Published in Development on August 25, 2004
On the growth and form of the gut. Nature (2011) 2.82
Nkx2-5(+)islet1(+) mesenchymal precursors generate distinct spleen stromal cell subsets and participate in restoring stromal network integrity. Immunity (2013) 1.62
Pancreatic mesenchyme regulates epithelial organogenesis throughout development. PLoS Biol (2011) 1.27
BMP and BMP receptor expression during murine organogenesis. Gene Expr Patterns (2009) 1.13
Role of the homeodomain transcription factor Bapx1 in mouse distal stomach development. Gastroenterology (2009) 1.10
Rapid differential transport of Nodal and Lefty on sulfated proteoglycan-rich extracellular matrix regulates left-right asymmetry in Xenopus. Development (2011) 1.09
Integration of left-right Pitx2 transcription and Wnt signaling drives asymmetric gut morphogenesis via Daam2. Dev Cell (2013) 0.96
Impaired spleen formation perturbs morphogenesis of the gastric lobe of the pancreas. PLoS One (2011) 0.96
Spleen versus pancreas: strict control of organ interrelationship revealed by analyses of Bapx1-/- mice. Genes Dev (2006) 0.94
Congenital asplenia in mice and humans with mutations in a Pbx/Nkx2-5/p15 module. Dev Cell (2012) 0.94
Mesenchymal bone morphogenetic protein signaling is required for normal pancreas development. Diabetes (2010) 0.90
In vivo genome-wide analysis of multiple tissues identifies gene regulatory networks, novel functions and downstream regulatory genes for Bapx1 and its co-regulation with Sox9 in the mammalian vertebral column. BMC Genomics (2014) 0.87
EphrinB1/EphB3b Coordinate Bidirectional Epithelial-Mesenchymal Interactions Controlling Liver Morphogenesis and Laterality. Dev Cell (2016) 0.83
The left-right Pitx2 pathway drives organ-specific arterial and lymphatic development in the intestine. Dev Cell (2014) 0.78
Laminin β1a controls distinct steps during the establishment of digestive organ laterality. Development (2013) 0.78
Suppression of Nkx3.2 by phosphatidylinositol-3-kinase signaling regulates cartilage development by modulating chondrocyte hypertrophy. Cell Signal (2015) 0.77
Pancreatic Mesenchyme Regulates Islet Cellular Composition in a Patched/Hedgehog-Dependent Manner. Sci Rep (2016) 0.75
Detecting microvascular changes in the mouse spleen using optical computed tomography. Microvasc Res (2015) 0.75
Noninvasive in vivo imaging of embryonic β-cell development in the anterior chamber of the eye. Islets (2016) 0.75
Isolating and Analyzing Cells of the Pancreas Mesenchyme by Flow Cytometry. J Vis Exp (2017) 0.75
Optical projection tomography as a tool for 3D microscopy and gene expression studies. Science (2002) 10.46
A long-range Shh enhancer regulates expression in the developing limb and fin and is associated with preaxial polydactyly. Hum Mol Genet (2003) 6.82
Disruption of a long-range cis-acting regulator for Shh causes preaxial polydactyly. Proc Natl Acad Sci U S A (2002) 5.18
The ectopic expression of Pax4 in the mouse pancreas converts progenitor cells into alpha and subsequently beta cells. Cell (2009) 4.47
Opposing actions of Arx and Pax4 in endocrine pancreas development. Genes Dev (2003) 4.00
An illustrated review of early pancreas development in the mouse. Endocr Rev (2007) 2.68
The ESHRE/ESGE consensus on the classification of female genital tract congenital anomalies. Hum Reprod (2013) 2.63
Enzymatic removal of ribonucleotides from DNA is essential for mammalian genome integrity and development. Cell (2012) 2.62
Exome capture reveals ZNF423 and CEP164 mutations, linking renal ciliopathies to DNA damage response signaling. Cell (2012) 2.54
Wt1 is required for cardiovascular progenitor cell formation through transcriptional control of Snail and E-cadherin. Nat Genet (2009) 2.52
Embryonic endocrine pancreas and mature beta cells acquire alpha and PP cell phenotypes upon Arx misexpression. J Clin Invest (2007) 2.46
Activated Notch1 prevents differentiation of pancreatic acinar cells and attenuate endocrine development. Dev Biol (2003) 2.41
Tomographic molecular imaging and 3D quantification within adult mouse organs. Nat Methods (2006) 2.23
Sustained Neurog3 expression in hormone-expressing islet cells is required for endocrine maturation and function. Proc Natl Acad Sci U S A (2009) 2.09
The simultaneous loss of Arx and Pax4 genes promotes a somatostatin-producing cell fate specification at the expense of the alpha- and beta-cell lineages in the mouse endocrine pancreas. Development (2005) 1.98
High-resolution three-dimensional imaging of islet-infiltrate interactions based on optical projection tomography assessments of the intact adult mouse pancreas. J Biomed Opt (2008) 1.88
Specifying pancreatic endocrine cell fates. Mech Dev (2006) 1.84
Recapitulation of embryonic neuroendocrine differentiation in adult human pancreatic duct cells expressing neurogenin 3. J Cell Biol (2002) 1.79
Point mutations in a distant sonic hedgehog cis-regulator generate a variable regulatory output responsible for preaxial polydactyly. Hum Mol Genet (2007) 1.76
Enhancer-adoption as a mechanism of human developmental disease. Hum Mutat (2011) 1.70
Expression analyses and interaction with the anaphase promoting complex protein Apc2 suggest a role for inversin in primary cilia and involvement in the cell cycle. Hum Mol Genet (2002) 1.62
Expression patterns of Wnts, Frizzleds, sFRPs, and misexpression in transgenic mice suggesting a role for Wnts in pancreas and foregut pattern formation. Dev Dyn (2002) 1.61
Clonal analysis of patterns of growth, stem cell activity, and cell movement during the development and maintenance of the murine corneal epithelium. Dev Dyn (2002) 1.59
Myt1 and Ngn3 form a feed-forward expression loop to promote endocrine islet cell differentiation. Dev Biol (2008) 1.55
Genetic determinants of pancreatic epsilon-cell development. Dev Biol (2005) 1.54
Quantification and three-dimensional imaging of the insulitis-induced destruction of beta-cells in murine type 1 diabetes. Diabetes (2010) 1.50
Long-range gene control and genetic disease. Adv Genet (2008) 1.48
Permanent Neonatal Diabetes and Enteric Anendocrinosis Associated With Biallelic Mutations in NEUROG3. Diabetes (2011) 1.47
Corneal development, limbal stem cell function, and corneal epithelial cell migration in the Pax6(+/-) mouse. Invest Ophthalmol Vis Sci (2004) 1.45
A variant in the sonic hedgehog regulatory sequence (ZRS) is associated with triphalangeal thumb and deregulates expression in the developing limb. Hum Mol Genet (2008) 1.37
An improved method for three-dimensional reconstruction of protein expression patterns in intact mouse and chicken embryos and organs. J Histochem Cytochem (2007) 1.28
Nephronophthisis. Eur J Hum Genet (2008) 1.27
The ESHRE-ESGE consensus on the classification of female genital tract congenital anomalies. Gynecol Surg (2013) 1.22
Artifactual insulin release from differentiated embryonic stem cells. Diabetes (2004) 1.22
The roles of Pax6 in the cornea, retina, and olfactory epithelium of the developing mouse embryo. Dev Biol (2003) 1.20
The effect of neurogenin3 deficiency on pancreatic gene expression in embryonic mice. J Mol Endocrinol (2006) 1.20
Opposing functions of the ETS factor family define Shh spatial expression in limb buds and underlie polydactyly. Dev Cell (2012) 1.16
A late requirement for Wnt and FGF signaling during activin-induced formation of foregut endoderm from mouse embryonic stem cells. Dev Biol (2009) 1.16
Signal sequence conservation and mature peptide divergence within subgroups of the murine beta-defensin gene family. Mol Biol Evol (2003) 1.16
Nuclear factor-{kappa}B activity in {beta}-cells is required for glucose-stimulated insulin secretion. Diabetes (2005) 1.16
Endodermal expression of Nkx6 genes depends differentially on Pdx1. Dev Biol (2005) 1.14
The role of Brn4/Pou3f4 and Pax6 in forming the pancreatic glucagon cell identity. Dev Biol (2004) 1.14
An improved protocol for optical projection tomography imaging reveals lobular heterogeneities in pancreatic islet and β-cell mass distribution. Islets (2011) 1.13
Cloning and analysis of Nkx6.3 during CNS and gastrointestinal development. Gene Expr Patterns (2005) 1.12
Human limb abnormalities caused by disruption of hedgehog signaling. Trends Genet (2012) 1.10
Mutant neurogenin-3 in congenital malabsorptive diarrhea. N Engl J Med (2007) 1.10
Preservation of proliferating pancreatic progenitor cells by Delta-Notch signaling in the embryonic chicken pancreas. BMC Dev Biol (2007) 1.08
Growth-limiting role of endothelial cells in endoderm development. Dev Biol (2011) 1.08
Generation and characterization of Ptf1a antiserum and localization of Ptf1a in relation to Nkx6.1 and Pdx1 during the earliest stages of mouse pancreas development. J Histochem Cytochem (2008) 1.08
Expression and misexpression of members of the FGF and TGFbeta families of growth factors in the developing mouse pancreas. Dev Dyn (2003) 1.07
Retinoic acid signaling organizes endodermal organ specification along the entire antero-posterior axis. PLoS One (2009) 1.05
Analysis of pancreatic endocrine development in GDF11-deficient mice. Dev Dyn (2006) 1.05
Expression of Wnt, Frizzled, sFRP, and DKK genes in adult human pancreas. Gene Expr (2003) 1.05
Pax1 and Pax9 activate Bapx1 to induce chondrogenic differentiation in the sclerotome. Development (2003) 1.04
Sonic hedgehog: restricted expression and limb dysmorphologies. J Anat (2003) 1.04
Stem cells and corneal epithelial maintenance: insights from the mouse and other animal models. Results Probl Cell Differ (2012) 1.03
Failure of transplanted bone marrow cells to adopt a pancreatic beta-cell fate. Diabetes (2006) 1.02
Mind bomb 1 is required for pancreatic β-cell formation. Proc Natl Acad Sci U S A (2012) 1.02
Nestin is expressed in vascular endothelial cells in the adult human pancreas. J Histochem Cytochem (2003) 1.01
Bapx1 regulates patterning in the middle ear: altered regulatory role in the transition from the proximal jaw during vertebrate evolution. Development (2004) 1.01
Image processing assisted algorithms for optical projection tomography. IEEE Trans Med Imaging (2011) 1.01
Retinoic acid synthesis promotes development of neural progenitors from mouse embryonic stem cells by suppressing endogenous, Wnt-dependent nodal signaling. Stem Cells (2010) 1.00
Analysis of mouse eye development with chimeras and mosaics. Int J Dev Biol (2004) 1.00
Generation and characterization of monoclonal antibodies against the transcription factor Nkx6.1. J Histochem Cytochem (2006) 1.00
Anterior-posterior differences in HoxD chromatin topology in limb development. Development (2012) 1.00
Nephronophthisis: a genetically diverse ciliopathy. Int J Nephrol (2011) 0.97
Preaxial polydactyly: a model for defective long-range regulation in congenital abnormalities. Curr Opin Genet Dev (2005) 0.96
Impaired spleen formation perturbs morphogenesis of the gastric lobe of the pancreas. PLoS One (2011) 0.96
Enhancers: from developmental genetics to the genetics of common human disease. Dev Cell (2011) 0.96
Glucose induced MAPK signalling influences NeuroD1-mediated activation and nuclear localization. FEBS Lett (2002) 0.95
Spleen versus pancreas: strict control of organ interrelationship revealed by analyses of Bapx1-/- mice. Genes Dev (2006) 0.94
Near infrared optical projection tomography for assessments of β-cell mass distribution in diabetes research. J Vis Exp (2013) 0.94
A highly conserved Wnt-dependent TCF4 binding site within the proximal enhancer of the anti-myogenic Msx1 gene supports expression within Pax3-expressing limb bud muscle precursor cells. Dev Biol (2007) 0.94
Do physicians follow systemic treatment and funding policy guidelines? Can J Clin Pharmacol (2004) 0.93
Ptf1a-mediated control of Dll1 reveals an alternative to the lateral inhibition mechanism. Development (2011) 0.93
Left-right asymmetry in gut development: what happens next? Bioessays (2009) 0.92
Inversin/Nephrocystin-2 is required for fibroblast polarity and directional cell migration. PLoS One (2013) 0.92
Towards cell therapy for diabetes. Nat Biotechnol (2006) 0.92
Generation of monoclonal antibodies against mouse neurogenin 3: a new immunocytochemical tool to study the pancreatic endocrine progenitor cell. Hybrid Hybridomics (2004) 0.92
Urinary concentration defects and mechanisms underlying nephronophthisis. Kidney Blood Press Res (2008) 0.92
Pax6 regulates regional development and neuronal migration in the cerebral cortex. Dev Biol (2003) 0.92
Radiotherapy-induced nausea and vomiting. Expert Rev Pharmacoecon Outcomes Res (2011) 0.91
Effects of aberrant Pax6 gene dosage on mouse corneal pathophysiology and corneal epithelial homeostasis. PLoS One (2011) 0.90
Mesenchymal bone morphogenetic protein signaling is required for normal pancreas development. Diabetes (2010) 0.90
Host genetics and environmental factors regulate ecological succession of the mouse colon tissue-associated microbiota. PLoS One (2012) 0.90
Bulking up on beta cells. N Engl J Med (2013) 0.90
Arx and Nkx2.2 compound deficiency redirects pancreatic alpha- and beta-cell differentiation to a somatostatin/ghrelin co-expressing cell lineage. BMC Dev Biol (2011) 0.89
EVEN-SKIPPED HOMEOBOX 1 controls human ES cell differentiation by directly repressing GOOSECOID expression. Dev Biol (2011) 0.88
Development of five digits is controlled by a bipartite long-range cis-regulator. Development (2014) 0.87
Cost-effectiveness of filgrastim and pegfilgrastim as primary prophylaxis against febrile neutropenia in lymphoma patients. J Natl Cancer Inst (2013) 0.87