Properties of the nuclear P1 protein, a mammalian homologue of the yeast Mcm3 replication protein.

PubWeight™: 1.71‹?› | Rank: Top 3%

🔗 View Article (PMC 312092)

Published in Nucleic Acids Res on March 11, 1992

Authors

P Thömmes1, R Fett, B Schray, R Burkhart, M Barnes, C Kennedy, N C Brown, R Knippers

Author Affiliations

1: Division of Biology, Universität Konstanz, FRG.

Articles citing this

Eukaryotic MCM proteins: beyond replication initiation. Microbiol Mol Biol Rev (2004) 4.19

A common set of conserved motifs in a vast variety of putative nucleic acid-dependent ATPases including MCM proteins involved in the initiation of eukaryotic DNA replication. Nucleic Acids Res (1993) 3.54

BM28, a human member of the MCM2-3-5 family, is displaced from chromatin during DNA replication. J Cell Biol (1995) 3.02

Apolipoprotein B mRNA-editing protein induces hepatocellular carcinoma and dysplasia in transgenic animals. Proc Natl Acad Sci U S A (1995) 2.80

Preventing re-replication of DNA in a single cell cycle: evidence for a replication licensing factor. J Cell Biol (1993) 2.44

Fission yeast cdc21+ belongs to a family of proteins involved in an early step of chromosome replication. Nucleic Acids Res (1992) 2.27

The RLF-M component of the replication licensing system forms complexes containing all six MCM/P1 polypeptides. EMBO J (1997) 2.27

Cdc45p assembles into a complex with Cdc46p/Mcm5p, is required for minichromosome maintenance, and is essential for chromosomal DNA replication. Proc Natl Acad Sci U S A (1996) 1.94

DNA polymerase alpha associated protein P1, a murine homolog of yeast MCM3, changes its intranuclear distribution during the DNA synthetic period. EMBO J (1994) 1.88

Sequential MCM/P1 subcomplex assembly is required to form a heterohexamer with replication licensing activity. J Biol Chem (2000) 1.84

Licensing of DNA replication by a multi-protein complex of MCM/P1 proteins in Xenopus eggs. EMBO J (1997) 1.83

Human and Xenopus cDNAs encoding budding yeast Cdc7-related kinases: in vitro phosphorylation of MCM subunits by a putative human homologue of Cdc7. EMBO J (1997) 1.78

Chromotin binding, nuclear localization and phosphorylation of Xenopus cdc21 are cell-cycle dependent and associated with the control of initiation of DNA replication. EMBO J (1996) 1.75

Fission yeast genes nda1+ and nda4+, mutations of which lead to S-phase block, chromatin alteration and Ca2+ suppression, are members of the CDC46/MCM2 family. Mol Biol Cell (1993) 1.61

The human homolog of Saccharomyces cerevisiae Mcm10 interacts with replication factors and dissociates from nuclease-resistant nuclear structures in G(2) phase. Nucleic Acids Res (2000) 1.49

The P1 family: a new class of nuclear mammalian proteins related to the yeast Mcm replication proteins. Nucleic Acids Res (1993) 1.46

Reversible effects of nuclear membrane permeabilization on DNA replication: evidence for a positive licensing factor. J Cell Biol (1993) 1.40

DNA-mediated transformation of bloodstream-form Trypanosoma brucei. Nucleic Acids Res (1993) 1.29

Coordinating DNA replication with cell division: current status of the licensing concept. Proc Natl Acad Sci U S A (1996) 1.27

Chromosome association of minichromosome maintenance proteins in Drosophila mitotic cycles. J Cell Biol (1997) 1.22

Chronic cardiac rejection: identification of five upregulated genes in transplanted hearts by differential mRNA display. Proc Natl Acad Sci U S A (1994) 1.13

The replication licensing system. Biol Chem (1998) 1.11

Schizosaccharomyces pombe Mcm3p, an essential nuclear protein, associates tightly with Nda4p (Mcm5p). Nucleic Acids Res (1998) 1.11

Comparative protein profiling reveals minichromosome maintenance (MCM) proteins as novel potential tumor markers for meningiomas. J Proteome Res (2010) 0.91

The mini-chromosome maintenance (Mcm) complexes interact with DNA polymerase α-primase and stimulate its ability to synthesize RNA primers. PLoS One (2013) 0.79

Characterization of Leishmania donovani MCM4: expression patterns and interaction with PCNA. PLoS One (2011) 0.76

Articles cited by this

Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (1970) 1528.65

DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci U S A (1977) 790.54

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci U S A (1979) 365.71

Transcription maps of polyoma virus-specific RNA: analysis by two-dimensional nuclease S1 gel mapping. Methods Enzymol (1980) 24.43

High-efficiency cloning of full-length cDNA. Mol Cell Biol (1982) 22.81

Animal virus DNA replication. Annu Rev Biochem (1989) 6.41

Initiation of eukaryotic DNA replication in vitro. Annu Rev Cell Biol (1989) 5.58

Binding and unwinding--how T antigen engages the SV40 origin of DNA replication. Cell (1990) 4.65

A group of interacting yeast DNA replication genes. Genes Dev (1991) 4.45

Eukaryotic DNA polymerases. Annu Rev Biochem (1991) 3.92

p53 and DNA polymerase alpha compete for binding to SV40 T antigen. Nature (1987) 3.34

T-antigen-DNA polymerase alpha complex implicated in simian virus 40 DNA replication. Mol Cell Biol (1986) 3.22

Mcm2 and Mcm3, two proteins important for ARS activity, are related in structure and function. Genes Dev (1991) 2.92

SV40 T antigen binds directly to the large subunit of purified DNA polymerase alpha. EMBO J (1990) 2.65

Effects of T antigen and replication protein A on the initiation of DNA synthesis by DNA polymerase alpha-primase. Mol Cell Biol (1991) 2.20

The phenotype of the minichromosome maintenance mutant mcm3 is characteristic of mutants defective in DNA replication. Mol Cell Biol (1990) 2.08

Isolation and characterization of expressible cDNA clones encoding the M1 and M2 subunits of mouse ribonucleotide reductase. Mol Cell Biol (1986) 1.81

Efficient production of chicken egg yolk antibodies against a conserved mammalian protein. FASEB J (1990) 1.79

DNA primase from KB cells. Characterization of a primase activity tightly associated with immunoaffinity-purified DNA polymerase-alpha. J Biol Chem (1984) 1.76

Rapid incorporation of label from ribonucleoside disphosphates into DNA by a cell-free high molecular weight fraction from animal cell nuclei. Cell (1983) 1.76

Immunoaffinity-purified DNA polymerase alpha displays novel properties. Biochemistry (1987) 1.56

A multiprotein form of DNA polymerase alpha from HeLa cells. Resolution of its associated catalytic activities. J Biol Chem (1986) 1.52

Mammalian DNA polymerase alpha holoenzymes with possible functions at the leading and lagging strand of the replication fork. Proc Natl Acad Sci U S A (1984) 1.29

Structural and enzymological characterization of immunoaffinity-purified DNA polymerase alpha.DNA primase complex from KB cells. J Biol Chem (1986) 1.25

A 21S enzyme complex from HeLa cells that functions in simian virus 40 DNA replication in vitro. Biochemistry (1990) 1.21

Brain-specific expression of MAP2 detected using a cloned cDNA probe. J Cell Biol (1986) 1.14

Synthesis of DNA polymerase alpha analyzed by immunoprecipitation from synchronously proliferating cells. Biochemistry (1986) 1.12

A mammalian DNA polymerase alpha holoenzyme functioning on defined in vivo-like templates. EMBO J (1982) 1.00

Mammalian DNA polymerase alpha: a replication competent holoenzyme form from calf thymus. Nucleic Acids Res (1987) 0.98

The core region of human glutaminyl-tRNA synthetase homologies with the Escherichia coli and yeast enzymes. Nucleic Acids Res (1988) 0.89

Reactions in vitro of the DNA polymerase-primase from Xenopus laevis eggs. A role for ATP in chain elongation. Eur J Biochem (1983) 0.88

Cloning and expression of a cDNA encoding a catalytically active fragment of calf thymus DNA polymerase alpha. Biochem Biophys Res Commun (1986) 0.83

Calcium-dependent calmodulin-binding proteins associated with mammalian DNA polymerase alpha. Biochim Biophys Acta (1988) 0.79

Articles by these authors

The [14C]deoxyglucose method for the measurement of local cerebral glucose utilization: theory, procedure, and normal values in the conscious and anesthetized albino rat. J Neurochem (1977) 11.55

Is there a basis for distinguishing two types of P2-purinoceptor? Gen Pharmacol (1985) 9.20

Process of infection with bacteriophage phiX174. XX. Attachment of the parental DNA of bacteriophage phiX174 to a fast-sedimenting cell component. J Mol Biol (1968) 6.63

DNA helicase activity of SV40 large tumor antigen. EMBO J (1986) 6.08

DNA fragments in the blood plasma of cancer patients: quantitations and evidence for their origin from apoptotic and necrotic cells. Cancer Res (2001) 5.45

Prevalence, sensitivity, and specificity of chronic cerebrospinal venous insufficiency in MS. Neurology (2011) 5.16

Structure and function of simian virus 40 large tumor antigen. Annu Rev Biochem (1992) 4.84

Venous angioplasty in patients with multiple sclerosis: results of a pilot study. Eur J Vasc Endovasc Surg (2011) 4.68

International union of pharmacology. XXIV. Current status of the nomenclature and properties of P2X receptors and their subunits. Pharmacol Rev (2001) 3.26

Structure of replicating simian virus 40 minichromosomes. The replication fork, core histone segregation and terminal structures. J Mol Biol (1986) 3.21

Complementation analysis of Klebsiella pneumoniae mutants defective in nitrogen fixation. Mol Gen Genet (1977) 3.17

6-(p-hydroxyphenylazo)-uracil: a selective inhibitor of host DNA replication in phage-infected Bacillus subtilis. Proc Natl Acad Sci U S A (1970) 3.03

Isolation and function of the gene A initiator of bacteriophage phi-chi 174, a highly specific DNA endonuclease. Proc Natl Acad Sci U S A (1974) 2.97

Inhibition of bacterial DNA replication by 6-(p-hydroxyphenylazo)-uracil: differential effect on repair and semi-conservative synthesis in Bacillus subtilis. J Mol Biol (1971) 2.91

DNA polymerase II. Nature (1970) 2.90

Inhibition of ribonucleoside diphosphate reductase by hydroxyurea. Cancer Res (1968) 2.67

A dual function for adenosine 5'-triphosphate in the regulation of vascular tone. Excitatory cotransmitter with noradrenaline from perivascular nerves and locally released inhibitory intravascular agent. Circ Res (1986) 2.60

The process of infection with Bacteriophage phi-X174. XXIX. In vivo studies on the synthesis of the single-stranded DNA of progeny phi-X174 bacteriophage. J Mol Biol (1969) 2.59

The DNA replicating capacity of isolated E. coli cell wall-membrane complexes. Nature (1970) 2.59

RNA unwinding activity of SV40 large T antigen. Cell (1989) 2.53

The Concise Guide to PHARMACOLOGY 2013/14: overview. Br J Pharmacol (2013) 2.48

Nitrogen fixation gene (nifL) involved in oxygen regulation of nitrogenase synthesis in K. pneumoniae. Nature (1981) 2.42

Measurement of local cerebral blood flow with iodo [14C] antipyrine. Am J Physiol (1978) 2.34

Polarity of mutations induced by insertion of transposons Tn5, Tn7 and Tn10 into the nif gene cluster of Klebsiella pneumoniae. Mol Gen Genet (1978) 2.32

Conditional survival among patients with carcinoma of the lung. Chest (1999) 2.30

Stages in the replication of bacteriophage phi X174 DNA in vivo. Cold Spring Harb Symp Quant Biol (1968) 2.29

Inhibition of the synthesis of deoxyribonucleic acid in bacteria by 6-(p-hydroxyphenylazo)-2,4-dihydroxypyrimidine. I. Metabolic studies in Streptococcus fecalis. J Biol Chem (1966) 2.17

Linkage map of the nitrogen fixation (nif) genes in Klebsiella pneumoniae. Mol Gen Genet (1977) 2.10

Airway dysfunction in nasal polyposis: a spectrum of asthmatic disease? Clin Exp Allergy (2011) 2.06

Camptothecin, a specific inhibitor of type I DNA topoisomerase, induces DNA breakage at replication forks. Mol Cell Biol (1988) 2.05

Interactions of human nuclear proteins P1Mcm3 and P1Cdc46. Eur J Biochem (1995) 2.03

Delay in thrombolytic treatment in acute myocardial infarction: the role of the accident and emergency department. Arch Emerg Med (1990) 2.00

Quantitative and qualitative analyses of clock drawings in Alzheimer's and Huntington's disease. Brain Cogn (1992) 1.98

Hydroxyphenylazopyrimidines: characterization of the active forms and their inhibitory action on a DNA polymerase from Bacillus subtilis. Proc Natl Acad Sci U S A (1973) 1.93

Human replication proteins hCdc21, hCdc46 and P1Mcm3 bind chromatin uniformly before S-phase and are displaced locally during DNA replication. J Cell Sci (1996) 1.92

The protein encoded by the proto-oncogene DEK changes the topology of chromatin and reduces the efficiency of DNA replication in a chromatin-specific manner. Genes Dev (2000) 1.91

Purification and characterization of human interleukin-1 beta expressed in recombinant Escherichia coli. Eur J Biochem (1986) 1.89

A large-tumor-antigen-specific monoclonal antibody inhibits DNA replication of simian virus 40 minichromosomes in an in vitro elongation system. J Virol (1985) 1.85

Design of access control methods for protecting the confidentiality of patient information in networked systems. Proc AMIA Annu Fall Symp (1997) 1.84

Ribonucleoside diphosphate reductase. Purification of the two subunits, proteins B1 and B2. Eur J Biochem (1969) 1.84

The effect of anti-intercellular adhesion molecule-1 on phorbol-ester-induced rabbit lung inflammation. J Immunol (1989) 1.76

A critical appraisal of review articles on the effectiveness of conservative treatment for neck pain. Spine (Phila Pa 1976) (2001) 1.76

Fyn and Lyn phosphorylate the Fc receptor gamma chain downstream of glycoprotein VI in murine platelets, and Lyn regulates a novel feedback pathway. Blood (2000) 1.75

The contributions of noradrenaline and ATP to the responses of the rabbit central ear artery to sympathetic nerve stimulation depend on the parameters of stimulation. Eur J Pharmacol (1986) 1.72

Comparison of benefit to sugarcane plant growth and 15N2 incorporation following inoculation of sterile plants with Acetobacter diazotrophicus wild-type and Nif- mutants strains. Mol Plant Microbe Interact (2001) 1.71

Tyrosine phosphorylation of the Fc receptor gamma-chain in collagen-stimulated platelets. J Biol Chem (1996) 1.71

P2-purinoceptors mediate both vasodilation (via the endothelium) and vasoconstriction of the isolated rat femoral artery. Eur J Pharmacol (1985) 1.71

Mapping of the gene specifying DNA polymerase III of Bacillus subtilis. Mol Gen Genet (1976) 1.70

Botulinum toxin (Dysport) treatment of hip adductor spasticity in multiple sclerosis: a prospective, randomised, double blind, placebo controlled, dose ranging study. J Neurol Neurosurg Psychiatry (2000) 1.70

Butylphenyl dGTP: a selective and potent inhibitor of mammalian DNA polymerase alpha. Nucleic Acids Res (1984) 1.70

Sequence and molecular analysis of the nifL gene of Azotobacter vinelandii. Mol Microbiol (1993) 1.69

Metabolic mapping of the primary visual system of the monkey by means of the autoradiographic [14C]deoxyglucose technique. Proc Natl Acad Sci U S A (1976) 1.68

The molybdenum--iron protein of Klebsiella pneumoniae nitrogenase. Evidence for non-identical subunits from peptide 'mapping'. Biochem J (1976) 1.68

Regulation of nitrogen metabolism in Azotobacter vinelandii: isolation of ntr and glnA genes and construction of ntr mutants. EMBO J (1986) 1.68

Ser727-dependent recruitment of MCM5 by Stat1alpha in IFN-gamma-induced transcriptional activation. EMBO J (1998) 1.68

Local cerebral blood flow during hibernation, a model of natural tolerance to "cerebral ischemia". J Cereb Blood Flow Metab (1994) 1.67

Human minichromosome maintenance proteins and human origin recognition complex 2 protein on chromatin. J Biol Chem (1998) 1.67

Inhibition of Bacillus subtilis deoxyribonucleic acid polymerase III by phenylhydrazinopyrimidines. Demonstration of a drug-induced deoxyribonucleic acid-enzyme complex. J Biol Chem (1975) 1.65

Recommendations for control and prevention of human immunodeficiency virus (HIV) infection in intravenous drug users. Ann Intern Med (1989) 1.65

Telemedicine; here to stay. Med J Aust (1997) 1.63

Isolation and molecular characterization of a highly polymorphic centromeric tandem repeat in the family Falconidae. Genomics (1988) 1.63

The severity of chronic cerebrospinal venous insufficiency in patients with multiple sclerosis is related to altered cerebrospinal fluid dynamics. Funct Neurol (2009) 1.62

Glycoprotein VI is the collagen receptor in platelets which underlies tyrosine phosphorylation of the Fc receptor gamma-chain. FEBS Lett (1997) 1.62

Major depressive and post-traumatic stress disorder comorbidity in female victims of intimate partner violence. J Affect Disord (2001) 1.61

Deoxyribonucleotide pools and deoxyribonucleic acid synthesis in cultured mouse embryo cells. J Biol Chem (1970) 1.59

Properties of the isolated gene 5 protein of bacteriophage fd. J Mol Biol (1972) 1.59

Replication protein A induces the unwinding of long double-stranded DNA regions. J Mol Biol (1996) 1.57

The human origin recognition complex protein 1 dissociates from chromatin during S phase in HeLa cells. J Biol Chem (2000) 1.57

Role of effector binding in allosteric control of ribonucleoside diphosphate reductase. J Mol Biol (1969) 1.57

Mental health service users' experiences of mental health care: an integrative literature review. J Psychiatr Ment Health Nurs (2015) 1.56

Characterization of P2-purinoceptors in the smooth muscle of the rat tail artery: a comparison between contractile and electrophysiological responses. Br J Pharmacol (1994) 1.53

The simian virus 40 large tumor antigen. Biochim Biophys Acta (1987) 1.52

Inhibition of Bacillus subtilis DNA polymerase III by arylhydrazinopyrimidines. Novel properties of 2-thiouracil derivatives. Biochim Biophys Acta (1976) 1.50

Long-term use of acid suppression started inappropriately during hospitalization. Aliment Pharmacol Ther (2005) 1.50

Neuronal release of soluble nucleotidases and their role in neurotransmitter inactivation. Nature (1997) 1.48

Activation of nif gene expression in Azotobacter by the nifA gene product of Klebsiella pneumoniae. Nature (1983) 1.48

Ribonucleoside diphosphate reductase. Formation of active and inactive complexes of proteins B1 and B2. J Mol Biol (1969) 1.47

T cell recognition of HIV synthetic peptides in a natural infection. J Immunol (1989) 1.47

The process of infection with bacteriophage phiX174. XXVI. Transfer of the parental DNA of bacteriophage phiX174 into progeny bacteriophage particles. J Mol Biol (1969) 1.47

ATP produces vasodilation via P1 purinoceptors and vasoconstriction via P2 purinoceptors in the isolated rabbit central ear artery. Blood Vessels (1985) 1.46

The complete DNA sequence of the Ectocarpus siliculosus Virus EsV-1 genome. Virology (2001) 1.46

The P1 family: a new class of nuclear mammalian proteins related to the yeast Mcm replication proteins. Nucleic Acids Res (1993) 1.46

Small bacteriophages. Adv Virus Res (1966) 1.45

Cloning and mutagenesis of genes encoding the cytochrome bd terminal oxidase complex in Azotobacter vinelandii: mutants deficient in the cytochrome d complex are unable to fix nitrogen in air. J Bacteriol (1990) 1.45

Asymmetric repair of bacteriophage T7 heteroduplex DNA. Mol Gen Genet (1981) 1.44

Evidence for two types of P2-purinoceptor in longitudinal muscle of the rabbit portal vein. Eur J Pharmacol (1985) 1.43

Stability of the replicative Mcm3 protein in proliferating and differentiating human cells. Exp Cell Res (1998) 1.43

Pyelonephritis, rash, and progressive respiratory failure in a pregnant woman. Clin Infect Dis (1992) 1.42

Mapping of functional neural pathways by autoradiographic survey of local metabolic rate with (14C)deoxyglucose. Science (1975) 1.42

Inhibition of bacterial DNA replication by 6-(p-hydroxy-phenylazo)-uracil. Nat New Biol (1972) 1.42

Inhibition of a discrete bacterial DNA polymerase by 6-(p-hydroxyphenylazo)-uracil and 6-(p-hydroxyphenylazo-)-isocytosine. Nat New Biol (1972) 1.41

Morphology and physical properties of Staphylococcus bacteriophage P11-M15. J Virol (1972) 1.41

A human homologue of the yeast replication protein Cdc21. Interactions with other Mcm proteins. Eur J Biochem (1995) 1.40

A coat protein from bacteriophage fd. I. Hydrodynamic measurements and biological characterization. J Mol Biol (1966) 1.39

Antibody to B. subtilis DNA polymerase III: use in enzyme purification and examination of homology among replication-specific DNA polymerases. Nucleic Acids Res (1979) 1.39

"Being dealt with as a whole person." Care seeking and adherence: the benefits of culturally competent care. Soc Sci Med (2001) 1.39

Mammographically negative breast cancer at the Strathfield Breast Centre. Aust N Z J Surg (1996) 1.38

Human cathepsin V functional expression, tissue distribution, electrostatic surface potential, enzymatic characterization, and chromosomal localization. Biochemistry (1999) 1.38