Published in Mol Cell on August 27, 2004
Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair. Cell (2007) 6.68
Maintaining genome stability at the replication fork. Nat Rev Mol Cell Biol (2010) 5.88
How the fanconi anemia pathway guards the genome. Annu Rev Genet (2009) 4.94
The Fanconi anemia pathway promotes replication-dependent DNA interstrand cross-link repair. Science (2009) 4.85
Mechanism of replication-coupled DNA interstrand crosslink repair. Cell (2008) 4.53
Human Fanconi anemia monoubiquitination pathway promotes homologous DNA repair. Proc Natl Acad Sci U S A (2005) 3.93
Fancd2 counteracts the toxic effects of naturally produced aldehydes in mice. Nature (2011) 3.79
Eukaryotic translesion polymerases and their roles and regulation in DNA damage tolerance. Microbiol Mol Biol Rev (2009) 3.62
A genetic screen identifies FAN1, a Fanconi anemia-associated nuclease necessary for DNA interstrand crosslink repair. Mol Cell (2010) 3.51
Regulation of DNA cross-link repair by the Fanconi anemia/BRCA pathway. Genes Dev (2012) 3.42
Expanded roles of the Fanconi anemia pathway in preserving genomic stability. Genes Dev (2010) 3.33
Yeast Mph1 helicase dissociates Rad51-made D-loops: implications for crossover control in mitotic recombination. Genes Dev (2009) 2.43
Maternal aldehyde elimination during pregnancy preserves the fetal genome. Mol Cell (2014) 2.24
Remodeling of DNA replication structures by the branch point translocase FANCM. Proc Natl Acad Sci U S A (2008) 2.20
Inactivation of murine Usp1 results in genomic instability and a Fanconi anemia phenotype. Dev Cell (2009) 2.12
Deubiquitination of FANCD2 is required for DNA crosslink repair. Mol Cell (2007) 2.11
Mechanism of RAD51-dependent DNA interstrand cross-link repair. Science (2011) 2.04
FAAP100 is essential for activation of the Fanconi anemia-associated DNA damage response pathway. EMBO J (2007) 2.00
A selective USP1-UAF1 inhibitor links deubiquitination to DNA damage responses. Nat Chem Biol (2014) 1.86
Fanconi anemia proteins are required to prevent accumulation of replication-associated DNA double-strand breaks. Mol Cell Biol (2006) 1.82
DNA interstrand crosslink repair in mammalian cells: step by step. Crit Rev Biochem Mol Biol (2010) 1.82
Fanconi anemia pathway-deficient tumor cells are hypersensitive to inhibition of ataxia telangiectasia mutated. J Clin Invest (2007) 1.80
Cellular and molecular consequences of defective Fanconi anemia proteins in replication-coupled DNA repair: mechanistic insights. Mutat Res (2009) 1.80
Molecular pathogenesis and clinical management of Fanconi anemia. J Clin Invest (2012) 1.79
The Fanconi anemia core complex is required for efficient point mutagenesis and Rev1 foci assembly. DNA Repair (Amst) (2008) 1.74
Regulation of Rev1 by the Fanconi anemia core complex. Nat Struct Mol Biol (2012) 1.72
Hypomorphic mutations in the gene encoding a key Fanconi anemia protein, FANCD2, sustain a significant group of FA-D2 patients with severe phenotype. Am J Hum Genet (2007) 1.67
Histone H2AX and Fanconi anemia FANCD2 function in the same pathway to maintain chromosome stability. EMBO J (2007) 1.65
The Walker B motif in avian FANCM is required to limit sister chromatid exchanges but is dispensable for DNA crosslink repair. Nucleic Acids Res (2009) 1.65
TopBP1 interacts with BLM to maintain genome stability but is dispensable for preventing BLM degradation. Mol Cell (2015) 1.60
The Fanconi Anemia Pathway Maintains Genome Stability by Coordinating Replication and Transcription. Mol Cell (2015) 1.59
Functional relationships of FANCC to homologous recombination, translesion synthesis, and BLM. EMBO J (2004) 1.56
Differential roles for DNA polymerases eta, zeta, and REV1 in lesion bypass of intrastrand versus interstrand DNA cross-links. Mol Cell Biol (2009) 1.54
Minding the gap: the underground functions of BRCA1 and BRCA2 at stalled replication forks. DNA Repair (Amst) (2007) 1.52
Lysine 63-polyubiquitination guards against translesion synthesis-induced mutations. PLoS Genet (2006) 1.50
XPF-ERCC1 participates in the Fanconi anemia pathway of cross-link repair. Mol Cell Biol (2009) 1.50
DNA polymerase POLN participates in cross-link repair and homologous recombination. Mol Cell Biol (2009) 1.47
FANCJ coordinates two pathways that maintain epigenetic stability at G-quadruplex DNA. Nucleic Acids Res (2011) 1.45
Advances in understanding the complex mechanisms of DNA interstrand cross-link repair. Cold Spring Harb Perspect Biol (2013) 1.45
UBE2T, the Fanconi anemia core complex, and FANCD2 are recruited independently to chromatin: a basis for the regulation of FANCD2 monoubiquitination. Mol Cell Biol (2007) 1.40
Mouse SLX4 is a tumor suppressor that stimulates the activity of the nuclease XPF-ERCC1 in DNA crosslink repair. Mol Cell (2014) 1.34
DNA damage tolerance: a double-edged sword guarding the genome. Transl Cancer Res (2013) 1.33
Rad18-mediated translesion synthesis of bulky DNA adducts is coupled to activation of the Fanconi anemia DNA repair pathway. J Biol Chem (2010) 1.32
RTEL1 contributes to DNA replication and repair and telomere maintenance. Mol Biol Cell (2012) 1.28
Double-strand breaks induce homologous recombinational repair of interstrand cross-links via cooperation of MSH2, ERCC1-XPF, REV3, and the Fanconi anemia pathway. DNA Repair (Amst) (2007) 1.26
KIAA1018/FAN1 nuclease protects cells against genomic instability induced by interstrand cross-linking agents. Proc Natl Acad Sci U S A (2010) 1.25
Targeting the Fanconi anemia/BRCA pathway circumvents drug resistance in multiple myeloma. Cancer Res (2009) 1.25
Functional interaction between the Fanconi Anemia D2 protein and proliferating cell nuclear antigen (PCNA) via a conserved putative PCNA interaction motif. J Biol Chem (2009) 1.22
The genetic and biochemical basis of FANCD2 monoubiquitination. Mol Cell (2014) 1.22
Ubiquitylation and the Fanconi anemia pathway. FEBS Lett (2011) 1.21
Two modules in the BRC repeats of BRCA2 mediate structural and functional interactions with the RAD51 recombinase. Nucleic Acids Res (2009) 1.21
Xpf and not the Fanconi anaemia proteins or Rev3 accounts for the extreme resistance to cisplatin in Dictyostelium discoideum. PLoS Genet (2009) 1.19
Coordinate regulation of Fanconi anemia gene expression occurs through the Rb/E2F pathway. Oncogene (2008) 1.18
Recruitment of DNA polymerase eta by FANCD2 in the early response to DNA damage. Cell Cycle (2013) 1.17
BRCA1 promotes unloading of the CMG helicase from a stalled DNA replication fork. Mol Cell (2014) 1.14
Chromatin structure regulates gene conversion. PLoS Biol (2007) 1.12
Using synthetic DNA interstrand crosslinks to elucidate repair pathways and identify new therapeutic targets for cancer chemotherapy. Cell Mol Life Sci (2010) 1.12
Fanconi anemia proteins and endogenous stresses. Mutat Res (2009) 1.11
The Fanconi anemia pathway and ubiquitin. BMC Biochem (2007) 1.10
Targeting the FANCJ-BRCA1 interaction promotes a switch from recombination to poleta-dependent bypass. Oncogene (2010) 1.10
Translesion DNA synthesis and mutagenesis in eukaryotes. Cold Spring Harb Perspect Biol (2013) 1.09
Targeting and processing of site-specific DNA interstrand crosslinks. Environ Mol Mutagen (2010) 1.05
Unconventional ubiquitin recognition by the ubiquitin-binding motif within the Y family DNA polymerases iota and Rev1. Mol Cell (2010) 1.05
RAD51C: a novel cancer susceptibility gene is linked to Fanconi anemia and breast cancer. Carcinogenesis (2010) 1.02
Rescue of replication failure by Fanconi anaemia proteins. Chromosoma (2011) 1.02
Fanconi anemia and Bloom's syndrome crosstalk through FANCJ-BLM helicase interaction. Trends Genet (2011) 1.00
Fanconi anemia proteins, DNA interstrand crosslink repair pathways, and cancer therapy. Curr Cancer Drug Targets (2009) 1.00
Characterization of the human SNM1A and SNM1B/Apollo DNA repair exonucleases. J Biol Chem (2012) 1.00
Repair of DNA interstrand cross-links during S phase of the mammalian cell cycle. Environ Mol Mutagen (2010) 0.99
The roles of DNA polymerase ζ and the Y family DNA polymerases in promoting or preventing genome instability. Mutat Res (2012) 0.99
Structure-dependent bypass of DNA interstrand crosslinks by translesion synthesis polymerases. Nucleic Acids Res (2011) 0.98
Age-dependent accumulation of recombinant cells in the mouse pancreas revealed by in situ fluorescence imaging. Proc Natl Acad Sci U S A (2006) 0.97
The BLM dissolvasome in DNA replication and repair. Cell Mol Life Sci (2013) 0.97
High-resolution sex-specific linkage maps of the mouse reveal polarized distribution of crossovers in male germline. Genetics (2014) 0.97
Targeted gene therapy and cell reprogramming in Fanconi anemia. EMBO Mol Med (2014) 0.95
Rad5-dependent DNA repair functions of the Saccharomyces cerevisiae FANCM protein homolog Mph1. J Biol Chem (2012) 0.95
Disparate contributions of the Fanconi anemia pathway and homologous recombination in preventing spontaneous mutagenesis. Nucleic Acids Res (2007) 0.93
Components of a Fanconi-like pathway control Pso2-independent DNA interstrand crosslink repair in yeast. PLoS Genet (2012) 0.93
Regulation of the Rev1-pol ζ complex during bypass of a DNA interstrand cross-link. EMBO J (2015) 0.93
Regulation and roles of Cdc7 kinase under replication stress. Cell Cycle (2014) 0.92
Functional connection between Rad51 and PML in homology-directed repair. PLoS One (2011) 0.92
The Fanconi anaemia components UBE2T and FANCM are functionally linked to nucleotide excision repair. PLoS One (2012) 0.91
The Fanconi anemia pathway and ICL repair: implications for cancer therapy. Crit Rev Biochem Mol Biol (2010) 0.90
The differences between ICL repair during and outside of S phase. Trends Biochem Sci (2013) 0.88
Brca1 in immunoglobulin gene conversion and somatic hypermutation. DNA Repair (Amst) (2007) 0.88
DNA polymerase ζ is a major determinant of resistance to platinum-based chemotherapeutic agents. Mol Pharmacol (2012) 0.88
FANCD1/BRCA2 plays predominant role in the repair of DNA damage induced by ACNU or TMZ. PLoS One (2011) 0.87
FANCC suppresses short telomere-initiated telomere sister chromatid exchange. Hum Mol Genet (2009) 0.87
FANCD2 hurdles the DNA interstrand crosslink. Cell (2009) 0.86
Snm1B/Apollo functions in the Fanconi anemia pathway in response to DNA interstrand crosslinks. Hum Mol Genet (2011) 0.86
CtIP is required to initiate replication-dependent interstrand crosslink repair. PLoS Genet (2012) 0.86
A concomitant loss of dormant origins and FANCC exacerbates genome instability by impairing DNA replication fork progression. Nucleic Acids Res (2014) 0.85
Defects in DNA lesion bypass lead to spontaneous chromosomal rearrangements and increased cell death. Eukaryot Cell (2009) 0.84
E3 ubiquitin ligase HOIP attenuates apoptotic cell death induced by cisplatin. Cancer Res (2014) 0.84
Genomic instability in mice is greater in Fanconi anemia caused by deficiency of Fancd2 than Fancg. Cancer Res (2010) 0.84
p53 null fluorescent yellow direct repeat (FYDR) mice have normal levels of homologous recombination. DNA Repair (Amst) (2011) 0.84
Genetic variation stimulated by epigenetic modification. PLoS One (2008) 0.83
The Fanconi anemia pathway and DNA interstrand cross-link repair. Protein Cell (2011) 0.83
MEN1 and FANCD2 mediate distinct mechanisms of DNA crosslink repair. DNA Repair (Amst) (2008) 0.82
Functions and regulation of the multitasking FANCM family of DNA motor proteins. Genes Dev (2015) 0.82
Fancd2 counteracts the toxic effects of naturally produced aldehydes in mice. Nature (2011) 3.79
Transcatheter valve-in-valve implantation for failed bioprosthetic heart valves. Circulation (2010) 3.65
Genotoxic consequences of endogenous aldehydes on mouse haematopoietic stem cell function. Nature (2012) 3.34
Extreme diving of beaked whales. J Exp Biol (2006) 2.95
A prospective, randomized, multicenter trial of amnioreduction vs selective fetoscopic laser photocoagulation for the treatment of severe twin-twin transfusion syndrome. Am J Obstet Gynecol (2007) 2.73
Disruption of mouse Slx4, a regulator of structure-specific nucleases, phenocopies Fanconi anemia. Nat Genet (2011) 2.72
Ku70 corrupts DNA repair in the absence of the Fanconi anemia pathway. Science (2010) 2.67
The vertebrate Hef ortholog is a component of the Fanconi anemia tumor-suppressor pathway. Nat Struct Mol Biol (2005) 2.55
Lung cancer screening with sputum cytologic examination, chest radiography, and computed tomography: an update for the U.S. Preventive Services Task Force. Ann Intern Med (2004) 2.53
Mechanistic insight into site-restricted monoubiquitination of FANCD2 by Ube2t, FANCL, and FANCI. Mol Cell (2008) 2.45
Deep-diving foraging behaviour of sperm whales (Physeter macrocephalus). J Anim Ecol (2006) 2.41
The NIH genetic testing registry: a new, centralized database of genetic tests to enable access to comprehensive information and improve transparency. Nucleic Acids Res (2012) 2.35
Identification of a gene expression signature associated with recurrent disease in squamous cell carcinoma of the head and neck. Cancer Res (2004) 2.35
A double-blind randomized controlled clinical trial to assess the effect of Doppler optimized intraoperative fluid management on outcome following radical cystectomy. J Urol (2011) 2.19
Deubiquitination of FANCD2 is required for DNA crosslink repair. Mol Cell (2007) 2.11
Mapping infant brain myelination with magnetic resonance imaging. J Neurosci (2011) 1.97
Formaldehyde catabolism is essential in cells deficient for the Fanconi anemia DNA-repair pathway. Nat Struct Mol Biol (2011) 1.95
Interaction between the helicases genetically linked to Fanconi anemia group J and Bloom's syndrome. EMBO J (2011) 1.95
Established human papillomavirus type 16-expressing tumors are effectively eradicated following vaccination with long peptides. J Immunol (2002) 1.93
FANCJ is a structure-specific DNA helicase associated with the maintenance of genomic G/C tracts. J Biol Chem (2008) 1.93
Control of spin precession in a spin-injected field effect transistor. Science (2009) 1.93
Ocular biomechanics and biotransport. Annu Rev Biomed Eng (2004) 1.91
Reducing DUI among US college students: results of an environmental prevention trial. Addiction (2005) 1.87
Mechanisms and treatment of cardiovascular disease in Williams-Beuren syndrome. J Clin Invest (2008) 1.86
Cystic adenomatoid malformation volume ratio predicts outcome in prenatally diagnosed cystic adenomatoid malformation of the lung. J Pediatr Surg (2002) 1.84
Aging, age-related macular degeneration, and the response-to-retention of apolipoprotein B-containing lipoproteins. Prog Retin Eye Res (2009) 1.80
The changing paradigm of outflow resistance generation: towards synergistic models of the JCT and inner wall endothelium. Exp Eye Res (2008) 1.77
The Fanconi anaemia pathway orchestrates incisions at sites of crosslinked DNA. J Pathol (2011) 1.68
The Walker B motif in avian FANCM is required to limit sister chromatid exchanges but is dispensable for DNA crosslink repair. Nucleic Acids Res (2009) 1.65
The oil spill in ageing Bruch membrane. Br J Ophthalmol (2011) 1.62
The Human RecQ helicases, BLM and RECQ1, display distinct DNA substrate specificities. J Biol Chem (2008) 1.52
Characterising the complexity of medication safety using a human factors approach: an observational study in two intensive care units. BMJ Qual Saf (2013) 1.52
Expression profiles of osteosarcoma that can predict response to chemotherapy. Cancer Res (2005) 1.49
Multidetector computed tomography in transcatheter aortic valve implantation. JACC Cardiovasc Imaging (2011) 1.47
FANCE: the link between Fanconi anaemia complex assembly and activity. EMBO J (2002) 1.47
BRCA1-independent ubiquitination of FANCD2. Mol Cell (2003) 1.46
The mechanism of increasing outflow facility during washout in the bovine eye. Invest Ophthalmol Vis Sci (2002) 1.44
Residency training in preventive medicine: challenges and opportunities. Am J Prev Med (2005) 1.44
Apoptosis and autophagy: BIM as a mediator of tumour cell death in response to oncogene-targeted therapeutics. FEBS J (2009) 1.41
Apolipoprotein B-containing lipoproteins in retinal aging and age-related macular degeneration. J Lipid Res (2009) 1.41
UBE2T, the Fanconi anemia core complex, and FANCD2 are recruited independently to chromatin: a basis for the regulation of FANCD2 monoubiquitination. Mol Cell Biol (2007) 1.40
Can the Kattan nomogram still accurately predict prognosis in renal cell carcinoma using the revised 2010 tumor-nodes-metastasis reclassification? Int J Urol (2012) 1.38
On-film formation of bi nanowires with extraordinary electron mobility. Nano Lett (2009) 1.38
Quick-freeze/deep-etch visualization of age-related lipid accumulation in Bruch's membrane. Invest Ophthalmol Vis Sci (2003) 1.36
Expression of Bcl-2 family proteins in advanced laryngeal squamous cell carcinoma: correlation with response to chemotherapy and organ preservation. Laryngoscope (2002) 1.35
Individual right whales call louder in increased environmental noise. Biol Lett (2010) 1.31
RAD18-independent ubiquitination of proliferating-cell nuclear antigen in the avian cell line DT40. EMBO Rep (2006) 1.30
Quality of interaction between at-risk infants and caregiver at 12-15 months is associated with 3-year autism outcome. J Child Psychol Psychiatry (2012) 1.27
Secreted proteins from Mycobacterium tuberculosis gain access to the cytosolic MHC class-I antigen-processing pathway. J Immunol (2006) 1.24
Physician competencies for prescribing lifestyle medicine. JAMA (2010) 1.23
Parent-infant interaction in infant siblings at risk of autism. Res Dev Disabil (2012) 1.22
Transcatheter closure of paravalvular defects using a purpose-specific occluder. JACC Cardiovasc Interv (2010) 1.20
Aortic annulus diameter determination by multidetector computed tomography: reproducibility, applicability, and implications for transcatheter aortic valve implantation. JACC Cardiovasc Interv (2011) 1.20
Xpf and not the Fanconi anaemia proteins or Rev3 accounts for the extreme resistance to cisplatin in Dictyostelium discoideum. PLoS Genet (2009) 1.19
Conditional deletion of Pkd1 in osteocytes disrupts skeletal mechanosensing in mice. FASEB J (2011) 1.16
The effect of intrauterine myelomeningocele repair on the incidence of shunt-dependent hydrocephalus. Pediatr Neurosurg (2003) 1.15
Two studies examining environmental predictors of heavy drinking by college students. Prev Sci (2003) 1.15
A Bayesian framework for word segmentation: exploring the effects of context. Cognition (2009) 1.15
Age-related changes in human macular Bruch's membrane as seen by quick-freeze/deep-etch. Exp Eye Res (2007) 1.14
Magnetic-field-controlled reconfigurable semiconductor logic. Nature (2013) 1.14
Using molecular equivalence numbers to visually explore structural features that distinguish chemical libraries. J Chem Inf Comput Sci (2002) 1.13
Congenital high airway obstruction syndrome: MR/US findings, effect on management, and outcome. Pediatr Radiol (2008) 1.12
Stereotactic radiosurgery boost to the resection bed for oligometastatic brain disease: challenging the tradition of adjuvant whole-brain radiotherapy. Neurosurg Focus (2009) 1.11
The structure of the Lingo-1 ectodomain, a module implicated in central nervous system repair inhibition. J Biol Chem (2006) 1.11
Keeping momentum with a mouthful of water: behavior and kinematics of humpback whale lunge feeding. J Exp Biol (2012) 1.10
Adolescent daily cigarette smoking: is rural residency a risk factor? Rural Remote Health (2008) 1.10
Prostaglandin E2: from clinical applications to its potential role in bone- muscle crosstalk and myogenic differentiation. Recent Pat Biotechnol (2012) 1.10
Protected areas in Europe: principle and practice. Ann N Y Acad Sci (2008) 1.09
Model for the exceptional reactivity of peroxiredoxins 2 and 3 with hydrogen peroxide: a kinetic and computational study. J Biol Chem (2011) 1.07
The benefit of laser therapy for severe twin-twin transfusion: which metaanalysis do you pick? Am J Obstet Gynecol (2013) 1.07
Behaviour and kinematics of continuous ram filtration in bowhead whales (Balaena mysticetus). Proc Biol Sci (2009) 1.07
Genomic tagging of endogenous type IIbeta phosphatidylinositol 5-phosphate 4-kinase in DT40 cells reveals a nuclear localisation. Cell Signal (2007) 1.07
Group influences on individuals' drinking and other drug use at clubs. J Stud Alcohol Drugs (2013) 1.07
Adoptive T-cell therapy improves treatment of canine non-Hodgkin lymphoma post chemotherapy. Sci Rep (2012) 1.07
Multislice computed tomography for prediction of optimal angiographic deployment projections during transcatheter aortic valve implantation. JACC Cardiovasc Interv (2010) 1.06
A principled method for determining the functionality of brain responses. Neuroreport (2003) 1.06
Noncirrhotic portal hypertension in patients with human immunodeficiency virus-1 infection. Clin Gastroenterol Hepatol (2008) 1.06
Anthropogenic noise causes body malformations and delays development in marine larvae. Sci Rep (2013) 1.05
BIM(EL), an intrinsically disordered protein, is degraded by 20S proteasomes in the absence of poly-ubiquitylation. J Cell Sci (2011) 1.04
A small molecule inhibitor of the BLM helicase modulates chromosome stability in human cells. Chem Biol (2013) 1.04
Intervention for infants at risk of developing autism: a case series. J Autism Dev Disord (2013) 1.02
Factors associated with pathogen seroprevalence and infection in Rocky Mountain cougars. J Wildl Dis (2006) 1.02
The Fanconi anemia gene product FANCF is a flexible adaptor protein. J Biol Chem (2004) 1.00
A new view of the human trabecular meshwork using quick-freeze, deep-etch electron microscopy. Exp Eye Res (2002) 1.00
Acute compartment syndrome after minor trauma in a patient with undiagnosed mild haemophilia B. Lancet (2013) 0.99
Patient dose and image quality from mega-voltage cone beam computed tomography imaging. Med Phys (2007) 0.98
Fanconi anemia and breast cancer susceptibility. Nat Genet (2007) 0.98
Cross cultural evaluation of the Warwick-Edinburgh Mental Well-being Scale (WEMWBS) --a mixed methods study. Health Qual Life Outcomes (2013) 0.98
Calling under pressure: short-finned pilot whales make social calls during deep foraging dives. Proc Biol Sci (2011) 0.97
Morphometric analysis of lipoprotein-like particle accumulation in aging human macular Bruch's membrane. Invest Ophthalmol Vis Sci (2008) 0.97
Acoustic gaze adjustments during active target selection in echolocating porpoises. J Exp Biol (2012) 0.97
Single session stereotactic radiosurgery boost to the post-operative site in lieu of whole brain radiation in metastatic brain disease. J Neurooncol (2008) 0.96