Published in J Mol Biol on October 22, 2004
Optimization of a GCaMP calcium indicator for neural activity imaging. J Neurosci (2012) 6.09
Rational design of new binding specificity by simultaneous mutagenesis of calmodulin and a target peptide. Biochemistry (2006) 0.96
Using metadynamics to understand the mechanism of calmodulin/target recognition at atomic detail. Biophys J (2006) 0.91
Salt enhances calmodulin-target interaction. Biophys J (2006) 0.88
Adaptable hydrogel networks with reversible linkages for tissue engineering. Adv Mater (2015) 0.85
Contribution of the KCa3.1 channel-calmodulin interactions to the regulation of the KCa3.1 gating process. J Gen Physiol (2013) 0.84
Single-molecule force spectroscopy distinguishes target binding modes of calmodulin. Proc Natl Acad Sci U S A (2009) 0.83
Electrostatic control of the overall shape of calmodulin: numerical calculations. Eur Biophys J (2007) 0.81
Two distinct calmodulin binding sites in the third intracellular loop and carboxyl tail of angiotensin II (AT(1A)) receptor. PLoS One (2013) 0.78
A strategy to identify linker-based modules for the allosteric regulation of antibody-antigen binding affinities of different scFvs. MAbs (2017) 0.75
Peroxiredoxins. Biol Chem (2002) 3.61
Public knowledge of benefits of breast and prostate cancer screening in Europe. J Natl Cancer Inst (2009) 3.45
Phosphorylation of serine 468 by GSK-3beta negatively regulates basal p65 NF-kappaB activity. J Biol Chem (2004) 2.29
Argyrin a reveals a critical role for the tumor suppressor protein p27(kip1) in mediating antitumor activities in response to proteasome inhibition. Cancer Cell (2008) 2.12
ProteomeBinders: planning a European resource of affinity reagents for analysis of the human proteome. Nat Methods (2007) 2.04
IRSp53 links the enterohemorrhagic E. coli effectors Tir and EspFU for actin pedestal formation. Cell Host Microbe (2009) 2.01
Structure of the molybdopterin-bound Cnx1G domain links molybdenum and copper metabolism. Nature (2004) 1.81
Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle. EMBO J (2004) 1.73
Identification of a novel plasmin(ogen)-binding motif in surface displayed alpha-enolase of Streptococcus pneumoniae. Mol Microbiol (2003) 1.72
Mapping and consensus sequence identification for multiple vinculin binding sites within the talin rod. J Biol Chem (2005) 1.68
The Rho-associated protein kinase p160ROCK is required for centrosome positioning. J Cell Biol (2002) 1.65
A fibrinogen receptor from group B Streptococcus interacts with fibrinogen by repetitive units with novel ligand binding sites. Mol Microbiol (2002) 1.52
Peptide-mediated interference with influenza A virus polymerase. J Virol (2007) 1.48
An arginine/lysine-rich motif is crucial for VCP/p97-mediated modulation of ataxin-3 fibrillogenesis. EMBO J (2006) 1.45
PI3K/Akt is required for heat shock proteins to protect hypoxia-inducible factor 1alpha from pVHL-independent degradation. J Biol Chem (2004) 1.25
Ectodomains 3 and 4 of human polymeric Immunoglobulin receptor (hpIgR) mediate invasion of Streptococcus pneumoniae into the epithelium. J Biol Chem (2003) 1.23
Identification of a PA-binding peptide with inhibitory activity against influenza A and B virus replication. PLoS One (2009) 1.13
Identification of hot regions of the Abeta-IAPP interaction interface as high-affinity binding sites in both cross- and self-association. Angew Chem Int Ed Engl (2010) 1.13
Conformational restraints and flexibility of 14-meric peptides in complex with HLA-B*3501. J Immunol (2004) 1.12
Hepatitis C virus complete life cycle screen for identification of small molecules with pro- or antiviral activity. Antiviral Res (2010) 1.12
A community standard format for the representation of protein affinity reagents. Mol Cell Proteomics (2009) 1.11
Tryparedoxin peroxidase of Leishmania donovani: molecular cloning, heterologous expression, specificity, and catalytic mechanism. Arch Biochem Biophys (2002) 1.11
Inference of genetic regulatory networks with recurrent neural network models using particle swarm optimization. IEEE/ACM Trans Comput Biol Bioinform (2007) 1.11
Minimum information about a protein affinity reagent (MIAPAR). Nat Biotechnol (2010) 1.10
Biochemical and NMR analyses of an SF3b155-p14-U2AF-RNA interaction network involved in branch point definition during pre-mRNA splicing. RNA (2006) 1.09
High-avidity human serum antibodies recognizing linear epitopes of Borna disease virus proteins. Biol Psychiatry (2002) 1.08
Molecular and functional characterization of clathrin- and AP-2-binding determinants within a disordered domain of auxilin. J Biol Chem (2003) 1.08
The granulocyte receptor carcinoembryonic antigen-related cell adhesion molecule 3 (CEACAM3) directly associates with Vav to promote phagocytosis of human pathogens. J Immunol (2007) 1.06
Assessment of toluene/biphenyl dioxygenase gene diversity in benzene-polluted soils: links between benzene biodegradation and genes similar to those encoding isopropylbenzene dioxygenases. Appl Environ Microbiol (2006) 1.06
Immunization of pigs to prevent disease in humans: construction and protective efficacy of a Salmonella enterica serovar Typhimurium live negative-marker vaccine. Infect Immun (2007) 1.04
Kinetics and redox-sensitive oligomerisation reveal negative subunit cooperativity in tryparedoxin peroxidase of Trypanosoma brucei brucei. Biol Chem (2003) 1.04
Pinpointing biphenyl dioxygenase residues that are crucial for substrate interaction. J Bacteriol (2003) 1.04
Melithiazol biosynthesis: further insights into myxobacterial PKS/NRPS systems and evidence for a new subclass of methyl transferases. Chem Biol (2003) 1.04
The interaction of the gammaherpesvirus 68 orf73 protein with cellular BET proteins affects the activation of cell cycle promoters. J Virol (2009) 1.01
Synthesis of sucrose analogues and the mechanism of action of Bacillus subtilis fructosyltransferase (levansucrase). Carbohydr Res (2006) 1.00
Streptococcus pneumoniae enolase is important for plasminogen binding despite low abundance of enolase protein on the bacterial cell surface. Microbiology (2006) 1.00
Identification of high-affinity PB1-derived peptides with enhanced affinity to the PA protein of influenza A virus polymerase. Antimicrob Agents Chemother (2010) 0.99
Suppressor of cytokine signaling 6 associates with KIT and regulates KIT receptor signaling. J Biol Chem (2004) 0.99
14-3-3 proteins are constituents of the insoluble glycoprotein framework of the chlamydomonas cell wall. Plant Cell (2003) 0.99
Identification of a putative Crf splice variant and generation of recombinant antibodies for the specific detection of Aspergillus fumigatus. PLoS One (2009) 0.98
An RGD helper sequence in CagL of Helicobacter pylori assists in interactions with integrins and injection of CagA. Front Cell Infect Microbiol (2012) 0.98
N-terminal myristoylation-dependent masking of neutralizing epitopes in the preS1 attachment site of hepatitis B virus. J Hepatol (2010) 0.97
Calpain mediates a von Hippel-Lindau protein-independent destruction of hypoxia-inducible factor-1alpha. Mol Biol Cell (2006) 0.97
Neurofilaments bind tubulin and modulate its polymerization. J Neurosci (2009) 0.96
Protocadherin 12 (VE-cadherin 2) is expressed in endothelial, trophoblast, and mesangial cells. Exp Cell Res (2005) 0.94
Identification and characterization of the Cdc42-binding site of IQGAP1. Biochem Biophys Res Commun (2003) 0.94
MIF-chemokine receptor interactions in atherogenesis are dependent on an N-loop-based 2-site binding mechanism. FASEB J (2010) 0.92
Borna disease virus matrix protein is an integral component of the viral ribonucleoprotein complex that does not interfere with polymerase activity. J Virol (2006) 0.92
Profiling ubiquitin linkage specificities of deubiquitinating enzymes with branched ubiquitin isopeptide probes. Chembiochem (2012) 0.91
Phosphatidylinositol 3'-kinase activity is critical for initiating the oxidative burst and bacterial destruction during CEACAM3-mediated phagocytosis. J Biol Chem (2011) 0.88
Peptide-mediated disruption of NFkappaB/NRF interaction inhibits IL-8 gene activation by IL-1 or Helicobacter pylori. J Immunol (2007) 0.88
Design of chemical libraries with potentially bioactive molecules applying a maximum common substructure concept. Mol Divers (2009) 0.87
The EAL-like protein STM1697 regulates virulence phenotypes, motility and biofilm formation in Salmonella typhimurium. Mol Microbiol (2013) 0.86
Isolation of scFv fragments specific to OmpD of Salmonella Typhimurium. Vet Microbiol (2010) 0.86
Phase 1 trial of allogeneic gene-modified tumor cell vaccine RCC-26/CD80/IL-2 in patients with metastatic renal cell carcinoma. Hum Gene Ther (2010) 0.85
High immune response rates and decreased frequencies of regulatory T cells in metastatic renal cell carcinoma patients after tumor cell vaccination. Mol Med (2013) 0.84
Substrate specificity of the acyl transferase domains of EpoC from the epothilone polyketide synthase. Org Biomol Chem (2007) 0.84
Large-scale analysis of protein-protein interactions using cellulose-bound peptide arrays. Adv Biochem Eng Biotechnol (2008) 0.84
Rational engineering of the regioselectivity of TecA tetrachlorobenzene dioxygenase for the transformation of chlorinated toluenes. Microbiology (2003) 0.84
Design of a general-purpose European compound screening library for EU-OPENSCREEN. ChemMedChem (2014) 0.83
Myxobacteria: natural pharmaceutical factories. Microb Cell Fact (2012) 0.83
Exploring the mechanisms of vascular smooth muscle tone with highly specific, membrane-permeable inhibitors of cyclic GMP-dependent protein kinase Ialpha. Pharmacol Ther (2002) 0.83
Difference in kinetic behaviour of catechol 2,3-dioxygenase variants from a polluted environment. Microbiology (2004) 0.83
trans-Dienelactone hydrolase from Pseudomonas reinekei MT1, a novel zinc-dependent hydrolase. Biochem Biophys Res Commun (2008) 0.83
The negative regulator of Borna disease virus polymerase is a non-structural protein. J Gen Virol (2005) 0.82
Tryparedoxin and tryparedoxin peroxidase. Methods Enzymol (2002) 0.82
Epitope mapping of pathogenic Leptospira LipL32. Lett Appl Microbiol (2009) 0.82
JKTBP1 is involved in stabilization and IRES-dependent translation of NRF mRNAs by binding to 5' and 3' untranslated regions. J Mol Biol (2011) 0.81
Involvement of conserved asparagine and arginine residues from the N-terminal region in the catalytic mechanism of rat liver and Trypanosoma cruzi tyrosine aminotransferases. Protein Sci (2003) 0.81
Differential effects of multiplicity of infection on Helicobacter pylori-induced signaling pathways and interleukin-8 gene transcription. J Clin Immunol (2010) 0.81
Addition of the immunostimulatory oligonucleotide IMT504 to a seasonal flu vaccine increases hemagglutinin antibody titers in young adult and elder rats, and expands the anti-hemagglutinin antibody repertoire. Nucleic Acid Ther (2011) 0.81
Analysis of protein interactions with immobilized Peptide arrays synthesized on membrane supports. CSH Protoc (2006) 0.81
The surface-associated elongation factor Tu is concealed for antibody binding on viable pneumococci and meningococci. FEMS Immunol Med Microbiol (2008) 0.81
Systematic peptide array-based delineation of the differential beta-catenin interaction with Tcf4, E-cadherin, and adenomatous polyposis coli. J Biol Chem (2004) 0.80
NMR studies of the interaction of tryparedoxin with redox-inactive substrate homologues. Biochemistry (2003) 0.80
Epitope-targeted proteome analysis: towards a large-scale automated protein-protein-interaction mapping utilizing synthetic peptide arrays. Anal Bioanal Chem (2003) 0.80
Disruption of the viral polymerase complex assembly as a novel approach to attenuate influenza A virus. J Biol Chem (2010) 0.80
Symptom recognition of heart attack and stroke in nine European countries: a representative survey. Health Expect (2012) 0.80
The active site of the molybdenum cofactor biosynthetic protein domain Cnx1G. Arch Biochem Biophys (2003) 0.78
Systematic epitope analysis of the p26 EIAV core protein. J Mol Recognit (2007) 0.78
Novel human recombinant antibodies against Mycobacterium tuberculosis antigen 85B. BMC Biotechnol (2014) 0.78
Identification of myxobacteria-derived HIV inhibitors by a high-throughput two-step infectivity assay. Microb Cell Fact (2013) 0.78
The chaotrope-soluble glycoprotein GP2 is a precursor of the insoluble glycoprotein framework of the Chlamydomonas cell wall. J Biol Chem (2007) 0.78
Mapping of NRF binding motifs of NF-kappaB p65 subunit. J Biochem (2011) 0.78
Ganglioside GM1-binding peptides as adjuvants of antigens inoculated by the intranasal route. Vaccine (2005) 0.77
The myxobacterial metabolite ratjadone A inhibits HIV infection by blocking the Rev/CRM1-mediated nuclear export pathway. Microb Cell Fact (2014) 0.77
Synthesis and biological characterization of argyrin F. ChemMedChem (2010) 0.77
Grb14 is a negative regulator of CEACAM3-mediated phagocytosis of pathogenic bacteria. J Biol Chem (2012) 0.77
The myxobacterial compounds spirangien a and spirangien M522 are potent inhibitors of IL-8 expression. Chembiochem (2012) 0.77
Identification of structural determinants for substrate binding and turnover by glucosyltransferase R supports the permutation hypothesis. FEBS Lett (2007) 0.77
Synthesis of cyclic peptides and peptide libraries on a new disulfide linker. J Pept Sci (2007) 0.77
The Saccharomyces cerevisiae ubiquitin E3 ligase Asr1p targets calmodulin for ubiquitylation. Biochem Biophys Res Commun (2011) 0.75
Generation of the heterodimeric precursor GP3 of the Chlamydomonas cell wall. Mol Microbiol (2010) 0.75
Multiplexed sorting of libraries on libraries: a novel method for empirical protein design by affinity-driven phage enrichment on synthetic peptide arrays. Mol Divers (2004) 0.75
Identification of immunodominant regions of Brassica juncea glyoxalase I as potential antitumor immunomodulation targets. Peptides (2005) 0.75
Characterization of the interaction between heterodimeric αvβ6 integrin and urokinase plasminogen activator receptor (uPAR) using functional proteomics. J Proteome Res (2014) 0.75
1H, 15N and 13C resonance assignments and secondary structure of tryparedoxin-I from Crithidia fasciculata. J Biomol NMR (2002) 0.75