Consomic rat model systems for physiological genomics.

PubWeight™: 1.50‹?› | Rank: Top 4%

🔗 View Article (PMID 15283774)

Published in Acta Physiol Scand on August 01, 2004

Authors

A W Cowley1, M Liang, R J Roman, A S Greene, H J Jacob

Author Affiliations

1: Department of Physiology, Medical College of Wisconsin, Milwaukee 53226, USA.

Articles citing this

Defining a rat blood pressure quantitative trait locus to a <81.8 kb congenic segment: comprehensive sequencing and renal transcriptome analysis. Physiol Genomics (2010) 1.50

Chromosome substitution reveals the genetic basis of Dahl salt-sensitive hypertension and renal disease. Am J Physiol Renal Physiol (2008) 1.37

Finding the molecular basis of complex genetic variation in humans and mice. Philos Trans R Soc Lond B Biol Sci (2006) 1.06

Dynamic convergence and divergence of renal genomic and biological pathways in protection from Dahl salt-sensitive hypertension. Physiol Genomics (2009) 1.06

High-salt diet and hypertension: focus on the renin-angiotensin system. Kidney Blood Press Res (2010) 1.04

Renal medullary 11 beta-hydroxysteroid dehydrogenase type 1 in Dahl salt-sensitive hypertension. Physiol Genomics (2008) 1.04

Epigenomics of hypertension. Semin Nephrol (2013) 1.00

Genetics of hypertension: from experimental animals to humans. Biochim Biophys Acta (2009) 1.00

The clinical measurement, measurement method and experimental condition ontologies: expansion, improvements and new applications. J Biomed Semantics (2013) 0.96

Role of 20-HETE in the antihypertensive effect of transfer of chromosome 5 from Brown Norway to Dahl salt-sensitive rats. Am J Physiol Regul Integr Comp Physiol (2012) 0.96

Impaired relaxation of cerebral arteries in the absence of elevated salt intake in normotensive congenic rats carrying the Dahl salt-sensitive renin gene. Am J Physiol Heart Circ Physiol (2010) 0.96

Dahl salt-sensitive rats are protected against vascular defects related to diet-induced obesity. Hypertension (2012) 0.95

Online tools for understanding rat physiology. Brief Bioinform (2010) 0.92

The emerging role for rat models in gene discovery. Mamm Genome (2011) 0.89

Role of 20-HETE in the impaired myogenic and TGF responses of the Af-Art of Dahl salt-sensitive rats. Am J Physiol Renal Physiol (2014) 0.87

Role of the CYP4A/20-HETE pathway in vascular dysfunction of the Dahl salt-sensitive rat. Clin Sci (Lond) (2013) 0.86

Characterization of vascular endothelial growth factor receptors on the endothelial cell surface during hypoxia using whole cell binding arrays. Anal Biochem (2007) 0.86

Substitution of Brown Norway chromosome 16 preserves cardiac function with aging in a salt-sensitive Dahl consomic rat. Physiol Genomics (2008) 0.86

Mechanism of differential cardiovascular response to propofol in Dahl salt-sensitive, Brown Norway, and chromosome 13-substituted consomic rat strains: role of large conductance Ca2+ and voltage-activated potassium channels. J Pharmacol Exp Ther (2009) 0.85

Taste solution consumption by FHH-Chr nBN consomic rats. Chem Senses (2010) 0.83

Integrating genomic and clinical medicine: searching for susceptibility genes in complex lung diseases. Transl Res (2007) 0.82

Implication of chromosome 13 on hypertension and associated disorders in Lyon hypertensive rats. J Hypertens (2009) 0.82

Introgression of Brown Norway CYP4A genes on to the Dahl salt-sensitive background restores vascular function in SS-5(BN) consomic rats. Clin Sci (Lond) (2013) 0.82

Physiological genomics analysis for Alzheimer's disease. Ann Indian Acad Neurol (2013) 0.81

Dr Lewis Kitchener Dahl, the Dahl rats, and the "inconvenient truth" about the genetics of hypertension. Hypertension (2015) 0.81

Differences in cardiovascular sensitivity to propofol in a chromosome substitution rat model. Croat Med J (2007) 0.80

Body fat distribution and organ weights of 14 common strains and a 22-strain consomic panel of rats. Physiol Behav (2011) 0.80

Chromosome substitution modulates resistance to ischemia reperfusion injury in Brown Norway rats. Kidney Int (2012) 0.80

Sex-specific differences in chromosome-dependent regulation of vascular reactivity in female consomic rat strains from a SSxBN cross. Am J Physiol Regul Integr Comp Physiol (2008) 0.79

The Mighty Mouse: the impact of rodents on advances in biomedical research. Mo Med (2013) 0.77

Tumor Necrosis Factor α Regulates Endothelial Progenitor Cell Migration via CADM1 and NF-kB. Stem Cells (2016) 0.76

Strain differences in cortical electroencephalogram associated with isoflurane-induced loss of consciousness. Anesthesiology (2013) 0.76

Vascular responses in aortic rings of a consomic rat panel derived from the Fawn Hooded Hypertensive strain. Physiol Genomics (2010) 0.76

Genetically determined mitochondrial preservation and cardioprotection against myocardial ischemia-reperfusion injury in a consomic rat model. Physiol Genomics (2013) 0.75

Physiological genomics analysis for mania: supportive evidence for epigenetics concept. Indian J Psychol Med (2014) 0.75

Pharmacogenomic strain differences in cardiovascular sensitivity to propofol. Anesthesiology (2011) 0.75

p66Shc regulates renal vascular tone in hypertension-induced nephropathy. J Clin Invest (2016) 0.75

Proton channels and renal hypertensive injury: a key piece of the Dahl salt-sensitive rat puzzle? Am J Physiol Regul Integr Comp Physiol (2016) 0.75

Animal models for the study of primary and secondary hypertension in humans. Biomed Rep (2016) 0.75

Articles by these authors

The development and initial validation of the Systemic Lupus International Collaborating Clinics/American College of Rheumatology damage index for systemic lupus erythematosus. Arthritis Rheum (1996) 6.88

Quantitative trait loci on chromosomes 3 and 17 influence phenotypes of the metabolic syndrome. Proc Natl Acad Sci U S A (2000) 3.44

Smurf2 is a ubiquitin E3 ligase mediating proteasome-dependent degradation of Smad2 in transforming growth factor-beta signaling. J Biol Chem (2000) 3.12

A microsatellite genetic linkage map for zebrafish (Danio rerio). Nat Genet (1998) 3.06

Production of 20-HETE and its role in autoregulation of cerebral blood flow. Circ Res (2000) 2.67

Sequence interpretation. Functional annotation of mouse genome sequences. Science (2001) 2.54

A high-density integrated genetic linkage and radiation hybrid map of the laboratory rat. Genome Res (1999) 2.49

Localization of a small genomic region associated with elevated ACE. Am J Hum Genet (2000) 2.13

The future of genetic case-control studies. Adv Genet (2001) 2.11

A genomic-systems biology map for cardiovascular function. Science (2001) 2.09

Brown Norway chromosome 13 confers protection from high salt to consomic Dahl S rat. Hypertension (2001) 1.99

Genetic analysis of non-insulin dependent diabetes mellitus in the GK rat. Nat Genet (1996) 1.96

The genetic basis of plasma variation in adiponectin, a global endophenotype for obesity and the metabolic syndrome. J Clin Endocrinol Metab (2001) 1.82

Mechanism of action of cerebral epoxyeicosatrienoic acids on cerebral arterial smooth muscle. Am J Physiol (1992) 1.80

The role of the kidney in hypertension. JAMA (1996) 1.80

Role of cytochrome P-450 enzymes and metabolites of arachidonic acid in the control of vascular tone. J Vasc Res (1995) 1.76

New target regions for human hypertension via comparative genomics. Genome Res (2000) 1.75

Experimental analysis of the origin of the wing musculature in avian embryos. Anat Embryol (Berl) (1977) 1.73

MR-derived cerebral blood volume maps: issues regarding histological validation and assessment of tumor angiogenesis. Magn Reson Med (2001) 1.68

Molecular characterization of an arachidonic acid epoxygenase in rat brain astrocytes. Stroke (1996) 1.68

Identification and characterization of the CXCR4 chemokine receptor in human T cell lines: ligand binding, biological activity, and HIV-1 infectivity. J Immunol (1998) 1.67

A reference cross DNA panel for zebrafish (Danio rerio) anchored with simple sequence length polymorphisms. Development (1996) 1.67

Genetic dissection of honeybee (Apis mellifera L.) foraging behavior. J Hered (2001) 1.64

Renal disease susceptibility and hypertension are under independent genetic control in the fawn-hooded rat. Nat Genet (1996) 1.61

On the nature of the "non-saturable" migration of amino acids into Ehrlich cells and into rat jejunum. Bibl Laeger (1966) 1.59

Functional hyperemia in the brain: hypothesis for astrocyte-derived vasodilator metabolites. Stroke (1998) 1.58

Fractal morphology, imaging and mass spectrometry of single aerosol particles in flight. Nature (2012) 1.56

Cryptotomography: reconstructing 3D Fourier intensities from randomly oriented single-shot diffraction patterns. Phys Rev Lett (2010) 1.55

Roentgenograms in primary care patients with acute low back pain: a cost-effectiveness analysis. Arch Intern Med (1982) 1.53

Formation and actions of 20-hydroxyeicosatetraenoic acid in rat renal arterioles. Am J Physiol (1996) 1.53

Role of the renal medulla in volume and arterial pressure regulation. Am J Physiol (1997) 1.50

Actions of epoxygenase metabolites on the preglomerular vasculature. J Am Soc Nephrol (1996) 1.50

The use of N-methylation to direct route of mediated transport of amino acids. J Biol Chem (1965) 1.48

20-Hydroxyeicosatetraenoic acid is an endogenous vasoconstrictor of canine renal arcuate arteries. Circ Res (1993) 1.48

Genetic contamination of Dahl SS/Jr rats. Impact on studies of salt-sensitive hypertension. Hypertension (1994) 1.48

The renal medulla and hypertension. Hypertension (1995) 1.46

20-HETE is an endogenous inhibitor of the large-conductance Ca(2+)-activated K+ channel in renal arterioles. Am J Physiol (1996) 1.46

A distinct Na+-requiring transport system for alanine, serine, cysteine, and similar amino acids. J Biol Chem (1967) 1.44

Carotid sinus baroreceptor control of splanchnic resistance and capacity. Am J Physiol (1988) 1.42

Effects of 17-octadecynoic acid, a suicide-substrate inhibitor of cytochrome P450 fatty acid omega-hydroxylase, on renal function in rats. J Pharmacol Exp Ther (1994) 1.38

Endotoxin augments cerebral hyperemic response to halothane by inducing nitric oxide synthase and cyclooxygenase. Anesth Analg (2000) 1.37

20-HETE agonists and antagonists in the renal circulation. Am J Physiol (1999) 1.37

Stereospecific effects of epoxyeicosatrienoic acids on renal vascular tone and K(+)-channel activity. Am J Physiol (1996) 1.33

Primary structure of hepatocyte nuclear factor/forkhead homologue 4 and characterization of gene expression in the developing respiratory and reproductive epithelium. Proc Natl Acad Sci U S A (1995) 1.33

Inhibition of renal vascular 20-HETE production impairs autoregulation of renal blood flow. Am J Physiol (1994) 1.32

Improved mass spectrometric proteomic profiling of the secretome of rat vascular endothelial cells. J Proteome Res (2006) 1.31

Identification of a putative microvascular oxygen sensor. Circ Res (1996) 1.30

EbEST: an automated tool using expressed sequence tags to delineate gene structure. Genome Res (1998) 1.30

Single-particle structure determination by correlations of snapshot X-ray diffraction patterns. Nat Commun (2012) 1.30

Role of nitric oxide in renal papillary blood flow and sodium excretion. Hypertension (1992) 1.26

Opposing actions of angiotensin II on microvascular growth and arterial blood pressure. Hypertension (1996) 1.25

Inhibition of brain P-450 arachidonic acid epoxygenase decreases baseline cerebral blood flow. Am J Physiol (1996) 1.24

Role of tyrosine kinase and PKC in the vasoconstrictor response to 20-HETE in renal arterioles. Hypertension (1999) 1.24

Automated construction of high-density comparative maps between rat, human, and mouse. Genome Res (2001) 1.24

Transport of diamino acids into the Ehrlich cell. J Biol Chem (1966) 1.24

A biometrical genome search in rats reveals the multigenic basis of blood pressure variation. Genome Res (1995) 1.23

Temporary alteration of cerebrovascular permeability to plasma protein during drug-induced seizures. Am J Physiol (1972) 1.21

Evaluation of laser-Doppler flowmetry as a measure of tissue blood flow. J Appl Physiol (1985) (1986) 1.21

Carotid sinus baroreceptor reflex control of respiration. Circ Res (1982) 1.19

Characterization of a new model for the study of pressure-natriuresis in the rat. Am J Physiol (1985) 1.19

Chronic inhalation of nitric oxide inhibits neointimal formation after balloon-induced arterial injury. Circ Res (1996) 1.19

Anti-inflammatory and safety profile of DuP 697, a novel orally effective prostaglandin synthesis inhibitor. J Pharmacol Exp Ther (1990) 1.19

Angiotensin II and VEGF are involved in angiogenesis induced by short-term exercise training. Am J Physiol Heart Circ Physiol (2001) 1.18

Inhibition of 20-HETE production contributes to the vascular responses to nitric oxide. Hypertension (1997) 1.18

Role of 20-HETE in elevating chloride transport in the thick ascending limb of Dahl SS/Jr rats. Hypertension (1999) 1.17

Altered renal hemodynamics and impaired myogenic responses in the fawn-hooded rat. Am J Physiol (1999) 1.17

Waist circumference, body mass index and waist to hip ratio for prediction of the metabolic syndrome in Chinese. Nutr Metab Cardiovasc Dis (2009) 1.16

Suppression of angiotensin-converting enzyme expression and activity by shear stress. Circ Res (1997) 1.16

Effect of P-450 omega-hydroxylase metabolites of arachidonic acid on tubuloglomerular feedback. Am J Physiol (1994) 1.16

Resistance to myocardial ischemia in five rat strains: is there a genetic component of cardioprotection? Am J Physiol Heart Circ Physiol (2000) 1.15

Angiogenesis induced by electrical stimulation is mediated by angiotensin II and VEGF. Microcirculation (2001) 1.15

Localization of cytochrome P-450 4A isoforms along the rat nephron. Am J Physiol (1998) 1.12

Nitric oxide-20-hydroxyeicosatetraenoic acid interaction in the regulation of K+ channel activity and vascular tone in renal arterioles. Circ Res (1998) 1.12

Contribution of 20-HETE to the vasodilator actions of nitric oxide in renal arteries. Am J Physiol (1998) 1.11

Renin gene transfer restores angiogenesis and vascular endothelial growth factor expression in Dahl S rats. Hypertension (2001) 1.11

Abnormal renal hemodynamics and pressure-natriuresis relationship in Dahl salt-sensitive rats. Am J Physiol (1986) 1.09

Role of cytochrome P450 metabolites of arachidonic acid in hypertension. Curr Drug Metab (2004) 1.09

Role of blood volume expansion in Dahl rat model of hypertension. Am J Physiol (1990) 1.09

Defensive peripersonal space: the blink reflex evoked by hand stimulation is increased when the hand is near the face. J Neurophysiol (2011) 1.09

Cytochrome P450 metabolites of arachidonic acid as intracellular signaling molecules in vascular tissue. J Vasc Res (1997) 1.08

Use of AFLP markers for gene mapping and QTL detection in the rat. Genomics (1996) 1.07

Localization of the ANG II type 2 receptor in the microcirculation of skeletal muscle. Am J Physiol (1998) 1.07

Evidence of gene-gene interactions in the genetic susceptibility to renal impairment after unilateral nephrectomy. J Am Soc Nephrol (2000) 1.07

Lack of association between a biallelic polymorphism in the adducin gene and blood pressure in whites and African Americans. Am J Hypertens (2000) 1.07

Altered renal P-450 metabolism of arachidonic acid in Dahl salt-sensitive rats. Am J Physiol (1994) 1.06

Coexistence of two types of Ca(2+)-activated K+ channels in rat renal arterioles. Am J Physiol (1996) 1.06

On the origin and development of the ventrolateral abdominal muscles in the avian embryo. An experimental and ultrastructural study. Anat Embryol (Berl) (1983) 1.06

Discriminative analysis of brain function at resting-state for attention-deficit/hyperactivity disorder. Med Image Comput Comput Assist Interv (2005) 1.06

Regional cerebral blood flow responses to variable frequency whisker stimulation: an autoradiographic analysis. Brain Res (2000) 1.05

Regulation of P-450 4A activity in the glomerulus of the rat. Am J Physiol (1999) 1.04

Fluorometric assay for urea in urine, plasma, and tubular fluid. Anal Biochem (1979) 1.04

Impaired autoregulation of renal blood flow in the fawn-hooded rat. Am J Physiol (1999) 1.04