Microbiol (2012) 0.78
The complete genome sequence of the gram-positive bacterium Bacillus subtilis. Nature (1997) 33.47
Type III protein secretion systems in bacterial pathogens of animals and plants. Microbiol Mol Biol Rev (1998) 17.27
The complete general secretory pathway in gram-negative bacteria. Microbiol Rev (1993) 16.84
Essential Bacillus subtilis genes. Proc Natl Acad Sci U S A (2003) 14.01
How signal sequences maintain cleavage specificity. J Mol Biol (1984) 11.03
Prediction of transmembrane alpha-helices in prokaryotic membrane proteins: the dense alignment surface method. Protein Eng (1997) 8.25
The signal peptide. J Membr Biol (1990) 7.94
Common principles of protein translocation across membranes. Science (1996) 7.00
Sorting of protein A to the staphylococcal cell wall. Cell (1992) 6.48
Purification and characterization of a low-molecular-mass T-cell antigen secreted by Mycobacterium tuberculosis. Infect Immun (1995) 6.43
A temperature-dependent switch from chaperone to protease in a widely conserved heat shock protein. Cell (1999) 4.78
Contribution of novel choline-binding proteins to adherence, colonization and immunogenicity of Streptococcus pneumoniae. Mol Microbiol (1997) 4.78
Acute infection and macrophage subversion by Mycobacterium tuberculosis require a specialized secretion system. Proc Natl Acad Sci U S A (2003) 4.64
Cell wall sorting signals in surface proteins of gram-positive bacteria. EMBO J (1993) 4.51
Structure of the cell wall anchor of surface proteins in Staphylococcus aureus. Science (1995) 4.27
Biochemical and genetic characterization of a competence pheromone from B. subtilis. Cell (1994) 4.23
Chromosomal location of mutations affecting sucrose metabolism in Bacillus subtilis Marburg. Mol Gen Genet (1972) 4.14
YidC mediates membrane protein insertion in bacteria. Nature (2000) 4.01
A proteomic view on genome-based signal peptide predictions. Genome Res (2001) 3.96
Purification and characterization of sortase, the transpeptidase that cleaves surface proteins of Staphylococcus aureus at the LPXTG motif. Proc Natl Acad Sci U S A (1999) 3.90
Signal peptide-dependent protein transport in Bacillus subtilis: a genome-based survey of the secretome. Microbiol Mol Biol Rev (2000) 3.81
Phosphate starvation-inducible proteins of Bacillus subtilis: proteomics and transcriptional analysis. J Bacteriol (2000) 3.68
Proteolytic cleavage and cell wall anchoring at the LPXTG motif of surface proteins in gram-positive bacteria. Mol Microbiol (1994) 3.57
The ESAT-6/WXG100 superfamily -- and a new Gram-positive secretion system? Trends Microbiol (2002) 3.42
alpha-enolase, a novel strong plasmin(ogen) binding protein on the surface of pathogenic streptococci. J Biol Chem (1998) 3.37
Crystal structure of a bacterial signal peptidase in complex with a beta-lactam inhibitor. Nature (1998) 3.37
The structure of signal peptides from bacterial lipoproteins. Protein Eng (1989) 3.28
An iron-regulated sortase anchors a class of surface protein during Staphylococcus aureus pathogenesis. Proc Natl Acad Sci U S A (2002) 3.23
Type III secretion systems and bacterial flagella: insights into their function from structural similarities. Proc Natl Acad Sci U S A (2003) 3.11
The E. coli signal recognition particle is required for the insertion of a subset of inner membrane proteins. Cell (1997) 3.09
Virulence genes of Clostridium perfringens. Annu Rev Microbiol (1998) 3.01
YidC, the Escherichia coli homologue of mitochondrial Oxa1p, is a component of the Sec translocase. EMBO J (2000) 2.70
Holins: form and function in bacteriophage lysis. FEMS Microbiol Rev (1995) 2.59
Searching for autolysin functions. Characterization of a pneumococcal mutant deleted in the lytA gene. Eur J Biochem (1986) 2.58
The Sec protein-translocation pathway. Trends Microbiol (2001) 2.48
Structure of the core and central channel of bacterial flagella. Nature (1989) 2.39
Differential interactions between a twin-arginine signal peptide and its translocase in Escherichia coli. Mol Cell (2003) 2.35
Comparative proteome analysis of Mycobacterium tuberculosis and Mycobacterium bovis BCG strains: towards functional genomics of microbial pathogens. Mol Microbiol (1999) 2.28
Convergent sensing pathways mediate response to two extracellular competence factors in Bacillus subtilis. Genes Dev (1995) 2.24
Identification and immunogenicity of group A Streptococcus culture supernatant proteins. Infect Immun (2000) 2.21
A new ABC transporter mediating the detachment of lipid-modified proteins from membranes. Nat Cell Biol (2000) 2.16
Protein targeting to the bacterial cytoplasmic membrane. Microbiol Mol Biol Rev (1999) 2.04
Secretion, localization, and antibacterial activity of TasA, a Bacillus subtilis spore-associated protein. J Bacteriol (1999) 1.99
SecA interacts with secretory proteins by recognizing the positive charge at the amino terminus of the signal peptide in Escherichia coli. J Biol Chem (1990) 1.99
The role of autolysins during vegetative growth of Bacillus subtilis 168. Microbiology (1998) 1.97
FtsY, the prokaryotic signal recognition particle receptor homologue, is essential for biogenesis of membrane proteins. J Biol Chem (1997) 1.94
The chemistry and enzymology of the type I signal peptidases. Protein Sci (1997) 1.90
Enterotoxigenic profiles of food-poisoning and food-borne Bacillus cereus strains. J Clin Microbiol (2002) 1.83
Analysis of the peptidoglycan structure of Bacillus subtilis endospores. J Bacteriol (1996) 1.83
Cold shock stress-induced proteins in Bacillus subtilis. J Bacteriol (1996) 1.83
Target cell specificity of a bacteriocin molecule: a C-terminal signal directs lysostaphin to the cell wall of Staphylococcus aureus. EMBO J (1996) 1.82
Influence of amino acid substitutions in the nisin leader peptide on biosynthesis and secretion of nisin by Lactococcus lactis. J Biol Chem (1994) 1.82
Engineering a Bacillus subtilis expression-secretion system with a strain deficient in six extracellular proteases. J Bacteriol (1991) 1.82
A comprehensive two-dimensional map of cytosolic proteins of Bacillus subtilis. Electrophoresis (2001) 1.79
Extracellular proteins of Staphylococcus aureus and the role of SarA and sigma B. Proteomics (2001) 1.75
Mapping and identification of Mycobacterium tuberculosis proteins by two-dimensional gel electrophoresis, microsequencing and immunodetection. Electrophoresis (2000) 1.74
Identification and characterization of the structural and transporter genes for, and the chemical and biological properties of, sublancin 168, a novel lantibiotic produced by Bacillus subtilis 168. J Biol Chem (1998) 1.72
Two-dimensional electrophoresis analysis of the extracellular proteome of Bacillus cereus reveals the importance of the PlcR regulon. Proteomics (2002) 1.69
Anchor structure of staphylococcal surface proteins. A branched peptide that links the carboxyl terminus of proteins to the cell wall. J Biol Chem (1997) 1.68
Discrimination between SRP- and SecA/SecB-dependent substrates involves selective recognition of nascent chains by SRP and trigger factor. EMBO J (2000) 1.68
Protein translocation in the three domains of life: variations on a theme. Cell (1997) 1.67
The PrsA lipoprotein is essential for protein secretion in Bacillus subtilis and sets a limit for high-level secretion. Mol Microbiol (1993) 1.65
Bacillus subtilis histone-like protein, HBsu, is an integral component of a SRP-like particle that can bind the Alu domain of small cytoplasmic RNA. J Biol Chem (1999) 1.64
SecDFyajC forms a heterotetrameric complex with YidC. Mol Microbiol (2002) 1.64
SecB, one small chaperone in the complex milieu of the cell. Cell Mol Life Sci (2002) 1.63
Functional analysis of the secretory precursor processing machinery of Bacillus subtilis: identification of a eubacterial homolog of archaeal and eukaryotic signal peptidases. Genes Dev (1998) 1.62
Translocation of proteins across the cell envelope of Gram-positive bacteria. FEMS Microbiol Rev (2001) 1.61
Conformations of signal peptides induced by lipids suggest initial steps in protein export. Science (1986) 1.58
Signal peptidases in prokaryotes and eukaryotes--a new protease family. Trends Biochem Sci (1992) 1.57
Genome engineering reveals large dispensable regions in Bacillus subtilis. Mol Biol Evol (2003) 1.55
Cloning and expression of gene fragments encoding the choline-binding domain of pneumococcal murein hydrolases. Gene (1990) 1.55
Molecular analysis of three major wall-associated proteins of Bacillus subtilis 168: evidence for processing of the product of a gene encoding a 258 kDa precursor two-domain ligand-binding protein. Mol Microbiol (1993) 1.53
Proteome analysis of Bacillus subtilis extracellular proteins: a two-dimensional protein electrophoretic study. Microbiology (2000) 1.52
A novel two-component regulatory system in Bacillus subtilis for the survival of severe secretion stress. Mol Microbiol (2001) 1.50
A novel class of heat and secretion stress-responsive genes is controlled by the autoregulated CssRS two-component system of Bacillus subtilis. J Bacteriol (2002) 1.48
Protein targeting by the twin-arginine translocation pathway. Nat Rev Mol Cell Biol (2001) 1.48
Functional production and characterization of a fibrin-specific single-chain antibody fragment from Bacillus subtilis: effects of molecular chaperones and a wall-bound protease on antibody fragment production. Appl Environ Microbiol (2002) 1.47
Binding and transport of transforming DNA by Bacillus subtilis: the role of type-IV pilin-like proteins--a review. Gene (1997) 1.47
The role of lipoprotein processing by signal peptidase II in the Gram-positive eubacterium bacillus subtilis. Signal peptidase II is required for the efficient secretion of alpha-amylase, a non-lipoprotein. J Biol Chem (1999) 1.45
Requirement of flhA for swarming differentiation, flagellin export, and secretion of virulence-associated proteins in Bacillus thuringiensis. J Bacteriol (2002) 1.45
SecDF of Bacillus subtilis, a molecular Siamese twin required for the efficient secretion of proteins. J Biol Chem (1998) 1.42
YidC/Oxa1p/Alb3: evolutionarily conserved mediators of membrane protein assembly. FEBS Lett (2001) 1.41
Lytic enzymes associated with defective prophages of Bacillus subtilis: sequencing and characterization of the region comprising the N-acetylmuramoyl-L-alanine amidase gene of prophage PBSX. Microbiology (1994) 1.41
The wprA gene of Bacillus subtilis 168, expressed during exponential growth, encodes a cell-wall-associated protease. Microbiology (1996) 1.41
Glucosaminidase of Bacillus subtilis: cloning, regulation, primary structure and biochemical characterization. Microbiology (1995) 1.40
Two-dimensional electrophoresis for analysis of Mycobacterium tuberculosis culture filtrate and purification and characterization of six novel proteins. Infect Immun (1998) 1.38
TatC is a specificity determinant for protein secretion via the twin-arginine translocation pathway. J Biol Chem (2000) 1.38
The bdbDC operon of Bacillus subtilis encodes thiol-disulfide oxidoreductases required for competence development. J Biol Chem (2001) 1.38
Thiol-disulfide oxidoreductases are essential for the production of the lantibiotic sublancin 168. J Biol Chem (2002) 1.38
Protein targeting signals. Curr Opin Cell Biol (1990) 1.36
SecA is not required for signal recognition particle-mediated targeting and initial membrane insertion of a nascent inner membrane protein. J Biol Chem (1999) 1.36
Bacillus subtilis contains four closely related type I signal peptidases with overlapping substrate specificities. Constitutive and temporally controlled expression of different sip genes. J Biol Chem (1997) 1.35
Life and death of a signal peptide. Nature (1998) 1.35
A new family of peptidyl-prolyl isomerases. Trends Biochem Sci (1995) 1.35
The lytE gene of Bacillus subtilis 168 encodes a cell wall hydrolase. J Bacteriol (1998) 1.34
Bacillus subtilis functional genomics: genome-wide analysis of the DegS-DegU regulon by transcriptomics and proteomics. Mol Genet Genomics (2002) 1.32
Selective contribution of the twin-arginine translocation pathway to protein secretion in Bacillus subtilis. J Biol Chem (2002) 1.32
The pathogenicity of Clostridium difficile. Clin Microbiol Infect (2001) 1.30
Complete genome sequence of Lactobacillus plantarum WCFS1. Proc Natl Acad Sci U S A (2003) 8.40
Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature. Nat Prod Rep (2013) 5.38
Bistability, epigenetics, and bet-hedging in bacteria. Annu Rev Microbiol (2008) 4.74
Condition-dependent transcriptome reveals high-level regulatory architecture in Bacillus subtilis. Science (2012) 4.41
Substrate-controlled succession of marine bacterioplankton populations induced by a phytoplankton bloom. Science (2012) 4.11
Phenotypic variation in bacteria: the role of feedback regulation. Nat Rev Microbiol (2006) 3.73
Guidelines for the next 10 years of proteomics. Proteomics (2006) 3.61
Complete genome sequence of the prototype lactic acid bacterium Lactococcus lactis subsp. cremoris MG1363. J Bacteriol (2007) 3.43
BAGEL3: Automated identification of genes encoding bacteriocins and (non-)bactericidal posttranslationally modified peptides. Nucleic Acids Res (2013) 3.23
Projector 2: contig mapping for efficient gap-closure of prokaryotic genome sequence assemblies. Nucleic Acids Res (2005) 3.22
An alternative bactericidal mechanism of action for lantibiotic peptides that target lipid II. Science (2006) 3.05
Physiological proteomics of the uncultured endosymbiont of Riftia pachyptila. Science (2007) 3.03
LysM, a widely distributed protein motif for binding to (peptido)glycans. Mol Microbiol (2008) 2.98
Bet-hedging and epigenetic inheritance in bacterial cell development. Proc Natl Acad Sci U S A (2008) 2.88
Subcellular sites for bacterial protein export. Mol Microbiol (2004) 2.50
Bacillus subtilis functional genomics: global characterization of the stringent response by proteome and transcriptome analysis. J Bacteriol (2002) 2.47
Peripartum cardiomyopathy as a part of familial dilated cardiomyopathy. Circulation (2010) 2.41
Global network reorganization during dynamic adaptations of Bacillus subtilis metabolism. Science (2012) 2.38
The multiple signaling systems regulating virulence in Pseudomonas aeruginosa. Microbiol Mol Biol Rev (2012) 2.36
Stripping Bacillus: ComK auto-stimulation is responsible for the bistable response in competence development. Mol Microbiol (2005) 2.35
Repair of global regulators in Staphylococcus aureus 8325 and comparative analysis with other clinical isolates. Infect Immun (2010) 2.33
Distinguishing arrhythmogenic right ventricular cardiomyopathy/dysplasia-associated mutations from background genetic noise. J Am Coll Cardiol (2011) 2.31
Controlling competence in Bacillus subtilis: shared use of regulators. Microbiology (2003) 2.30
Phosphatases modulate the bistable sporulation gene expression pattern in Bacillus subtilis. Mol Microbiol (2005) 2.29
Cell wall attachment of a widely distributed peptidoglycan binding domain is hindered by cell wall constituents. J Biol Chem (2003) 2.28
The Lactococcus lactis CodY regulon: identification of a conserved cis-regulatory element. J Biol Chem (2005) 2.11
Biosynthesis and functions of bacillithiol, a major low-molecular-weight thiol in Bacilli. Proc Natl Acad Sci U S A (2010) 2.09
BAGEL2: mining for bacteriocins in genomic data. Nucleic Acids Res (2010) 2.08
Transcriptome and proteome analysis of Bacillus subtilis gene expression in response to superoxide and peroxide stress. Microbiology (2004) 1.96
A generally applicable validation scheme for the assessment of factors involved in reproducibility and quality of DNA-microarray data. BMC Genomics (2005) 1.96
Anaerobic gene expression in Staphylococcus aureus. J Bacteriol (2007) 1.95
Genome2D: a visualization tool for the rapid analysis of bacterial transcriptome data. Genome Biol (2004) 1.93
MicroPreP: a cDNA microarray data pre-processing framework. Appl Bioinformatics (2003) 1.86
Desmin mutations as a cause of right ventricular heart failure affect the intercalated disks. Heart Rhythm (2010) 1.85
Targeted next-generation sequencing can replace Sanger sequencing in clinical diagnostics. Hum Mutat (2013) 1.85
Role of the Fur regulon in iron transport in Bacillus subtilis. J Bacteriol (2006) 1.84
Improving the predictive value of the competence transcription factor (ComK) binding site in Bacillus subtilis using a genomic approach. Nucleic Acids Res (2002) 1.84
Lantibiotic structures as guidelines for the design of peptides that can be modified by lantibiotic enzymes. Biochemistry (2005) 1.84
Identification and functional characterization of cardiac troponin I as a novel disease gene in autosomal dominant dilated cardiomyopathy. Circ Res (2009) 1.83
The relative value of operon predictions. Brief Bioinform (2008) 1.81
Bacillus subtilis as cell factory for pharmaceutical proteins: a biotechnological approach to optimize the host organism. Biochim Biophys Acta (2004) 1.80
Proteomic approach to understanding antibiotic action. Antimicrob Agents Chemother (2003) 1.78
Severe cardiac phenotype with right ventricular predominance in a large cohort of patients with a single missense mutation in the DES gene. Heart Rhythm (2009) 1.78
A comprehensive proteome map of growing Bacillus subtilis cells. Proteomics (2004) 1.78
Quorum quenching by an N-acyl-homoserine lactone acylase from Pseudomonas aeruginosa PAO1. Infect Immun (2006) 1.77
Identification of VceA and VceC, two members of the VjbR regulon that are translocated into macrophages by the Brucella type IV secretion system. Mol Microbiol (2008) 1.76
Influence of the two-component system SaeRS on global gene expression in two different Staphylococcus aureus strains. J Bacteriol (2006) 1.76
Global characterization of disulfide stress in Bacillus subtilis. J Bacteriol (2003) 1.75
The Bacillus subtilis iron-sparing response is mediated by a Fur-regulated small RNA and three small, basic proteins. Proc Natl Acad Sci U S A (2008) 1.74
Polysulfides link H2S to protein thiol oxidation. Antioxid Redox Signal (2013) 1.70
Time-resolved determination of the CcpA regulon of Lactococcus lactis subsp. cremoris MG1363. J Bacteriol (2006) 1.69
Physiological characterization of a heme-deficient mutant of Staphylococcus aureus by a proteomic approach. J Bacteriol (2003) 1.69
Post-translational modification of therapeutic peptides by NisB, the dehydratase of the lantibiotic nisin. Biochemistry (2005) 1.68
FIVA: Functional Information Viewer and Analyzer extracting biological knowledge from transcriptome data of prokaryotes. Bioinformatics (2007) 1.65
Transcriptional profiling of gene expression in response to glucose in Bacillus subtilis: regulation of the central metabolic pathways. Metab Eng (2003) 1.64
CodY of Streptococcus pneumoniae: link between nutritional gene regulation and colonization. J Bacteriol (2007) 1.64
BAGEL: a web-based bacteriocin genome mining tool. Nucleic Acids Res (2006) 1.64
The iturin and fengycin families of lipopeptides are key factors in antagonism of Bacillus subtilis toward Podosphaera fusca. Mol Plant Microbe Interact (2007) 1.61
Transient heterogeneity in extracellular protease production by Bacillus subtilis. Mol Syst Biol (2008) 1.60
Molecular discrimination of responders and nonresponders to anti-TNF alpha therapy in rheumatoid arthritis by etanercept. Arthritis Res Ther (2008) 1.59
Two minimal Tat translocases in Bacillus. Mol Microbiol (2004) 1.58
An ancient pathway combining carbon dioxide fixation with the generation and utilization of a sodium ion gradient for ATP synthesis. PLoS One (2012) 1.57
Effects of phosphorelay perturbations on architecture, sporulation, and spore resistance in biofilms of Bacillus subtilis. J Bacteriol (2006) 1.56
Genome engineering reveals large dispensable regions in Bacillus subtilis. Mol Biol Evol (2003) 1.55
UniFrag and GenomePrimer: selection of primers for genome-wide production of unique amplicons. Bioinformatics (2003) 1.55
Desmoglein-2 and desmocollin-2 mutations in dutch arrhythmogenic right ventricular dysplasia/cardiomypathy patients: results from a multicenter study. Circ Cardiovasc Genet (2009) 1.54
Host imprints on bacterial genomes--rapid, divergent evolution in individual patients. PLoS Pathog (2010) 1.54
Novel surface display system for proteins on non-genetically modified gram-positive bacteria. Appl Environ Microbiol (2006) 1.53
Elevated type I interferon-like activity in a subset of multiple sclerosis patients: molecular basis and clinical relevance. J Neuroinflammation (2012) 1.52
Spx is a global effector impacting stress tolerance and biofilm formation in Staphylococcus aureus. J Bacteriol (2006) 1.52
SpxB regulates O-acetylation-dependent resistance of Lactococcus lactis peptidoglycan to hydrolysis. J Biol Chem (2007) 1.51
Phospholamban R14del mutation in patients diagnosed with dilated cardiomyopathy or arrhythmogenic right ventricular cardiomyopathy: evidence supporting the concept of arrhythmogenic cardiomyopathy. Eur J Heart Fail (2012) 1.51
The influence of agr and sigmaB in growth phase dependent regulation of virulence factors in Staphylococcus aureus. Proteomics (2004) 1.51
Regulation of glutamine and glutamate metabolism by GlnR and GlnA in Streptococcus pneumoniae. J Biol Chem (2006) 1.50
Autolysis of Lactococcus lactis is increased upon D-alanine depletion of peptidoglycan and lipoteichoic acids. J Bacteriol (2005) 1.49
The novel transcriptional regulator SczA mediates protection against Zn2+ stress by activation of the Zn2+-resistance gene czcD in Streptococcus pneumoniae. Mol Microbiol (2007) 1.49
Redox sensing by a Rex-family repressor is involved in the regulation of anaerobic gene expression in Staphylococcus aureus. Mol Microbiol (2010) 1.49
The Rok protein of Bacillus subtilis represses genes for cell surface and extracellular functions. J Bacteriol (2005) 1.49
A novel class of heat and secretion stress-responsive genes is controlled by the autoregulated CssRS two-component system of Bacillus subtilis. J Bacteriol (2002) 1.48
S-bacillithiolation protects against hypochlorite stress in Bacillus subtilis as revealed by transcriptomics and redox proteomics. Mol Cell Proteomics (2011) 1.48