Published in Cancer Epidemiol Biomarkers Prev on September 01, 2004
Genetic, Dietary and Environmental Influences on Vitamin D Metabolism | NCT02590614
Vitamin D and human health: lessons from vitamin D receptor null mice. Endocr Rev (2008) 5.28
The role of vitamin D in cancer prevention. Am J Public Health (2005) 4.99
Unexpected actions of vitamin D: new perspectives on the regulation of innate and adaptive immunity. Nat Clin Pract Endocrinol Metab (2008) 4.61
Genome-wide association study of circulating vitamin D levels. Hum Mol Genet (2010) 4.07
Higher predicted vitamin D status is associated with reduced risk of Crohn's disease. Gastroenterology (2011) 3.84
Primary prevention of colorectal cancer. Gastroenterology (2010) 3.20
Association between reduced plasma 25-hydroxy vitamin D and increased risk of cancer in patients with inflammatory bowel diseases. Clin Gastroenterol Hepatol (2013) 3.03
Solar ultraviolet-B exposure and cancer incidence and mortality in the United States, 1993-2002. BMC Cancer (2006) 2.38
Vitamin D in health and disease. Clin J Am Soc Nephrol (2008) 2.24
Frequency of leisure-time physical activity and serum 25-hydroxyvitamin D levels in the US population: results from the Third National Health and Nutrition Examination Survey. Am J Epidemiol (2008) 2.08
Calcium plus vitamin D supplementation and mortality in postmenopausal women: the Women's Health Initiative calcium-vitamin D randomized controlled trial. J Gerontol A Biol Sci Med Sci (2009) 2.01
Dose response to vitamin D supplementation in African Americans: results of a 4-arm, randomized, placebo-controlled trial. Am J Clin Nutr (2013) 1.84
Vitamin D - effects on skeletal and extraskeletal health and the need for supplementation. Nutrients (2013) 1.81
Serum levels of vitamin D metabolites and breast cancer risk in the prostate, lung, colorectal, and ovarian cancer screening trial. Cancer Epidemiol Biomarkers Prev (2008) 1.80
The influence of health and lifestyle characteristics on the relation of serum 25-hydroxyvitamin D with risk of colorectal and breast cancer in postmenopausal women. Am J Epidemiol (2012) 1.62
Circulating levels of vitamin D and colon and rectal cancer: the Physicians' Health Study and a meta-analysis of prospective studies. Cancer Prev Res (Phila) (2011) 1.62
Prospective study of serum 25(OH)-vitamin D concentration and risk of oesophageal and gastric cancers. Br J Cancer (2007) 1.60
Time course of risk factors in cancer etiology and progression. J Clin Oncol (2010) 1.46
Association between plasma 25-hydroxyvitamin D and breast cancer risk. Cancer Prev Res (Phila) (2009) 1.44
Sunlight and Vitamin D: A global perspective for health. Dermatoendocrinol (2013) 1.41
Prospective study of predictors of vitamin D status and survival in patients with colorectal cancer. Br J Cancer (2009) 1.41
Comprehensive association analysis of nine candidate genes with serum 25-hydroxy vitamin D levels among healthy Caucasian subjects. Hum Genet (2010) 1.31
Plasma 25-hydroxyvitamin D levels and the risk of colorectal cancer: the multiethnic cohort study. Cancer Epidemiol Biomarkers Prev (2010) 1.30
Effect of interval between serum draw and follow-up period on relative risk of cancer incidence with respect to 25-hydroxyvitamin D level: Implications for meta-analyses and setting vitamin D guidelines. Dermatoendocrinol (2011) 1.29
Association of sedentary behaviour with colon and rectal cancer: a meta-analysis of observational studies. Br J Cancer (2013) 1.29
Plasma vitamin D and risk of colorectal cancer: the Japan Public Health Center-Based Prospective Study. Br J Cancer (2007) 1.22
Prediagnostic 25-hydroxyvitamin D, VDR and CASR polymorphisms, and survival in patients with colorectal cancer in western European ppulations. Cancer Epidemiol Biomarkers Prev (2012) 1.20
Low vitamin D status: definition, prevalence, consequences, and correction. Endocrinol Metab Clin North Am (2010) 1.18
Vitamin D and cancer. Front Endocrinol (Lausanne) (2012) 1.15
Vitamin D related genes, CYP24A1 and CYP27B1, and colon cancer risk. Cancer Epidemiol Biomarkers Prev (2009) 1.13
Cholecalciferol (vitamin D3) inhibits growth and invasion by up-regulating nuclear receptors and 25-hydroxylase (CYP27A1) in human prostate cancer cells. Clin Exp Metastasis (2005) 1.12
Determinants of serum 25 hydroxyvitamin D levels in a nationwide cohort of blacks and non-Hispanic whites. Cancer Causes Control (2009) 1.10
Genetic variation in the vitamin D receptor (VDR) and the vitamin D-binding protein (GC) and risk for colorectal cancer: results from the Colon Cancer Family Registry. Cancer Epidemiol Biomarkers Prev (2010) 1.07
Chemotherapy is linked to severe vitamin D deficiency in patients with colorectal cancer. Int J Colorectal Dis (2008) 1.07
The yin and yang of vitamin D receptor (VDR) signaling in neoplastic progression: operational networks and tissue-specific growth control. Biochem Pharmacol (2009) 1.06
Association of vitamin D receptor gene variants, adiposity and colon cancer. Carcinogenesis (2008) 1.05
Blood 25-hydroxyvitamin D3 concentrations and incident sporadic colorectal adenoma risk: a pooled case-control study. Am J Epidemiol (2010) 1.04
Genetic polymorphisms in vitamin D receptor VDR/RXRA influence the likelihood of colon adenoma recurrence. Cancer Res (2010) 1.04
Serum 25-hydroxyvitamin D is inversely associated with body mass index in cancer. Nutr J (2011) 1.01
MicroRNA-627 mediates the epigenetic mechanisms of vitamin D to suppress proliferation of human colorectal cancer cells and growth of xenograft tumors in mice. Gastroenterology (2013) 0.99
Assessment and interpretation of circulating 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D in the clinical environment. Endocrinol Metab Clin North Am (2010) 0.98
Common variants of the vitamin D binding protein gene and adverse health outcomes. Crit Rev Clin Lab Sci (2013) 0.98
User-centered development of a smart phone mobile application delivering personalized real-time advice on sun protection. Transl Behav Med (2013) 0.97
Serum 25-hydroxyvitamin D and risks of colon and rectal cancer in Finnish men. Am J Epidemiol (2011) 0.97
Prevention of preneoplastic lesions by dietary vitamin D in a mouse model of colorectal carcinogenesis. J Steroid Biochem Mol Biol (2012) 0.96
Sunlight, hormone replacement status and colorectal cancer risk in postmenopausal women. Int J Cancer (2010) 0.93
Plasma homocysteine and cysteine and risk of breast cancer in women. Cancer Res (2010) 0.93
Vitamin D and Colorectal, Breast, and Prostate Cancers: A Review of the Epidemiological Evidence. J Cancer (2016) 0.92
Serum 25-hydroxyvitamin D, vitamin D binding protein and risk of colorectal cancer in the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial. Int J Cancer (2014) 0.92
How much vitamin D do we need for skeletal health? Clin Orthop Relat Res (2011) 0.91
Vitamin D and gastrointestinal diseases: inflammatory bowel disease and colorectal cancer. Therap Adv Gastroenterol (2011) 0.90
Supplementation by vitamin D compounds does not affect colonic tumor development in vitamin D sufficient murine models. Arch Biochem Biophys (2011) 0.90
New perspectives on vitamin D food fortification based on a modeling of 25(OH)D concentrations. Nutr J (2013) 0.89
Impact of oral vitamin D supplementation on serum 25-hydroxyvitamin D levels in oncology. Nutr J (2010) 0.89
Circulating Vitamin D Levels and Risk of Colorectal Cancer in Women. Cancer Prev Res (Phila) (2015) 0.88
Genetic variation in vitamin D-related genes and risk of colorectal cancer in African Americans. Cancer Causes Control (2014) 0.87
CYP24A1 inhibition facilitates the anti-tumor effect of vitamin D3 on colorectal cancer cells. World J Gastroenterol (2013) 0.87
Circulating vitamin d and risk of epithelial ovarian cancer. J Oncol (2009) 0.87
Reproductive factors and risk of primary brain tumors in women. J Neurooncol (2014) 0.86
New insights into calcium, dairy and colon cancer. World J Gastroenterol (2008) 0.86
Interactions between plasma levels of 25-hydroxyvitamin D, insulin-like growth factor (IGF)-1 and C-peptide with risk of colorectal cancer. PLoS One (2011) 0.86
Prevalence of serum vitamin D deficiency and insufficiency in cancer: Review of the epidemiological literature. Exp Ther Med (2011) 0.85
Genetic predictors of circulating 25-hydroxyvitamin d and risk of colorectal cancer. Cancer Epidemiol Biomarkers Prev (2013) 0.84
Associations between circulating 1,25(OH)₂D concentration and odds of metachronous colorectal adenoma. Cancer Causes Control (2014) 0.83
Relationship between vitamin D deficiency and cardiovascular disease. World J Cardiol (2013) 0.83
Genetic associations in the vitamin D receptor and colorectal cancer in African Americans and Caucasians. PLoS One (2011) 0.83
Using components of the vitamin D pathway to prevent and treat colon cancer. Nutr Rev (2012) 0.83
Low serum 25-hydroxyvitamin d concentrations are associated with increased risk for melanoma and unfavourable prognosis. PLoS One (2014) 0.83
Protective links between vitamin D, inflammatory bowel disease and colon cancer. World J Gastroenterol (2016) 0.82
Pre-diagnostic plasma 25-hydroxyvitamin D levels and risk of non-melanoma skin cancer in women. PLoS One (2012) 0.82
Association between circulating concentrations of 25(OH)D and colorectal adenoma: a pooled analysis. Int J Cancer (2013) 0.82
The Breast Cancer to Bone (B2B) Metastases Research Program: a multi-disciplinary investigation of bone metastases from breast cancer. BMC Cancer (2015) 0.81
New perspectives on vitamin D sources in Germany based on a novel mathematical bottom-up model of 25(OH)D serum concentrations. Eur J Nutr (2012) 0.81
Prevention of colorectal cancer and dietary management. Chin Clin Oncol (2013) 0.80
Vitamin D receptor and retinoid X receptor α status and vitamin D insufficiency in models of murine colitis. Cancer Prev Res (Phila) (2013) 0.80
Plasma 25-Hydroxyvitamin D, Vitamin D Binding Protein, and Risk of Colorectal Cancer in the Nurses' Health Study. Cancer Prev Res (Phila) (2016) 0.80
Effect of Vitamin D3 Supplementation in Combination with Weight Loss on Inflammatory Biomarkers in Postmenopausal Women: A Randomized Controlled Trial. Cancer Prev Res (Phila) (2015) 0.80
Mortality and causes of deaths of inhabitants with renal dysfunction induced by cadmium exposure of the polluted Jinzu River basin, Toyama, Japan; a 26-year follow-up. Environ Health (2014) 0.79
The vitamin D receptor (VDR) gene polymorphisms in Turkish brain cancer patients. Biomed Res Int (2013) 0.78
Circulating vitamin D binding protein, total, free and bioavailable 25-hydroxyvitamin D and risk of colorectal cancer. Sci Rep (2015) 0.78
Proportion of colon cancer attributable to lifestyle in a cohort of US women. Cancer Causes Control (2015) 0.78
Joint effects of colorectal cancer susceptibility loci, circulating 25-hydroxyvitamin D and risk of colorectal cancer. PLoS One (2014) 0.78
Relationship between 25-hydroxyvitamin D and metabolic syndrome among Jordanian adults. Nutr Res Pract (2011) 0.78
25-Hydroxyvitamin D Status and Risk for Colorectal Cancer and Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis of Epidemiological Studies. Int J Environ Res Public Health (2017) 0.77
Serum vitamin D levels among patients in a clinical oncology practice compared to primary care patients in the same community: a case-control study. BMJ Open (2011) 0.77
Disparities in Uveal Melanoma: Patient Characteristics. Semin Ophthalmol (2016) 0.77
Colorectal Cancer Epidemiology in the Nurses' Health Study. Am J Public Health (2016) 0.77
Physical activity, sedentary behavior, and vitamin D metabolites. Bone (2015) 0.76
The effect of 1,25 dihydroxyvitamin D3 treatment on the mRNA levels of β catenin target genes in mice with colonic inactivation of both APC alleles. J Steroid Biochem Mol Biol (2015) 0.76
Vitamin D for Prevention and Treatment of Colorectal Cancer: What is the Evidence? Curr Colorectal Cancer Rep (2014) 0.76
Chemoprevention for colorectal neoplasia. Clin Colon Rectal Surg (2008) 0.75
A new sensitive LC/MS/MS analysis of vitamin D metabolites using a click derivatization reagent, 2-nitrosopyridine. J Lipid Res (2017) 0.75
Vitamin D and Physical Activity in Patients With Colorectal Cancer: Epidemiological Evidence and Therapeutic Implications. Cancer J (2016) 0.75
CYP24A1 and CYP27B1 Polymorphisms, Concentrations of Vitamin D Metabolites, and Odds of Colorectal Adenoma Recurrence. Nutr Cancer (2015) 0.75
Genome-wide association study identifies novel breast cancer susceptibility loci. Nature (2007) 29.23
A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer. Nat Genet (2007) 22.96
Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response. Science (2006) 18.74
Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia. Nature (2007) 17.68
Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet (2008) 15.94
A randomized controlled trial of fluorouracil plus leucovorin, irinotecan, and oxaliplatin combinations in patients with previously untreated metastatic colorectal cancer. J Clin Oncol (2003) 12.24
Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia. N Engl J Med (2009) 10.54
BCR-ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros. Nature (2008) 10.12
The genetic basis of early T-cell precursor acute lymphoblastic leukaemia. Nature (2012) 9.89
Large-scale sequence analysis of avian influenza isolates. Science (2006) 9.87
Genomic analysis of the clonal origins of relapsed acute lymphoblastic leukemia. Science (2008) 9.25
Aspirin and the risk of colorectal cancer in relation to the expression of COX-2. N Engl J Med (2007) 9.04
A multistage genome-wide association study in breast cancer identifies two new risk alleles at 1p11.2 and 14q24.1 (RAD51L1). Nat Genet (2009) 8.39
The Nurses' Health Study: lifestyle and health among women. Nat Rev Cancer (2005) 8.19
25-hydroxyvitamin D and risk of myocardial infarction in men: a prospective study. Arch Intern Med (2008) 8.03
Long-term colorectal-cancer incidence and mortality after lower endoscopy. N Engl J Med (2013) 7.72
Aspirin use, tumor PIK3CA mutation, and colorectal-cancer survival. N Engl J Med (2012) 7.47
Hypovitaminosis D prevalence and determinants among African American and white women of reproductive age: third National Health and Nutrition Examination Survey, 1988-1994. Am J Clin Nutr (2002) 7.34
Blood levels of long-chain n-3 fatty acids and the risk of sudden death. N Engl J Med (2002) 7.32
Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2. Nat Genet (2009) 7.30
Prospective study of predictors of vitamin D status and cancer incidence and mortality in men. J Natl Cancer Inst (2006) 7.19
Serum 25-hydroxyvitamin D levels and risk of multiple sclerosis. JAMA (2006) 7.09
Diet quality and major chronic disease risk in men and women: moving toward improved dietary guidance. Am J Clin Nutr (2002) 6.96
Aspirin use and survival after diagnosis of colorectal cancer. JAMA (2009) 6.93
Evolution of human BCR-ABL1 lymphoblastic leukaemia-initiating cells. Nature (2011) 6.39
Insulin-like growth factors and neoplasia. Nat Rev Cancer (2004) 6.29
CpG island methylator phenotype, microsatellite instability, BRAF mutation and clinical outcome in colon cancer. Gut (2008) 6.26
CDK8 is a colorectal cancer oncogene that regulates beta-catenin activity. Nature (2008) 6.24
Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics. PLoS Genet (2008) 6.22
Analysis of the coding genome of diffuse large B-cell lymphoma. Nat Genet (2011) 6.06
Sensitive sequencing method for KRAS mutation detection by Pyrosequencing. J Mol Diagn (2005) 6.00
Inflammatory markers and the risk of coronary heart disease in men and women. N Engl J Med (2004) 5.86
Performance of common genetic variants in breast-cancer risk models. N Engl J Med (2010) 5.79
Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia. N Engl J Med (2014) 5.37
CREST maps somatic structural variation in cancer genomes with base-pair resolution. Nat Methods (2011) 5.34
Body-mass index and symptoms of gastroesophageal reflux in women. N Engl J Med (2006) 5.24
Physical activity and survival after colorectal cancer diagnosis. J Clin Oncol (2006) 5.22
Inactivating mutations of acetyltransferase genes in B-cell lymphoma. Nature (2011) 5.20
Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer. Nat Genet (2009) 5.14
A novel retinoblastoma therapy from genomic and epigenetic analyses. Nature (2012) 5.02
Variable clonal repopulation dynamics influence chemotherapy response in colorectal cancer. Science (2012) 4.92
A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1 and 5p15.33. Nat Genet (2010) 4.89
Novel mutations target distinct subgroups of medulloblastoma. Nature (2012) 4.82
ABO blood group and the risk of pancreatic cancer. J Natl Cancer Inst (2009) 4.72
Precision and performance characteristics of bisulfite conversion and real-time PCR (MethyLight) for quantitative DNA methylation analysis. J Mol Diagn (2006) 4.68
Vasectomy and risk of aggressive prostate cancer: a 24-year follow-up study. J Clin Oncol (2014) 4.67
Serum vitamin D levels and markers of severity of childhood asthma in Costa Rica. Am J Respir Crit Care Med (2009) 4.64
A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation. PLoS Genet (2008) 4.57
Risk factors for breast cancer according to estrogen and progesterone receptor status. J Natl Cancer Inst (2004) 4.57
Associations of breast cancer risk factors with tumor subtypes: a pooled analysis from the Breast Cancer Association Consortium studies. J Natl Cancer Inst (2010) 4.54
Efficacy, safety, and potential biomarkers of sunitinib monotherapy in advanced hepatocellular carcinoma: a phase II study. J Clin Oncol (2009) 4.54
Aspirin intake and survival after breast cancer. J Clin Oncol (2010) 4.50
Genetic alterations activating kinase and cytokine receptor signaling in high-risk acute lymphoblastic leukemia. Cancer Cell (2012) 4.41
Microsatellite instability and BRAF mutation testing in colorectal cancer prognostication. J Natl Cancer Inst (2013) 4.37
Analysis of the chronic lymphocytic leukemia coding genome: role of NOTCH1 mutational activation. J Exp Med (2011) 4.37
The urgent need to recommend an intake of vitamin D that is effective. Am J Clin Nutr (2007) 4.36
Rearrangement of CRLF2 in B-progenitor- and Down syndrome-associated acute lymphoblastic leukemia. Nat Genet (2009) 4.35
Impact of physical activity on cancer recurrence and survival in patients with stage III colon cancer: findings from CALGB 89803. J Clin Oncol (2006) 4.27
Moderate alcohol consumption during adult life, drinking patterns, and breast cancer risk. JAMA (2011) 4.25
A prospective study of long-term intake of dietary fiber and risk of Crohn's disease and ulcerative colitis. Gastroenterology (2013) 4.06
Body iron stores in relation to risk of type 2 diabetes in apparently healthy women. JAMA (2004) 4.04
Comparison of risk factors for colon and rectal cancer. Int J Cancer (2004) 4.03
Molecular pathological epidemiology of colorectal neoplasia: an emerging transdisciplinary and interdisciplinary field. Gut (2010) 4.01
CpG island methylator phenotype-low (CIMP-low) in colorectal cancer: possible associations with male sex and KRAS mutations. J Mol Diagn (2006) 3.98
Association of nut consumption with total and cause-specific mortality. N Engl J Med (2013) 3.94
Long-term use of aspirin and nonsteroidal anti-inflammatory drugs and risk of colorectal cancer. JAMA (2005) 3.88
Higher predicted vitamin D status is associated with reduced risk of Crohn's disease. Gastroenterology (2011) 3.84
Genome-wide association studies identify four ER negative-specific breast cancer risk loci. Nat Genet (2013) 3.81
Gene expression profiling of pediatric acute myelogenous leukemia. Blood (2004) 3.77
Ultraviolet-B radiation increases serum 25-hydroxyvitamin D levels: the effect of UVB dose and skin color. J Am Acad Dermatol (2007) 3.74
CREBBP mutations in relapsed acute lymphoblastic leukaemia. Nature (2011) 3.72
Vitamin D2 is much less effective than vitamin D3 in humans. J Clin Endocrinol Metab (2004) 3.71
Detectable clonal mosaicism and its relationship to aging and cancer. Nat Genet (2012) 3.69
Endogenous steroid hormone concentrations and risk of breast cancer among premenopausal women. J Natl Cancer Inst (2006) 3.65
Evaluation of markers for CpG island methylator phenotype (CIMP) in colorectal cancer by a large population-based sample. J Mol Diagn (2007) 3.56
Zinc supplement use and risk of prostate cancer. J Natl Cancer Inst (2003) 3.54
Restriction of intestinal stem cell expansion and the regenerative response by YAP. Nature (2012) 3.54
A cohort study of tumoral LINE-1 hypomethylation and prognosis in colon cancer. J Natl Cancer Inst (2008) 3.54
Serum vitamin D levels and severe asthma exacerbations in the Childhood Asthma Management Program study. J Allergy Clin Immunol (2010) 3.54
Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas. Nat Genet (2013) 3.51