Published in Eur J Cell Biol on July 01, 2004
TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-beta. Nat Immunol (2008) 7.87
Molecular mechanism and physiological functions of clathrin-mediated endocytosis. Nat Rev Mol Cell Biol (2011) 6.32
Endocytosis of the anthrax toxin is mediated by clathrin, actin and unconventional adaptors. PLoS Pathog (2010) 1.35
Anthrax toxin triggers the activation of src-like kinases to mediate its own uptake. Proc Natl Acad Sci U S A (2010) 1.03
Membrane fission by dynamin: what we know and what we need to know. EMBO J (2016) 0.91
Efficient neutralization of antibody-resistant forms of anthrax toxin by a soluble receptor decoy inhibitor. Antimicrob Agents Chemother (2008) 0.91
Membrane insertion by anthrax protective antigen in cultured cells. Mol Cell Biol (2005) 0.87
Evidence against a human cell-specific role for LRP6 in anthrax toxin entry. PLoS One (2008) 0.87
Caveolin-1 and dynamin-2 are essential for removal of the complement C5b-9 complex via endocytosis. J Biol Chem (2012) 0.84
NAD+-Glycohydrolase Promotes Intracellular Survival of Group A Streptococcus. PLoS Pathog (2016) 0.79
The Ins and Outs of Anthrax Toxin. Toxins (Basel) (2016) 0.77
Polylysine-mediated translocation of the diphtheria toxin catalytic domain through the anthrax protective antigen pore. Biochemistry (2014) 0.77
Dynasore, a cell-permeable inhibitor of dynamin. Dev Cell (2006) 13.15
Endocytosis by random initiation and stabilization of clathrin-coated pits. Cell (2004) 6.75
Anthrax toxin: receptor binding, internalization, pore formation, and translocation. Annu Rev Biochem (2007) 5.38
Molecular model for a complete clathrin lattice from electron cryomicroscopy. Nature (2004) 4.48
A phenylalanine clamp catalyzes protein translocation through the anthrax toxin pore. Science (2005) 4.10
Phosphatidylinositol 4 phosphate regulates targeting of clathrin adaptor AP-1 complexes to the Golgi. Cell (2003) 3.75
Structure of heptameric protective antigen bound to an anthrax toxin receptor: a role for receptor in pH-dependent pore formation. Proc Natl Acad Sci U S A (2004) 3.10
Endosomal recycling controls plasma membrane area during mitosis. Proc Natl Acad Sci U S A (2007) 2.86
Stoichiometry of anthrax toxin complexes. Biochemistry (2002) 2.86
Distinct dynamics of endocytic clathrin-coated pits and coated plaques. PLoS Biol (2009) 2.83
Protein translocation through the anthrax toxin transmembrane pore is driven by a proton gradient. J Mol Biol (2005) 2.69
The mode of bone morphogenetic protein (BMP) receptor oligomerization determines different BMP-2 signaling pathways. J Biol Chem (2001) 2.59
PA63 channel of anthrax toxin: an extended beta-barrel. Biochemistry (2002) 2.57
Binding stoichiometry and kinetics of the interaction of a human anthrax toxin receptor, CMG2, with protective antigen. J Biol Chem (2004) 2.57
Invasive and adherent bacterial pathogens co-Opt host clathrin for infection. Cell Host Microbe (2007) 2.53
Mapping the lethal factor and edema factor binding sites on oligomeric anthrax protective antigen. Proc Natl Acad Sci U S A (2002) 2.51
Lymphocyte crawling and transendothelial migration require chemokine triggering of high-affinity LFA-1 integrin. Immunity (2009) 2.50
Actin dynamics counteract membrane tension during clathrin-mediated endocytosis. Nat Cell Biol (2011) 2.48
Acid-induced unfolding of the amino-terminal domains of the lethal and edema factors of anthrax toxin. J Mol Biol (2004) 2.35
The lethal and edema factors of anthrax toxin bind only to oligomeric forms of the protective antigen. Proc Natl Acad Sci U S A (2002) 2.31
Crystal structure of the clathrin adaptor protein 1 core. Proc Natl Acad Sci U S A (2004) 2.28
Evidence that translocation of anthrax toxin's lethal factor is initiated by entry of its N terminus into the protective antigen channel. Proc Natl Acad Sci U S A (2004) 2.23
An open letter to Elias Zerhouni. Science (2005) 2.19
Cryo-electron tomography of clathrin-coated vesicles: structural implications for coat assembly. J Mol Biol (2006) 2.17
Receptor-specific requirements for anthrax toxin delivery into cells. Proc Natl Acad Sci U S A (2005) 2.15
A burst of auxilin recruitment determines the onset of clathrin-coated vesicle uncoating. Proc Natl Acad Sci U S A (2006) 2.12
Perforin triggers a plasma membrane-repair response that facilitates CTL induction of apoptosis. Immunity (2005) 2.11
Role of lipids and actin in the formation of clathrin-coated pits. Exp Cell Res (2006) 2.01
Association of Dishevelled with the clathrin AP-2 adaptor is required for Frizzled endocytosis and planar cell polarity signaling. Dev Cell (2007) 1.99
GroEL as a molecular scaffold for structural analysis of the anthrax toxin pore. Nat Struct Mol Biol (2008) 1.91
The structural basis for substrate and inhibitor selectivity of the anthrax lethal factor. Nat Struct Mol Biol (2003) 1.91
Crystal structure of the von Willebrand factor A domain of human capillary morphogenesis protein 2: an anthrax toxin receptor. Proc Natl Acad Sci U S A (2004) 1.91
Protein translocation through anthrax toxin channels formed in planar lipid bilayers. Biophys J (2004) 1.87
Differential evanescence nanometry: live-cell fluorescence measurements with 10-nm axial resolution on the plasma membrane. Biophys J (2007) 1.85
Secramine inhibits Cdc42-dependent functions in cells and Cdc42 activation in vitro. Nat Chem Biol (2005) 1.84
The small chemical vacuolin-1 inhibits Ca(2+)-dependent lysosomal exocytosis but not cell resealing. EMBO Rep (2004) 1.82
Structure of an auxilin-bound clathrin coat and its implications for the mechanism of uncoating. Nature (2004) 1.81
Discovery of chemical inhibitors of the selective transfer of lipids mediated by the HDL receptor SR-BI. Proc Natl Acad Sci U S A (2002) 1.67
Macropinocytosis: regulated coordination of endocytic and exocytic membrane traffic events. J Cell Sci (2006) 1.64
PI4P promotes the recruitment of the GGA adaptor proteins to the trans-Golgi network and regulates their recognition of the ubiquitin sorting signal. Mol Biol Cell (2007) 1.63
Mapping the anthrax protective antigen binding site on the lethal and edema factors. J Biol Chem (2001) 1.62
Mapping dominant-negative mutations of anthrax protective antigen by scanning mutagenesis. Proc Natl Acad Sci U S A (2003) 1.59
A model of anthrax toxin lethal factor bound to protective antigen. Proc Natl Acad Sci U S A (2005) 1.58
Perforin pores in the endosomal membrane trigger the release of endocytosed granzyme B into the cytosol of target cells. Nat Immunol (2011) 1.57
The delta region of outer-capsid protein micro 1 undergoes conformational change and release from reovirus particles during cell entry. J Virol (2003) 1.56
Exo1: a new chemical inhibitor of the exocytic pathway. Proc Natl Acad Sci U S A (2003) 1.55
A soluble receptor decoy protects rats against anthrax lethal toxin challenge. J Infect Dis (2005) 1.54
A dually active anthrax vaccine that confers protection against both bacilli and toxins. Proc Natl Acad Sci U S A (2003) 1.54
Endoplasmic reticulum (ER) mannosidase I is compartmentalized and required for N-glycan trimming to Man5-6GlcNAc2 in glycoprotein ER-associated degradation. Mol Biol Cell (2007) 1.49
L1 endocytosis is controlled by a phosphorylation-dephosphorylation cycle stimulated by outside-in signaling by L1. J Cell Biol (2002) 1.47
Targeting of AMSH to endosomes is required for epidermal growth factor receptor degradation. J Biol Chem (2007) 1.42
Formation of the postmitotic nuclear envelope from extended ER cisternae precedes nuclear pore assembly. J Cell Biol (2011) 1.41
Effect of 2-fluorohistidine labeling of the anthrax protective antigen on stability, pore formation, and translocation. Biochemistry (2007) 1.40
Roles of AP-2 in clathrin-mediated endocytosis. PLoS One (2010) 1.40
The length of vesicular stomatitis virus particles dictates a need for actin assembly during clathrin-dependent endocytosis. PLoS Pathog (2010) 1.40
Antiinflammatory cAMP signaling and cell migration genes co-opted by the anthrax bacillus. Proc Natl Acad Sci U S A (2008) 1.39
A monoclonal antibody to Bacillus anthracis protective antigen defines a neutralizing epitope in domain 1. Infect Immun (2006) 1.38
An ACAP1-containing clathrin coat complex for endocytic recycling. J Cell Biol (2007) 1.38
Small molecule-mediated TGF-β type II receptor degradation promotes cardiomyogenesis in embryonic stem cells. Cell Stem Cell (2012) 1.34
Anthrax toxin receptor 2-dependent lethal toxin killing in vivo. PLoS Pathog (2006) 1.34
Cholera toxin toxicity does not require functional Arf6- and dynamin-dependent endocytic pathways. Mol Biol Cell (2004) 1.32
2001: a year of major advances in anthrax toxin research. Trends Microbiol (2002) 1.32
Structural determinants for the binding of anthrax lethal factor to oligomeric protective antigen. J Biol Chem (2005) 1.30
Transforming growth factor-beta receptors interact with AP2 by direct binding to beta2 subunit. Mol Biol Cell (2002) 1.29
Retrograde transport of cholera toxin from the plasma membrane to the endoplasmic reticulum requires the trans-Golgi network but not the Golgi apparatus in Exo2-treated cells. EMBO Rep (2004) 1.28
Mammalian cells change volume during mitosis. PLoS One (2008) 1.28
The mu2 subunit of the clathrin adaptor AP-2 binds to FDNPVY and YppØ sorting signals at distinct sites. Traffic (2002) 1.27
The transcription factor NFAT3 mediates neuronal survival. J Biol Chem (2004) 1.27
Single-molecule analysis of a molecular disassemblase reveals the mechanism of Hsc70-driven clathrin uncoating. Nat Struct Mol Biol (2011) 1.26
Insertion of anthrax protective antigen into liposomal membranes: effects of a receptor. J Biol Chem (2006) 1.26
Concomitant expression of the chemokines RANTES and MCP-1 in human breast cancer: a basis for tumor-promoting interactions. Cytokine (2008) 1.25
Phenylalanine-427 of anthrax protective antigen functions in both pore formation and protein translocation. Proc Natl Acad Sci U S A (2008) 1.25
Combining anthrax vaccine and therapy: a dominant-negative inhibitor of anthrax toxin is also a potent and safe immunogen for vaccines. Infect Immun (2005) 1.22
Evidence for a proton-protein symport mechanism in the anthrax toxin channel. J Gen Physiol (2009) 1.20
Conformational changes in BID, a pro-apoptotic BCL-2 family member, upon membrane binding. A site-directed spin labeling study. J Biol Chem (2004) 1.20
Anthrax toxin complexes: heptameric protective antigen can bind lethal factor and edema factor simultaneously. Biochem Biophys Res Commun (2004) 1.19
A loop network within the anthrax toxin pore positions the phenylalanine clamp in an active conformation. Proc Natl Acad Sci U S A (2006) 1.18
Initiation of Smad-dependent and Smad-independent signaling via distinct BMP-receptor complexes. J Bone Joint Surg Am (2003) 1.18
Clustering of raft-associated proteins in the external membrane leaflet modulates internal leaflet H-ras diffusion and signaling. Mol Cell Biol (2006) 1.18
Reversible refolding of the diphtheria toxin T-domain on lipid membranes. Biochemistry (2004) 1.17
Anthrax toxin receptor 2 determinants that dictate the pH threshold of toxin pore formation. PLoS One (2007) 1.16
Structure of clathrin coat with bound Hsc70 and auxilin: mechanism of Hsc70-facilitated disassembly. EMBO J (2009) 1.16
Cross-inhibition of SR-BI- and ABCA1-mediated cholesterol transport by the small molecules BLT-4 and glyburide. J Lipid Res (2004) 1.15
TMPRSS2/ERG promotes epithelial to mesenchymal transition through the ZEB1/ZEB2 axis in a prostate cancer model. PLoS One (2011) 1.15
A semisynthesis platform for investigating structure-function relationships in the N-terminal domain of the anthrax Lethal Factor. ACS Chem Biol (2010) 1.12
Dab2 regulates clathrin assembly and cell spreading. Biochem J (2009) 1.11
Endocytosis and recycling of immune complexes by follicular dendritic cells enhances B cell antigen binding and activation. Immunity (2013) 1.11
A Legionella effector acquired from protozoa is involved in sphingolipids metabolism and is targeted to the host cell mitochondria. Cell Microbiol (2009) 1.11
Protein complexes containing CYFIP/Sra/PIR121 coordinate Arf1 and Rac1 signalling during clathrin-AP-1-coated carrier biogenesis at the TGN. Nat Cell Biol (2010) 1.11
p12 tethers the murine leukemia virus pre-integration complex to mitotic chromosomes. PLoS Pathog (2012) 1.10
T cells induce extended class II MHC compartments in dendritic cells in a Toll-like receptor-dependent manner. J Immunol (2003) 1.09
Rapid homogenous detection of the Ibaraki virus NS3 cDNA at picomolar concentrations by magnetic modulation. Biosens Bioelectron (2009) 1.09
Whole-cell voltage clamp measurements of anthrax toxin pore current. J Biol Chem (2005) 1.09
Anthrax lethal toxin induces cell death-independent permeability in zebrafish vasculature. Proc Natl Acad Sci U S A (2008) 1.08
Pathway- and expression level-dependent effects of oncogenic N-Ras: p27(Kip1) mislocalization by the Ral-GEF pathway and Erk-mediated interference with Smad signaling. Mol Cell Biol (2005) 1.08
Targeting HER2-positive cancer cells with receptor-redirected anthrax protective antigen. Mol Oncol (2012) 1.07