Published in EMBO J on June 01, 1992
Site-specific analysis of protein S-acylation by resin-assisted capture. J Lipid Res (2010) 1.77
A novel N-terminal motif for palmitoylation of G-protein alpha subunits. Biochem J (1993) 1.57
GAIP is membrane-anchored by palmitoylation and interacts with the activated (GTP-bound) form of G alpha i subunits. Proc Natl Acad Sci U S A (1996) 1.48
Plasma membrane localization is required for RGS4 function in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1998) 1.46
Human palmitoyl protein thioesterase: evidence for lysosomal targeting of the enzyme and disturbed cellular routing in infantile neuronal ceroid lipofuscinosis. EMBO J (1996) 1.24
Regulation of dendritic branching and filopodia formation in hippocampal neurons by specific acylated protein motifs. Mol Biol Cell (2004) 1.23
Altered phosphorylation and desensitization patterns of a human beta 2-adrenergic receptor lacking the palmitoylated Cys341. EMBO J (1993) 1.18
Palmitoylation of either Cys-3 or Cys-5 is required for the biological activity of the Lck tyrosine protein kinase. Mol Cell Biol (1995) 1.17
Absence of persistent spreading, branching, and adhesion in GAP-43-depleted growth cones. J Cell Biol (1995) 1.15
Depletion of 43-kD growth-associated protein in primary sensory neurons leads to diminished formation and spreading of growth cones. J Cell Biol (1993) 1.11
Lipid-modified, cysteinyl-containing peptides of diverse structures are efficiently S-acylated at the plasma membrane of mammalian cells. J Cell Biol (1996) 1.09
Cytoplasmic tail length influences fatty acid selection for acylation of viral glycoproteins. Biochem J (1996) 1.04
Posttranslational modification of tubulin by palmitoylation: I. In vivo and cell-free studies. Mol Biol Cell (1997) 0.98
GAP-43 augments G protein-coupled receptor transduction in Xenopus laevis oocytes. Proc Natl Acad Sci U S A (1993) 0.96
Autopalmitoylation of tubulin. Protein Sci (2000) 0.80
Exocytosis in single chromaffin cells: regulation by a secretory granule-associated Go protein. Cell Mol Neurobiol (1997) 0.80
B-50/GAP-43-induced formation of filopodia depends on Rho-GTPase. Mol Biol Cell (1998) 0.79
E2F8 is a nonreceptor activator of heterotrimeric G proteins. J Mol Signal (2007) 0.77
Evidence for multisite ADP-ribosylation of neuronal phosphoprotein B-50/GAP-43. Mol Cell Biochem (1996) 0.77
Use of micellar electrokinetic chromatography to measure palmitoylation of a peptide. J Chromatogr B Analyt Technol Biomed Life Sci (2008) 0.75
Distinct palmitoylation events at the amino-terminal conserved cysteines of Env7 direct its stability, localization, and vacuolar fusion regulation in S. cerevisiae. J Biol Chem (2014) 0.75
All ras proteins are polyisoprenylated but only some are palmitoylated. Cell (1989) 9.68
Purification and properties of the inhibitory guanine nucleotide regulatory unit of brain adenylate cyclase. J Biol Chem (1984) 3.82
Prenyl proteins in eukaryotic cells: a new type of membrane anchor. Trends Biochem Sci (1990) 3.12
The covalent modification of eukaryotic proteins with lipid. J Cell Biol (1987) 3.00
Dynamic fatty acylation of p21N-ras. EMBO J (1987) 2.99
Palmitoylation of the human beta 2-adrenergic receptor. Mutation of Cys341 in the carboxyl tail leads to an uncoupled nonpalmitoylated form of the receptor. J Biol Chem (1989) 2.95
Fatty acylation of proteins. Annu Rev Cell Biol (1988) 2.92
Axonal growth-associated proteins. Annu Rev Neurosci (1989) 2.76
Posttranslational modification of proteins by isoprenoids in mammalian cells. FASEB J (1990) 2.17
Posttranslational membrane attachment and dynamic fatty acylation of a neuronal growth cone protein, GAP-43. J Cell Biol (1989) 2.14
Growth-associated protein, GAP-43, a polypeptide that is induced when neurons extend axons, is a component of growth cones and corresponds to pp46, a major polypeptide of a subcellular fraction enriched in growth cones. Proc Natl Acad Sci U S A (1986) 1.85
Morphoregulatory activities of NCAM and N-cadherin can be accounted for by G protein-dependent activation of L- and N-type neuronal Ca2+ channels. Cell (1991) 1.85
The influence of bound GDP on the kinetics of guanine nucleotide binding to G proteins. J Biol Chem (1986) 1.83
Regulation of growth cone behavior by calcium. J Neurosci (1991) 1.81
The mammalian beta 2-adrenergic receptor: reconstitution of functional interactions between pure receptor and pure stimulatory nucleotide binding protein of the adenylate cyclase system. Biochemistry (1984) 1.77
G0 is a major growth cone protein subject to regulation by GAP-43. Nature (1990) 1.72
A protein induced during nerve growth (GAP-43) is a major component of growth-cone membranes. Science (1986) 1.60
Axonally transported proteins associated with axon growth in rabbit central and peripheral nervous systems. J Cell Biol (1981) 1.58
Cloning of complementary DNA for GAP-43, a neuronal growth-related protein. Science (1987) 1.57
A membrane-targeting signal in the amino terminus of the neuronal protein GAP-43. Nature (1989) 1.49
Characterization of the calmodulin binding domain of neuromodulin. Functional significance of serine 41 and phenylalanine 42. J Biol Chem (1991) 1.41
Acylation of disc membrane rhodopsin may be nonenzymatic. J Biol Chem (1987) 1.25
Inhibition of the receptor-mediated endocytosis of diferric transferrin is associated with the covalent modification of the transferrin receptor with palmitic acid. J Biol Chem (1990) 1.23
Mechanisms of muscarinic receptor action on Go in reconstituted phospholipid vesicles. J Biol Chem (1989) 1.21
Cell-free fatty acid acylation of Semliki Forest viral polypeptides with microsomal membranes from eukaryotic cells. J Biol Chem (1984) 1.21
The neuronal growth-associated protein GAP-43 induces filopodia in non-neuronal cells. Science (1989) 1.19
Ankyrin is fatty acid acylated in erythrocytes. Proc Natl Acad Sci U S A (1986) 1.19
Inhibition of noradrenaline release by antibodies to B-50 (GAP-43). Nature (1989) 1.09
Characterization of an acyltransferase acting on p21N-ras protein in a cell-free system. Biochim Biophys Acta (1991) 1.09
A selective increase in phosporylation of protein F1, a protein kinase C substrate, directly related to three day growth of long term synaptic enhancement. Brain Res (1985) 1.06
Phospholipid-mediated delivery of anti-GAP-43 antibodies into neuroblastoma cells prevents neuritogenesis. J Neurosci (1991) 0.99
Nonacylated human transferrin receptors are rapidly internalized and mediate iron uptake. J Biol Chem (1990) 0.97
Increased transport of 44,000- to 49,000-dalton acidic proteins during regeneration of the goldfish optic nerve: a two-dimensional gel analysis. J Neurosci (1983) 0.97
Targeting of neuromodulin (GAP-43) fusion proteins to growth cones in cultured rat embryonic neurons. Neuron (1991) 0.96
Fatty acids covalently bound to erythrocyte proteins undergo a differential turnover in vivo. J Biol Chem (1988) 0.96
An intracellular guanine nucleotide release protein for G0. GAP-43 stimulates isolated alpha subunits by a novel mechanism. J Biol Chem (1991) 0.93
Identification of a novel fatty acylated protein that partitions between the plasma membrane and cytosol and is deacylated in response to serum and growth factor stimulation. J Biol Chem (1989) 0.92
Characterization of mucus glycoprotein fatty acyltransferase from gastric mucosa. J Biol Chem (1984) 0.90
Autoacylation of myelin proteolipid protein with acyl coenzyme A. J Biol Chem (1987) 0.89
The neuronal growth cone as a specialized transduction system. Bioessays (1991) 0.89
Sm25, a major schistosome tegumental glycoprotein, is dependent on palmitic acid for membrane attachment. EMBO J (1991) 0.88
Resolution of rat brain synaptic phosphoprotein B-50 into multiple forms by two-dimensional electrophoresis: evidence for multisite phosphorylation. J Neurochem (1985) 0.86
Protein fatty acyltransferase is located in the rough endoplasmic reticulum. FEBS Lett (1985) 0.86
Hydrophobic modifications of membrane proteins by palmitoylation in vitro. Biochem Soc Trans (1989) 0.85
Cell-free fatty acylation of microsomal integrated and detergent-solubilized glycoprotein of vesicular stomatitis virus. J Biol Chem (1987) 0.82
Agonist-enhanced palmitoylation of platelet proteins. Biochim Biophys Acta (1989) 0.81
Insulin stimulates fatty acid acylation of adipocyte proteins. Biochem Biophys Res Commun (1991) 0.77
Hypertension in mice lacking the gene for endothelial nitric oxide synthase. Nature (1995) 9.86
Nitric oxide synthase modulates angiogenesis in response to tissue ischemia. J Clin Invest (1998) 5.95
Effects of cerebral ischemia in mice deficient in neuronal nitric oxide synthase. Science (1994) 5.15
Targeted disruption of the neuronal nitric oxide synthase gene. Cell (1993) 5.02
Identification of a receptor mediating Nogo-66 inhibition of axonal regeneration. Nature (2001) 4.96
Identification of the Nogo inhibitor of axon regeneration as a Reticulon protein. Nature (2000) 4.30
Prevention of vertebrate neuronal death by the crmA gene. Science (1994) 4.09
Plexin-neuropilin-1 complexes form functional semaphorin-3A receptors. Cell (1999) 3.84
Mutations affecting the formation and function of the cardiovascular system in the zebrafish embryo. Development (1996) 3.63
Gridlock, a localized heritable vascular patterning defect in the zebrafish. Nat Med (1995) 3.59
Zebrafish genetic map with 2000 microsatellite markers. Genomics (1999) 3.56
LRRTM1 on chromosome 2p12 is a maternally suppressed gene that is associated paternally with handedness and schizophrenia. Mol Psychiatry (2007) 3.49
Impaired defense of intestinal mucosa in mice lacking intestinal trefoil factor. Science (1996) 3.32
Gridlock signalling pathway fashions the first embryonic artery. Nature (2001) 3.30
Behavioural abnormalities in male mice lacking neuronal nitric oxide synthase. Nature (1995) 3.15
Early development of the zebrafish pronephros and analysis of mutations affecting pronephric function. Development (1998) 3.07
A microsatellite genetic linkage map for zebrafish (Danio rerio). Nat Genet (1998) 3.06
Cloche, an early acting zebrafish gene, is required by both the endothelial and hematopoietic lineages. Development (1995) 3.05
Semaphorin III is needed for normal patterning and growth of nerves, bones and heart. Nature (1996) 2.94
gridlock, an HLH gene required for assembly of the aorta in zebrafish. Science (2000) 2.90
Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6 -tetrahydropyridine: uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity. Proc Natl Acad Sci U S A (1985) 2.85
Collapsin-induced growth cone collapse mediated by an intracellular protein related to UNC-33. Nature (1995) 2.78
Enlarged infarcts in endothelial nitric oxide synthase knockout mice are attenuated by nitro-L-arginine. J Cereb Blood Flow Metab (1996) 2.78
Potassium current suppression by quinidine reveals additional calcium currents in neuroblastoma cells. Proc Natl Acad Sci U S A (1981) 2.45
Functional expression of sodium channel mutations identified in families with periodic paralysis. Neuron (1993) 2.44
Hematopoietic mutations in the zebrafish. Development (1996) 2.25
Semaphorins A and E act as antagonists of neuropilin-1 and agonists of neuropilin-2 receptors. Nat Neurosci (1998) 2.16
Zebrafish tinman homolog demarcates the heart field and initiates myocardial differentiation. Development (1996) 2.12
Reduced brain edema and infarction volume in mice lacking the neuronal isoform of nitric oxide synthase after transient MCA occlusion. J Cereb Blood Flow Metab (1996) 2.01
Vessel patterning in the embryo of the zebrafish: guidance by notochord. Dev Biol (1997) 1.99
Neuropilin-1 extracellular domains mediate semaphorin D/III-induced growth cone collapse. Neuron (1998) 1.96
Expression of a dominant negative mutant of interleukin-1 beta converting enzyme in transgenic mice prevents neuronal cell death induced by trophic factor withdrawal and ischemic brain injury. J Exp Med (1997) 1.89
Cardiovascular development in the zebrafish. I. Myocardial fate map and heart tube formation. Development (1993) 1.85
Left-right pattern of cardiac BMP4 may drive asymmetry of the heart in zebrafish. Development (1997) 1.84
Plexina1 autoinhibition by the plexin sema domain. Neuron (2001) 1.81
Rac1 mediates collapsin-1-induced growth cone collapse. J Neurosci (1997) 1.79
G0 is a major growth cone protein subject to regulation by GAP-43. Nature (1990) 1.72
Neuronal pathfinding is abnormal in mice lacking the neuronal growth cone protein GAP-43. Cell (1995) 1.71
A reference cross DNA panel for zebrafish (Danio rerio) anchored with simple sequence length polymorphisms. Development (1996) 1.67
Interaction of genetic deficiency of endothelial nitric oxide, gender, and pregnancy in vascular response to injury in mice. J Clin Invest (1998) 1.65
Growth and function of the embryonic heart depend upon the cardiac-specific L-type calcium channel alpha1 subunit. Dev Cell (2001) 1.65
A family of rat CRMP genes is differentially expressed in the nervous system. J Neurosci (1996) 1.64
Pulmonary vasoconstriction and hypertension in mice with targeted disruption of the endothelial nitric oxide synthase (NOS 3) gene. Circ Res (1997) 1.63
Long-term potentiation is reduced in mice that are doubly mutant in endothelial and neuronal nitric oxide synthase. Cell (1996) 1.61
Mutations affecting development of zebrafish digestive organs. Development (1996) 1.58
Cloning of complementary DNA for GAP-43, a neuronal growth-related protein. Science (1987) 1.57
Endothelial NOS and the blockade of LTP by NOS inhibitors in mice lacking neuronal NOS. Science (1994) 1.56
P2Y1 purinergic receptors in sensory neurons: contribution to touch-induced impulse generation. Proc Natl Acad Sci U S A (1996) 1.55
Acetylcholine-induced relaxation in blood vessels from endothelial nitric oxide synthase knockout mice. Br J Pharmacol (1999) 1.54
Semaphorin3A enhances endocytosis at sites of receptor-F-actin colocalization during growth cone collapse. J Cell Biol (2000) 1.53
Partitioning of tissue expression accompanies multiple duplications of the Na+/K+ ATPase alpha subunit gene. Genome Res (2001) 1.50
A membrane-targeting signal in the amino terminus of the neuronal protein GAP-43. Nature (1989) 1.49
G alpha(o) is necessary for muscarinic regulation of Ca2+ channels in mouse heart. Proc Natl Acad Sci U S A (1997) 1.48
Autoradiographic visualization of angiotensin-converting enzyme in rat brain with [3H]captopril: localization to a striatonigral pathway. Proc Natl Acad Sci U S A (1984) 1.44
Pre-pattern in the pronephric kidney field of zebrafish. Development (2001) 1.43
The first highly potent and selective non-peptide neuropeptide Y Y1 receptor antagonist: BIBP3226. Eur J Pharmacol (1994) 1.43
Molecular basis of semaphorin-mediated axon guidance. J Neurobiol (2000) 1.43
Monoclonal antibody production by receptor-mediated electrically induced cell fusion. Nature (1984) 1.42
Biosynthesis of the lantibiotic Pep5. Isolation and characterization of a prepeptide containing dehydroamino acids. Eur J Biochem (1990) 1.40
Action of derivatives of mu-conotoxin GIIIA on sodium channels. Single amino acid substitutions in the toxin separately affect association and dissociation rates. Biochemistry (1992) 1.39
Single amino acid changes that render human IFN-alpha 2 biologically active on mouse cells. EMBO J (1987) 1.37
Neuronal traits of clonal cell lines derived by fusion of dorsal root ganglia neurons with neuroblastoma cells. Proc Natl Acad Sci U S A (1985) 1.36
Neuronal constitutive nitric oxide synthase is involved in murine enteric inhibitory neurotransmission. J Clin Invest (1996) 1.35
Isolation and characterization of an olfactory receptor protein for odorant pyrazines. Proc Natl Acad Sci U S A (1985) 1.34
Brain CRMP forms heterotetramers similar to liver dihydropyrimidinase. J Neurochem (1997) 1.33
Defective "pacemaker" current (Ih) in a zebrafish mutant with a slow heart rate. Proc Natl Acad Sci U S A (1997) 1.30
Termination of transcription by Escherichia coli RNA polymerase: influence of secondary structure of RNA transcripts on rho-independent and rho-dependent termination. Proc Natl Acad Sci U S A (1979) 1.29
Regulation in the heart field of zebrafish. Development (1998) 1.29
A gene defect that causes conduction system disease and dilated cardiomyopathy maps to chromosome 1p1-1q1. Nat Genet (1994) 1.28
Convergence of distinct pathways to heart patterning revealed by the small molecule concentramide and the mutation heart-and-soul. Curr Biol (2001) 1.27
A long purine-pyrimidine homopolymer acts as a transcriptional diode. J Biol Chem (1995) 1.27
ACh dilates pial arterioles in endothelial and neuronal NOS knockout mice by NO-dependent mechanisms. Am J Physiol (1996) 1.26
A PDZ protein regulates the distribution of the transmembrane semaphorin, M-SemF. J Biol Chem (1999) 1.26
Modulation of mouse cardiac function in vivo by eNOS and ANP. Am J Physiol Heart Circ Physiol (2000) 1.25
ESAG 6 and 7 products of Trypanosoma brucei form a transferrin binding protein complex. Eur J Cell Biol (1994) 1.25
Patterning the zebrafish heart tube: acquisition of anteroposterior polarity. Dev Biol (1992) 1.24
Muscarinic cholinergic regulation of cardiac myocyte ICa-L is absent in mice with targeted disruption of endothelial nitric oxide synthase. Proc Natl Acad Sci U S A (1998) 1.23
Genetics of heart development. Trends Genet (2000) 1.23
Calcium extrusion is critical for cardiac morphogenesis and rhythm in embryonic zebrafish hearts. Proc Natl Acad Sci U S A (2005) 1.21
Endogenous digitalis-like activity in mammalian brain. Proc Natl Acad Sci U S A (1979) 1.21
The neuronal growth-associated protein GAP-43 induces filopodia in non-neuronal cells. Science (1989) 1.19
Repulsive factors and axon regeneration in the CNS. Curr Opin Neurobiol (2001) 1.19
Semaphorin-mediated axonal guidance via Rho-related G proteins. Curr Opin Cell Biol (2001) 1.18
Oxygen chemoreception by carotid body cells in culture. Proc Natl Acad Sci U S A (1985) 1.17
Neuronal cell surface molecules mediate specific binding to rabies virus glycoprotein expressed by a recombinant baculovirus on the surfaces of lepidopteran cells. J Virol (1998) 1.14
Neurochemical characteristics of a novel dorsal root ganglion X neuroblastoma hybrid cell line, F-11. J Neurochem (1987) 1.14
The slow mo mutation reduces pacemaker current and heart rate in adult zebrafish. Am J Physiol Heart Circ Physiol (2001) 1.14
The current state-of-the-art of spinal cord imaging: applications. Neuroimage (2013) 1.13
Cardiovascular development in the zebrafish. II. Endocardial progenitors are sequestered within the heart field. Development (1994) 1.12
The current state-of-the-art of spinal cord imaging: methods. Neuroimage (2013) 1.12
Zebrafish dracula encodes ferrochelatase and its mutation provides a model for erythropoietic protoporphyria. Curr Biol (2000) 1.09
Morphogenesis of prechordal plate and notochord requires intact Eph/ephrin B signaling. Dev Biol (2001) 1.08
Cyclooxygenase-2 mediates increased renal renin content induced by low-sodium diet. Hypertension (1997) 1.07
A fast and inexpensive method for N-terminal fluorescein-labeling of peptides. Bioorg Med Chem Lett (1998) 1.07
Molecular characterization of the ligand-receptor interaction of the neuropeptide Y family. J Pept Sci (2000) 1.07
Regional cerebral blood flow response to vibrissal stimulation in mice lacking type I NOS gene expression. Am J Physiol (1996) 1.07
Sir Henry Hallett Dale and acetylcholine story. Yale J Biol Med (1972) 1.07
Structure and dynamics of micelle-bound neuropeptide Y: comparison with unligated NPY and implications for receptor selection. J Mol Biol (2001) 1.06