Published in Stem Cells on January 01, 2004
Protective effects of human iPS-derived retinal pigment epithelium cell transplantation in the retinal dystrophic rat. PLoS One (2009) 2.54
Short-term immunosuppression promotes engraftment of embryonic and induced pluripotent stem cells. Cell Stem Cell (2011) 2.35
Immunosuppressive therapy mitigates immunological rejection of human embryonic stem cell xenografts. Proc Natl Acad Sci U S A (2008) 2.25
Developing safe therapies from human pluripotent stem cells. Nat Biotechnol (2009) 1.48
In vivo imaging of embryonic stem cells reveals patterns of survival and immune rejection following transplantation. Stem Cells Dev (2008) 1.46
Scalable stirred-suspension bioreactor culture of human pluripotent stem cells. Tissue Eng Part A (2010) 1.44
Negligible immunogenicity of induced pluripotent stem cells derived from human skin fibroblasts. PLoS One (2014) 1.38
Risk factors in the development of stem cell therapy. J Transl Med (2011) 1.38
Embryonic stem cell-derived tissues are immunogenic but their inherent immune privilege promotes the induction of tolerance. Proc Natl Acad Sci U S A (2007) 1.34
Survival and maturation of human embryonic stem cell-derived cardiomyocytes in rat hearts. J Mol Cell Cardiol (2007) 1.23
HLA engineering of human pluripotent stem cells. Mol Ther (2013) 1.19
Immunological considerations for embryonic and induced pluripotent stem cell banking. Philos Trans R Soc Lond B Biol Sci (2011) 1.17
Regeneration of the pancreatic beta cell. J Clin Invest (2005) 1.14
Epigenetic mechanisms regulate MHC and antigen processing molecules in human embryonic and induced pluripotent stem cells. PLoS One (2010) 1.11
Converting human pluripotent stem cells into beta-cells: recent advances and future challenges. Curr Opin Organ Transplant (2010) 1.07
Development of histocompatible primate-induced pluripotent stem cells for neural transplantation. Stem Cells (2011) 1.07
The immune response of stem cells in subretinal transplantation. Stem Cell Res Ther (2015) 1.05
Concise review: mind the gap: challenges in characterizing and quantifying cell- and tissue-based therapies for clinical translation. Stem Cells (2010) 1.04
Achieving stable human stem cell engraftment and survival in the CNS: is the future of regenerative medicine immunodeficient? Regen Med (2011) 1.03
Multipotent adult germ-line stem cells, like other pluripotent stem cells, can be killed by cytotoxic T lymphocytes despite low expression of major histocompatibility complex class I molecules. Biol Direct (2009) 0.98
Potential barriers to therapeutics utilizing pluripotent cell derivatives: intrinsic immunogenicity of in vitro maintained and matured populations. Semin Immunopathol (2011) 0.98
Stem cells for heart cell therapies. Tissue Eng Part B Rev (2008) 0.98
Pluripotent stem cells: immune to the immune system? Sci Transl Med (2012) 0.97
Safety of human embryonic stem cells in patients with terminal/incurable conditions- a retrospective analysis. Ann Neurosci (2015) 0.96
Effects of histocompatibility and host immune responses on the tumorigenicity of pluripotent stem cells. Semin Immunopathol (2011) 0.94
Neural progenitors derived from human embryonic stem cells are targeted by allogeneic T and natural killer cells. J Cell Mol Med (2009) 0.93
MHC mismatch inhibits neurogenesis and neuron maturation in stem cell allografts. PLoS One (2011) 0.93
Equivalence of conventionally-derived and parthenote-derived human embryonic stem cells. PLoS One (2011) 0.92
Ocular immune privilege and ocular melanoma: parallel universes or immunological plagiarism? Front Immunol (2012) 0.90
Stem cell microchimerism and tolerance to non-inherited maternal antigens. Chimerism (2016) 0.89
MHC mismatch results in neural progenitor cell rejection following spinal cord transplantation in a model of viral-induced demyelination. Stem Cells (2012) 0.89
Stem cells for retinal replacement therapy. Neurotherapeutics (2011) 0.88
Embryonic and induced pluripotent stem cells: understanding, creating, and exploiting the nano-niche for regenerative medicine. ACS Nano (2013) 0.87
Transcriptional profiling of putative human epithelial stem cells. BMC Genomics (2008) 0.87
Immunological properties of embryonic and adult stem cells. World J Stem Cells (2010) 0.87
Potential and limitation of HLA-based banking of human pluripotent stem cells for cell therapy. J Immunol Res (2014) 0.86
Combination stem cell therapy for heart failure. Int Arch Med (2010) 0.85
Modulating the biochemical and biophysical culture environment to enhance osteogenic differentiation and maturation of human pluripotent stem cell-derived mesenchymal progenitors. Stem Cell Res Ther (2013) 0.85
Subcutaneous transplantation of embryonic pancreas for correction of type 1 diabetes. Am J Physiol Endocrinol Metab (2008) 0.85
Equine mesenchymal stromal cells and embryo-derived stem cells are immune privileged in vitro. Stem Cell Res Ther (2014) 0.84
In vitro immunogenicity of undifferentiated pluripotent stem cells (PSC) and derived lineages. Semin Immunopathol (2011) 0.84
Human embryonic stem cells hemangioblast express HLA-antigens. J Transl Med (2009) 0.84
Immune regulation by non-lymphoid cells in transplantation. Clin Exp Immunol (2009) 0.84
Immunogenicity and tumorigenicity of pluripotent stem cells and their derivatives: genetic and epigenetic perspectives. Curr Stem Cell Res Ther (2014) 0.84
Mixed chimerism and split tolerance: mechanisms and clinical correlations. Chimerism (2012) 0.83
Human Induced Pluripotent Stem Cells Are Targets for Allogeneic and Autologous Natural Killer (NK) Cells and Killing Is Partly Mediated by the Activating NK Receptor DNAM-1. PLoS One (2015) 0.82
Pluripotent stem cell derived cardiomyocytes for cardiac repair. Curr Treat Options Cardiovasc Med (2014) 0.82
Immunological barriers to stem-cell based cardiac repair. Stem Cell Rev (2011) 0.81
What is the potential of oligodendrocyte progenitor cells to successfully treat human spinal cord injury? BMC Neurol (2011) 0.81
Cardiac Regeneration and Stem Cells. Physiol Rev (2015) 0.80
Biomedical and clinical promises of human pluripotent stem cells for neurological disorders. Biomed Res Int (2013) 0.80
Activating receptor NKG2D targets RAE-1-expressing allogeneic neural precursor cells in a viral model of multiple sclerosis. Stem Cells (2014) 0.79
Embryonic stem cell-derived factors inhibit T effector activation and induce T regulatory cells by suppressing PKC-θ activation. PLoS One (2012) 0.79
Immunogenicity of in vitro maintained and matured populations: potential barriers to engraftment of human pluripotent stem cell derivatives. Methods Mol Biol (2013) 0.79
Expression of major histocompatibility complex class I proteins and their antigen processing chaperones in mouse embryonic stem cells from fertilized and parthenogenetic embryos. Tissue Antigens (2008) 0.79
How to cross immunogenetic hurdles to human embryonic stem cell transplantation. Semin Immunopathol (2011) 0.79
Ectopic pregnancy-derived human trophoblastic stem cells regenerate dopaminergic nigrostriatal pathway to treat parkinsonian rats. PLoS One (2012) 0.79
Pluripotent stem cell applications for regenerative medicine. Curr Opin Organ Transplant (2015) 0.78
Attenuated Innate Immunity in Embryonic Stem Cells and Its Implications in Developmental Biology and Regenerative Medicine. Stem Cells (2015) 0.78
Human Parthenogenetic Embryonic Stem Cell-Derived Neural Stem Cells Express HLA-G and Show Unique Resistance to NK Cell-Mediated Killing. Mol Med (2015) 0.78
Therapeutic potentials of human embryonic stem cells in Parkinson's disease. Neurotherapeutics (2008) 0.78
Cross-talk between human neural stem/progenitor cells and peripheral blood mononuclear cells in an allogeneic co-culture model. PLoS One (2015) 0.78
Human embryonic stem cell technology: large scale cell amplification and differentiation. Cytotechnology (2006) 0.77
Challenges for the Therapeutic use of Pluripotent Stem Derived Cells. Front Physiol (2012) 0.77
Technical challenges in the derivation of human pluripotent cells. Stem Cells Int (2011) 0.77
The Kynurenine Pathway Is a Double-Edged Sword in Immune-Privileged Sites and in Cancer: Implications for Immunotherapy. Int J Tryptophan Res (2016) 0.76
Separate developmental programs for HLA-A and -B cell surface expression during differentiation from embryonic stem cells to lymphocytes, adipocytes and osteoblasts. PLoS One (2013) 0.76
Transplantation of hESC-derived hepatocytes protects mice from liver injury. Stem Cell Res Ther (2015) 0.76
CD70-CD27 ligation between neural stem cells and CD4+ T cells induces Fas-FasL-mediated T-cell death. Stem Cell Res Ther (2013) 0.75
Therapeutic potential of human embryonic stem cells in type 2 diabetes mellitus. World J Stem Cells (2016) 0.75
Emerging Implications for Extracellular Matrix-Based Technologies in Vascularized Composite Allotransplantation. Stem Cells Int (2015) 0.75
Human Embryonic Stem Cells: A Model for the Study of Neural Development and Neurological Diseases. Stem Cells Int (2016) 0.75
Restoration of a Critical Mandibular Bone Defect Using Human Alveolar Bone-Derived Stem Cells and Porous Nano-HA/Collagen/PLA Scaffold. Stem Cells Int (2016) 0.75
Immune responses to bioengineered organs. Curr Opin Organ Transplant (2016) 0.75
Specific protein markers for stem cell cross-talk with neighboring cells in the environment. Int J Stem Cells (2013) 0.75
Current Biosafety Considerations in Stem Cell Therapy. Cell J (2016) 0.75
HLA and Histo-Blood Group Antigen Expression in Human Pluripotent Stem Cells and their Derivatives. Sci Rep (2017) 0.75
The Immunogenicity and Immune Tolerance of Pluripotent Stem Cell Derivatives. Front Immunol (2017) 0.75
Comparative global immune-related gene profiling of somatic cells, human pluripotent stem cells and their derivatives: implication for human lymphocyte proliferation. Exp Mol Med (2017) 0.75
Direct conversion of human fibroblasts to multilineage blood progenitors. Nature (2010) 5.35
Identification of drugs including a dopamine receptor antagonist that selectively target cancer stem cells. Cell (2012) 4.13
Cytokines and BMP-4 promote hematopoietic differentiation of human embryonic stem cells. Blood (2003) 3.98
IGF and FGF cooperatively establish the regulatory stem cell niche of pluripotent human cells in vitro. Nature (2007) 3.74
Bone marrow-derived stem cells initiate pancreatic regeneration. Nat Biotechnol (2003) 3.02
Endothelial and hematopoietic cell fate of human embryonic stem cells originates from primitive endothelium with hemangioblastic properties. Immunity (2004) 2.89
Characterization of human embryonic stem cells with features of neoplastic progression. Nat Biotechnol (2009) 2.66
Glycogen synthase kinase-3 is an in vivo regulator of hematopoietic stem cell repopulation. Nat Med (2005) 2.60
Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. Nat Biotechnol (2004) 2.60
Isolation of human iPS cells using EOS lentiviral vectors to select for pluripotency. Nat Methods (2009) 2.51
Generation of hematopoietic repopulating cells from human embryonic stem cells independent of ectopic HOXB4 expression. J Exp Med (2005) 2.42
Clonal isolation of hESCs reveals heterogeneity within the pluripotent stem cell compartment. Nat Methods (2006) 2.31
Reversal of mouse hepatic failure using an implanted liver-assist device containing ES cell-derived hepatocytes. Nat Biotechnol (2006) 2.21
MPSS profiling of human embryonic stem cells. BMC Dev Biol (2004) 2.17
Expansion of human embryonic stem cells in defined serum-free medium devoid of animal-derived products. Biotechnol Bioeng (2005) 2.13
Identification of growth factor conditions that reduce ex vivo cord blood progenitor expansion but do not alter human repopulating cell function in vivo. Haematologica (2005) 2.11
Prevention of amino acid conversion in SILAC experiments with embryonic stem cells. Mol Cell Proteomics (2008) 1.83
Tumor suppression by phospholipase C-beta3 via SHP-1-mediated dephosphorylation of Stat5. Cancer Cell (2009) 1.78
Immortalized fibroblast-like cells derived from human embryonic stem cells support undifferentiated cell growth. Stem Cells (2004) 1.74
Wnt-5A augments repopulating capacity and primitive hematopoietic development of human blood stem cells in vivo. Proc Natl Acad Sci U S A (2003) 1.72
Hedgehog modulates cell cycle regulators in stem cells to control hematopoietic regeneration. Proc Natl Acad Sci U S A (2006) 1.71
The histone demethylase KDM5b/JARID1b plays a role in cell fate decisions by blocking terminal differentiation. Mol Cell Biol (2008) 1.67
Human embryonic stem cells maintained in the absence of mouse embryonic fibroblasts or conditioned media are capable of hematopoietic development. Blood (2005) 1.49
VEGF-A165 augments erythropoietic development from human embryonic stem cells. Blood (2003) 1.43
Serum-free derivation of human embryonic stem cell lines on human placental fibroblast feeders. Fertil Steril (2005) 1.39
Efficient generation and cryopreservation of cardiomyocytes derived from human embryonic stem cells. Regen Med (2011) 1.35
Cell fate potential of human pluripotent stem cells is encoded by histone modifications. Cell Stem Cell (2011) 1.30
Regional localization within the bone marrow influences the functional capacity of human HSCs. Cell Stem Cell (2013) 1.29
Bacterial superantigens bypass Lck-dependent T cell receptor signaling by activating a Galpha11-dependent, PLC-beta-mediated pathway. Immunity (2006) 1.26
Direct differentiation of human embryonic stem cells to hepatocyte-like cells exhibiting functional activities. Cloning Stem Cells (2007) 1.25
Surface cytotoxic T lymphocyte-associated antigen 4 partitions within lipid rafts and relocates to the immunological synapse under conditions of inhibition of T cell activation. J Exp Med (2002) 1.24
OP9 stroma augments survival of hematopoietic precursors and progenitors during hematopoietic differentiation from human embryonic stem cells. Stem Cells (2008) 1.24
Differentiation of mouse embryonic stem cells to hepatocyte-like cells by co-culture with human liver nonparenchymal cell lines. Nat Protoc (2007) 1.22
Noncanonical Wnt signaling orchestrates early developmental events toward hematopoietic cell fate from human embryonic stem cells. Cell Stem Cell (2009) 1.20
Monitoring early differentiation events in human embryonic stem cells by massively parallel signature sequencing and expressed sequence tag scan. Stem Cells Dev (2004) 1.15
Human embryonic stem cell-derived cardiomyocytes can be maintained in defined medium without serum. Stem Cells Dev (2006) 1.15
Variations in humanized and defined culture conditions supporting derivation of new human embryonic stem cell lines. Cloning Stem Cells (2006) 1.12
Hematopoietic development from human embryonic stem cell lines. Exp Hematol (2005) 1.11
Analysis of the human fetal liver hematopoietic microenvironment. Stem Cells Dev (2005) 1.10
An enhanced mass spectrometry approach reveals human embryonic stem cell growth factors in culture. Mol Cell Proteomics (2008) 1.09
Distinguishing between mouse and human pluripotent stem cell regulation: the best laid plans of mice and men. Stem Cells (2010) 1.09
Hierarchical and ontogenic positions serve to define the molecular basis of human hematopoietic stem cell behavior. Dev Cell (2005) 1.05
Clonal interrogation of stem cells. Nat Methods (2011) 1.04
Smad7 alters cell fate decisions of human hematopoietic repopulating cells. Blood (2004) 1.02
Signal control of hematopoietic stem cell fate: Wnt, Notch, and Hedgehog as the usual suspects. Curr Opin Hematol (2008) 1.02
Deconstructing human embryonic stem cell cultures: niche regulation of self-renewal and pluripotency. J Mol Med (Berl) (2008) 1.01
Retroviral transduction of hematopoietic cells differentiated from human embryonic stem cell-derived CD45(neg)PFV hemogenic precursors. Mol Ther (2004) 1.01
Clonal tracking of hESCs reveals differential contribution to functional assays. Nat Methods (2010) 1.01
The human stem cell hierarchy is defined by a functional dependence on Mcl-1 for self-renewal capacity. Blood (2010) 1.00
Molecular evidence for OCT4-induced plasticity in adult human fibroblasts required for direct cell fate conversion to lineage specific progenitors. Stem Cells (2014) 0.99
ID1 and ID3 represent conserved negative regulators of human embryonic and induced pluripotent stem cell hematopoiesis. J Cell Sci (2011) 0.98
Genetic manipulation of human embryonic stem cells: a system to study early human development and potential therapeutic applications. Curr Gene Ther (2005) 0.97
Inability of human induced pluripotent stem cell-hematopoietic derivatives to downregulate microRNAs in vivo reveals a block in xenograft hematopoietic regeneration. Stem Cells (2012) 0.96
Human embryonic stem cells: potential tool for achieving immunotolerance? Stem Cell Rev (2005) 0.96
Pluripotent transcription factors possess distinct roles in normal versus transformed human stem cells. PLoS One (2009) 0.96
Pluripotent human stem cell lines: what we can learn about cancer initiation. Trends Mol Med (2008) 0.96
GRNOPC1: the world's first embryonic stem cell-derived therapy. Interview with Jane Lebkowski. Regen Med (2011) 0.96
Genomic organization and evolution of the CX3CR1/CCR8 chemokine receptor locus. J Biol Chem (2003) 0.95
Immunosuppression involving soluble CD83 induces tolerogenic dendritic cells that prevent cardiac allograft rejection. Transplantation (2010) 0.92
Abnormal immunological profile and vaginal microbiota in women prone to urinary tract infections. Clin Vaccine Immunol (2008) 0.92
FcR gamma presence in TCR complex of double-negative T cells is critical for their regulatory function. J Immunol (2006) 0.92
Identification of T-lymphocytic leukemia-initiating stem cells residing in a small subset of patients with acute myeloid leukemic disease. Blood (2011) 0.92
Wnt3a activates dormant c-Kit(-) bone marrow-derived cells with short-term multilineage hematopoietic reconstitution capacity. Stem Cells (2010) 0.92
Formation and hematopoietic differentiation of human embryoid bodies by suspension and hanging drop cultures. Curr Protoc Stem Cell Biol (2007) 0.91
Novel roles for Notch, Wnt and Hedgehog in hematopoesis derived from human pluripotent stem cells. Int J Dev Biol (2010) 0.91
Notch-HES1 signaling axis controls hemato-endothelial fate decisions of human embryonic and induced pluripotent stem cells. Blood (2013) 0.90
In vivo generation of neural tumors from neoplastic pluripotent stem cells models early human pediatric brain tumor formation. Stem Cells (2012) 0.88
Hematopoietic stem cell biology: too much of a Wnt thing. Nat Immunol (2006) 0.88
Complement targeting of nonhuman sialic acid does not mediate cell death of human embryonic stem cells. Nat Med (2006) 0.88
Multiparameter comparisons of embryoid body differentiation toward human stem cell applications. Stem Cell Res (2010) 0.88
A unique population of bone marrow cells migrates to skeletal muscle via hepatocyte growth factor/c-met axis. J Cell Sci (2005) 0.87
Activation of neural cell fate programs toward direct conversion of adult human fibroblasts into tri-potent neural progenitors using OCT-4. Stem Cells Dev (2014) 0.87
Regulation of T-cell activation by phosphodiesterase 4B2 requires its dynamic redistribution during immunological synapse formation. Mol Cell Biol (2003) 0.85
Wilms' tumor 1-associating protein regulates the proliferation of vascular smooth muscle cells. Circ Res (2006) 0.85
Lck is required for activation-induced T cell death after TCR ligation with partial agonists. J Immunol (2004) 0.84
Immunological properties of human embryonic stem cell-derived oligodendrocyte progenitor cells. J Neuroimmunol (2007) 0.84
Intra-bone marrow transplantation facilitates pauci-clonal human hematopoietic repopulation of NOD/SCID/beta2m(-/-) mice. Exp Hematol (2005) 0.84
Engraftment potential of human fetal hematopoietic cells in NOD/SCID mice is not restricted to mitotically quiescent cells. Blood (2002) 0.84
Dendritic cell differentiation induced by a self-peptide derived from apolipoprotein E. J Immunol (2008) 0.84
Human ESC colony formation is dependent on interplay between self-renewing hESCs and unique precursors responsible for niche generation. Cytometry A (2010) 0.84
Australian Aboriginal kinship: a means to enhance maternal well-being. Women Birth (2010) 0.83
Temporal changes in monocyte and macrophage subsets and microglial macrophages following spinal cord injury in the Lys-Egfp-ki mouse model. J Neuroimmunol (2013) 0.83
Derivation and characterization of hematopoietic cells from human embryonic stem cells. Methods Mol Biol (2006) 0.83
Differential gene expression of human stem progenitor cells derived from early stages of in utero human hematopoiesis. Blood (2003) 0.82
Expansive generation of functional airway epithelium from human embryonic stem cells. Stem Cells Transl Med (2013) 0.82