Published in Proc Natl Acad Sci U S A on June 21, 2004
Membrane vesicles as conveyors of immune responses. Nat Rev Immunol (2009) 14.72
Extracellular vesicles: exosomes, microvesicles, and friends. J Cell Biol (2013) 10.02
Propagation of tau misfolding from the outside to the inside of a cell. J Biol Chem (2009) 5.76
Rab27a and Rab27b control different steps of the exosome secretion pathway. Nat Cell Biol (2009) 5.44
Alzheimer's disease beta-amyloid peptides are released in association with exosomes. Proc Natl Acad Sci U S A (2006) 3.98
Cell-produced alpha-synuclein is secreted in a calcium-dependent manner by exosomes and impacts neuronal survival. J Neurosci (2010) 3.81
Prion-like mechanisms in neurodegenerative diseases. Nat Rev Neurosci (2009) 3.68
Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease. J Biol Chem (2011) 3.57
Prions hijack tunnelling nanotubes for intercellular spread. Nat Cell Biol (2009) 3.55
Melanosomes--dark organelles enlighten endosomal membrane transport. Nat Rev Mol Cell Biol (2007) 3.19
Biological properties of extracellular vesicles and their physiological functions. J Extracell Vesicles (2015) 3.02
Exosomes: secreted vesicles and intercellular communications. F1000 Biol Rep (2011) 2.95
Serum microRNAs as non-invasive biomarkers for cancer. Mol Cancer (2010) 2.95
Getting a grip on prions: oligomers, amyloids, and pathological membrane interactions. Annu Rev Biochem (2009) 2.80
The Silver locus product Pmel17/gp100/Silv/ME20: controversial in name and in function. Pigment Cell Res (2005) 2.71
Neurotransmitter-triggered transfer of exosomes mediates oligodendrocyte-neuron communication. PLoS Biol (2013) 2.61
Exosomes: immune properties and potential clinical implementations. Semin Immunopathol (2010) 2.60
Characterization and comprehensive proteome profiling of exosomes secreted by hepatocytes. J Proteome Res (2008) 2.41
Lysosomal dysfunction increases exosome-mediated alpha-synuclein release and transmission. Neurobiol Dis (2011) 2.32
Higher-order oligomerization targets plasma membrane proteins and HIV gag to exosomes. PLoS Biol (2007) 2.30
Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells. Nucleic Acids Res (2012) 2.18
Exosomal cell-to-cell transmission of alpha synuclein oligomers. Mol Neurodegener (2012) 2.11
Microvesicles and viral infection. J Virol (2011) 2.10
Proteomics analysis of A33 immunoaffinity-purified exosomes released from the human colon tumor cell line LIM1215 reveals a tissue-specific protein signature. Mol Cell Proteomics (2009) 2.08
Microvesicle entry into marrow cells mediates tissue-specific changes in mRNA by direct delivery of mRNA and induction of transcription. Exp Hematol (2010) 2.01
Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT). J Proteome Res (2009) 1.97
Exosome/microvesicle-mediated epigenetic reprogramming of cells. Am J Cancer Res (2010) 1.96
Exosomal transfer of proteins and RNAs at synapses in the nervous system. Biol Direct (2007) 1.93
Alteration of marrow cell gene expression, protein production, and engraftment into lung by lung-derived microvesicles: a novel mechanism for phenotype modulation. Stem Cells (2007) 1.92
SUMOylation promotes de novo targeting of HP1α to pericentric heterochromatin. Nat Genet (2011) 1.85
Cell-to-cell transmission of non-prion protein aggregates. Nat Rev Neurol (2010) 1.81
Small misfolded Tau species are internalized via bulk endocytosis and anterogradely and retrogradely transported in neurons. J Biol Chem (2012) 1.79
MicroRNAs as potential biomarkers in human solid tumors. Cancer Lett (2012) 1.73
Identification and proteomic profiling of exosomes in human cerebrospinal fluid. J Transl Med (2012) 1.70
Cardiomyocyte microvesicles contain DNA/RNA and convey biological messages to target cells. PLoS One (2012) 1.67
Sphingolipid-modulated exosome secretion promotes clearance of amyloid-β by microglia. J Biol Chem (2012) 1.66
Exosomes: vehicles for the transfer of toxic proteins associated with neurodegenerative diseases? Front Physiol (2012) 1.65
Extracellular Vesicles from Trypanosoma brucei Mediate Virulence Factor Transfer and Cause Host Anemia. Cell (2016) 1.65
Suppression of dynamin GTPase decreases α-synuclein uptake by neuronal and oligodendroglial cells: a potent therapeutic target for synucleinopathy. Mol Neurodegener (2012) 1.63
Microfluidic isolation and transcriptome analysis of serum microvesicles. Lab Chip (2009) 1.61
Protein targeting to exosomes/microvesicles by plasma membrane anchors. J Biol Chem (2011) 1.56
Retrovirus infection strongly enhances scrapie infectivity release in cell culture. EMBO J (2006) 1.53
The role of exosomes in the processing of proteins associated with neurodegenerative diseases. Eur Biophys J (2007) 1.50
Exosomes as intercellular signaling organelles involved in health and disease: basic science and clinical applications. Int J Mol Sci (2013) 1.50
Role of exosomes/microvesicles in the nervous system and use in emerging therapies. Front Physiol (2012) 1.49
Emerging roles of exosomes in neuron-glia communication. Front Physiol (2012) 1.44
Astrocytes regulate GluR2 expression in motor neurons and their vulnerability to excitotoxicity. Proc Natl Acad Sci U S A (2007) 1.42
Electron tomography of early melanosomes: implications for melanogenesis and the generation of fibrillar amyloid sheets. Proc Natl Acad Sci U S A (2008) 1.40
Emerging roles of exosomes in normal and pathological conditions: new insights for diagnosis and therapeutic applications. Front Immunol (2015) 1.37
Mouse-adapted scrapie infection of SN56 cells: greater efficiency with microsome-associated versus purified PrP-res. J Virol (2006) 1.35
The paradoxical dynamism of marrow stem cells: considerations of stem cells, niches, and microvesicles. Stem Cell Rev (2008) 1.34
Coinfecting prion strains compete for a limiting cellular resource. J Virol (2010) 1.32
Exosomes: mediators of neurodegeneration, neuroprotection and therapeutics. Mol Neurobiol (2013) 1.32
Extracellular vesicles as an emerging mechanism of cell-to-cell communication. Endocrine (2012) 1.32
Exosomes: vesicular carriers for intercellular communication in neurodegenerative disorders. Cell Tissue Res (2012) 1.31
The DEK nuclear autoantigen is a secreted chemotactic factor. Mol Cell Biol (2006) 1.27
Gene expression alterations in brains of mice infected with three strains of scrapie. BMC Genomics (2006) 1.27
Exosome mimetics: a novel class of drug delivery systems. Int J Nanomedicine (2012) 1.27
A deadly spread: cellular mechanisms of α-synuclein transfer. Cell Death Differ (2011) 1.27
Transfer of extracellular vesicles during immune cell-cell interactions. Immunol Rev (2013) 1.25
Misfolded protein aggregates: mechanisms, structures and potential for disease transmission. Semin Cell Dev Biol (2011) 1.25
Emerging role of neuronal exosomes in the central nervous system. Front Physiol (2012) 1.25
Horizontal transfer of RNAs: exosomes as mediators of intercellular communication. Wiley Interdiscip Rev RNA (2011) 1.23
Tunnelling nanotubes: a highway for prion spreading? Prion (2009) 1.22
Stem cell plasticity revisited: the continuum marrow model and phenotypic changes mediated by microvesicles. Exp Hematol (2010) 1.22
Paired helical filaments from Alzheimer disease brain induce intracellular accumulation of Tau protein in aggresomes. J Biol Chem (2012) 1.22
Candidate biomarkers in exosome-like vesicles purified from rat and mouse urine samples. Proteomics Clin Appl (2010) 1.21
Prion uptake in the gut: identification of the first uptake and replication sites. PLoS Pathog (2011) 1.21
Cellular phenotype switching and microvesicles. Adv Drug Deliv Rev (2010) 1.21
Multifaceted roles of tunneling nanotubes in intercellular communication. Front Physiol (2012) 1.21
Exosomes packaging APOBEC3G confer human immunodeficiency virus resistance to recipient cells. J Virol (2008) 1.20
Progenitor/stem cell fate determination: interactive dynamics of cell cycle and microvesicles. Stem Cells Dev (2012) 1.19
Stress-protective signalling of prion protein is corrupted by scrapie prions. EMBO J (2008) 1.18
Normal and disordered reticulocyte maturation. Curr Opin Hematol (2011) 1.16
Pom33, a novel transmembrane nucleoporin required for proper nuclear pore complex distribution. J Cell Biol (2010) 1.16
The exosome secretory pathway transports amyloid precursor protein carboxyl-terminal fragments from the cell into the brain extracellular space. J Biol Chem (2012) 1.16
Protein aggregate spreading in neurodegenerative diseases: problems and perspectives. Neurosci Res (2011) 1.15
LRRK2 secretion in exosomes is regulated by 14-3-3. Hum Mol Genet (2013) 1.15
More insights into the immunosuppressive potential of tumor exosomes. J Transl Med (2008) 1.14
Multivesicular bodies in neurons: distribution, protein content, and trafficking functions. Prog Neurobiol (2011) 1.14
The immunobiology of prion diseases. Nat Rev Immunol (2013) 1.13
Microglial microvesicle secretion and intercellular signaling. Front Physiol (2012) 1.12
Exosomes as mediators of neuroinflammation. J Neuroinflammation (2014) 1.12
Extracellular vesicles including exosomes are mediators of signal transduction: are they protective or pathogenic? Proteomics (2014) 1.09
The role of the cellular prion protein in the immune system. Clin Exp Immunol (2006) 1.09
Follicular dendritic cell-specific prion protein (PrP) expression alone is sufficient to sustain prion infection in the spleen. PLoS Pathog (2011) 1.09
Specific biarsenical labeling of cell surface proteins allows fluorescent- and biotin-tagging of amyloid precursor protein and prion proteins. Mol Biol Cell (2008) 1.08
Stable cell fate changes in marrow cells induced by lung-derived microvesicles. J Extracell Vesicles (2012) 1.07
Abrogation of complex glycosylation by swainsonine results in strain- and cell-specific inhibition of prion replication. J Biol Chem (2011) 1.06
Hyperphosphorylation and cleavage at D421 enhance tau secretion. PLoS One (2012) 1.06
Characterization of human thymic exosomes. PLoS One (2013) 1.05
Emergence and natural selection of drug-resistant prions. Mol Biosyst (2010) 1.05
Potential contribution of exosomes to the prion-like propagation of lesions in Alzheimer's disease. Front Physiol (2012) 1.05
Extracellular Tau levels are influenced by variability in Tau that is associated with tauopathies. J Biol Chem (2012) 1.05
Formation and propagation of tau oligomeric seeds. Front Neurol (2013) 1.04
Signaling pathways in exosomes biogenesis, secretion and fate. Genes (Basel) (2013) 1.04
Prions and the potential transmissibility of protein misfolding diseases. Annu Rev Microbiol (2013) 1.04
Lung injury and cancer: Mechanistic insights into ceramide and EGFR signaling under cigarette smoke. Am J Respir Cell Mol Biol (2010) 1.03
Exosomes/miRNAs as mediating cell-based therapy of stroke. Front Cell Neurosci (2014) 1.03
Prediction of conversion from mild cognitive impairment to dementia with neuronally derived blood exosome protein profile. Alzheimers Dement (Amst) (2016) 1.02
Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels. Anal Chem (1996) 45.70
Functional rafts in cell membranes. Nature (1997) 38.89
Prions. Proc Natl Acad Sci U S A (1998) 27.80
Exosomes: composition, biogenesis and function. Nat Rev Immunol (2002) 13.99
B lymphocytes secrete antigen-presenting vesicles. J Exp Med (1996) 11.53
Eradication of established murine tumors using a novel cell-free vaccine: dendritic cell-derived exosomes. Nat Med (1998) 6.36
Proteomic analysis of dendritic cell-derived exosomes: a secreted subcellular compartment distinct from apoptotic vesicles. J Immunol (2001) 6.32
Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming. Nat Med (2001) 5.71
Malignant effusions and immunogenic tumour-derived exosomes. Lancet (2002) 4.91
Molecular characterization of dendritic cell-derived exosomes. Selective accumulation of the heat shock protein hsc73. J Cell Biol (1999) 4.87
Amyloidogenic processing of the Alzheimer beta-amyloid precursor protein depends on lipid rafts. J Cell Biol (2003) 4.71
The biogenesis and functions of exosomes. Traffic (2002) 4.49
Proteomic and biochemical analyses of human B cell-derived exosomes. Potential implications for their function and multivesicular body formation. J Biol Chem (2003) 4.14
Indirect activation of naïve CD4+ T cells by dendritic cell-derived exosomes. Nat Immunol (2002) 3.78
Electron microscopic evidence for externalization of the transferrin receptor in vesicular form in sheep reticulocytes. J Cell Biol (1985) 3.63
Intestinal epithelial cells secrete exosome-like vesicles. Gastroenterology (2001) 3.33
Flotillin and epidermal surface antigen define a new family of caveolae-associated integral membrane proteins. J Biol Chem (1997) 3.14
Cholera toxin: interaction of subunits with ganglioside GM1. Science (1974) 3.11
Lipid raft-associated protein sorting in exosomes. Blood (2003) 2.76
Transfer of scrapie prion infectivity by cell contact in culture. Curr Biol (2002) 2.54
Characterization of detergent-insoluble complexes containing the cellular prion protein and its scrapie isoform. J Biol Chem (1997) 2.48
Follicular dendritic cells carry MHC class II-expressing microvesicles at their surface. J Immunol (2000) 2.36
A hypothalamic neuronal cell line persistently infected with scrapie prions exhibits apoptosis. J Virol (1997) 2.32
Recycling compartments and the internal vesicles of multivesicular bodies harbor most of the cholesterol found in the endocytic pathway. Traffic (2003) 2.30
Ex vivo propagation of infectious sheep scrapie agent in heterologous epithelial cells expressing ovine prion protein. Proc Natl Acad Sci U S A (2001) 2.16
Conversion of raft associated prion protein to the protease-resistant state requires insertion of PrP-res (PrP(Sc)) into contiguous membranes. EMBO J (2002) 2.16
Differential sorting and fate of endocytosed GPI-anchored proteins. EMBO J (2002) 2.15
Ultrastructural localization of scrapie prion proteins in cytoplasmic vesicles of infected cultured cells. Lab Invest (1991) 2.13
Mast cell-dependent B and T lymphocyte activation is mediated by the secretion of immunologically active exosomes. J Immunol (2001) 1.91
Markedly increased susceptibility to natural sheep scrapie of transgenic mice expressing ovine prp. J Virol (2001) 1.86
Intercellular transfer of the cellular prion protein. J Biol Chem (2002) 1.54
Trafficking of prion proteins through a caveolae-mediated endosomal pathway. J Cell Biol (2003) 1.51
Cellular biology of prion diseases. Clin Microbiol Rev (1999) 1.48
Transmission of prions. Proc Natl Acad Sci U S A (2002) 1.36
Cultured peripheral neuroglial cells are highly permissive to sheep prion infection. J Virol (2004) 1.19
Decay-accelerating factor (CD55) and membrane inhibitor of reactive lysis (CD59) are released within exosomes during In vitro maturation of reticulocytes. Blood (1998) 1.17
Cellular and subcellular morphological localization of normal prion protein in rodent cerebellum. Eur J Neurosci (2001) 1.08
Lysosome-related organelles: a view from immunity and pigmentation. Cell Struct Funct (2002) 1.05
Characteristics of the interaction between Hsc70 and the transferrin receptor in exosomes released during reticulocyte maturation. J Biol Chem (2000) 1.01
Peripheral pathogenesis of prion diseases. Microbes Infect (2000) 0.98
Isolation and characterization of exosomes from cell culture supernatants and biological fluids. Curr Protoc Cell Biol (2006) 13.29
Exosomes--vesicular carriers for intercellular communication. Curr Opin Cell Biol (2009) 6.96
Exosomal-like vesicles are present in human blood plasma. Int Immunol (2005) 6.04
Exosomes: a common pathway for a specialized function. J Biochem (2006) 5.79
Exosomes: endosomal-derived vesicles shipping extracellular messages. Curr Opin Cell Biol (2004) 5.71
Rab27a and Rab27b control different steps of the exosome secretion pathway. Nat Cell Biol (2009) 5.44
NOX2 controls phagosomal pH to regulate antigen processing during crosspresentation by dendritic cells. Cell (2006) 5.35
Munc13-4 is essential for cytolytic granules fusion and is mutated in a form of familial hemophagocytic lymphohistiocytosis (FHL3). Cell (2003) 4.94
The biogenesis and functions of exosomes. Traffic (2002) 4.49
The Arp2/3 activator WASH controls the fission of endosomes through a large multiprotein complex. Dev Cell (2009) 4.00
Biogenesis, secretion, and intercellular interactions of exosomes and other extracellular vesicles. Annu Rev Cell Dev Biol (2014) 3.97
Cells respond to mechanical stress by rapid disassembly of caveolae. Cell (2011) 3.55
Shiga toxin induces tubular membrane invaginations for its uptake into cells. Nature (2007) 3.51
Exosome secretion: molecular mechanisms and roles in immune responses. Traffic (2011) 3.36
TCR activation of human T cells induces the production of exosomes bearing the TCR/CD3/zeta complex. J Immunol (2002) 3.28
A novel dendritic cell subset involved in tumor immunosurveillance. Nat Med (2006) 3.21
Vesiclepedia: a compendium for extracellular vesicles with continuous community annotation. PLoS Biol (2012) 3.18
As we wait: coping with an imperfect nomenclature for extracellular vesicles. J Extracell Vesicles (2013) 3.01
Regulation of dendritic cell migration by CD74, the MHC class II-associated invariant chain. Science (2008) 2.88
Rab38 and Rab32 control post-Golgi trafficking of melanogenic enzymes. J Cell Biol (2006) 2.79
Lipid raft-associated protein sorting in exosomes. Blood (2003) 2.76
Exosome release is regulated by a calcium-dependent mechanism in K562 cells. J Biol Chem (2003) 2.71
The Silver locus product Pmel17/gp100/Silv/ME20: controversial in name and in function. Pigment Cell Res (2005) 2.71
Rab27a regulates phagosomal pH and NADPH oxidase recruitment to dendritic cell phagosomes. Nat Cell Biol (2007) 2.69
Inhibition of retrograde transport protects mice from lethal ricin challenge. Cell (2010) 2.67
Functions of adaptor protein (AP)-3 and AP-1 in tyrosinase sorting from endosomes to melanosomes. Mol Biol Cell (2005) 2.56
Regulation of retromer recruitment to endosomes by sequential action of Rab5 and Rab7. J Cell Biol (2008) 2.56
Screening of 145 anti-PrP monoclonal antibodies for their capacity to inhibit PrPSc replication in infected cells. J Biol Chem (2004) 2.54
A newly identified type of scrapie agent can naturally infect sheep with resistant PrP genotypes. Proc Natl Acad Sci U S A (2005) 2.47
BLOC-1 interacts with BLOC-2 and the AP-3 complex to facilitate protein trafficking on endosomes. Mol Biol Cell (2006) 2.37
BSE agent signatures in a goat. Vet Rec (2005) 2.35
ICAM-1 on exosomes from mature dendritic cells is critical for efficient naive T-cell priming. Blood (2005) 2.34
A lumenal domain-dependent pathway for sorting to intralumenal vesicles of multivesicular endosomes involved in organelle morphogenesis. Dev Cell (2006) 2.29
Secretory cytotoxic granule maturation and exocytosis require the effector protein hMunc13-4. Nat Immunol (2007) 2.28
Facilitated cross-species transmission of prions in extraneural tissue. Science (2012) 2.26
Cell-specific ATP7A transport sustains copper-dependent tyrosinase activity in melanosomes. Nature (2008) 2.15
Proprotein convertase cleavage liberates a fibrillogenic fragment of a resident glycoprotein to initiate melanosome biogenesis. J Cell Biol (2003) 2.12
The exosome pathway in K562 cells is regulated by Rab11. J Cell Sci (2002) 2.11
BLOC-1 is required for cargo-specific sorting from vacuolar early endosomes toward lysosome-related organelles. Mol Biol Cell (2006) 2.11
Multifocal structure of the T cell - dendritic cell synapse. Eur J Immunol (2005) 2.09
Diverse subpopulations of vesicles secreted by different intracellular mechanisms are present in exosome preparations obtained by differential ultracentrifugation. J Extracell Vesicles (2012) 2.06
ARF6 controls post-endocytic recycling through its downstream exocyst complex effector. J Cell Biol (2003) 2.02
AP-1 and KIF13A coordinate endosomal sorting and positioning during melanosome biogenesis. J Cell Biol (2009) 1.99
MHC II in dendritic cells is targeted to lysosomes or T cell-induced exosomes via distinct multivesicular body pathways. Traffic (2009) 1.98
Analysis of ESCRT functions in exosome biogenesis, composition and secretion highlights the heterogeneity of extracellular vesicles. J Cell Sci (2013) 1.98
A dual mechanism controlling the localization and function of exocytic v-SNAREs. Proc Natl Acad Sci U S A (2003) 1.86
Exosomes as potent cell-free peptide-based vaccine. I. Dendritic cell-derived exosomes transfer functional MHC class I/peptide complexes to dendritic cells. J Immunol (2004) 1.86
SUMOylation promotes de novo targeting of HP1α to pericentric heterochromatin. Nat Genet (2011) 1.85
Endosomes, exosomes and Trojan viruses. Trends Microbiol (2004) 1.84
The tetraspanin CD63 regulates ESCRT-independent and -dependent endosomal sorting during melanogenesis. Dev Cell (2011) 1.82
Prion agent diversity and species barrier. Vet Res (2008) 1.80
The retromer complex and clathrin define an early endosomal retrograde exit site. J Cell Sci (2007) 1.80
Identification of the epitope region capable of inducing neutralizing antibodies against the porcine epidemic diarrhea virus. Mol Cells (2002) 1.77
Involvement of caspase-cleaved and intact adaptor protein 1 complex in endosomal remodeling in maturing dendritic cells. Nat Immunol (2005) 1.76
Crystal structures of the SH2 domain of Grb2: highlight on the binding of a new high-affinity inhibitor. J Mol Biol (2002) 1.75
A bovine prion acquires an epidemic bovine spongiform encephalopathy strain-like phenotype on interspecies transmission. J Neurosci (2007) 1.75
TI-VAMP/VAMP7 is required for optimal phagocytosis of opsonised particles in macrophages. EMBO J (2004) 1.71
Diaphanous-related formins are required for invadopodia formation and invasion of breast tumor cells. Cancer Res (2009) 1.63
T84-intestinal epithelial exosomes bear MHC class II/peptide complexes potentiating antigen presentation by dendritic cells. Gastroenterology (2007) 1.60
The physical relationship between infectivity and prion protein aggregates is strain-dependent. PLoS Pathog (2010) 1.59
Lysosome-related organelles: unusual compartments become mainstream. Curr Opin Cell Biol (2013) 1.59
Generation of a replication-competent, propagation-deficient virus vector based on the transmissible gastroenteritis coronavirus genome. J Virol (2002) 1.57
Isolation from cattle of a prion strain distinct from that causing bovine spongiform encephalopathy. PLoS Pathog (2006) 1.55
Retrovirus infection strongly enhances scrapie infectivity release in cell culture. EMBO J (2006) 1.53
Sarcopenia predicts early dose-limiting toxicities and pharmacokinetics of sorafenib in patients with hepatocellular carcinoma. PLoS One (2012) 1.53
ARF6 Interacts with JIP4 to control a motor switch mechanism regulating endosome traffic in cytokinesis. Curr Biol (2009) 1.52
Synchronization of secretory protein traffic in populations of cells. Nat Methods (2012) 1.41
Exosomes bearing HLA-DR1 molecules need dendritic cells to efficiently stimulate specific T cells. Int Immunol (2002) 1.41
Rab27A and its effector MyRIP link secretory granules to F-actin and control their motion towards release sites. J Cell Biol (2003) 1.40
Transgenesis applied to transmissible spongiform encephalopathies. Transgenic Res (2002) 1.38
Transmission of atypical bovine prions to mice transgenic for human prion protein. Emerg Infect Dis (2008) 1.38
Sheep and goat BSE propagate more efficiently than cattle BSE in human PrP transgenic mice. PLoS Pathog (2011) 1.38
The Wave complex is intrinsically inactive. Cell Motil Cytoskeleton (2009) 1.37
Dual loss of ER export and endocytic signals with altered melanosome morphology in the silver mutation of Pmel17. Mol Biol Cell (2006) 1.37
Exosome secretion: the art of reutilizing nonrecycled proteins? Traffic (2004) 1.37
Mouse neuroblastoma cells release prion infectivity associated with exosomal vesicles. Biol Cell (2008) 1.33
Reticulocyte membrane remodeling: contribution of the exosome pathway. Curr Opin Hematol (2010) 1.31
Degradation of AP2 during reticulocyte maturation enhances binding of hsc70 and Alix to a common site on TFR for sorting into exosomes. Traffic (2004) 1.31
Highly efficient prion transmission by blood transfusion. PLoS Pathog (2012) 1.30
Analysis of articulation between clathrin and retromer in retrograde sorting on early endosomes. Traffic (2009) 1.30
Reduced phosphatase activity of SHP-2 in LEOPARD syndrome: consequences for PI3K binding on Gab1. FEBS Lett (2006) 1.30
N-terminal domains elicit formation of functional Pmel17 amyloid fibrils. J Biol Chem (2009) 1.28
The fission yeast Nup107-120 complex functionally interacts with the small GTPase Ran/Spi1 and is required for mRNA export, nuclear pore distribution, and proper cell division. Mol Cell Biol (2004) 1.27
Galectin-5 is bound onto the surface of rat reticulocyte exosomes and modulates vesicle uptake by macrophages. Blood (2009) 1.27
The synaptic acetylcholinesterase tetramer assembles around a polyproline II helix. EMBO J (2004) 1.27
Prions can infect primary cultured neurons and astrocytes and promote neuronal cell death. Proc Natl Acad Sci U S A (2004) 1.27
Atypical/Nor98 scrapie infectivity in sheep peripheral tissues. PLoS Pathog (2011) 1.26
Engrailed protects mouse midbrain dopaminergic neurons against mitochondrial complex I insults. Nat Neurosci (2011) 1.24
Prominent and persistent extraneural infection in human PrP transgenic mice infected with variant CJD. PLoS One (2008) 1.24
Exosomes: a bubble ride for prions? Traffic (2005) 1.24
Proteomic analysis of secreted exosomes. Subcell Biochem (2007) 1.22
Rab27b regulates mast cell granule dynamics and secretion. Traffic (2007) 1.22
Birbeck granules are subdomains of endosomal recycling compartment in human epidermal Langerhans cells, which form where Langerin accumulates. Mol Biol Cell (2002) 1.21
Cultured peripheral neuroglial cells are highly permissive to sheep prion infection. J Virol (2004) 1.19
Human immunodeficiency virus-1 Nef expression induces intracellular accumulation of multivesicular bodies and major histocompatibility complex class II complexes: potential role of phosphatidylinositol 3-kinase. Mol Biol Cell (2003) 1.18
The actin-based motor protein myosin II regulates MHC class II trafficking and BCR-driven antigen presentation. J Cell Biol (2007) 1.17