Published in Mol Ther on November 01, 2004
Integration site preference of xenotropic murine leukemia virus-related virus, a new human retrovirus associated with prostate cancer. J Virol (2008) 2.83
Multilineage hematopoietic reconstitution without clonal selection in ADA-SCID patients treated with stem cell gene therapy. J Clin Invest (2007) 2.63
Retroviral vector integration deregulates gene expression but has no consequence on the biology and function of transplanted T cells. Proc Natl Acad Sci U S A (2006) 2.06
Preferential delivery of the Sleeping Beauty transposon system to livers of mice by hydrodynamic injection. Nat Protoc (2007) 1.73
Transcription factor binding sites are genetic determinants of retroviral integration in the human genome. PLoS One (2009) 1.46
Cytokine-independent growth and clonal expansion of a primary human CD8+ T-cell clone following retroviral transduction with the IL-15 gene. Blood (2007) 1.32
Delivering the goods: viral and non-viral gene therapy systems and the inherent limits on cargo DNA and internal sequences. Genetica (2010) 1.13
Gene therapy vectors: the prospects and potentials of the cut-and-paste transposons. Genetica (2009) 1.10
Predicting preferential DNA vector insertion sites: implications for functional genomics and gene therapy. Genome Biol (2007) 1.08
Efficacy and safety of Sleeping Beauty transposon-mediated gene transfer in preclinical animal studies. Curr Gene Ther (2011) 1.08
Chromosomal integration of adenoviral vector DNA in vivo. J Virol (2010) 1.07
Unaltered repopulation properties of mouse hematopoietic stem cells transduced with lentiviral vectors. Blood (2008) 1.02
Concise review: lessons learned from clinical trials of gene therapy in monogenic immunodeficiency diseases. Stem Cells Transl Med (2014) 0.97
Gene expression in lung and liver after intravenous infusion of polyethylenimine complexes of Sleeping Beauty transposons. Hum Gene Ther (2010) 0.92
Live and let die: in vivo selection of gene-modified hematopoietic stem cells via MGMT-mediated chemoprotection. DNA Repair (Amst) (2007) 0.92
LDLR-Gene therapy for familial hypercholesterolaemia: problems, progress, and perspectives. Int Arch Med (2010) 0.91
Retroviral insertional mutagenesis can contribute to immortalization of mature T lymphocytes. Mol Med (2011) 0.88
Viral determinants of integration site preferences of simian immunodeficiency virus-based vectors. J Virol (2006) 0.82
Mature T-cell lymphomagenesis induced by retroviral insertional activation of Janus kinase 1. Mol Ther (2013) 0.82
Erythroid-specific expression of β-globin from Sleeping Beauty-transduced human hematopoietic progenitor cells. PLoS One (2011) 0.81
Multiple displacement amplification enables large-scale clonal analysis following retroviral gene therapy. J Virol (2007) 0.79
β-Globin sleeping beauty transposon reduces red blood cell sickling in a patient-derived CD34(+)-based in vitro model. PLoS One (2013) 0.78
A comparison of foamy and lentiviral vector genotoxicity in SCID-repopulating cells shows foamy vectors are less prone to clonal dominance. Mol Ther Methods Clin Dev (2016) 0.77
Gene therapy model of X-linked severe combined immunodeficiency using a modified foamy virus vector. PLoS One (2013) 0.75
Analysis of PBase Binding Profile Indicates an Insertion Target Selection Mechanism Dependent on TTAA, But Not Transcriptional Activity. Int J Biol Sci (2016) 0.75
Comparative analysis of transposed element insertion within human and mouse genomes reveals Alu's unique role in shaping the human transcriptome. Genome Biol (2007) 2.35
Development and optimization of a real-time quantitative PCR-based method for the titration of AAV-2 vector stocks. Mol Ther (2002) 1.75
Retroviral vector integration occurs in preferred genomic targets of human bone marrow-repopulating cells. Blood (2002) 1.65
Functions, structure, and read-through alternative splicing of feline APOBEC3 genes. Genome Biol (2008) 1.63
High-throughput SNP-based authentication of human cell lines. Int J Cancer (2012) 1.46
Characterization of human mesothelioma cell lines as tumor models for suicide gene therapy. Onkologie (2008) 1.44
In vivo micro-CT imaging of untreated and irradiated orthotopic glioblastoma xenografts in mice: capabilities, limitations and a comparison with bioluminescence imaging. J Neurooncol (2015) 1.43
Off-target effects of siRNA specific for GFP. BMC Mol Biol (2008) 1.41
miR-137 inhibits the invasion of melanoma cells through downregulation of multiple oncogenic target genes. J Invest Dermatol (2012) 1.23
Characteristics of transposable element exonization within human and mouse. PLoS One (2010) 1.09
SplicingCompass: differential splicing detection using RNA-seq data. Bioinformatics (2013) 1.07
SERpredict: detection of tissue- or tumor-specific isoforms generated through exonization of transposable elements. BMC Genet (2007) 1.05
Isolation of multiple TT virus genotypes from spleen biopsy tissue from a Hodgkin's disease patient: genome reorganization and diversity in the hypervariable region. J Virol (2004) 1.04
Estimation of intracranial failure risk following hippocampal-sparing whole brain radiotherapy. Radiother Oncol (2013) 0.99
Overnight transduction with foamyviral vectors restores the long-term repopulating activity of Fancc-/- stem cells. Blood (2008) 0.99
New miRNAs cloned from neuroblastoma. BMC Genomics (2008) 0.98
Effect of CD34 cell dose on hematopoietic reconstitution and outcome in 508 patients with multiple myeloma undergoing autologous peripheral blood stem cell transplantation. Eur J Haematol (2006) 0.94
Proteomic analysis of tardigrades: towards a better understanding of molecular mechanisms by anhydrobiotic organisms. PLoS One (2010) 0.94
A Lentiviral CXCR4 overexpression and knockdown model in colorectal cancer cell lines reveals plerixafor-dependent suppression of SDF-1α-induced migration and invasion. Onkologie (2011) 0.94
SNAI2 as a novel radioprotector of normal tissue by gene transfer using a lentiviral bicistronic SIN vector. Radiat Res (2010) 0.94
The CXCR4 antagonist AMD3100 releases a subset of G-CSF-primed peripheral blood progenitor cells with specific gene expression characteristics. Exp Hematol (2006) 0.92
Differences in functional activity and antigen expression of granulocytes primed in vivo with filgrastim, lenograstim, or pegfilgrastim. Transfusion (2007) 0.90
Lentiviral vector integration sites in human NOD/SCID repopulating cells. J Gene Med (2006) 0.90
Establishment and characterization of a highly tumourigenic and cancer stem cell enriched pancreatic cancer cell line as a well defined model system. PLoS One (2012) 0.89
Clonal inventory screens uncover monoclonality following serial transplantation of MGMT P140K-transduced stem cells and dose-intense chemotherapy. Hum Gene Ther (2011) 0.89
Overexpression of MDR1 using a retroviral vector differentially regulates genes involved in detoxification and apoptosis and confers radioprotection. Radiat Res (2006) 0.88
In-depth mass spectrometric mapping of the human vitreous proteome. Proteome Sci (2013) 0.86
Allogeneic haematopoietic cell transplantation for chronic myelogenous leukaemia in the era of imatinib: a retrospective multicentre study. Eur J Haematol (2006) 0.86
CXCR4 Expression and Treatment with SDF-1α or Plerixafor Modulate Proliferation and Chemosensitivity of Colon Cancer Cells. Transl Oncol (2013) 0.85
Good manufacturing practice-grade production of unrestricted somatic stem cell from fresh cord blood. Cytotherapy (2010) 0.85
Automatic detection of exonic splicing enhancers (ESEs) using SVMs. BMC Bioinformatics (2008) 0.84
Long-term episomal transgene expression from mitotically stable integration-deficient lentiviral vectors. Hum Gene Ther (2014) 0.84
Genome-wide prediction of splice-modifying SNPs in human genes using a new analysis pipeline called AASsites. BMC Bioinformatics (2011) 0.84
Pseudotyped recombinant adeno-associated viral vectors mediate efficient gene transfer into primary human CD34(+) peripheral blood progenitor cells. Cytotherapy (2010) 0.84
ATF2 knockdown reinforces oxidative stress-induced apoptosis in TE7 cancer cells. J Cell Mol Med (2013) 0.84
Retroviral integration sites correlate with expressed genes in hematopoietic stem cells. Stem Cells (2005) 0.84
Generation of efficient human blood progenitor-targeted recombinant adeno-associated viral vectors (AAV) by applying an AAV random peptide library on primary human hematopoietic progenitor cells. Exp Hematol (2008) 0.83
Clonal analysis of individual marrow-repopulating cells after experimental peripheral blood progenitor cell transplantation. Stem Cells (2004) 0.83
Multidrug resistance 1 gene transfer can confer chemoprotection to human peripheral blood progenitor cells engrafted in immunodeficient mice. Hum Gene Ther (2002) 0.83
The disparate twins: a comparative study of CXCR4 and CXCR7 in SDF-1α-induced gene expression, invasion and chemosensitivity of colon cancer. Clin Cancer Res (2013) 0.82
MDR1 gene transfer using a lentiviral SIN vector confers radioprotection to human CD34+ hematopoietic progenitor cells. Radiat Res (2008) 0.82
Viral determinants of integration site preferences of simian immunodeficiency virus-based vectors. J Virol (2006) 0.82
The transcriptome of the colonial marine hydroid Hydractinia echinata. FEBS J (2009) 0.81
Relevance and clinical implications of tumor cell mobilization in the autologous transplant setting. Biol Blood Marrow Transplant (2010) 0.81
Level of CD 20-expression and efficacy of rituximab treatment in patients with resistant or relapsing B-cell prolymphocytic leukemia and B-cell chronic lymphocytic leukemia. Leuk Lymphoma (2002) 0.81
Unrestricted somatic stem cells: interaction with CD34+ cells in vitro and in vivo, expression of homing genes and exclusion of tumorigenic potential. Cytotherapy (2010) 0.81
Study design: two long-term observational studies of the biosimilar filgrastim Nivestim™ (Hospira filgrastim) in the treatment and prevention of chemotherapy-induced neutropenia. BMC Cancer (2013) 0.81
Application of a haematopoetic progenitor cell-targeted adeno-associated viral (AAV) vector established by selection of an AAV random peptide library on a leukaemia cell line. Genet Vaccines Ther (2008) 0.80
Identification of the feline foamy virus Bet domain essential for APOBEC3 counteraction. Retrovirology (2013) 0.80
No evidence of clonal dominance in primates up to 4 years following transplantation of multidrug resistance 1 retrovirally transduced long-term repopulating cells. Stem Cells (2007) 0.80
Kinetics of peripheral blood stem cell mobilization following G-CSF-supported chemotherapy. Stem Cells (2003) 0.80
CD166/ALCAM mediates proinflammatory effects of S100B in delayed type hypersensitivity. J Immunol (2013) 0.80
Overexpression of caveolin-1 in lymphoblastoid TK6 cells enhances proliferation after irradiation with clinically relevant doses. Strahlenther Onkol (2010) 0.80
Suicide gene therapy of sarcoma cell lines using recombinant adeno-associated virus 2 vectors. Cancer Gene Ther (2004) 0.80
Recombinant adeno-associated virus 2-mediated transfer of the human superoxide-dismutase gene does not confer radioresistance on HeLa cervical carcinoma cells. Radiother Oncol (2004) 0.79
Interdependent regulation of insulin receptor kinase activity by ADP and hydrogen peroxide. J Biol Chem (2004) 0.79
Combination treatment of imatinib-sensitive and -resistant BCR-ABL-positive CML cells with imatinib and farnesyltransferase inhibitors. Anticancer Res (2006) 0.79
Comparative proteome analysis of Milnesium tardigradum in early embryonic state versus adults in active and anhydrobiotic state. PLoS One (2012) 0.79
Normal-tissue radioprotection by overexpression of the copper-zinc and manganese superoxide dismutase genes. Strahlenther Onkol (2009) 0.79
Overexpression of manganese superoxide dismutase does not increase clonogenic cell survival despite effect on apoptosis in irradiated lymphoblastoid cells. Radiat Res (2011) 0.78
Individual quality assessment of autografting by probability estimation for clinical endpoints: a prospective validation study from the European group for blood and marrow transplantation. Biol Blood Marrow Transplant (2013) 0.78
Susceptibility of mesothelioma cell lines to adeno-associated virus 2 vector-based suicide gene therapy. Lung Cancer (2004) 0.78
Quantitative real-time polymerase chain reaction shows that treatment with interferon reduces the initially upregulated PRV-1 expression in polycythemia vera patients. Haematologica (2003) 0.77
Long-term follow-up of patients with non-Hodgkin lymphoma following myeloablative therapy and autologous transplantation of CD34+-selected peripheral blood progenitor cells. Stem Cells (2007) 0.77
Induced and repressed genes after irradiation sensitizing by pentoxyphylline. Int J Cancer (2007) 0.77
Synergistic activity of nilotinib and established chemotherapeutic drugs in imatinib-sensitive and -resistant BCR-ABL-positive cells. Cancer Chemother Pharmacol (2009) 0.76
Development of leukocytoclastic vasculitis in a patient with multiple myeloma during treatment with thalidomide. Ann Hematol (2003) 0.76
Nuclear ARVCF protein binds splicing factors and contributes to the regulation of alternative splicing. J Biol Chem (2014) 0.76
CAFTAN: a tool for fast mapping, and quality assessment of cDNAs. BMC Bioinformatics (2006) 0.75
Spatial localization of genes determined by intranuclear DNA fragmentation with the fusion proteins lamin KRED and histone KRED und visible light. Int J Med Sci (2013) 0.75
Secondary follicular lymphoma of the bone, transformed into large cell lymphoma, in a patient with chronic lymphocytic leukaemia: an uncommon manifestation of Richter's syndrome. Eur J Haematol (2004) 0.75
Cross-resistance of imatinib mesylate and 17-AAG in imatinib-resistant cells that overexpress BCR-ABL. Br J Haematol (2003) 0.75
Combined stereotactic biopsy and stepping-source interstitial irradiation of unresectable glioblastoma multiforme. J Neurosurg Sci (2016) 0.75
²³Na-MRI of recurrent glioblastoma multiforme after intraoperative radiotherapy: technical note. Neuroradiology (2014) 0.75
In vitro testing of drug combinations employing nilotinib and alkylating agents with regard to pretransplant conditioning treatment of advanced-phase chronic myeloid leukemia. Cancer Chemother Pharmacol (2014) 0.75