Published in J Am Chem Soc on August 04, 2004
Analysis and optimization of copper-catalyzed azide-alkyne cycloaddition for bioconjugation. Angew Chem Int Ed Engl (2009) 3.81
Glycoproteomic probes for fluorescent imaging of fucosylated glycans in vivo. Proc Natl Acad Sci U S A (2006) 2.70
Copper-catalyzed azide-alkyne cycloaddition (CuAAC) and beyond: new reactivity of copper(I) acetylides. Chem Soc Rev (2010) 2.68
Rapid oxime and hydrazone ligations with aromatic aldehydes for biomolecular labeling. Bioconjug Chem (2008) 2.25
18F labeled nanoparticles for in vivo PET-CT imaging. Bioconjug Chem (2009) 1.78
Mixed azide-terminated monolayers: a platform for modifying electrode surfaces. Langmuir (2006) 1.57
Tailored ligand acceleration of the Cu-catalyzed azide-alkyne cycloaddition reaction: practical and mechanistic implications. J Am Chem Soc (2010) 1.56
Unnatural amino acid incorporation into virus-like particles. Bioconjug Chem (2008) 1.54
Click chemistry in complex mixtures: bioorthogonal bioconjugation. Chem Biol (2014) 1.40
Core-clickable PEG-branch-azide bivalent-bottle-brush polymers by ROMP: grafting-through and clicking-to. J Am Chem Soc (2010) 1.26
Defining criteria for oligomannose immunogens for HIV using icosahedral virus capsid scaffolds. Chem Biol (2010) 1.21
Selective functionalization of independently addressed microelectrodes by electrochemical activation and deactivation of a coupling catalyst. J Am Chem Soc (2006) 1.16
Electrochemically protected copper(I)-catalyzed azide-alkyne cycloaddition. Chembiochem (2008) 0.99
Copper-Catalyzed Azide-Alkyne Click Chemistry for Bioconjugation. Curr Protoc Chem Biol (2011) 0.98
Preparation of 18F-labeled peptides using the copper(I)-catalyzed azide-alkyne 1,3-dipolar cycloaddition. Nat Protoc (2011) 0.97
Peptide tertiary structure nucleation by side-chain crosslinking with metal complexation and double "click" cycloaddition. Chembiochem (2008) 0.93
Advancements in the mechanistic understanding of the copper-catalyzed azide-alkyne cycloaddition. Beilstein J Org Chem (2013) 0.91
Chelation-assisted, copper(II)-acetate-accelerated azide-alkyne cycloaddition. J Org Chem (2010) 0.91
Global amine and acid functional group modification of proteins. Anal Chem (2008) 0.90
Development of melanoma-targeted polymer micelles by conjugation of a melanocortin 1 receptor (MC1R) specific ligand. J Med Chem (2011) 0.89
"Clickable", polymerized liposomes as a versatile and stable platform for rapid optimization of their peripheral compositions. Chem Commun (Camb) (2010) 0.87
Small molecule probes for plant cell wall polysaccharide imaging. Front Plant Sci (2012) 0.86
Combinatorial catalysis employing a visible enzymatic beacon in real time: synthetically versatile (pseudo)halometalation/carbocyclizations. Angew Chem Int Ed Engl (2011) 0.85
Biocompatible click chemistry enabled compartment-specific pH measurement inside E. coli. Nat Commun (2014) 0.82
Kinetics of bulk photo-initiated copper(i)-catalyzed azide-alkyne cycloaddition (CuAAC) polymerizations. Polym Chem (2015) 0.81
An experimental and computational investigation of spontaneous lasso formation in microcin J25. Biophys J (2010) 0.81
Building addressable libraries: a site-selective click-reaction strategy for rapidly assembling mass spectrometry cleavable linkers. Chem Commun (Camb) (2009) 0.79
Anaerobic conditions to reduce oxidation of proteins and to accelerate the copper-catalyzed "Click" reaction with a water-soluble bis(triazole) ligand. Chem Commun (Camb) (2011) 0.79
N-Succinimidyl 3-((4-(4-[(18)F]fluorobutyl)-1H-1,2,3-triazol-1-yl)methyl)-5-(guanidinomethyl)benzoate ([(18)F]SFBTMGMB): a residualizing label for (18)F-labeling of internalizing biomolecules. Org Biomol Chem (2015) 0.78
"Click" immobilization on alkylated silicon substrates: model for the study of surface bound antimicrobial peptides. Chemistry (2011) 0.78
A genetically encoded alkyne directs palladium-mediated protein labeling on live mammalian cell surface. ACS Chem Biol (2014) 0.76
Construction of bis-, tris- and tetrahydrazones by addition of azoalkenes to amines and ammonia. Beilstein J Org Chem (2016) 0.75
Facile purification and click labeling with 2-[(18)F]fluoroethyl azide using solid phase extraction cartridges. Tetrahedron Lett (2014) 0.75
Inactivation of acetylcholinesterase by various fluorophores. J Enzyme Inhib Med Chem (2010) 0.75
Computational studies on the regioselectivity of metal-catalyzed synthesis of 1,2,3 triazoles via click reaction: a review. J Mol Model (2015) 0.75
Continual reproduction of self-assembling oligotriazole peptide nanomaterials. Nat Commun (2017) 0.75
A stepwise huisgen cycloaddition process: copper(I)-catalyzed regioselective "ligation" of azides and terminal alkynes. Angew Chem Int Ed Engl (2002) 24.12
Polytriazoles as copper(I)-stabilizing ligands in catalysis. Org Lett (2004) 5.49
Bioconjugation by copper(I)-catalyzed azide-alkyne [3 + 2] cycloaddition. J Am Chem Soc (2003) 5.34
Analysis and optimization of copper-catalyzed azide-alkyne cycloaddition for bioconjugation. Angew Chem Int Ed Engl (2009) 3.81
Click chemistry in situ: acetylcholinesterase as a reaction vessel for the selective assembly of a femtomolar inhibitor from an array of building blocks. Angew Chem Int Ed Engl (2002) 3.06
Copper(I)-catalyzed synthesis of azoles. DFT study predicts unprecedented reactivity and intermediates. J Am Chem Soc (2005) 2.75
Copper-catalyzed azide-alkyne cycloaddition (CuAAC) and beyond: new reactivity of copper(I) acetylides. Chem Soc Rev (2010) 2.68
Mechanism of the ligand-free CuI-catalyzed azide-alkyne cycloaddition reaction. Angew Chem Int Ed Engl (2005) 2.62
Ruthenium-catalyzed cycloaddition of alkynes and organic azides. J Am Chem Soc (2005) 2.35
"On water": unique reactivity of organic compounds in aqueous suspension. Angew Chem Int Ed Engl (2005) 2.21
Efficiency and fidelity in a click-chemistry route to triazole dendrimers by the copper(i)-catalyzed ligation of azides and alkynes. Angew Chem Int Ed Engl (2004) 2.11
Copper(I)-catalyzed cycloaddition of organic azides and 1-iodoalkynes. Angew Chem Int Ed Engl (2009) 2.10
Rhodium-catalyzed transannulation of 1,2,3-triazoles with nitriles. J Am Chem Soc (2008) 1.86
Labeling live cells by copper-catalyzed alkyne--azide click chemistry. Bioconjug Chem (2010) 1.86
Rhodium-catalyzed enantioselective cyclopropanation of olefins with N-sulfonyl 1,2,3-triazoles. J Am Chem Soc (2009) 1.85
Accelerated bioorthogonal conjugation: a practical method for the ligation of diverse functional molecules to a polyvalent virus scaffold. Bioconjug Chem (2005) 1.84
Ruthenium-catalyzed azide-alkyne cycloaddition: scope and mechanism. J Am Chem Soc (2008) 1.76
Ligand-accelerated Cu-catalyzed azide-alkyne cycloaddition: a mechanistic report. J Am Chem Soc (2007) 1.72
A heteroaryldihydropyrimidine activates and can misdirect hepatitis B virus capsid assembly. Proc Natl Acad Sci U S A (2005) 1.72
Folic acid-mediated targeting of cowpea mosaic virus particles to tumor cells. Chem Biol (2007) 1.70
Label-free quantification of membrane-ligand interactions using backscattering interferometry. Nat Biotechnol (2011) 1.67
Iterative in situ click chemistry creates antibody-like protein-capture agents. Angew Chem Int Ed Engl (2009) 1.64
Natural supramolecular building blocks. Wild-type cowpea mosaic virus. Chem Biol (2002) 1.64
Viral MRI contrast agents: coordination of Gd by native virions and attachment of Gd complexes by azide-alkyne cycloaddition. Chem Commun (Camb) (2007) 1.63
Inhibitors of HIV-1 protease by using in situ click chemistry. Angew Chem Int Ed Engl (2006) 1.63
Global structural changes in hepatitis B virus capsids induced by the assembly effector HAP1. J Virol (2006) 1.59
Tailored ligand acceleration of the Cu-catalyzed azide-alkyne cycloaddition reaction: practical and mechanistic implications. J Am Chem Soc (2010) 1.56
Crosslinking of and coupling to viral capsid proteins by tyrosine oxidation. Chem Biol (2004) 1.55
Designing facial amphiphiles for the stabilization of integral membrane proteins. Angew Chem Int Ed Engl (2007) 1.55
Unnatural amino acid incorporation into virus-like particles. Bioconjug Chem (2008) 1.54
Systemic trafficking of plant virus nanoparticles in mice via the oral route. Virology (2005) 1.53
Bio-distribution, toxicity and pathology of cowpea mosaic virus nanoparticles in vivo. J Control Release (2007) 1.53
A potent and highly selective inhibitor of human alpha-1,3-fucosyltransferase via click chemistry. J Am Chem Soc (2003) 1.53
Benzimidazole and related ligands for Cu-catalyzed azide-alkyne cycloaddition. J Am Chem Soc (2007) 1.50
Icosahedral virus particles as addressable nanoscale building blocks. Angew Chem Int Ed Engl (2002) 1.49
Synthesis and reactivity of rhodium(II) N-triflyl azavinyl carbenes. J Am Chem Soc (2010) 1.45
Hybrid virus-polymer materials. 1. Synthesis and properties of PEG-decorated cowpea mosaic virus. Biomacromolecules (2003) 1.42
Plasma clearance of bacteriophage Qbeta particles as a function of surface charge. J Am Chem Soc (2008) 1.41
In situ click chemistry: probing the binding landscapes of biological molecules. Chem Soc Rev (2010) 1.38
Organic synthesis "on water". Chem Rev (2009) 1.37
Thiol-selective fluorogenic probes for labeling and release. J Am Chem Soc (2009) 1.36
Small-molecule effectors of hepatitis B virus capsid assembly give insight into virus life cycle. J Virol (2008) 1.34
Direct human cartilage repair using three-dimensional bioprinting technology. Tissue Eng Part A (2012) 1.33
Multivalent, bifunctional dendrimers prepared by click chemistry. Chem Commun (Camb) (2005) 1.32
Functional virus-based polymer-protein nanoparticles by atom transfer radical polymerization. J Am Chem Soc (2011) 1.30
The allylic azide rearrangement: achieving selectivity. J Am Chem Soc (2005) 1.30
Natural supramolecular building blocks. Cysteine-added mutants of cowpea mosaic virus. Chem Biol (2002) 1.29
Practical synthesis of amides from in situ generated copper(I) acetylides and sulfonyl azides. Angew Chem Int Ed Engl (2006) 1.29
Chemical modification of viruses and virus-like particles. Curr Top Microbiol Immunol (2009) 1.28
Core-clickable PEG-branch-azide bivalent-bottle-brush polymers by ROMP: grafting-through and clicking-to. J Am Chem Soc (2010) 1.26
On-virus construction of polyvalent glycan ligands for cell-surface receptors. J Am Chem Soc (2008) 1.26
Multivalent display and receptor-mediated endocytosis of transferrin on virus-like particles. Chembiochem (2010) 1.24
Click chemistry: function follows form. Chem Soc Rev (2010) 1.23
Head-to-tail peptide cyclodimerization by copper-catalyzed azide-alkyne cycloaddition. Angew Chem Int Ed Engl (2005) 1.23
Catalytic asymmetric C-H insertions of rhodium(II) azavinyl carbenes. J Am Chem Soc (2011) 1.22
Trapping of hepatitis B virus capsid assembly intermediates by phenylpropenamide assembly accelerators. ACS Chem Biol (2010) 1.21
Defining criteria for oligomannose immunogens for HIV using icosahedral virus capsid scaffolds. Chem Biol (2010) 1.21
Efficient synthesis of 1-sulfonyl-1,2,3-triazoles. Org Lett (2010) 1.19
Microscale NMR screening of new detergents for membrane protein structural biology. J Am Chem Soc (2008) 1.18
Refinement of structural leads for centrally acting oxime reactivators of phosphylated cholinesterases. J Biol Chem (2012) 1.18
Porous silicon as a versatile platform for laser desorption/ionization mass spectrometry. Anal Chem (2001) 1.16
Ruthenium-catalyzed cycloaddition of aryl azides and alkynes. Org Lett (2007) 1.16
Efficient synthesis of 2-substituted-1,2,3-triazoles. Org Lett (2008) 1.15
One-pot synthesis of 1,4-disubstituted 1,2,3-triazoles from in situ generated azides. Org Lett (2004) 1.14
Copper-catalyzed synthesis of N-sulfonyl-1,2,3-triazoles: controlling selectivity. Angew Chem Int Ed Engl (2007) 1.14
New structural scaffolds for centrally acting oxime reactivators of phosphylated cholinesterases. J Biol Chem (2011) 1.14
Rapid diversity-oriented synthesis in microtiter plates for in situ screening of HIV protease inhibitors. Chembiochem (2003) 1.13
One-pot copper(I)-catalyzed synthesis of 3,5-disubstituted isoxazoles. J Org Chem (2005) 1.13
Direct synthesis of 1,5-disubstituted-4-magnesio-1,2,3-triazoles, revisited. Org Lett (2004) 1.13
Anti-carbohydrate antibodies elicited by polyvalent display on a viral scaffold. Chembiochem (2007) 1.13
A microwave-assisted click chemistry synthesis of 1,4-disubstituted 1,2,3-triazoles via a copper(I)-catalyzed three-component reaction. Org Lett (2004) 1.13
DNA-controlled assembly of a NaTl lattice structure from gold nanoparticles and protein nanoparticles. Nat Mater (2010) 1.11
A nonself sugar mimic of the HIV glycan shield shows enhanced antigenicity. Proc Natl Acad Sci U S A (2010) 1.10
Virus-glycopolymer conjugates by copper(I) catalysis of atom transfer radical polymerization and azide-alkyne cycloaddition. Chem Commun (Camb) (2005) 1.10
Copper-catalyzed reaction cascade: direct conversion of alkynes into N-sulfonylazetidin-2-imines. Angew Chem Int Ed Engl (2006) 1.08
Buckyballs meet viral nanoparticles: candidates for biomedicine. J Am Chem Soc (2009) 1.04
Degradable conjugates from oxanorbornadiene reagents. J Am Chem Soc (2012) 1.03
Inhibitors of VIM-2 by screening pharmacologically active and click-chemistry compound libraries. Bioorg Med Chem (2009) 1.02
A hierarchy of aryloxide deprotection by boron tribromide. Org Lett (2004) 1.01
Oxime-assisted acetylcholinesterase catalytic scavengers of organophosphates that resist aging. J Biol Chem (2011) 1.01
Synthesis of degradable model networks via ATRP and click chemistry. J Am Chem Soc (2006) 1.00
Electrochemically protected copper(I)-catalyzed azide-alkyne cycloaddition. Chembiochem (2008) 0.99
Arylation of rhodium(II) azavinyl carbenes with boronic acids. J Am Chem Soc (2012) 0.99
RNA-directed packaging of enzymes within virus-like particles. Angew Chem Int Ed Engl (2010) 0.99
Generation of candidate ligands for nicotinic acetylcholine receptors via in situ click chemistry with a soluble acetylcholine binding protein template. J Am Chem Soc (2012) 0.99
High sensitivity and analyte capture with desorption/ionization mass spectrometry on silylated porous silicon. Anal Chem (2004) 0.98
Copper-Catalyzed Azide-Alkyne Click Chemistry for Bioconjugation. Curr Protoc Chem Biol (2011) 0.98
Mechanistic studies on the Cu-catalyzed three-component reactions of sulfonyl azides, 1-alkynes and amines, alcohols, or water: dichotomy via a common pathway. J Org Chem (2008) 0.98
Peptide cyclization and cyclodimerization by Cu(I)-mediated azide-alkyne cycloaddition. J Org Chem (2009) 0.97
Cell targeting with hybrid Qβ virus-like particles displaying epidermal growth factor. Chembiochem (2011) 0.97
Synthesis and electrochemistry of 2-ethenyl and 2-ethanyl derivatives of 5-nitroimidazole and antimicrobial activity against Giardia lamblia. J Med Chem (2009) 0.97
Measurement of monovalent and polyvalent carbohydrate-lectin binding by back-scattering interferometry. Anal Chem (2009) 0.96