Published in Mol Endocrinol on August 12, 2004
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Dual role of FoxA1 in androgen receptor binding to chromatin, androgen signalling and prostate cancer. EMBO J (2011) 2.55
Phosphorylation of histone H3T6 by PKCbeta(I) controls demethylation at histone H3K4. Nature (2010) 2.01
Androgen receptor functions in castration-resistant prostate cancer and mechanisms of resistance to new agents targeting the androgen axis. Oncogene (2013) 1.86
Androgen receptor phosphorylation and stabilization in prostate cancer by cyclin-dependent kinase 1. Proc Natl Acad Sci U S A (2006) 1.75
The cell fate determination factor dachshund inhibits androgen receptor signaling and prostate cancer cellular growth. Cancer Res (2009) 1.58
Sirtuin 1 is required for antagonist-induced transcriptional repression of androgen-responsive genes by the androgen receptor. Mol Endocrinol (2007) 1.43
Peroxisome proliferator-activated receptor subtype- and cell-type-specific activation of genomic target genes upon adenoviral transgene delivery. Mol Cell Biol (2006) 1.43
Non-competitive androgen receptor inhibition in vitro and in vivo. Proc Natl Acad Sci U S A (2009) 1.37
MUC1 oncoprotein is a druggable target in human prostate cancer cells. Mol Cancer Ther (2009) 1.30
Deleted in breast cancer 1, a novel androgen receptor (AR) coactivator that promotes AR DNA-binding activity. J Biol Chem (2009) 1.30
Long-range activation of FKBP51 transcription by the androgen receptor via distal intronic enhancers. Nucleic Acids Res (2009) 1.26
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Regulation of the androgen receptor by SET9-mediated methylation. Nucleic Acids Res (2010) 1.17
Androgen receptor functional analyses by high throughput imaging: determination of ligand, cell cycle, and mutation-specific effects. PLoS One (2008) 1.13
Epigenetic control of a VDR-governed feed-forward loop that regulates p21(waf1/cip1) expression and function in non-malignant prostate cells. Nucleic Acids Res (2010) 1.03
Structural basis for nuclear receptor corepressor recruitment by antagonist-liganded androgen receptor. Mol Cancer Ther (2008) 0.99
Receptor-interacting protein 140 is a repressor of the androgen receptor activity. Mol Endocrinol (2006) 0.99
Histone modifications and chromatin organization in prostate cancer. Epigenomics (2010) 0.99
NFI transcription factors interact with FOXA1 to regulate prostate-specific gene expression. Mol Endocrinol (2014) 0.96
A novel androgen receptor-binding element modulates Cdc6 transcription in prostate cancer cells during cell-cycle progression. Nucleic Acids Res (2009) 0.95
Small carboxyl-terminal domain phosphatase 2 attenuates androgen-dependent transcription. EMBO J (2006) 0.94
Identification of a novel inhibitor of coactivator-associated arginine methyltransferase 1 (CARM1)-mediated methylation of histone H3 Arg-17. J Biol Chem (2009) 0.93
Cyclin D1 is a selective modifier of androgen-dependent signaling and androgen receptor function. J Biol Chem (2011) 0.92
Tissue-specific pioneer factors associate with androgen receptor cistromes and transcription programs. EMBO J (2014) 0.92
Redefining hormone resistance in prostate cancer. Ther Adv Med Oncol (2010) 0.91
Recruitment of NCOR1 to VDR target genes is enhanced in prostate cancer cells and associates with altered DNA methylation patterns. Carcinogenesis (2012) 0.91
CCAR1 promotes chromatin loading of androgen receptor (AR) transcription complex by stabilizing the association between AR and GATA2. Nucleic Acids Res (2013) 0.89
A competitive inhibitor that reduces recruitment of androgen receptor to androgen-responsive genes. J Biol Chem (2012) 0.88
Reducing prohibitin increases histone acetylation, and promotes androgen independence in prostate tumours by increasing androgen receptor activation by adrenal androgens. Oncogene (2011) 0.86
Differential alterations in gene expression profiles contribute to time-dependent effects of nandrolone to prevent denervation atrophy. BMC Genomics (2010) 0.85
Altered TNSALP expression and phosphate regulation contribute to reduced mineralization in mice lacking androgen receptor. Mol Cell Biol (2008) 0.85
Biochemical characterization of androgen receptor-interacting protein 4. Biochem J (2006) 0.82
Therapeutic Rationales, Progresses, Failures, and Future Directions for Advanced Prostate Cancer. Int J Biol Sci (2016) 0.81
Androgen receptor inclusions acquire GRP78/BiP to ameliorate androgen-induced protein misfolding stress in embryonic stem cells. Cell Death Dis (2013) 0.81
Androgen receptor uses relaxed response element stringency for selective chromatin binding and transcriptional regulation in vivo. Nucleic Acids Res (2014) 0.81
NBBS isolated from Pygeum africanum bark exhibits androgen antagonistic activity, inhibits AR nuclear translocation and prostate cancer cell growth. Invest New Drugs (2009) 0.81
Transgelin induces apoptosis of human prostate LNCaP cells through its interaction with p53. Asian J Androl (2010) 0.81
The expanding role for chromatin and transcription in polyglutamine disease. Curr Opin Genet Dev (2014) 0.81
Androgen receptor signalling in prostate cancer: the functional consequences of acetylation. J Biomed Biotechnol (2010) 0.80
New insights into the androgen-targeted therapies and epigenetic therapies in prostate cancer. Prostate Cancer (2011) 0.79
CK2-NCoR signaling cascade promotes prostate tumorigenesis. Oncotarget (2013) 0.79
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Supraphysiological androgen levels induce cellular senescence in human prostate cancer cells through the Src-Akt pathway. Mol Cancer (2014) 0.78
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Influence of short polyglutamine tracts and p160 coactivators on the transactivation of the androgen receptor. Cancer Biother Radiopharm (2011) 0.77
Transcription factors involved in prostate gland adaptation to androgen deprivation. PLoS One (2014) 0.77
VDR regulation of microRNA differs across prostate cell models suggesting extremely flexible control of transcription. Epigenetics (2015) 0.77
Research Resource: Androgen Receptor Activity Is Regulated Through the Mobilization of Cell Surface Receptor Networks. Mol Endocrinol (2015) 0.76
Registered report: the androgen receptor induces a distinct transcriptional program in castration-resistant prostate cancer in man. PeerJ (2015) 0.75
Small-molecule hormones: molecular mechanisms of action. Int J Endocrinol (2013) 0.75
Inhibition of Androgen Receptor Nuclear Localization and Castration Resistant Prostate Tumor Growth by Pyrroloimidazole-Based Small Molecules. Mol Cancer Ther (2017) 0.75
Androgen receptor regulates a distinct transcription program in androgen-independent prostate cancer. Cell (2009) 7.09
A hierarchical network of transcription factors governs androgen receptor-dependent prostate cancer growth. Mol Cell (2007) 5.99
RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation. Nat Cell Biol (2008) 5.90
PIAS proteins modulate transcription factors by functioning as SUMO-1 ligases. Mol Cell Biol (2002) 3.25
PDSM, a motif for phosphorylation-dependent SUMO modification. Proc Natl Acad Sci U S A (2005) 3.01
Dual role of FoxA1 in androgen receptor binding to chromatin, androgen signalling and prostate cancer. EMBO J (2011) 2.55
Circadian clock control by SUMOylation of BMAL1. Science (2005) 2.30
Phosphorylation of serine 303 is a prerequisite for the stress-inducible SUMO modification of heat shock factor 1. Mol Cell Biol (2003) 2.17
PIAS proteins: pleiotropic interactors associated with SUMO. Cell Mol Life Sci (2009) 1.94
Involvement of proteasome in the dynamic assembly of the androgen receptor transcription complex. J Biol Chem (2002) 1.90
Acetylation of androgen receptor enhances coactivator binding and promotes prostate cancer cell growth. Mol Cell Biol (2003) 1.89
FoxA1 specifies unique androgen and glucocorticoid receptor binding events in prostate cancer cells. Cancer Res (2012) 1.72
The nuclear receptor interaction domain of GRIP1 is modulated by covalent attachment of SUMO-1. J Biol Chem (2002) 1.57
Increased expression of androgen receptor sensitizes prostate cancer cells to low levels of androgens. Cancer Res (2009) 1.54
A two-base deletion -439delGC in the melanocortin-4 receptor promoter associated with early-onset obesity. Horm Res (2006) 1.52
GPS2-dependent corepressor/SUMO pathways govern anti-inflammatory actions of LRH-1 and LXRbeta in the hepatic acute phase response. Genes Dev (2010) 1.52
Androgen receptor acetylation governs trans activation and MEKK1-induced apoptosis without affecting in vitro sumoylation and trans-repression function. Mol Cell Biol (2002) 1.48
Identification of glucocorticoid-response genes in children with acute lymphoblastic leukemia. Blood (2005) 1.46
Sumo-1 function is dispensable in normal mouse development. Mol Cell Biol (2008) 1.37
Small ubiquitin-related modifier-1 (SUMO-1) modification of the glucocorticoid receptor. Biochem J (2002) 1.33
SUMO-specific protease 1 (SENP1) reverses the hormone-augmented SUMOylation of androgen receptor and modulates gene responses in prostate cancer cells. Mol Endocrinol (2008) 1.32
Glucocorticoid receptor activates poised FKBP51 locus through long-distance interactions. Mol Endocrinol (2010) 1.31
PIAS proteins promote SUMO-1 conjugation to STAT1. Blood (2003) 1.29
hZimp10 is an androgen receptor co-activator and forms a complex with SUMO-1 at replication foci. EMBO J (2003) 1.28
Long-range activation of FKBP51 transcription by the androgen receptor via distal intronic enhancers. Nucleic Acids Res (2009) 1.26
Inhibition of androgen receptor (AR) function by the reproductive orphan nuclear receptor DAX-1. Mol Endocrinol (2002) 1.23
SUMO-1 promotes association of SNURF (RNF4) with PML nuclear bodies. Exp Cell Res (2004) 1.21
Identification of a hormone-regulated dynamic nuclear actin network associated with estrogen receptor alpha in human breast cancer cell nuclei. Mol Cell Proteomics (2010) 1.19
SUMO-1 conjugation selectively modulates STAT1-mediated gene responses. Blood (2005) 1.18
Expression of androgen receptor coregulators in prostate cancer. Clin Cancer Res (2004) 1.17
SUMOylation attenuates the function of PGC-1alpha. J Biol Chem (2009) 1.14
Steroid up-regulation of FKBP51 and its role in hormone signaling. Curr Opin Pharmacol (2011) 1.12
Pattern of somatic androgen receptor gene mutations in patients with hormone-refractory prostate cancer. Lab Invest (2002) 1.06
TRIM37 defective in mulibrey nanism is a novel RING finger ubiquitin E3 ligase. Exp Cell Res (2005) 1.05
Dynamic SUMOylation is linked to the activity cycles of androgen receptor in the cell nucleus. Mol Cell Biol (2012) 1.04
Androgen receptor-interacting protein 3 and other PIAS proteins cooperate with glucocorticoid receptor-interacting protein 1 in steroid receptor-dependent signaling. J Biol Chem (2002) 1.04
SUMOylation modulates the transcription repressor function of RIP140. J Biol Chem (2008) 1.02
Effects of triaryl phosphates on mouse and human nuclear receptors. Biochem Pharmacol (2004) 1.00
ZNF451 is a novel PML body- and SUMO-associated transcriptional coregulator. J Mol Biol (2008) 0.96
SUMOylation regulates the chromatin occupancy and anti-proliferative gene programs of glucocorticoid receptor. Nucleic Acids Res (2013) 0.96
Proto-oncogene PIM-1 is a novel estrogen receptor target associating with high grade breast tumors. Mol Cell Endocrinol (2012) 0.96
Androgen receptor amplification is reflected in the transcriptional responses of Vertebral-Cancer of the Prostate cells. Mol Cell Endocrinol (2010) 0.95
Small carboxyl-terminal domain phosphatase 2 attenuates androgen-dependent transcription. EMBO J (2006) 0.94
Tissue-specific pioneer factors associate with androgen receptor cistromes and transcription programs. EMBO J (2014) 0.92
Transcriptional regulation of the ornithine decarboxylase gene by c-Myc/Max/Mad network and retinoblastoma protein interacting with c-Myc. Int J Biochem Cell Biol (2003) 0.91
KIT overexpression induces proliferation in astrocytes in an imatinib-responsive manner and associates with proliferation index in gliomas. Int J Cancer (2008) 0.91
Inhibition of small ubiquitin-related modifier-1 expression by luteinizing hormone receptor stimulation is linked to induction of progesterone receptor during ovulation in mouse granulosa cells. Endocrinology (2003) 0.91
Novel ATPase of SNF2-like protein family interacts with androgen receptor and modulates androgen-dependent transcription. Mol Biol Cell (2002) 0.91
Androgen receptor and androgen-dependent gene expression in lung. Mol Cell Endocrinol (2009) 0.90
Functional interaction of AIRE with PIAS1 in transcriptional regulation. Mol Immunol (2008) 0.89
Androgen receptor mutations in high-grade prostate cancer before hormonal therapy. Lab Invest (2003) 0.89
Down-regulation of estrogen receptor beta and transcriptional coregulator SNURF/RNF4 in testicular germ cell cancer. Eur Urol (2003) 0.89
SUMOylation can regulate the activity of ETS-like transcription factor 4. Biochim Biophys Acta (2010) 0.88
Histone H2B ubiquitin ligases RNF20 and RNF40 in androgen signaling and prostate cancer cell growth. Mol Cell Endocrinol (2011) 0.88
Interleukins 1α and 1β as regulators of steroidogenesis in human NCI-H295R adrenocortical cells. Steroids (2011) 0.87
Small nuclear RING finger protein stimulates the rat luteinizing hormone-beta promoter by interacting with Sp1 and steroidogenic factor-1 and protects from androgen suppression. Mol Endocrinol (2004) 0.87
Cooperative coactivation of estrogen receptor alpha in ZR-75 human breast cancer cells by SNURF and TATA-binding protein. J Biol Chem (2001) 0.87
Attenuation of androgen receptor-dependent transcription by the serine/threonine kinase Pim-1. Lab Invest (2003) 0.87
Protein inhibitor of activated STAT3 (PIAS3) protein promotes SUMOylation and nuclear sequestration of the intracellular domain of ErbB4 protein. J Biol Chem (2012) 0.87
Prostaglandin 15d-PGJ(2) inhibits androgen receptor signaling in prostate cancer cells. Mol Endocrinol (2012) 0.86
Expression of the E3 SUMO-1 ligases PIASx and PIAS1 during spermatogenesis in the rat. Gene Expr Patterns (2003) 0.86
Serum androgen bioactivity in cryptorchid and noncryptorchid boys during the postnatal reproductive hormone surge. J Clin Endocrinol Metab (2003) 0.85
Histone demethylase GASC1--a potential prognostic and predictive marker in invasive breast cancer. BMC Cancer (2012) 0.84
PQBP-1 transgenic mice show a late-onset motor neuron disease-like phenotype. Hum Mol Genet (2003) 0.84
Nuclear mobility and activity of FOXA1 with androgen receptor are regulated by SUMOylation. Mol Endocrinol (2014) 0.83
Circulating glucocorticoid bioactivity during peroral glucocorticoid treatment in children and adolescents with inflammatory bowel disease. J Clin Gastroenterol (2008) 0.83
Androgen receptor regulates nuclear trafficking and nuclear domain residency of corepressor HDAC7 in a ligand-dependent fashion. Exp Cell Res (2006) 0.83
Genomic region operation kit for flexible processing of deep sequencing data. IEEE/ACM Trans Comput Biol Bioinform (2013) 0.82
Biochemical characterization of androgen receptor-interacting protein 4. Biochem J (2006) 0.82
Oestrogen receptors and small nuclear ring finger protein 4 (RNF4) in malignant ovarian germ cell tumours. Mol Cell Endocrinol (2009) 0.82
TWIST overexpression predicts biochemical recurrence-free survival in prostate cancer patients treated with radical prostatectomy. Scand J Urol (2014) 0.82
Transactivation assay for determination of glucocorticoid bioactivity in human serum. J Clin Endocrinol Metab (2002) 0.81
Expression of the nuclear RING finger protein SNURF/RNF4 during rat testis development suggests a role in spermatid maturation. Mech Dev (2002) 0.81
FLI-1 functionally interacts with PIASxalpha, a member of the PIAS E3 SUMO ligase family. J Biol Chem (2005) 0.81
Analysis of androgen receptor SUMOylation. Methods Mol Biol (2011) 0.81
Androgen receptor uses relaxed response element stringency for selective chromatin binding and transcriptional regulation in vivo. Nucleic Acids Res (2014) 0.81