Published in N Engl J Med on September 02, 2004
Study of Leptin for the Treatment of Hypothalamic Amenorrhea | NCT00130117
Cellular bioenergetics as a target for obesity therapy. Nat Rev Drug Discov (2010) 4.23
The hormonal control of food intake. Cell (2007) 3.61
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. Nat Genet (2010) 3.37
Low-dose leptin reverses skeletal muscle, autonomic, and neuroendocrine adaptations to maintenance of reduced weight. J Clin Invest (2005) 3.10
Obesity and leptin resistance: distinguishing cause from effect. Trends Endocrinol Metab (2010) 2.79
The geometry of leptin action in the brain: more complicated than a simple ARC. Cell Metab (2009) 2.69
Relationships between fat and bone. Osteoporos Int (2007) 2.51
Leptin at 14 y of age: an ongoing story. Am J Clin Nutr (2009) 2.33
Modulation of appetite by gonadal steroid hormones. Philos Trans R Soc Lond B Biol Sci (2006) 2.30
Narrative review: the role of leptin in human physiology: emerging clinical applications. Ann Intern Med (2010) 2.00
Leptin in human physiology and pathophysiology. Am J Physiol Endocrinol Metab (2011) 1.99
Independent circadian and sleep/wake regulation of adipokines and glucose in humans. J Clin Endocrinol Metab (2005) 1.81
The genetic and molecular basis of idiopathic hypogonadotropic hypogonadism. Nat Rev Endocrinol (2009) 1.81
Cord blood leptin and adiponectin as predictors of adiposity in children at 3 years of age: a prospective cohort study. Pediatrics (2009) 1.70
Critical role of STAT3 in leptin's metabolic actions. Cell Metab (2006) 1.70
Adaptive thermogenesis in humans. Int J Obes (Lond) (2010) 1.69
Adipokines and the peripheral and neural control of energy balance. Mol Endocrinol (2008) 1.66
Leptin revisited: its mechanism of action and potential for treating diabetes. Nat Rev Drug Discov (2012) 1.63
Leptin and the sympathetic connection of fat to bone. Osteoporos Int (2007) 1.61
Strategies to reverse bone loss in women with functional hypothalamic amenorrhea: a systematic review of the literature. Osteoporos Int (2008) 1.51
An age-dependent interaction with leptin unmasks ghrelin's bone-protective effects. Endocrinology (2012) 1.50
Leptin's effect on puberty in mice is relayed by the ventral premammillary nucleus and does not require signaling in Kiss1 neurons. J Clin Invest (2010) 1.49
Differential regulation of metabolic, neuroendocrine, and immune function by leptin in humans. Proc Natl Acad Sci U S A (2006) 1.46
Leptin in human physiology and therapeutics. Front Neuroendocrinol (2010) 1.46
Long-term efficacy of leptin replacement in patients with Dunnigan-type familial partial lipodystrophy. Metabolism (2007) 1.40
Fat targets for skeletal health. Nat Rev Rheumatol (2009) 1.36
Leptin in humans: lessons from translational research. Am J Clin Nutr (2009) 1.35
Leptin is an effective treatment for hypothalamic amenorrhea. Proc Natl Acad Sci U S A (2011) 1.26
A genetic basis for functional hypothalamic amenorrhea. N Engl J Med (2011) 1.24
Challenges and opportunities of defining clinical leptin resistance. Cell Metab (2012) 1.21
Preadipocyte factor-1 is associated with marrow adiposity and bone mineral density in women with anorexia nervosa. J Clin Endocrinol Metab (2009) 1.18
Sex differences in the physiology of eating. Am J Physiol Regul Integr Comp Physiol (2013) 1.18
The ventral premammillary nucleus links fasting-induced changes in leptin levels and coordinated luteinizing hormone secretion. J Neurosci (2009) 1.18
Physiology of leptin: energy homeostasis, neuroendocrine function and metabolism. Metabolism (2014) 1.18
Leptin administration does not prevent the bone mineral metabolism changes induced by weight loss. Metabolism (2011) 1.17
Physiologic estrogen replacement increases bone density in adolescent girls with anorexia nervosa. J Bone Miner Res (2011) 1.16
Thyroid hormones and the metabolic syndrome. Eur Thyroid J (2013) 1.10
Efficacy of metreleptin in obese patients with type 2 diabetes: cellular and molecular pathways underlying leptin tolerance. Diabetes (2011) 1.10
Clinical relevance of adipokines. Diabetes Metab J (2012) 1.10
Leptin's role in lipodystrophic and nonlipodystrophic insulin-resistant and diabetic individuals. Endocr Rev (2013) 1.10
Hypothalamic sites of leptin action linking metabolism and reproduction. Neuroendocrinology (2010) 1.06
Pharmacokinetics of subcutaneous recombinant methionyl human leptin administration in healthy subjects in the fed and fasting states: regulation by gender and adiposity. Clin Pharmacokinet (2008) 1.05
The acute effects of leptin require PI3K signaling in the hypothalamic ventral premammillary nucleus. J Neurosci (2011) 1.03
Leptin does not mediate short-term fasting-induced changes in growth hormone pulsatility but increases IGF-I in leptin deficiency states. J Clin Endocrinol Metab (2008) 1.02
Revisiting leptin's role in obesity and weight loss. J Clin Invest (2008) 1.02
Energy deprivation alters in a leptin- and cortisol-independent manner circulating levels of activin A and follistatin but not myostatin in healthy males. J Clin Endocrinol Metab (2011) 1.01
Leptin signaling and circuits in puberty and fertility. Cell Mol Life Sci (2012) 1.01
Leptin is not the critical signal for kisspeptin or luteinising hormone restoration during exit from negative energy balance. J Neuroendocrinol (2011) 1.01
Evidence that obesity and androgens have independent and opposing effects on gonadotropin production from puberty to maturity. Brain Res (2010) 1.01
Effects of recombinant human growth hormone in anorexia nervosa: a randomized, placebo-controlled study. J Clin Endocrinol Metab (2010) 1.00
Leptin and Adiponectin in the HIV Associated Metabolic Syndrome: Physiologic and Therapeutic Implications. Am J Infect Dis (2006) 1.00
Higher ghrelin and lower leptin secretion are associated with lower LH secretion in young amenorrheic athletes compared with eumenorrheic athletes and controls. Am J Physiol Endocrinol Metab (2012) 0.97
The Changes They are A-Timed: Metabolism, Endogenous Clocks, and the Timing of Puberty. Front Endocrinol (Lausanne) (2012) 0.97
Endocrine consequences of anorexia nervosa. Lancet Diabetes Endocrinol (2014) 0.95
The ventral premammillary nucleus links metabolic cues and reproduction. Front Endocrinol (Lausanne) (2011) 0.95
The role of leptin in regulating bone metabolism. Metabolism (2014) 0.95
Bone metabolism in adolescent boys with anorexia nervosa. J Clin Endocrinol Metab (2008) 0.95
Obesity and PCOS: implications for diagnosis and treatment. Semin Reprod Med (2012) 0.94
The female athlete triad. Sports Health (2012) 0.91
Colitis causes delay in puberty in female mice out of proportion to changes in leptin and corticosterone. J Gastroenterol (2010) 0.91
Obesity and lipodystrophy--where do the circles intersect? Endocrinology (2008) 0.91
Genetics of isolated hypogonadotropic hypogonadism: role of GnRH receptor and other genes. Int J Endocrinol (2011) 0.91
Regulation of thyrotropin-releasing hormone-expressing neurons in paraventricular nucleus of the hypothalamus by signals of adiposity. Mol Endocrinol (2010) 0.91
Comparative endocrinology of leptin: assessing function in a phylogenetic context. Gen Comp Endocrinol (2014) 0.91
r-metHuLeptin improves highly active antiretroviral therapy-induced lipoatrophy and the metabolic syndrome, but not through altering circulating IGF and IGF-binding protein levels: observational and interventional studies in humans. Eur J Endocrinol (2008) 0.90
Absence of functional leptin receptor isoforms in the POUND (Lepr(db/lb)) mouse is associated with muscle atrophy and altered myoblast proliferation and differentiation. PLoS One (2013) 0.90
Chemerin is expressed mainly in pancreas and liver, is regulated by energy deprivation, and lacks day/night variation in humans. Eur J Endocrinol (2013) 0.90
Preadipocyte factor-1 levels are higher in women with hypothalamic amenorrhea and are associated with bone mineral content and bone mineral density through a mechanism independent of leptin. J Clin Endocrinol Metab (2011) 0.90
Endocrine dysregulation in anorexia nervosa update. J Clin Endocrinol Metab (2011) 0.90
Leptin as a modulator of neuroendocrine function in humans. Yonsei Med J (2012) 0.90
Clinical review: Adolescent anovulation: maturational mechanisms and implications. J Clin Endocrinol Metab (2013) 0.89
Leptin-dependent neuronal NO signaling in the preoptic hypothalamus facilitates reproduction. J Clin Invest (2014) 0.89
Cross-Talk between Metabolism and Reproduction: The Role of POMC and SF1 Neurons. Front Endocrinol (Lausanne) (2012) 0.88
Leptin-responsive GABAergic neurons regulate fertility through pathways that result in reduced kisspeptinergic tone. J Neurosci (2014) 0.88
Acylated ghrelin and leptin in adolescent athletes with amenorrhea, eumenorrheic athletes and controls: a cross-sectional study. Clin Endocrinol (Oxf) (2008) 0.88
Short-term energy deprivation alters activin a and follistatin but not inhibin B levels of lean healthy women in a leptin-independent manner. J Clin Endocrinol Metab (2011) 0.88
Insulin resistance is a sufficient basis for hyperandrogenism in lipodystrophic women with polycystic ovarian syndrome. J Clin Endocrinol Metab (2011) 0.87
Peptide YY in adolescent athletes with amenorrhea, eumenorrheic athletes and non-athletic controls. Bone (2009) 0.87
Anorexia nervosa and bone. J Endocrinol (2014) 0.87
Anorexia nervosa, osteoporosis and circulating leptin: the missing link. Osteoporos Int (2010) 0.87
A potential mechanism for the sexual dimorphism in the onset of puberty and incidence of idiopathic central precocious puberty in children: sex-specific kisspeptin as an integrator of puberty signals. Front Endocrinol (Lausanne) (2012) 0.87
Serum leptin levels and reproductive function during the menstrual cycle. Am J Obstet Gynecol (2013) 0.86
New pharmacological perspectives for the leptin receptor in the treatment of obesity. Front Endocrinol (Lausanne) (2014) 0.86
Randomized double-blind placebo-controlled study of leptin administration after gastric bypass. Obesity (Silver Spring) (2013) 0.86
Anorexia nervosa, obesity and bone metabolism. Pediatr Endocrinol Rev (2013) 0.86
The long-term clinical follow-up and natural history of men with adult-onset idiopathic hypogonadotropic hypogonadism. J Clin Endocrinol Metab (2010) 0.85
Expression of adipokines in preimplantation rabbit and mice embryos. Histochem Cell Biol (2008) 0.85
Analysis of stress fractures in athletes based on our clinical experience. World J Orthop (2011) 0.85
Hypogonadism in male cancer patients. J Cachexia Sarcopenia Muscle (2012) 0.85
Repositioning leptin as a therapy for Alzheimer's disease. Therapy (2011) 0.85
Beyond Leptin: Emerging Candidates for the Integration of Metabolic and Reproductive Function during Negative Energy Balance. Front Endocrinol (Lausanne) (2011) 0.84
The source of leptin, but not leptin depletion in response to food restriction, changes during early pregnancy in mice. Endocrine (2011) 0.84
Cocaine- and amphetamine-regulated transcript is a potent stimulator of GnRH and kisspeptin cells and may contribute to negative energy balance-induced reproductive inhibition in females. Endocrinology (2013) 0.84
Skeletal complications of eating disorders. Metabolism (2015) 0.84
Leptin treatment reduces body fat but does not affect lean body mass or the myostatin-follistatin-activin axis in lean hypoleptinemic women. Am J Physiol Endocrinol Metab (2011) 0.84
Fibroblast growth factor 21 levels in young healthy females display day and night variations and are increased in response to short-term energy deprivation through a leptin-independent pathway. Diabetes Care (2012) 0.84
Leptin administration to overweight and obese subjects for 6 months increases free leptin concentrations but does not alter circulating hormones of the thyroid and IGF axes during weight loss induced by a mild hypocaloric diet. Eur J Endocrinol (2011) 0.83
Endocrinology: the active partner in PNI research. Brain Behav Immun (2006) 0.83
Novel strategy for the use of leptin for obesity therapy. Expert Opin Biol Ther (2011) 0.83
Leptin-replacement therapy for lipodystrophy. N Engl J Med (2002) 7.78
Adverse metabolic and cardiovascular consequences of circadian misalignment. Proc Natl Acad Sci U S A (2009) 6.67
Deliberations about deliberative methods: issues in the design and evaluation of public participation processes. Soc Sci Med (2003) 6.00
Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency. J Clin Invest (2002) 5.83
Diabetes mellitus and risk of breast cancer: a meta-analysis. Int J Cancer (2007) 5.57
Leptin reverses insulin resistance and hepatic steatosis in patients with severe lipodystrophy. J Clin Invest (2002) 4.75
Identification of proteins in human cytomegalovirus (HCMV) particles: the HCMV proteome. J Virol (2004) 4.30
FNDC5 and irisin in humans: I. Predictors of circulating concentrations in serum and plasma and II. mRNA expression and circulating concentrations in response to weight loss and exercise. Metabolism (2012) 3.61
Dietary patterns and risk of mortality from cardiovascular disease, cancer, and all causes in a prospective cohort of women. Circulation (2008) 3.56
Mediterranean diet and incidence of and mortality from coronary heart disease and stroke in women. Circulation (2009) 3.47
Low plasma adiponectin levels and risk of colorectal cancer in men: a prospective study. J Natl Cancer Inst (2005) 3.22
A single-dose placebo-controlled study of AMG 162, a fully human monoclonal antibody to RANKL, in postmenopausal women. J Bone Miner Res (2004) 3.17
Leptin in immunology. J Immunol (2005) 2.62
Circulating adiponectin and resistin levels in relation to metabolic factors, inflammatory markers, and vascular reactivity in diabetic patients and subjects at risk for diabetes. Diabetes Care (2004) 2.55
The role of falling leptin levels in the neuroendocrine and metabolic adaptation to short-term starvation in healthy men. J Clin Invest (2003) 2.42
Phenotypic effects of leptin replacement on morbid obesity, diabetes mellitus, hypogonadism, and behavior in leptin-deficient adults. Proc Natl Acad Sci U S A (2004) 2.41
Adiponectin in relation to malignancies: a review of existing basic research and clinical evidence. Am J Clin Nutr (2007) 2.40
Circulating resistin levels are not associated with obesity or insulin resistance in humans and are not regulated by fasting or leptin administration: cross-sectional and interventional studies in normal, insulin-resistant, and diabetic subjects. J Clin Endocrinol Metab (2003) 2.25
Adiponectin in insulin resistance: lessons from translational research. Am J Clin Nutr (2009) 2.22
Circulating irisin in relation to insulin resistance and the metabolic syndrome. J Clin Endocrinol Metab (2013) 2.16
Serum adiponectin levels are inversely associated with overall and central fat distribution but are not directly regulated by acute fasting or leptin administration in humans: cross-sectional and interventional studies. J Clin Endocrinol Metab (2003) 2.09
Reproducibility of plasma and urine biomarkers among premenopausal and postmenopausal women from the Nurses' Health Studies. Cancer Epidemiol Biomarkers Prev (2010) 2.09
Plasma adiponectin concentrations and risk of incident breast cancer. J Clin Endocrinol Metab (2007) 2.07
Coffee consumption is associated with higher plasma adiponectin concentrations in women with or without type 2 diabetes: a prospective cohort study. Diabetes Care (2007) 2.06
Total and high-molecular weight adiponectin in relation to metabolic variables at baseline and in response to an exercise treatment program: comparative evaluation of three assays. Diabetes Care (2007) 2.04
The role of the IGF system in cancer: from basic to clinical studies and clinical applications. Oncology (2002) 2.03
Total and high-molecular-weight adiponectin and resistin in relation to the risk for type 2 diabetes in women. Ann Intern Med (2008) 2.01
Narrative review: the role of leptin in human physiology: emerging clinical applications. Ann Intern Med (2010) 2.00
Sleep duration and snoring in relation to biomarkers of cardiovascular disease risk among women with type 2 diabetes. Diabetes Care (2007) 1.99
Circulating insulin and c-peptide levels and risk of breast cancer among predominately premenopausal women. Cancer Epidemiol Biomarkers Prev (2007) 1.95
High-dosage ascorbic acid treatment in Charcot-Marie-Tooth disease type 1A: results of a randomized, double-masked, controlled trial. JAMA Neurol (2013) 1.90
Drug Insight: the role of leptin in human physiology and pathophysiology--emerging clinical applications. Nat Clin Pract Endocrinol Metab (2006) 1.88
Circulating adiponectin and endometrial cancer risk. J Clin Endocrinol Metab (2004) 1.86
Diurnal and ultradian dynamics of serum adiponectin in healthy men: comparison with leptin, circulating soluble leptin receptor, and cortisol patterns. J Clin Endocrinol Metab (2003) 1.84
Type 2 diabetes mellitus and medications for type 2 diabetes mellitus are associated with risk for and mortality from cancer in a German primary care cohort. Metabolism (2010) 1.81
Independent circadian and sleep/wake regulation of adipokines and glucose in humans. J Clin Endocrinol Metab (2005) 1.81
The role of adiponectin in cancer: a review of current evidence. Endocr Rev (2012) 1.78
Clinical profile and early surgical complications in the Cornea Donor Study. Cornea (2006) 1.77
Effects of exogenous leptin on satiety and satiation in patients with lipodystrophy and leptin insufficiency. J Clin Endocrinol Metab (2004) 1.73
Leptin and reproduction: a review. Fertil Steril (2002) 1.68
Efficacy and safety of leptin-replacement therapy and possible mechanisms of leptin actions in patients with generalized lipodystrophy. J Clin Endocrinol Metab (2006) 1.68
Body fat mass and macronutrient intake in relation to circulating soluble leptin receptor, free leptin index, adiponectin, and resistin concentrations in healthy humans. J Clin Endocrinol Metab (2003) 1.65
Salutary effects of adiponectin on colon cancer: in vivo and in vitro studies in mice. Gut (2012) 1.65
Leptin reverses nonalcoholic steatohepatitis in patients with severe lipodystrophy. Hepatology (2005) 1.63
Coffee drinking and risk of endometrial cancer--a population-based cohort study. Int J Cancer (2009) 1.63
Rat cytomegalovirus-accelerated transplant vascular sclerosis is reduced with mutation of the chemokine-receptor R33. Am J Transplant (2005) 1.63
Effect of lifestyle modification on adipokine levels in obese subjects with insulin resistance. Obes Res (2003) 1.62
Congenital leptin deficiency due to homozygosity for the Delta133G mutation: report of another case and evaluation of response to four years of leptin therapy. J Clin Endocrinol Metab (2004) 1.61
Circulating adiponectin and expression of adiponectin receptors in human skeletal muscle: associations with metabolic parameters and insulin resistance and regulation by physical training. J Clin Endocrinol Metab (2006) 1.61
Recombinant methionyl human leptin administration to achieve high physiologic or pharmacologic leptin levels does not alter circulating inflammatory marker levels in humans with leptin sufficiency or excess. J Clin Endocrinol Metab (2004) 1.61
Relationship of leptin to bone mineralization in children and adolescents. J Clin Endocrinol Metab (2003) 1.58
Neonatal leptin levels are strongly associated with female gender, birth length, IGF-I levels and formula feeding. Clin Endocrinol (Oxf) (2005) 1.57
Recombinant methionyl human leptin therapy in replacement doses improves insulin resistance and metabolic profile in patients with lipoatrophy and metabolic syndrome induced by the highly active antiretroviral therapy. J Clin Endocrinol Metab (2006) 1.55
Role of leptin in energy-deprivation states: normal human physiology and clinical implications for hypothalamic amenorrhoea and anorexia nervosa. Lancet (2005) 1.55
Sex disparities in the treatment and control of cardiovascular risk factors in type 2 diabetes. Diabetes Care (2008) 1.51
Circulating melanin-concentrating hormone, agouti-related protein, and alpha-melanocyte-stimulating hormone levels in relation to body composition: alterations in response to food deprivation and recombinant human leptin administration. J Clin Endocrinol Metab (2004) 1.51
Long-term metreleptin treatment increases bone mineral density and content at the lumbar spine of lean hypoleptinemic women. Metabolism (2011) 1.51
Total and high-molecular-weight adiponectin in breast cancer: in vitro and in vivo studies. J Clin Endocrinol Metab (2006) 1.47
Differential regulation of metabolic, neuroendocrine, and immune function by leptin in humans. Proc Natl Acad Sci U S A (2006) 1.46
Leptin in human physiology and therapeutics. Front Neuroendocrinol (2010) 1.46
Effect of leptin replacement on brain structure in genetically leptin-deficient adults. J Clin Endocrinol Metab (2005) 1.44
Long-term efficacy of leptin replacement in patients with Dunnigan-type familial partial lipodystrophy. Metabolism (2007) 1.40
Interloop fluid in intussusception: what is its significance? Pediatr Radiol (2011) 1.39
Effects of nebulized bronchodilator therapy on heart rate and arrhythmias in critically ill adult patients. Chest (2011) 1.39
Predictors of Circulating Insulin-Like Growth Factor-1 and Insulin-Like Growth Factor-Binding Protein-3 in Critical Illness. Crit Care Med (2015) 1.38
Diabetes and risk of endometrial cancer: a population-based prospective cohort study. Cancer Epidemiol Biomarkers Prev (2007) 1.37
Irisin mRNA and circulating levels in relation to other myokines in healthy and morbidly obese humans. Eur J Endocrinol (2013) 1.37
Effects of acute and chronic administration of the melanocortin agonist MTII in mice with diet-induced obesity. Diabetes (2002) 1.37
Regulation of circulating soluble leptin receptor levels by gender, adiposity, sex steroids, and leptin: observational and interventional studies in humans. Diabetes (2002) 1.37
Pharmacological concentrations of irisin increase cell proliferation without influencing markers of neurite outgrowth and synaptogenesis in mouse H19-7 hippocampal cell lines. Metabolism (2013) 1.36
Rationale for leptin-replacement therapy for severe lipodystrophy. Endocr Pract (2010) 1.35
Leptin in humans: lessons from translational research. Am J Clin Nutr (2009) 1.35
Lipodystrophy: pathophysiology and advances in treatment. Nat Rev Endocrinol (2010) 1.34
Irisin: a renaissance in metabolism? Metabolism (2013) 1.32
Hypoadiponectinemia is associated with insulin resistance, hypertriglyceridemia, and fat redistribution in human immunodeficiency virus-infected patients treated with highly active antiretroviral therapy. J Clin Endocrinol Metab (2003) 1.32
Serum adiponectin concentrations and tissue expression of adiponectin receptors are reduced in patients with prostate cancer: a case control study. Cancer Epidemiol Biomarkers Prev (2007) 1.31
Adiponectin genetic variability, plasma adiponectin, and cardiovascular risk in patients with type 2 diabetes. Diabetes (2006) 1.29
Phase II study of androgen synthesis inhibition with ketoconazole, hydrocortisone, and dutasteride in asymptomatic castration-resistant prostate cancer. Clin Cancer Res (2009) 1.29
Recombinant osteoprotegerin for juvenile Paget's disease. N Engl J Med (2005) 1.27
Regulation of adiponectin and its receptors in response to development of diet-induced obesity in mice. Am J Physiol Endocrinol Metab (2006) 1.27
Adherence to healthy eating patterns is associated with higher circulating total and high-molecular-weight adiponectin and lower resistin concentrations in women from the Nurses' Health Study. Am J Clin Nutr (2008) 1.27
Insulin resistance and vascular dysfunction in nondiabetic Asian Indians. J Clin Endocrinol Metab (2004) 1.26
Leptin is an effective treatment for hypothalamic amenorrhea. Proc Natl Acad Sci U S A (2011) 1.26
Effect of dieting on plasma leptin, soluble leptin receptor, adiponectin and resistin levels in healthy volunteers. Clin Endocrinol (Oxf) (2004) 1.25
Energy homeostasis, obesity and eating disorders: recent advances in endocrinology. J Nutr (2004) 1.24
Human immunodeficiency virus type 1-related lipoatrophy and lipohypertrophy are associated with serum concentrations of leptin. Clin Infect Dis (2003) 1.24
The policy analysis of 'values talk': lessons from Canadian health reform. Health Policy (2004) 1.23
Genetic variability at the leptin receptor (LEPR) locus is a determinant of plasma fibrinogen and C-reactive protein levels. Atherosclerosis (2006) 1.22
Adiponectin: a link between obesity and cancer. Expert Opin Investig Drugs (2006) 1.20