Published in Am J Cardiol on June 15, 2004
Dallas Heart Study 2: Return Clinic Visit for the Dallas Heart Study Cohort | NCT00344903
A common allele on chromosome 9 associated with coronary heart disease. Science (2007) 20.37
Population-based resequencing of ANGPTL4 uncovers variations that reduce triglycerides and increase HDL. Nat Genet (2007) 13.78
Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease. Nat Genet (2008) 10.87
HDL cholesterol efflux capacity and incident cardiovascular events. N Engl J Med (2014) 8.61
Multiple rare variants in NPC1L1 associated with reduced sterol absorption and plasma low-density lipoprotein levels. Proc Natl Acad Sci U S A (2006) 8.20
A spectrum of PCSK9 alleles contributes to plasma levels of low-density lipoprotein cholesterol. Am J Hum Genet (2006) 7.89
Association of troponin T detected with a highly sensitive assay and cardiac structure and mortality risk in the general population. JAMA (2010) 6.11
Rare loss-of-function mutations in ANGPTL family members contribute to plasma triglyceride levels in humans. J Clin Invest (2008) 5.05
Optimal tests for rare variant effects in sequencing association studies. Biostatistics (2012) 4.69
Common missense variant in the glucokinase regulatory protein gene is associated with increased plasma triglyceride and C-reactive protein but lower fasting glucose concentrations. Diabetes (2008) 4.20
Dysfunctional adiposity and the risk of prediabetes and type 2 diabetes in obese adults. JAMA (2012) 4.04
A novel adaptive method for the analysis of next-generation sequencing data to detect complex trait associations with rare variants due to gene main effects and interactions. PLoS Genet (2010) 3.78
Molecular characterization of loss-of-function mutations in PCSK9 and identification of a compound heterozygote. Am J Hum Genet (2006) 3.38
Ethnic differences in hepatic steatosis: an insulin resistance paradox? Hepatology (2009) 3.08
Population-based risk assessment of APOL1 on renal disease. J Am Soc Nephrol (2011) 2.81
Effectiveness of a barber-based intervention for improving hypertension control in black men: the BARBER-1 study: a cluster randomized trial. Arch Intern Med (2010) 2.78
Atypical angiopoietin-like protein that regulates ANGPTL3. Proc Natl Acad Sci U S A (2012) 2.62
Genetic defects in surfactant protein A2 are associated with pulmonary fibrosis and lung cancer. Am J Hum Genet (2008) 2.53
Exome-wide association study identifies a TM6SF2 variant that confers susceptibility to nonalcoholic fatty liver disease. Nat Genet (2014) 2.49
Common single-nucleotide polymorphisms act in concert to affect plasma levels of high-density lipoprotein cholesterol. Am J Hum Genet (2007) 2.28
Age- and sex-dependent upper reference limits for the high-sensitivity cardiac troponin T assay. J Am Coll Cardiol (2014) 2.22
Dissociation between APOC3 variants, hepatic triglyceride content and insulin resistance. Hepatology (2010) 2.09
Genetic and metabolic determinants of plasma PCSK9 levels. J Clin Endocrinol Metab (2009) 1.95
10-Year Coronary Heart Disease Risk Prediction Using Coronary Artery Calcium and Traditional Risk Factors: Derivation in the MESA (Multi-Ethnic Study of Atherosclerosis) With Validation in the HNR (Heinz Nixdorf Recall) Study and the DHS (Dallas Heart Study). J Am Coll Cardiol (2015) 1.92
An evolutionary framework for association testing in resequencing studies. PLoS Genet (2010) 1.74
Left atrial structure and function and clinical outcomes in the general population. Eur Heart J (2012) 1.64
Target Organ Complications and Cardiovascular Events Associated With Masked Hypertension and White-Coat Hypertension: Analysis From the Dallas Heart Study. J Am Coll Cardiol (2015) 1.62
Higher natriuretic peptide levels associate with a favorable adipose tissue distribution profile. J Am Coll Cardiol (2013) 1.58
The genetics of NAFLD. Nat Rev Gastroenterol Hepatol (2013) 1.55
Genetics: a gene of rare effect. Nature (2013) 1.54
Associations of visceral and abdominal subcutaneous adipose tissue with markers of cardiac and metabolic risk in obese adults. Obesity (Silver Spring) (2013) 1.53
Replication strategies for rare variant complex trait association studies via next-generation sequencing. Am J Hum Genet (2010) 1.51
Sex differences in the relationship between C-reactive protein and body fat. J Clin Endocrinol Metab (2009) 1.49
A classical likelihood based approach for admixture mapping using EM algorithm. Hum Genet (2006) 1.43
Association of a 4-Tiered Classification of LV Hypertrophy With Adverse CV Outcomes in the General Population. JACC Cardiovasc Imaging (2015) 1.41
An international comparative study of blood pressure in populations of European vs. African descent. BMC Med (2005) 1.38
Functional characterization of genetic variants in NPC1L1 supports the sequencing extremes strategy to identify complex trait genes. Hum Mol Genet (2008) 1.37
Insulin resistance and risk factors for cardiovascular disease in young adult survivors of childhood acute lymphoblastic leukemia. J Clin Oncol (2009) 1.36
Detecting rare variant effects using extreme phenotype sampling in sequencing association studies. Genet Epidemiol (2012) 1.35
Adipose tissue mass and location affect circulating adiponectin levels. Diabetologia (2011) 1.32
Admixture mapping provides evidence of association of the VNN1 gene with hypertension. PLoS One (2007) 1.31
Obesity and dyslipidemia in South Asians. Nutrients (2013) 1.31
Association between circulating soluble receptor for advanced glycation end products and atherosclerosis: observations from the Dallas Heart Study. Diabetes Care (2009) 1.30
A unified mixed-effects model for rare-variant association in sequencing studies. Genet Epidemiol (2013) 1.29
Biomarkers of chronic cardiac injury and hemodynamic stress identify a malignant phenotype of left ventricular hypertrophy in the general population. J Am Coll Cardiol (2012) 1.25
Influence of race and sex on lipoprotein-associated phospholipase A2 levels: observations from the Dallas Heart Study. Atherosclerosis (2007) 1.25
A permutation procedure to correct for confounders in case-control studies, including tests of rare variation. Am J Hum Genet (2012) 1.25
Body size misperception: a novel determinant in the obesity epidemic. Arch Intern Med (2010) 1.18
Relationship of oxidized phospholipids on apolipoprotein B-100 particles to race/ethnicity, apolipoprotein(a) isoform size, and cardiovascular risk factors: results from the Dallas Heart Study. Circulation (2009) 1.16
Metabolic disturbances associated with systemic lupus erythematosus. PLoS One (2012) 1.15
Physical activity participation, health perceptions, and cardiovascular disease mortality in a multiethnic population: the Dallas Heart Study. Am Heart J (2012) 1.14
Association of growth differentiation factor-15 with coronary atherosclerosis and mortality in a young, multiethnic population: observations from the Dallas Heart Study. Clin Chem (2011) 1.14
Cardiovascular outcome associations among cardiovascular magnetic resonance measures of arterial stiffness: the Dallas heart study. J Cardiovasc Magn Reson (2014) 1.12
Atherosclerotic cardiovascular disease prevention: a comparison between the third adult treatment panel and the new 2013 Treatment of Blood Cholesterol Guidelines. Circ Cardiovasc Qual Outcomes (2014) 1.12
Estimating genetic effects and quantifying missing heritability explained by identified rare-variant associations. Am J Hum Genet (2012) 1.07
The Measurement to Understand Reclassification of Disease of Cabarrus/Kannapolis (MURDOCK) Study Community Registry and Biorepository. Am J Transl Res (2012) 1.07
Frequency of the cholesteryl ester storage disease common LIPA E8SJM mutation (c.894G>A) in various racial and ethnic groups. Hepatology (2013) 1.06
Association of urinary sodium/potassium ratio with blood pressure: sex and racial differences. Clin J Am Soc Nephrol (2011) 1.06
A barber-based intervention for hypertension in African American men: design of a group randomized trial. Am Heart J (2009) 1.05
Multiple independent genetic factors at NOS1AP modulate the QT interval in a multi-ethnic population. PLoS One (2009) 1.05
Relation of regional fat distribution to left ventricular structure and function. Circ Cardiovasc Imaging (2013) 1.04
Reversible sympathetic overactivity in hypertensive patients with primary aldosteronism. J Clin Endocrinol Metab (2010) 1.04
Effect of ageing on left ventricular compliance and distensibility in healthy sedentary humans. J Physiol (2012) 1.02
White matter hyperintensities: use of aortic arch pulse wave velocity to predict volume independent of other cardiovascular risk factors. Radiology (2013) 1.01
Variable contributions of fat content and distribution to metabolic syndrome risk factors. Metab Syndr Relat Disord (2008) 0.99
The Swedish CArdioPulmonary BioImage Study: objectives and design. J Intern Med (2015) 0.98
The MBOAT7-TMC4 Variant rs641738 Increases Risk of Nonalcoholic Fatty Liver Disease in Individuals of European Descent. Gastroenterology (2016) 0.98
Pancreatic steatosis and its relationship to β-cell dysfunction in humans: racial and ethnic variations. Diabetes Care (2012) 0.97
Interactions between smoking, pulmonary surfactant protein B, and atherosclerosis in the general population: the Dallas Heart Study. Arterioscler Thromb Vasc Biol (2011) 0.97
Normocalcemic hyperparathyroidism and hypoparathyroidism in two community-based nonreferral populations. J Clin Endocrinol Metab (2013) 0.94
Single-nucleotide polymorphisms in LPA explain most of the ancestry-specific variation in Lp(a) levels in African Americans. PLoS One (2011) 0.94
DNA polymerase-α regulates the activation of type I interferons through cytosolic RNA:DNA synthesis. Nat Immunol (2016) 0.93
Neighborhood-level socioeconomic deprivation predicts weight gain in a multi-ethnic population: longitudinal data from the Dallas Heart Study. Prev Med (2014) 0.93
Race-specific associations of myeloperoxidase with atherosclerosis in a population-based sample: the Dallas Heart Study. Atherosclerosis (2011) 0.93
The Florey Adelaide Male Ageing Study (FAMAS): design, procedures & participants. BMC Public Health (2007) 0.92
The counseling African Americans to Control Hypertension (CAATCH) Trial: baseline demographic, clinical, psychosocial, and behavioral characteristics. Implement Sci (2011) 0.92
Differential associations between soluble cellular adhesion molecules and atherosclerosis in the Dallas Heart Study: a distinct role for soluble endothelial cell-selective adhesion molecule. Arterioscler Thromb Vasc Biol (2009) 0.91
Rare variant association testing by adaptive combination of P-values. PLoS One (2014) 0.90
Impaired left ventricular stroke volume reserve during clinical dobutamine stress predicts future episodes of pulmonary edema. J Am Coll Cardiol (2011) 0.90
Cardiovascular lifetime risk predicts incidence of coronary calcification in individuals with low short-term risk: the Dallas Heart Study. J Am Heart Assoc (2014) 0.90
Relationship between perceptions about neighborhood environment and prevalent obesity: data from the Dallas Heart Study. Obesity (Silver Spring) (2013) 0.90
Genetic, anatomic, and clinical determinants of human serum sterol and vitamin D levels. Proc Natl Acad Sci U S A (2014) 0.90
A weighted false discovery rate control procedure reveals alleles at FOXA2 that influence fasting glucose levels. Am J Hum Genet (2010) 0.89
Chemical modulation of glycerolipid signaling and metabolic pathways. Biochim Biophys Acta (2014) 0.89
Increased prevalence of concentric left ventricular hypertrophy in African-Americans: will an epidemic of heart failure follow? Heart Fail Rev (2006) 0.88
Waist circumference as measure of abdominal fat compartments. J Obes (2013) 0.88
Plasma Levels of Risk-Variant APOL1 Do Not Associate with Renal Disease in a Population-Based Cohort. J Am Soc Nephrol (2016) 0.87
Measurement of pancreatic volume by abdominal MRI: a validation study. PLoS One (2013) 0.87
Effect of healthy aging on left ventricular relaxation and diastolic suction. Am J Physiol Heart Circ Physiol (2012) 0.87
Addition of highly sensitive troponin T and N-terminal pro-B-type natriuretic peptide to electrocardiography for detection of left ventricular hypertrophy: results from the Dallas Heart Study. Hypertension (2012) 0.86
A unified framework for detecting rare variant quantitative trait associations in pedigree and unrelated individuals via sequence data. Hum Hered (2012) 0.86
Effects of age and aerobic fitness on myocardial lipid content. Circ Cardiovasc Imaging (2013) 0.86
Detecting associations of rare variants with common diseases: collapsing or haplotyping? Brief Bioinform (2015) 0.86
Association testing of clustered rare causal variants in case-control studies. PLoS One (2014) 0.85
Cardiovascular effects of 1 year of alagebrium and endurance exercise training in healthy older individuals. Circ Heart Fail (2013) 0.85
Association of depressive symptoms with hippocampal volume in 1936 adults. Neuropsychopharmacology (2013) 0.85
Change in Neighborhood Socioeconomic Status and Weight Gain: Dallas Heart Study. Am J Prev Med (2015) 0.84
Disparities in counseling for lifestyle modification among obese adults: insights from the Dallas Heart Study. Obesity (Silver Spring) (2011) 0.84
Genetic background in nonalcoholic fatty liver disease: A comprehensive review. World J Gastroenterol (2015) 0.84
Genetic-related and carbohydrate-related factors affecting liver fat accumulation. Curr Opin Clin Nutr Metab Care (2012) 0.84
Sequence variations in PCSK9, low LDL, and protection against coronary heart disease. N Engl J Med (2006) 23.83
Multiple rare alleles contribute to low plasma levels of HDL cholesterol. Science (2004) 21.65
A common allele on chromosome 9 associated with coronary heart disease. Science (2007) 20.37
Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity. Hepatology (2004) 18.86
Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits. PLoS Genet (2007) 14.99
Population-based resequencing of ANGPTL4 uncovers variations that reduce triglycerides and increase HDL. Nat Genet (2007) 13.78
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25
Low LDL cholesterol in individuals of African descent resulting from frequent nonsense mutations in PCSK9. Nat Genet (2005) 12.12
Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease. Nat Genet (2008) 10.87
Hypertension prevalence and blood pressure levels in 6 European countries, Canada, and the United States. JAMA (2003) 9.06
Magnetic resonance spectroscopy to measure hepatic triglyceride content: prevalence of hepatic steatosis in the general population. Am J Physiol Endocrinol Metab (2004) 8.36
Multiple rare variants in NPC1L1 associated with reduced sterol absorption and plasma low-density lipoprotein levels. Proc Natl Acad Sci U S A (2006) 8.20
Subclinical thyroid disease: scientific review and guidelines for diagnosis and management. JAMA (2004) 8.12
Human fatty liver disease: old questions and new insights. Science (2011) 8.03
A spectrum of PCSK9 alleles contributes to plasma levels of low-density lipoprotein cholesterol. Am J Hum Genet (2006) 7.89
Exome sequencing, ANGPTL3 mutations, and familial combined hypolipidemia. N Engl J Med (2010) 6.84
Admixture mapping for hypertension loci with genome-scan markers. Nat Genet (2005) 6.78
Hypertension treatment and control in five European countries, Canada, and the United States. Hypertension (2003) 5.63
Rare loss-of-function mutations in ANGPTL family members contribute to plasma triglyceride levels in humans. J Clin Invest (2008) 5.05
Physical activity does not influence obesity risk: time to clarify the public health message. Int J Epidemiol (2013) 4.71
Monogenic hypercholesterolemia: new insights in pathogenesis and treatment. J Clin Invest (2003) 4.42
Pnpla3I148M knockin mice accumulate PNPLA3 on lipid droplets and develop hepatic steatosis. Hepatology (2014) 4.01
Association mapping, using a mixture model for complex traits. Genet Epidemiol (2002) 3.95
PCSK9: a convertase that coordinates LDL catabolism. J Lipid Res (2008) 3.92
Overexpression of ABCG5 and ABCG8 promotes biliary cholesterol secretion and reduces fractional absorption of dietary cholesterol. J Clin Invest (2002) 3.85
Molecular biology of PCSK9: its role in LDL metabolism. Trends Biochem Sci (2007) 3.59
Human alpha B-crystallin mutation causes oxido-reductive stress and protein aggregation cardiomyopathy in mice. Cell (2007) 3.54
Binding of proprotein convertase subtilisin/kexin type 9 to epidermal growth factor-like repeat A of low density lipoprotein receptor decreases receptor recycling and increases degradation. J Biol Chem (2007) 3.45
A sequence variation (I148M) in PNPLA3 associated with nonalcoholic fatty liver disease disrupts triglyceride hydrolysis. J Biol Chem (2009) 3.41
From the Cover: Whole-genome association study identifies STK39 as a hypertension susceptibility gene. Proc Natl Acad Sci U S A (2008) 3.39
Molecular characterization of loss-of-function mutations in PCSK9 and identification of a compound heterozygote. Am J Hum Genet (2006) 3.38
Disruption of Abcg5 and Abcg8 in mice reveals their crucial role in biliary cholesterol secretion. Proc Natl Acad Sci U S A (2002) 3.09
Left ventricular hypertrophy is more prevalent in blacks than whites in the general population: the Dallas Heart Study. Hypertension (2005) 3.07
A unified association analysis approach for family and unrelated samples correcting for stratification. Am J Hum Genet (2008) 3.00
Disconnect between incidence of nonperforated and perforated appendicitis: implications for pathophysiology and management. Ann Surg (2007) 2.98
Common variants associated with plasma triglycerides and risk for coronary artery disease. Nat Genet (2013) 2.92
Effectiveness of a barber-based intervention for improving hypertension control in black men: the BARBER-1 study: a cluster randomized trial. Arch Intern Med (2010) 2.78
A genome-wide linkage analysis investigating the determinants of blood pressure in whites and African Americans. Am J Hypertens (2003) 2.76
Neighborhood characteristics and hypertension. Epidemiology (2008) 2.70
Atypical angiopoietin-like protein that regulates ANGPTL3. Proc Natl Acad Sci U S A (2012) 2.62
ABCG5 and ABCG8 are obligate heterodimers for protein trafficking and biliary cholesterol excretion. J Biol Chem (2003) 2.48
Impact of body mass and body composition on circulating levels of natriuretic peptides: results from the Dallas Heart Study. Circulation (2005) 2.47
The association of a SNP upstream of INSIG2 with body mass index is reproduced in several but not all cohorts. PLoS Genet (2007) 2.35
Multiple genes for essential-hypertension susceptibility on chromosome 1q. Am J Hum Genet (2006) 2.34
A feed-forward loop amplifies nutritional regulation of PNPLA3. Proc Natl Acad Sci U S A (2010) 2.34
Common single-nucleotide polymorphisms act in concert to affect plasma levels of high-density lipoprotein cholesterol. Am J Hum Genet (2007) 2.28
Linkage analysis of a complex disease through use of admixed populations. Am J Hum Genet (2004) 2.21
Identification by whole-genome resequencing of gene defect responsible for severe hypercholesterolemia. Hum Mol Genet (2010) 2.19
Corin I555(P568) allele is associated with enhanced cardiac hypertrophic response to increased systemic afterload. Hypertension (2007) 2.17
African Americans and Caucasians have a similar prevalence of coronary calcium in the Dallas Heart Study. J Am Coll Cardiol (2004) 2.16
Dissociation between APOC3 variants, hepatic triglyceride content and insulin resistance. Hepatology (2010) 2.09
Midlife fitness and the development of chronic conditions in later life. Arch Intern Med (2012) 2.07
Coexpression of ATP-binding cassette proteins ABCG5 and ABCG8 permits their transport to the apical surface. J Clin Invest (2002) 2.02
A 4-tiered classification of left ventricular hypertrophy based on left ventricular geometry: the Dallas heart study. Circ Cardiovasc Imaging (2010) 2.02
Reverse causation and illness-related weight loss in observational studies of body weight and mortality. Am J Epidemiol (2010) 1.99
Mice lacking ANGPTL8 (Betatrophin) manifest disrupted triglyceride metabolism without impaired glucose homeostasis. Proc Natl Acad Sci U S A (2013) 1.96
WholePathwayScope: a comprehensive pathway-based analysis tool for high-throughput data. BMC Bioinformatics (2006) 1.95
Genetics. The science and business of genetic ancestry testing. Science (2007) 1.95
Genetic and metabolic determinants of plasma PCSK9 levels. J Clin Endocrinol Metab (2009) 1.95
No association between plasma levels of plant sterols and atherosclerosis in mice and men. Arterioscler Thromb Vasc Biol (2004) 1.93
Genome-wide association of anthropometric traits in African- and African-derived populations. Hum Mol Genet (2010) 1.90
ARH is a modular adaptor protein that interacts with the LDL receptor, clathrin, and AP-2. J Biol Chem (2002) 1.89
A combined analysis of genomewide linkage scans for body mass index from the National Heart, Lung, and Blood Institute Family Blood Pressure Program. Am J Hum Genet (2002) 1.87
Impact of energy intake, physical activity, and population-wide weight loss on cardiovascular disease and diabetes mortality in Cuba, 1980-2005. Am J Epidemiol (2007) 1.87
Structural requirements for PCSK9-mediated degradation of the low-density lipoprotein receptor. Proc Natl Acad Sci U S A (2008) 1.86
Corin gene minor allele defined by 2 missense mutations is common in blacks and associated with high blood pressure and hypertension. Circulation (2005) 1.84
Project IMPACT: results from a pilot validity study of a new observational database. Crit Care Med (2002) 1.82
A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry. Nat Genet (2013) 1.82
Cardiac atrophy in women following bed rest. J Appl Physiol (1985) (2007) 1.78
Women have higher left ventricular ejection fractions than men independent of differences in left ventricular volume: the Dallas Heart Study. Circulation (2006) 1.78
Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study. Hum Mol Genet (2011) 1.77
Barbershops as hypertension detection, referral, and follow-up centers for black men. Hypertension (2007) 1.74
Sterol intermediates from cholesterol biosynthetic pathway as liver X receptor ligands. J Biol Chem (2006) 1.72
Autosomal recessive hypercholesterolaemia in Sardinia, Italy, and mutations in ARH: a clinical and molecular genetic analysis. Lancet (2002) 1.69
Discovering the full spectrum of cardiovascular disease: Minority Health Summit 2003: report of the Obesity, Metabolic Syndrome, and Hypertension Writing Group. Circulation (2005) 1.67
Stimulation of cholesterol excretion by the liver X receptor agonist requires ATP-binding cassette transporters G5 and G8. J Biol Chem (2003) 1.67
Success in control of hypertension in a low-resource setting: the Cuban experience. J Hypertens (2006) 1.64
Genetic variation in ANGPTL4 provides insights into protein processing and function. J Biol Chem (2009) 1.64
Left atrial structure and function and clinical outcomes in the general population. Eur Heart J (2012) 1.64
Association between blood pressure and resting energy expenditure independent of body size. Hypertension (2004) 1.62
Relationship between C-reactive protein and subclinical atherosclerosis: the Dallas Heart Study. Circulation (2005) 1.58
Expression of ABCG5 and ABCG8 is required for regulation of biliary cholesterol secretion. J Biol Chem (2004) 1.57
Normal sorting but defective endocytosis of the low density lipoprotein receptor in mice with autosomal recessive hypercholesterolemia. J Biol Chem (2003) 1.56
Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations. Am J Hum Genet (2013) 1.55
Race and ancestry in biomedical research: exploring the challenges. Genome Med (2009) 1.55
Validation of a research case definition of Gulf War illness in the 1991 US military population. Neuroepidemiology (2011) 1.54
Combined admixture mapping and association analysis identifies a novel blood pressure genetic locus on 5p13: contributions from the CARe consortium. Hum Mol Genet (2011) 1.54
Expression and characterization of a PNPLA3 protein isoform (I148M) associated with nonalcoholic fatty liver disease. J Biol Chem (2011) 1.53
Epidemiological similarities between appendicitis and diverticulitis suggesting a common underlying pathogenesis. Arch Surg (2011) 1.53
The Nigerian antihypertensive adherence trial: a community-based randomized trial. J Hypertens (2013) 1.52
Racial and ethnic differences in hospice enrollment among children with cancer. Pediatr Blood Cancer (2013) 1.51