Splenic stroma drives mature dendritic cells to differentiate into regulatory dendritic cells.

PubWeight™: 3.25‹?› | Rank: Top 1%

🔗 View Article (PMID 15475957)

Published in Nat Immunol on October 10, 2004

Authors

Minghui Zhang1, Hua Tang, Zhenhong Guo, Huazhang An, Xuejun Zhu, Wengang Song, Jun Guo, Xin Huang, Taoyong Chen, Jianli Wang, Xuetao Cao

Author Affiliations

1: The Institute of Immunology, Second Military Medical University, Shanghai, China.

Articles citing this

Immunosuppressive strategies that are mediated by tumor cells. Annu Rev Immunol (2007) 8.31

Monocytes give rise to mucosal, but not splenic, conventional dendritic cells. J Exp Med (2006) 4.91

Small intestinal CD103+ dendritic cells display unique functional properties that are conserved between mice and humans. J Exp Med (2008) 3.74

The dermis contains langerin+ dendritic cells that develop and function independently of epidermal Langerhans cells. J Exp Med (2007) 3.24

Retracted Foxp3-positive macrophages display immunosuppressive properties and promote tumor growth. J Exp Med (2011) 3.15

E-cadherin marks a subset of inflammatory dendritic cells that promote T cell-mediated colitis. Immunity (2010) 2.78

Integrin CD11b negatively regulates TLR-triggered inflammatory responses by activating Syk and promoting degradation of MyD88 and TRIF via Cbl-b. Nat Immunol (2010) 2.58

Tolerogenic signals delivered by dendritic cells to T cells through a galectin-1-driven immunoregulatory circuit involving interleukin 27 and interleukin 10. Nat Immunol (2009) 2.23

Dendritic cell control of tolerogenic responses. Immunol Rev (2011) 2.13

Hepatic microenvironment programs hematopoietic progenitor differentiation into regulatory dendritic cells, maintaining liver tolerance. Blood (2008) 2.02

Programmed death-1 upregulation is correlated with dysfunction of tumor-infiltrating CD8+ T lymphocytes in human non-small cell lung cancer. Cell Mol Immunol (2010) 2.01

Tumor-infiltrating regulatory dendritic cells inhibit CD8+ T cell function via L-arginine metabolism. Cancer Res (2009) 1.99

Dendritic cells in intestinal homeostasis and disease. J Clin Invest (2009) 1.83

Division of labor, plasticity, and crosstalk between dendritic cell subsets. Curr Opin Immunol (2007) 1.70

Immunosenescence and macrophage functional plasticity: dysregulation of macrophage function by age-associated microenvironmental changes. Immunol Rev (2005) 1.64

Regulation of lymph node vascular growth by dendritic cells. J Exp Med (2006) 1.62

Immune mechanisms in medium and large-vessel vasculitis. Nat Rev Rheumatol (2013) 1.48

CSF-1 receptor-mediated differentiation of a new type of monocytic cell with B cell-stimulating activity: its selective dependence on IL-34. J Leukoc Biol (2013) 1.47

Fibroblasts as novel therapeutic targets in chronic inflammation. Br J Pharmacol (2007) 1.45

Stromal and hematopoietic cells in secondary lymphoid organs: partners in immunity. Immunol Rev (2013) 1.40

CD11b facilitates the development of peripheral tolerance by suppressing Th17 differentiation. J Exp Med (2007) 1.40

Autoimmune arthritis associated with mutated interleukin (IL)-6 receptor gp130 is driven by STAT3/IL-7-dependent homeostatic proliferation of CD4+ T cells. J Exp Med (2006) 1.39

Mesenchymal stem cells: Emerging mechanisms of immunomodulation and therapy. World J Stem Cells (2014) 1.29

Dendritic cells and tumor microenvironment: a dangerous liaison. Immunol Invest (2006) 1.26

Regulation of dendritic-cell differentiation by bone marrow stroma via different Notch ligands. Blood (2006) 1.25

CD11c+CD11b+ dendritic cells play an important role in intravenous tolerance and the suppression of experimental autoimmune encephalomyelitis. J Immunol (2008) 1.24

Immune interactions in hepatic fibrosis. Clin Liver Dis (2008) 1.23

Stromal-mediated protection of tyrosine kinase inhibitor-treated BCR-ABL-expressing leukemia cells. Mol Cancer Ther (2008) 1.23

Fibroblastic reticular cells from lymph nodes attenuate T cell expansion by producing nitric oxide. PLoS One (2011) 1.20

Dendritic cells: arbiters of immunity and immunological tolerance. Cold Spring Harb Perspect Biol (2012) 1.20

Dendritic cell quiescence during systemic inflammation driven by LPS stimulation of radioresistant cells in vivo. J Exp Med (2007) 1.10

Gamma-ray irradiation impairs dendritic cell migration to CCL19 by down-regulation of CCR7 and induction of cell apoptosis. Int J Biol Sci (2011) 1.09

Personalized dendritic cell-based tumor immunotherapy. Immunotherapy (2010) 1.08

Efficient dendritic cell priming of T lymphocytes depends on the extracellular matrix protein mindin. EMBO J (2006) 1.03

Life sciences and biotechnology in China. Philos Trans R Soc Lond B Biol Sci (2007) 1.00

The dendritic cell-regulatory T lymphocyte crosstalk contributes to tumor-induced tolerance. Clin Dev Immunol (2011) 0.99

Identification of a novel antigen cross-presenting cell type in spleen. J Cell Mol Med (2010) 0.98

The immunopathology of liver granulomas in primary biliary cirrhosis. J Autoimmun (2012) 0.98

miRNomes of haematopoietic stem cells and dendritic cells identify miR-30b as a regulator of Notch1. Nat Commun (2013) 0.95

MiR-21 plays an important role in radiation induced carcinogenesis in BALB/c mice by directly targeting the tumor suppressor gene Big-h3. Int J Biol Sci (2011) 0.94

CD1a expression defines an interleukin-12 producing population of human dendritic cells. Clin Exp Immunol (2009) 0.94

Positive and negative regulation of T cell responses by fibroblastic reticular cells within paracortical regions of lymph nodes. Front Immunol (2012) 0.91

Trypanosoma cruzi induces regulatory dendritic cells in vitro. Infect Immun (2008) 0.88

Nitric oxide controls an inflammatory-like Ly6C(hi)PDCA1+ DC subset that regulates Th1 immune responses. J Leukoc Biol (2010) 0.87

Contrasting roles of SPARC-related granuloma in bacterial containment and in the induction of anti-Salmonella typhimurium immunity. J Exp Med (2008) 0.86

Microglia and microglia-like cell differentiated from DC inhibit CD4 T cell proliferation. PLoS One (2009) 0.86

Ex vivo expanded dendritic cells home to T-cell zones of lymphoid organs and survive in vivo after allogeneic bone marrow transplantation. Am J Pathol (2005) 0.86

Low dose zymosan ameliorates both chronic and relapsing experimental autoimmune encephalomyelitis. J Neuroimmunol (2012) 0.85

Fas signal promotes the immunosuppressive function of regulatory dendritic cells via the ERK/β-catenin pathway. J Biol Chem (2013) 0.84

A GMCSF-neuroantigen fusion protein is a potent tolerogen in experimental autoimmune encephalomyelitis (EAE) that is associated with efficient targeting of neuroantigen to APC. J Leukoc Biol (2010) 0.84

Nicotine stimulated dendritic cells could achieve anti-tumor effects in mouse lung and liver cancer. J Clin Immunol (2010) 0.84

TGF-beta1 gene-modified, immature dendritic cells delay the development of inflammatory bowel disease by inducing CD4(+)Foxp3(+) regulatory T cells. Cell Mol Immunol (2010) 0.84

Murine spleen contains a diversity of myeloid and dendritic cells distinct in antigen presenting function. J Cell Mol Med (2012) 0.84

Cell-based interventions to halt autoimmunity in type 1 diabetes mellitus. Clin Exp Immunol (2013) 0.84

Tolerogenic dendritic cells and their applications in transplantation. Cell Mol Immunol (2014) 0.84

Spleen as a site for hematopoiesis of a distinct antigen presenting cell type. Stem Cells Int (2011) 0.83

Murine myeloid dendritic cells that phagocytose apoptotic T cells inhibit the immune response via NO. PLoS One (2012) 0.83

Co-operative action of interleukin-10 and interferon-gamma to regulate dendritic cell functions. Immunology (2008) 0.83

Dendritic cell tumor killing activity and its potential applications in cancer immunotherapy. Crit Rev Immunol (2013) 0.82

Myelopoiesis in spleen-producing distinct dendritic-like cells. J Cell Mol Med (2012) 0.82

TLR4 inactivation protects from graft-versus-host disease after allogeneic hematopoietic stem cell transplantation. Cell Mol Immunol (2012) 0.82

CD8(+)NKT-like cells regulate the immune response by killing antigen-bearing DCs. Sci Rep (2015) 0.81

Influence of the tissue microenvironment on Toll-like receptor expression by CD11c+ antigen-presenting cells isolated from mucosal tissues. Clin Vaccine Immunol (2009) 0.81

Antigen-specific tolerogenic dendritic cells ameliorate the severity of murine collagen-induced arthritis. PLoS One (2015) 0.81

Immunosuppressive mechanisms of regulatory dendritic cells in cancer. Cancer Microenviron (2013) 0.81

Neuroantigen-specific, tolerogenic vaccines: GM-CSF is a fusion partner that facilitates tolerance rather than immunity to dominant self-epitopes of myelin in murine models of experimental autoimmune encephalomyelitis (EAE). BMC Immunol (2011) 0.81

Salmeterol attenuates the inflammatory response in asthma and decreases the pro-inflammatory cytokine secretion of dendritic cells. Cell Mol Immunol (2012) 0.81

Development of two distinct dendritic-like APCs in the context of splenic stroma. Front Immunol (2013) 0.80

Vitronectin in human hepatic tumours contributes to the recruitment of lymphocytes in an alpha v beta3-independent manner. Br J Cancer (2006) 0.79

Lipopolysaccharide and dose of nicotine determine the effects of nicotine on murine bone marrow-derived dendritic cells. Mol Med Rep (2012) 0.79

Twist and miR-34a are involved in the generation of tumor-educated myeloid-derived suppressor cells. Int J Mol Sci (2013) 0.79

Trp53 inactivation in the tumor microenvironment promotes tumor progression by expanding the immunosuppressive lymphoid-like stromal network. Cancer Res (2013) 0.79

Infusion of UVB-treated splenic stromal cells induces suppression of beta cell antigen-specific T cell responses in NOD mice. J Autoimmun (2008) 0.79

Retracted Baicalin induced dendritic cell apoptosis in vitro. Front Pharmacol (2011) 0.79

Stromal cell induction of regulatory dendritic cells. Front Immunol (2012) 0.79

Capacity of lung stroma to educate dendritic cells inhibiting mycobacteria-specific T-cell response depends upon genetic susceptibility to tuberculosis. PLoS One (2013) 0.78

Dendritic cells as immune regulators: the mouse model. J Cell Mol Med (2008) 0.78

Are dendritic cells end cells? Nat Immunol (2004) 0.78

Indoleamine 2,3-dioxygenase and regulatory dendritic cells contribute to the allograft protection induced by infusion of donor-specific splenic stromal cells. Cell Mol Immunol (2010) 0.77

Ex vivo nicotine stimulation augments the efficacy of human peripheral blood mononuclear cell-derived dendritic cell vaccination via activating Akt-S6 pathway. Anal Cell Pathol (Amst) (2015) 0.77

In vivo imaging of therapy-induced anti-cancer immune responses in humans. Cell Mol Life Sci (2012) 0.76

Intratumoral accumulation of podoplanin-expressing lymph node stromal cells promote tumor growth through elimination of CD4(+) tumor-infiltrating lymphocytes. Oncoimmunology (2016) 0.75

Breast regression protein-39 (BRP-39) promotes dendritic cell maturation in vitro and enhances Th2 inflammation in murine model of asthma. Acta Pharmacol Sin (2012) 0.75

Protective effect of Flt3L on organ structure during advanced multiorgan dysfunction syndrome in mice. Mol Med Rep (2015) 0.75

Human lung fibroblasts may modulate dendritic cell phenotype and function: results from a pilot in vitro study. Respir Res (2016) 0.75

Human lung fibroblasts produce proresolving peroxisome proliferator-activated receptor-γ ligands in a cyclooxygenase-2-dependent manner. Am J Physiol Lung Cell Mol Physiol (2016) 0.75

Marsdenia tenacissima extract suppresses tumor growth and angiogenesis in A20 mouse lymphoma. Oncol Lett (2017) 0.75

Stromal Cell Subsets Directing Neonatal Spleen Regeneration. Sci Rep (2017) 0.75

Integrin CD11b attenuates colitis by strengthening Src-Akt pathway to polarize anti-inflammatory IL-10 expression. Sci Rep (2016) 0.75

The Importance of Dendritic Cells in Maintaining Immune Tolerance. J Immunol (2017) 0.75

Articles by these authors

Worldwide human relationships inferred from genome-wide patterns of variation. Science (2008) 22.44

Overall survival and updated results for sunitinib compared with interferon alfa in patients with metastatic renal cell carcinoma. J Clin Oncol (2009) 13.52

Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: a randomised controlled trial. Lancet (2006) 12.98

Personal omics profiling reveals dynamic molecular and medical phenotypes. Cell (2012) 12.32

Pazopanib versus sunitinib in metastatic renal-cell carcinoma. N Engl J Med (2013) 10.74

Expression of epiregulin and amphiregulin and K-ras mutation status predict disease control in metastatic colorectal cancer patients treated with cetuximab. J Clin Oncol (2007) 9.29

The importance of race and ethnic background in biomedical research and clinical practice. N Engl J Med (2003) 7.94

Admixture mapping for hypertension loci with genome-scan markers. Nat Genet (2005) 6.78

Essential role for nuclear PTEN in maintaining chromosomal integrity. Cell (2007) 6.52

Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries, 1990-2013: quantifying the epidemiological transition. Lancet (2015) 6.13

Visualizing metabolically labeled glycoconjugates of living cells by copper-free and fast huisgen cycloadditions. Angew Chem Int Ed Engl (2008) 5.90

Categorization of humans in biomedical research: genes, race and disease. Genome Biol (2002) 4.84

Identification of miRNomes in human liver and hepatocellular carcinoma reveals miR-199a/b-3p as therapeutic target for hepatocellular carcinoma. Cancer Cell (2011) 4.54

Primary and secondary kinase genotypes correlate with the biological and clinical activity of sunitinib in imatinib-resistant gastrointestinal stromal tumor. J Clin Oncol (2008) 4.10

Recruitment and regulation of phosphatidylinositol phosphate kinase type 1 gamma by the FERM domain of talin. Nature (2002) 4.03

Molecular and evolutionary history of melanism in North American gray wolves. Science (2009) 3.87

The microRNA miR-29 controls innate and adaptive immune responses to intracellular bacterial infection by targeting interferon-γ. Nat Immunol (2011) 3.77

MicroRNA-146a feedback inhibits RIG-I-dependent Type I IFN production in macrophages by targeting TRAF6, IRAK1, and IRAK2. J Immunol (2009) 3.72

Wnt signaling in the niche enforces hematopoietic stem cell quiescence and is necessary to preserve self-renewal in vivo. Cell Stem Cell (2008) 3.62

Toll-like receptor-mediated induction of type I interferon in plasmacytoid dendritic cells requires the rapamycin-sensitive PI(3)K-mTOR-p70S6K pathway. Nat Immunol (2008) 3.43

Cross-host evolution of severe acute respiratory syndrome coronavirus in palm civet and human. Proc Natl Acad Sci U S A (2005) 3.37

Activity of sunitinib in patients with advanced neuroendocrine tumors. J Clin Oncol (2008) 3.34

Cancer-expanded myeloid-derived suppressor cells induce anergy of NK cells through membrane-bound TGF-beta 1. J Immunol (2009) 3.27

Expression of Cux-1 and Cux-2 in the subventricular zone and upper layers II-IV of the cerebral cortex. J Comp Neurol (2004) 3.20

Population stratification confounds genetic association studies among Latinos. Hum Genet (2005) 3.19

Intracellular MHC class II molecules promote TLR-triggered innate immune responses by maintaining activation of the kinase Btk. Nat Immunol (2011) 3.12

Genetic admixture and asthma-related phenotypes in Mexican American and Puerto Rican asthmatics. Genet Epidemiol (2005) 3.03

The cytosolic nucleic acid sensor LRRFIP1 mediates the production of type I interferon via a beta-catenin-dependent pathway. Nat Immunol (2010) 2.95

Phosphatase SHP-1 promotes TLR- and RIG-I-activated production of type I interferon by inhibiting the kinase IRAK1. Nat Immunol (2008) 2.89

Changes in choroidal thickness after panretinal photocoagulation in patients with type 2 diabetes. Retina (2015) 2.71

Susceptibility locus for clinical and subclinical coronary artery disease at chromosome 9p21 in the multi-ethnic ADVANCE study. Hum Mol Genet (2008) 2.71

Comparative and functional genomic analyses of the pathogenicity of phytopathogen Xanthomonas campestris pv. campestris. Genome Res (2005) 2.65

The STAT3-binding long noncoding RNA lnc-DC controls human dendritic cell differentiation. Science (2014) 2.63

Integrin CD11b negatively regulates TLR-triggered inflammatory responses by activating Syk and promoting degradation of MyD88 and TRIF via Cbl-b. Nat Immunol (2010) 2.58

Phase II trial of sunitinib in patients with metastatic colorectal cancer after failure of standard therapy. J Clin Oncol (2007) 2.51

MicroRNA-27a functions as an oncogene in gastric adenocarcinoma by targeting prohibitin. Cancer Lett (2008) 2.48

Mesenchymal stem cells: a new strategy for immunosuppression and tissue repair. Cell Res (2010) 2.46

Methylation of SPT5 regulates its interaction with RNA polymerase II and transcriptional elongation properties. Mol Cell (2003) 2.39

First-line treatment of advanced breast cancer with sunitinib in combination with docetaxel versus docetaxel alone: results of a prospective, randomized phase III study. J Clin Oncol (2012) 2.36

Variation and genetic control of protein abundance in humans. Nature (2013) 2.32

Defining the critical hurdles in cancer immunotherapy. J Transl Med (2011) 2.32

The genome and transcriptomes of the anti-tumor agent Clostridium novyi-NT. Nat Biotechnol (2006) 2.31

Sequential phases of cortical specification involve Neurogenin-dependent and -independent pathways. EMBO J (2004) 2.30

Programming dendritic cells to induce T(H)2 and tolerogenic responses. Nat Immunol (2010) 2.29

Genome-wide association study implicates chromosome 9q21.31 as a susceptibility locus for asthma in mexican children. PLoS Genet (2009) 2.27

Leptin exacerbates collagen-induced arthritis via enhancement of Th17 cell response. Arthritis Rheum (2012) 2.26

Somatic mutation and gain of copy number of PIK3CA in human breast cancer. Breast Cancer Res (2005) 2.20

Short telomeres and prognosis of hypertension in a chinese population. Hypertension (2009) 2.18

Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies. J Am Coll Cardiol (2010) 2.17

Stable gene transfer and expression in cord blood-derived CD34+ hematopoietic stem and progenitor cells by a hyperactive Sleeping Beauty transposon system. Blood (2009) 2.15

Plasma microRNAs as novel biomarkers for endometriosis and endometriosis-associated ovarian cancer. Clin Cancer Res (2013) 2.15

Inducible microRNA-155 feedback promotes type I IFN signaling in antiviral innate immunity by targeting suppressor of cytokine signaling 1. J Immunol (2010) 2.12

The E3 ubiquitin ligase Nrdp1 'preferentially' promotes TLR-mediated production of type I interferon. Nat Immunol (2009) 2.12

Genotypic and phenotypic analysis of variants resistant to hepatitis C virus nonstructural protein 5A replication complex inhibitor BMS-790052 in humans: in vitro and in vivo correlations. Hepatology (2011) 2.10

Recurrent subthreshold depression in type 2 diabetes: an important risk factor for poor health outcomes. Diabetes Care (2013) 2.08

Circulating miR-210 as a Novel Hypoxia Marker in Pancreatic Cancer. Transl Oncol (2010) 2.03

Hepatic microenvironment programs hematopoietic progenitor differentiation into regulatory dendritic cells, maintaining liver tolerance. Blood (2008) 2.02

Loss of wnt/β-catenin signaling causes cell fate shift of preosteoblasts from osteoblasts to adipocytes. J Bone Miner Res (2012) 2.01

Structure-based design of novel inhibitors of the MDM2-p53 interaction. J Med Chem (2012) 2.01

Characterizing the admixed African ancestry of African Americans. Genome Biol (2009) 2.01

Pathophysiology of contrast-induced nephropathy. Int J Cardiol (2011) 1.99

Molecular target modulation, imaging, and clinical evaluation of gastrointestinal stromal tumor patients treated with sunitinib malate after imatinib failure. Clin Cancer Res (2009) 1.99

TMEM16A induces MAPK and contributes directly to tumorigenesis and cancer progression. Cancer Res (2012) 1.98

Regulatory T cell populations in sepsis and trauma. J Leukoc Biol (2007) 1.96

A mechanism for microtubule depolymerization by KinI kinesins. Mol Cell (2002) 1.95

Estimating kinship in admixed populations. Am J Hum Genet (2012) 1.95

Notch1 signaling inhibits growth of human hepatocellular carcinoma through induction of cell cycle arrest and apoptosis. Cancer Res (2003) 1.92

Exome sequencing reveals mutations in TRPV3 as a cause of Olmsted syndrome. Am J Hum Genet (2012) 1.91

Transduction of growth or mitogenic signals into translational activation of TOP mRNAs is fully reliant on the phosphatidylinositol 3-kinase-mediated pathway but requires neither S6K1 nor rpS6 phosphorylation. Mol Cell Biol (2002) 1.90

MicroRNA-99a inhibits hepatocellular carcinoma growth and correlates with prognosis of patients with hepatocellular carcinoma. J Biol Chem (2011) 1.88

Normalization regarding non-random missing values in high-throughput mass spectrometry data. Pac Symp Biocomput (2006) 1.86

Fas signal promotes lung cancer growth by recruiting myeloid-derived suppressor cells via cancer cell-derived PGE2. J Immunol (2009) 1.85

The accumulation of deleterious mutations in rice genomes: a hypothesis on the cost of domestication. Trends Genet (2006) 1.84

SHP-2 phosphatase negatively regulates the TRIF adaptor protein-dependent type I interferon and proinflammatory cytokine production. Immunity (2006) 1.79

Programmed death-1 levels correlate with increased mortality, nosocomial infection and immune dysfunctions in septic shock patients. Crit Care (2011) 1.78

MicroRNA-148/152 impair innate response and antigen presentation of TLR-triggered dendritic cells by targeting CaMKIIα. J Immunol (2010) 1.77

Admixture mapping and the role of population structure for localizing disease genes. Adv Genet (2008) 1.76

Essential role of STAT3 in postnatal survival and growth revealed by mice lacking STAT3 serine 727 phosphorylation. Mol Cell Biol (2004) 1.76

Genome-wide association study of white blood cell count in 16,388 African Americans: the continental origins and genetic epidemiology network (COGENT). PLoS Genet (2011) 1.75

MicroRNA-9 inhibits ovarian cancer cell growth through regulation of NF-kappaB1. FEBS J (2009) 1.74

MicroRNA-466l upregulates IL-10 expression in TLR-triggered macrophages by antagonizing RNA-binding protein tristetraprolin-mediated IL-10 mRNA degradation. J Immunol (2010) 1.74

miR-221 and miR-155 regulate human dendritic cell development, apoptosis, and IL-12 production through targeting of p27kip1, KPC1, and SOCS-1. Blood (2011) 1.73

TLR4 signaling promotes immune escape of human lung cancer cells by inducing immunosuppressive cytokines and apoptosis resistance. Mol Immunol (2007) 1.72

The contribution of CD4+ CD25+ T-regulatory-cells to immune suppression in sepsis. Shock (2007) 1.71

Deficiency of cathepsin S attenuates angiotensin II-induced abdominal aortic aneurysm formation in apolipoprotein E-deficient mice. Cardiovasc Res (2012) 1.71

CD69+ CD4+ CD25- T cells, a new subset of regulatory T cells, suppress T cell proliferation through membrane-bound TGF-beta 1. J Immunol (2009) 1.70

Division of labor, plasticity, and crosstalk between dendritic cell subsets. Curr Opin Immunol (2007) 1.70

Ancestral components of admixed genomes in a Mexican cohort. PLoS Genet (2011) 1.67

Geographic distribution of disease mutations in the Ashkenazi Jewish population supports genetic drift over selection. Am J Hum Genet (2003) 1.66

The role of tumor cell-derived connective tissue growth factor (CTGF/CCN2) in pancreatic tumor growth. Cancer Res (2009) 1.64

A bacterial protein enhances the release and efficacy of liposomal cancer drugs. Science (2006) 1.64

Variation in health services utilization among ethnic populations. CMAJ (2006) 1.64

MicroRNA-494 is required for the accumulation and functions of tumor-expanded myeloid-derived suppressor cells via targeting of PTEN. J Immunol (2012) 1.63