Published in Annu Rev Biochem on January 01, 2004
Drug resistance in leishmaniasis. Clin Microbiol Rev (2006) 7.35
Small molecule obatoclax (GX15-070) antagonizes MCL-1 and overcomes MCL-1-mediated resistance to apoptosis. Proc Natl Acad Sci U S A (2007) 4.92
Apoptotic and autophagic cell death induced by histone deacetylase inhibitors. Proc Natl Acad Sci U S A (2004) 4.20
Human inhibitor of apoptosis proteins: why XIAP is the black sheep of the family. EMBO Rep (2006) 4.15
Role of thioredoxin in the response of normal and transformed cells to histone deacetylase inhibitors. Proc Natl Acad Sci U S A (2005) 3.20
MicroRNA: Biogenesis, Function and Role in Cancer. Curr Genomics (2010) 2.80
Inhibiting the mitochondrial fission machinery does not prevent Bax/Bak-dependent apoptosis. Mol Cell Biol (2006) 2.71
Sexually dimorphic neurons in the ventromedial hypothalamus govern mating in both sexes and aggression in males. Cell (2013) 2.41
Bistability in apoptosis: roles of bax, bcl-2, and mitochondrial permeability transition pores. Biophys J (2005) 2.09
Translational control of cytochrome c by RNA-binding proteins TIA-1 and HuR. Mol Cell Biol (2006) 2.05
A three-helix homo-oligomerization domain containing BH3 and BH1 is responsible for the apoptotic activity of Bax. Genes Dev (2007) 1.97
A ubiquitin ligase complex regulates caspase activation during sperm differentiation in Drosophila. PLoS Biol (2007) 1.96
Histone Arg modifications and p53 regulate the expression of OKL38, a mediator of apoptosis. J Biol Chem (2008) 1.93
NALP inflammasomes: a central role in innate immunity. Semin Immunopathol (2007) 1.91
Apoptosis regulation in tetraploid cancer cells. EMBO J (2006) 1.89
The clinical development of histone deacetylase inhibitors as targeted anticancer drugs. Expert Opin Investig Drugs (2010) 1.79
Transient binding of an activator BH3 domain to the Bak BH3-binding groove initiates Bak oligomerization. J Cell Biol (2011) 1.73
Apoptotic caspases prevent the induction of type I interferons by mitochondrial DNA. Cell (2014) 1.70
Intrinsic apoptotic and thioredoxin pathways in human prostate cancer cell response to histone deacetylase inhibitor. Proc Natl Acad Sci U S A (2006) 1.67
Mitochondrial p32 is a critical mediator of ARF-induced apoptosis. Cancer Cell (2008) 1.66
Many players in BCL-2 family affairs. Trends Biochem Sci (2014) 1.64
Inhibitors of protein disulfide isomerase suppress apoptosis induced by misfolded proteins. Nat Chem Biol (2010) 1.62
Kaposi's sarcoma herpesvirus microRNAs induce metabolic transformation of infected cells. PLoS Pathog (2014) 1.61
Impact of local versus global ligand density on cellular adhesion. Nano Lett (2011) 1.58
Tetracyclines: a pleitropic family of compounds with promising therapeutic properties. Review of the literature. Am J Physiol Cell Physiol (2010) 1.56
Drug resistance in leishmaniasis. J Glob Infect Dis (2010) 1.52
Uncoupling protein 2 impacts endothelial phenotype via p53-mediated control of mitochondrial dynamics. Circ Res (2013) 1.48
MondoA-Mlx heterodimers are candidate sensors of cellular energy status: mitochondrial localization and direct regulation of glycolysis. Mol Cell Biol (2006) 1.48
BH3 mimetic obatoclax enhances TRAIL-mediated apoptosis in human pancreatic cancer cells. Clin Cancer Res (2009) 1.45
BID-induced structural changes in BAK promote apoptosis. Nat Struct Mol Biol (2013) 1.45
Mitaplatin, a potent fusion of cisplatin and the orphan drug dichloroacetate. Proc Natl Acad Sci U S A (2009) 1.43
A peptide inhibitor of cytochrome c/inositol 1,4,5-trisphosphate receptor binding blocks intrinsic and extrinsic cell death pathways. Proc Natl Acad Sci U S A (2005) 1.42
The two Drosophila cytochrome C proteins can function in both respiration and caspase activation. EMBO J (2005) 1.42
The BH3 alpha-helical mimic BH3-M6 disrupts Bcl-X(L), Bcl-2, and MCL-1 protein-protein interactions with Bax, Bak, Bad, or Bim and induces apoptosis in a Bax- and Bim-dependent manner. J Biol Chem (2010) 1.39
Cytochrome c biogenesis: the Ccm system. Trends Microbiol (2010) 1.38
Requirement of biphasic calcium release from the endoplasmic reticulum for Fas-mediated apoptosis. J Cell Biol (2006) 1.36
Conformational changes in BAK, a pore-forming proapoptotic Bcl-2 family member, upon membrane insertion and direct evidence for the existence of BH3-BH3 contact interface in BAK homo-oligomers. J Biol Chem (2010) 1.36
Histone deacetylase inhibitors: a chemical genetics approach to understanding cellular functions. Biochim Biophys Acta (2010) 1.35
Calcium-independent phospholipase A2 localizes in and protects mitochondria during apoptotic induction by staurosporine. J Biol Chem (2006) 1.34
Expression of Huntington's disease protein results in apoptotic neurons in the brains of cloned transgenic pigs. Hum Mol Genet (2010) 1.33
Cytosolic activation of cathepsins mediates parvovirus H-1-induced killing of cisplatin and TRAIL-resistant glioma cells. J Virol (2007) 1.33
Mutations of the mitochondrial holocytochrome c-type synthase in X-linked dominant microphthalmia with linear skin defects syndrome. Am J Hum Genet (2006) 1.32
Perturbation of the Bcl-2 network and an induced Noxa/Bcl-xL interaction trigger mitochondrial dysfunction after DNA damage. J Biol Chem (2010) 1.32
Cytochrome c-d regulates developmental apoptosis in the Drosophila retina. EMBO Rep (2006) 1.26
Isoflurane preconditioning increases B-cell lymphoma-2 expression and reduces cytochrome c release from the mitochondria in the ischemic penumbra of rat brain. Eur J Pharmacol (2008) 1.25
Mitochondrial dysfunction and β-cell failure in type 2 diabetes mellitus. Exp Diabetes Res (2011) 1.25
Noxa/Bcl-2 protein interactions contribute to bortezomib resistance in human lymphoid cells. J Biol Chem (2011) 1.24
SOD2 protects against oxidation-induced apoptosis in mouse retinal pigment epithelium: implications for age-related macular degeneration. Invest Ophthalmol Vis Sci (2005) 1.22
Bcl-2 proteins regulate ER membrane permeability to luminal proteins during ER stress-induced apoptosis. Cell Death Differ (2010) 1.22
c-FLIP knockdown induces ligand-independent DR5-, FADD-, caspase-8-, and caspase-9-dependent apoptosis in breast cancer cells. Biochem Pharmacol (2008) 1.22
Brucella melitensis triggers time-dependent modulation of apoptosis and down-regulation of mitochondrion-associated gene expression in mouse macrophages. Infect Immun (2006) 1.20
Thioredoxin h5 is required for victorin sensitivity mediated by a CC-NBS-LRR gene in Arabidopsis. Plant Cell (2007) 1.20
Mitochondria-mediated apoptosis in mammals. Protein Cell (2014) 1.19
First-in-class cardiolipin-protective compound as a therapeutic agent to restore mitochondrial bioenergetics. Br J Pharmacol (2014) 1.16
Resveratrol induces p53-independent, X-linked inhibitor of apoptosis protein (XIAP)-mediated Bax protein oligomerization on mitochondria to initiate cytochrome c release and caspase activation. J Biol Chem (2011) 1.14
Metalloproteins containing cytochrome, iron-sulfur, or copper redox centers. Chem Rev (2014) 1.13
Small-molecule activation of the TRAIL receptor DR5 in human cancer cells. Nat Chem Biol (2012) 1.13
Role of p53, PUMA, and Bax in wogonin-induced apoptosis in human cancer cells. Biochem Pharmacol (2008) 1.13
The σ2 receptor: a novel protein for the imaging and treatment of cancer. J Med Chem (2013) 1.13
Posttranslational myristoylation of caspase-activated p21-activated protein kinase 2 (PAK2) potentiates late apoptotic events. Proc Natl Acad Sci U S A (2006) 1.13
Apoptosome-independent activation of the lysosomal cell death pathway by caspase-9. Mol Cell Biol (2006) 1.12
Context-dependent Bcl-2/Bak interactions regulate lymphoid cell apoptosis. J Biol Chem (2009) 1.12
Regulator of calcineurin 1 (RCAN1) facilitates neuronal apoptosis through caspase-3 activation. J Biol Chem (2011) 1.11
Identification of a novel protein MICS1 that is involved in maintenance of mitochondrial morphology and apoptotic release of cytochrome c. Mol Biol Cell (2008) 1.10
Bax contains two functional mitochondrial targeting sequences and translocates to mitochondria in a conformational change- and homo-oligomerization-driven process. J Biol Chem (2009) 1.10
Low-dose valproic acid enhances radiosensitivity of prostate cancer through acetylated p53-dependent modulation of mitochondrial membrane potential and apoptosis. Mol Cancer Res (2011) 1.10
Characterization of age-dependent and progressive cortical neuronal degeneration in presenilin conditional mutant mice. PLoS One (2010) 1.10
The female gametophyte. Arabidopsis Book (2011) 1.09
Mitochondrial shuttling of CAP1 promotes actin- and cofilin-dependent apoptosis. J Cell Sci (2008) 1.09
The cancer cell's "power plants" as promising therapeutic targets: an overview. J Bioenerg Biomembr (2007) 1.09
The power and the promise of restimulation-induced cell death in human immune diseases. Immunol Rev (2010) 1.09
Limited role for the bilirubin-biliverdin redox amplification cycle in the cellular antioxidant protection by biliverdin reductase. J Biol Chem (2009) 1.08
Interactions between SIRT1 and AP-1 reveal a mechanistic insight into the growth promoting properties of alumina (Al2O3) nanoparticles in mouse skin epithelial cells. Carcinogenesis (2008) 1.08
Construction and analysis of a modular model of caspase activation in apoptosis. Theor Biol Med Model (2008) 1.08
A dimeric Smac/diablo peptide directly relieves caspase-3 inhibition by XIAP. Dynamic and cooperative regulation of XIAP by Smac/Diablo. J Biol Chem (2007) 1.07
Cationic gradient reversal and cytoskeleton-independent volume regulatory pathways define an early stage of apoptosis. J Biol Chem (2008) 1.07
Voltage dependent anion channels (VDACs): a brief introduction with a focus on the outer mitochondrial compartment's roles together with hexokinase-2 in the "Warburg effect" in cancer. J Bioenerg Biomembr (2008) 1.07
Inhibition of CED-3 zymogen activation and apoptosis in Caenorhabditis elegans by caspase homolog CSP-3. Nat Struct Mol Biol (2008) 1.06
PHAPI/pp32 suppresses tumorigenesis by stimulating apoptosis. J Biol Chem (2009) 1.05
Emerging understanding of Bcl-2 biology: Implications for neoplastic progression and treatment. Biochim Biophys Acta (2015) 1.05
Apoptosis in murine norovirus-infected RAW264.7 cells is associated with downregulation of survivin. J Virol (2009) 1.04
Myosin VI is a mediator of the p53-dependent cell survival pathway. Mol Cell Biol (2006) 1.04
Role of apoptosis-inducing factor, proline dehydrogenase, and NADPH oxidase in apoptosis and oxidative stress. Cell Health Cytoskelet (2012) 1.04
Deletion of Cryptococcus neoformans AIF ortholog promotes chromosome aneuploidy and fluconazole-resistance in a metacaspase-independent manner. PLoS Pathog (2011) 1.03
Minnelide: a novel therapeutic that promotes apoptosis in non-small cell lung carcinoma in vivo. PLoS One (2013) 1.02
Oxidative phosphorylation dysfunction modulates expression of extracellular matrix--remodeling genes and invasion. Carcinogenesis (2005) 1.01
Induction of antioxidant and detoxification response by oxidants in cardiomyocytes: evidence from gene expression profiling and activation of Nrf2 transcription factor. J Mol Cell Cardiol (2006) 1.01
Histone deacetylase inhibitors and cell death. Cell Mol Life Sci (2014) 1.00
Brugia malayi gene expression in response to the targeting of the Wolbachia endosymbiont by tetracycline treatment. PLoS Negl Trop Dis (2009) 1.00
Regulation of the oxidative stress response through Slt2p-dependent destruction of cyclin C in Saccharomyces cerevisiae. Genetics (2005) 1.00
Resveratrol inhibits uveal melanoma tumor growth via early mitochondrial dysfunction. Invest Ophthalmol Vis Sci (2008) 0.99
Inactivation of prosurvival Bcl-2 proteins activates Bax/Bak through the outer mitochondrial membrane. Genes Dev (2016) 0.98
Involvement of Exo1b in DNA damage-induced apoptosis. Nucleic Acids Res (2009) 0.98
Genome-wide siRNA screen reveals coupling between mitotic apoptosis and adaptation. EMBO J (2014) 0.98
Mitochondrial morphogenesis, dendrite development, and synapse formation in cerebellum require both Bcl-w and the glutamate receptor delta2. PLoS Genet (2008) 0.98
Mitochondrion-associated protein LRPPRC suppresses the initiation of basal levels of autophagy via enhancing Bcl-2 stability. Biochem J (2013) 0.97
Role of cytochrome C in apoptosis: increased sensitivity to tumor necrosis factor alpha is associated with respiratory defects but not with lack of cytochrome C release. Mol Cell Biol (2007) 0.97
Leptospira interrogans induces apoptosis in macrophages via caspase-8- and caspase-3-dependent pathways. Infect Immun (2008) 0.97
PP2A:B56{epsilon}, a substrate of caspase-3, regulates p53-dependent and p53-independent apoptosis during development. J Biol Chem (2010) 0.96
Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha. Cell (2009) 11.36
R2D2, a bridge between the initiation and effector steps of the Drosophila RNAi pathway. Science (2003) 9.53
The BioGRID Interaction Database: 2011 update. Nucleic Acids Res (2010) 8.46
Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis. Cell (2005) 6.86
TNF-alpha induces two distinct caspase-8 activation pathways. Cell (2008) 6.81
Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase. Cell (2012) 6.56
Argonaute2 cleaves the anti-guide strand of siRNA during RISC activation. Cell (2005) 6.47
Elimination of Mcl-1 is required for the initiation of apoptosis following ultraviolet irradiation. Genes Dev (2003) 6.17
Specific ablation of the apoptotic functions of cytochrome C reveals a differential requirement for cytochrome C and Apaf-1 in apoptosis. Cell (2005) 5.37
WormBase: a comprehensive resource for nematode research. Nucleic Acids Res (2009) 5.20
Autocrine TNFalpha signaling renders human cancer cells susceptible to Smac-mimetic-induced apoptosis. Cancer Cell (2007) 5.09
Jaundice Constrain or Indication? Response. Radiology (2017) 5.07
A small molecule Smac mimic potentiates TRAIL- and TNFalpha-mediated cell death. Science (2004) 4.95
The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways. Cell (2012) 4.37
WormBase: new content and better access. Nucleic Acids Res (2006) 4.01
WormBase 2012: more genomes, more data, new website. Nucleic Acids Res (2011) 3.87
WormBase 2007. Nucleic Acids Res (2007) 3.69
Biochemical identification of Argonaute 2 as the sole protein required for RNA-induced silencing complex activity. Proc Natl Acad Sci U S A (2004) 3.63
Distinctive roles of PHAP proteins and prothymosin-alpha in a death regulatory pathway. Science (2003) 3.59
Degradation of Mcl-1 by beta-TrCP mediates glycogen synthase kinase 3-induced tumor suppression and chemosensitization. Mol Cell Biol (2007) 3.23
Three-dimensional structure of the apoptosome: implications for assembly, procaspase-9 binding, and activation. Mol Cell (2002) 3.06
The ER UDPase ENTPD5 promotes protein N-glycosylation, the Warburg effect, and proliferation in the PTEN pathway. Cell (2010) 2.97
Indirect emissions from biofuels: how important? Science (2009) 2.71
Toll-like receptors activate programmed necrosis in macrophages through a receptor-interacting kinase-3-mediated pathway. Proc Natl Acad Sci U S A (2011) 2.64
Dietary flavonoids: effects on xenobiotic and carcinogen metabolism. Toxicol In Vitro (2005) 2.60
WormBase 2014: new views of curated biology. Nucleic Acids Res (2013) 2.39
The role of oxygen during fracture healing. Bone (2012) 2.21
Formation of apoptosome is initiated by cytochrome c-induced dATP hydrolysis and subsequent nucleotide exchange on Apaf-1. Proc Natl Acad Sci U S A (2005) 2.18
Nutrient starvation elicits an acute autophagic response mediated by Ulk1 dephosphorylation and its subsequent dissociation from AMPK. Proc Natl Acad Sci U S A (2011) 2.06
Cytochrome P450 2E1 contributes to ethanol-induced fatty liver in mice. Hepatology (2008) 1.90
HIV/STD prevalence among men who have sex with men in Chengdu, China and associated risk factors for HIV infection. J Acquir Immune Defic Syndr (2010) 1.76
Cytokines in alcoholic liver disease. Arch Toxicol (2012) 1.74
Silica encapsulation of n-octadecane via sol-gel process: a novel microencapsulated phase-change material with enhanced thermal conductivity and performance. J Colloid Interface Sci (2009) 1.67
Generation and characterization of Smac/DIABLO-deficient mice. Mol Cell Biol (2002) 1.61
A Bayesian connectivity-based approach to constructing probabilistic gene regulatory networks. Bioinformatics (2004) 1.57
A structure of the human apoptosome at 12.8 A resolution provides insights into this cell death platform. Structure (2005) 1.53
Autophagy occurs upstream or parallel to the apoptosome during histolytic cell death. Development (2006) 1.50
Chronic alcohol-induced liver injury and oxidant stress are decreased in cytochrome P4502E1 knockout mice and restored in humanized cytochrome P4502E1 knock-in mice. Free Radic Biol Med (2010) 1.47
PHAPI, CAS, and Hsp70 promote apoptosome formation by preventing Apaf-1 aggregation and enhancing nucleotide exchange on Apaf-1. Mol Cell (2008) 1.44
Three-dimensional structure of a double apoptosome formed by the Drosophila Apaf-1 related killer. J Mol Biol (2005) 1.43
Overcoming cancer cell resistance to Smac mimetic induced apoptosis by modulating cIAP-2 expression. Proc Natl Acad Sci U S A (2010) 1.42
Structure of an apoptosome-procaspase-9 CARD complex. Structure (2010) 1.42
Interaction with Tap42 is required for the essential function of Sit4 and type 2A phosphatases. Mol Biol Cell (2003) 1.41
Osteopontin, an oxidant stress sensitive cytokine, up-regulates collagen-I via integrin α(V)β(3) engagement and PI3K/pAkt/NFκB signaling. Hepatology (2012) 1.40
The difference in superior adjacent segment pathology after lumbar posterolateral fusion by using 2 different pedicle screw insertion techniques in 9-year minimum follow-up. Spine (Phila Pa 1976) (2014) 1.40
MERTK receptor tyrosine kinase is a therapeutic target in melanoma. J Clin Invest (2013) 1.34
Gene clustering based on clusterwide mutual information. J Comput Biol (2004) 1.30
Gene regulatory network reconstruction using conditional mutual information. EURASIP J Bioinform Syst Biol (2008) 1.30
Missing-value estimation using linear and non-linear regression with Bayesian gene selection. Bioinformatics (2003) 1.27
Automatic categorization of diverse experimental information in the bioscience literature. BMC Bioinformatics (2012) 1.27
Multiple roles for CCR2 during fracture healing. Dis Model Mech (2010) 1.26
Discovery of Novel Small Molecule Mer Kinase Inhibitors for the Treatment of Pediatric Acute Lymphoblastic Leukemia. ACS Med Chem Lett (2012) 1.22
Biochemical mechanisms of the RNA-induced silencing complex. Cell Res (2007) 1.22
Control of vesicle fusion by a tyrosine phosphatase. Nat Cell Biol (2004) 1.21
Wnt/beta-Catenin pathway in human glioma: expression pattern and clinical/prognostic correlations. Clin Exp Med (2010) 1.19
Diazonamide toxins reveal an unexpected function for ornithine delta-amino transferase in mitotic cell division. Proc Natl Acad Sci U S A (2007) 1.19
Quantitative modeling of coupled piezo-elastodynamic behavior of piezoelectric actuators bonded to an elastic medium for structural health monitoring: a review. Sensors (Basel) (2010) 1.18
Mitochondrial activation of apoptosis. Cell (2004) 1.17
Customized multiwavelets for planetary gearbox fault detection based on vibration sensor signals. Sensors (Basel) (2013) 1.15
Binarization of microarray data on the basis of a mixture model. Mol Cancer Ther (2003) 1.15
Small-molecule activation of the TRAIL receptor DR5 in human cancer cells. Nat Chem Biol (2012) 1.13
AMPK and mTOR coordinate the regulation of Ulk1 and mammalian autophagy initiation. Autophagy (2011) 1.13
SMAC mimetic (JP1201) sensitizes non-small cell lung cancers to multiple chemotherapy agents in an IAP-dependent but TNF-α-independent manner. Cancer Res (2011) 1.13
CYP2E1 enhances ethanol-induced lipid accumulation but impairs autophagy in HepG2 E47 cells. Biochem Biophys Res Commun (2010) 1.12
Therapeutic anticancer efficacy of a synthetic diazonamide analog in the absence of overt toxicity. Proc Natl Acad Sci U S A (2007) 1.12
Transcriptome analysis of leaf tissue of Raphanus sativus by RNA sequencing. PLoS One (2013) 1.11
Lipopolysaccharide-induced liver injury in rats treated with the CYP2E1 inducer pyrazole. Am J Physiol Gastrointest Liver Physiol (2005) 1.11
Combinatorial photothermal and immuno cancer therapy using chitosan-coated hollow copper sulfide nanoparticles. ACS Nano (2014) 1.10
Amplitude of low-frequency oscillations in first-episode, treatment-naive patients with major depressive disorder: a resting-state functional MRI study. PLoS One (2012) 1.09
Remarkable performance of Ir1/FeO(x) single-atom catalyst in water gas shift reaction. J Am Chem Soc (2013) 1.09
Effects of rare earth elements on the growth of Cistanche deserticola cells and the production of phenylethanoid glycosides. J Biotechnol (2003) 1.09
Peli1 promotes microglia-mediated CNS inflammation by regulating Traf3 degradation. Nat Med (2013) 1.08
The interaction of Schwann cells with chitosan membranes and fibers in vitro. Biomaterials (2004) 1.07
Exogenous smac induces competence and permits caspase activation in sympathetic neurons. J Neurosci (2002) 1.07
Identification of gene interactions associated with disease from gene expression data using synergy networks. BMC Syst Biol (2008) 1.04
UNC1062, a new and potent Mer inhibitor. Eur J Med Chem (2013) 1.03
Effects of L-lactate and D-mannitol on gamma-hydroxybutyrate toxicokinetics and toxicodynamics in rats. Drug Metab Dispos (2008) 1.03
Endonuclease G is required for early embryogenesis and normal apoptosis in mice. Proc Natl Acad Sci U S A (2003) 1.02
The E3 ubiquitin ligase Mule acts through the ATM-p53 axis to maintain B lymphocyte homeostasis. J Exp Med (2012) 1.02
Umbilical cord mesenchymal stem cell transplantation significantly improves neurological function in patients with sequelae of traumatic brain injury. Brain Res (2013) 1.01
Sparse reconstruction for quantitative bioluminescence tomography based on the incomplete variables truncated conjugate gradient method. Opt Express (2010) 1.01
STAT3, a Poor Survival Predicator, Is Associated with Lymph Node Metastasis from Breast Cancer. J Breast Cancer (2013) 1.00
Origins of the high 14-helix propensity of cyclohexyl-rigidified residues in beta-peptides. Org Lett (2007) 1.00
A new fossil silky lacewing genus (Neuroptera, Psychopsidae) from the Early Cretaceous Yixian Formation of China. Zookeys (2011) 1.00
Analysis of aqueous glue coating proteins on the silk fibers of the cob weaver, Latrodectus hesperus. Biochemistry (2007) 1.00
Alcohol steatosis and cytotoxicity: the role of cytochrome P4502E1 and autophagy. Free Radic Biol Med (2012) 0.99
UNC2025, a potent and orally bioavailable MER/FLT3 dual inhibitor. J Med Chem (2014) 0.99
Pseudo-cyclization through intramolecular hydrogen bond enables discovery of pyridine substituted pyrimidines as new Mer kinase inhibitors. J Med Chem (2013) 0.96
A new kind of cell suicide: mechanisms and functions of programmed necrosis. Trends Biochem Sci (2014) 0.96
Inference of gene regulatory networks from genome-wide knockout fitness data. Bioinformatics (2012) 0.95
CYP2E1 Sensitizes the Liver to LPS- and TNF α-Induced Toxicity via Elevated Oxidative and Nitrosative Stress and Activation of ASK-1 and JNK Mitogen-Activated Kinases. Int J Hepatol (2011) 0.95
Human IgG Fc-glycosylation profiling reveals associations with age, sex, female sex hormones and thyroid cancer. J Proteomics (2012) 0.95
Development of a high-throughput assay for identifying inhibitors of TBK1 and IKKε. PLoS One (2012) 0.95
Mechanical stability affects angiogenesis during early fracture healing. J Orthop Trauma (2011) 0.94
Cytochrome P4502E1, oxidative stress, JNK, and autophagy in acute alcohol-induced fatty liver. Free Radic Biol Med (2012) 0.94
A preliminary evaluation of efficacy and safety of Wharton's jelly mesenchymal stem cell transplantation in patients with type 2 diabetes mellitus. Stem Cell Res Ther (2014) 0.93
Optimization of ultrasonic circulating extraction of polysaccharides from Asparagus officinalis using response surface methodology. Int J Biol Macromol (2011) 0.93
Tumor microRNA-335 expression is associated with poor prognosis in human glioma. Med Oncol (2012) 0.93
The Efficiency of Zero-profile Implant in Anterior Cervical Discectomy Fusion: A Prospective Controlled Long-term Follow-up Study. J Spinal Disord Tech (2015) 0.93
Human heat shock protein 105/110 kDa (Hsp105/110) regulates biogenesis and quality control of misfolded cystic fibrosis transmembrane conductance regulator at multiple levels. J Biol Chem (2012) 0.92