Double-stranded RNAs from the helminth parasite Schistosoma activate TLR3 in dendritic cells.

PubWeight™: 1.44‹?› | Rank: Top 5%

🔗 View Article (PMID 15519998)

Published in J Biol Chem on November 01, 2004

Authors

Ezra Aksoy1, Claudia S Zouain, François Vanhoutte, Josette Fontaine, Norman Pavelka, Nathalie Thieblemont, Fabienne Willems, Paola Ricciardi-Castagnoli, Michel Goldman, Monique Capron, Bernard Ryffel, François Trottein

Author Affiliations

1: INSERM U547, Institut Pasteur de Lille, Lille 59019, France.

Articles citing this

A type I interferon autocrine-paracrine loop is involved in Toll-like receptor-induced interleukin-12p70 secretion by dendritic cells. J Exp Med (2005) 3.59

The major component in schistosome eggs responsible for conditioning dendritic cells for Th2 polarization is a T2 ribonuclease (omega-1). J Exp Med (2009) 2.34

Innate immune responses to lung-stage helminth infection induce alternatively activated alveolar macrophages. Infect Immun (2006) 1.76

Helminth-derived immunomodulators: can understanding the worm produce the pill? Nat Rev Immunol (2010) 1.66

Review series on helminths, immune modulation and the hygiene hypothesis: mechanisms underlying helminth modulation of dendritic cell function. Immunology (2009) 1.48

Toll-like receptors and leishmaniasis. Infect Immun (2007) 1.27

Expression and distribution of Toll-like receptors in the brain during murine neurocysticercosis. J Neuroimmunol (2006) 1.24

Manifold mechanisms of Toll-like receptor-ligand recognition. J Clin Immunol (2005) 1.22

Schistosome larvae stimulate macrophage cytokine production through TLR4-dependent and -independent pathways. Int Immunol (2005) 1.19

Toll-like receptors and immune regulation: their direct and indirect modulation on regulatory CD4+ CD25+ T cells. Immunology (2007) 1.16

Galectin-3 modulates immune and inflammatory responses during helminthic infection: impact of galectin-3 deficiency on the functions of dendritic cells. Infect Immun (2007) 1.12

Invariant and noninvariant natural killer T cells exert opposite regulatory functions on the immune response during murine schistosomiasis. Infect Immun (2007) 1.12

Activation and regulation of toll-like receptors (TLRs) by helminth parasites. Immunol Res (2009) 1.07

Schistosoma mansoni egg antigen-mediated modulation of Toll-like receptor (TLR)-induced activation occurs independently of TLR2, TLR4, and MyD88. Infect Immun (2008) 1.05

The danger signal S100B integrates pathogen- and danger-sensing pathways to restrain inflammation. PLoS Pathog (2011) 1.05

Human schistosomiasis is associated with endotoxemia and Toll-like receptor 2- and 4-bearing B cells. Am J Trop Med Hyg (2011) 1.02

Pattern recognition via the toll-like receptor system in the human female genital tract. Mediators Inflamm (2010) 1.01

Helminth infections and intestinal inflammation. World J Gastroenterol (2008) 1.00

Ascaris suum-derived products suppress mucosal allergic inflammation in an interleukin-10-independent manner via interference with dendritic cell function. Infect Immun (2006) 0.99

Synergy between viral and bacterial toll-like receptors leads to amplification of inflammatory responses and preterm labor in the mouse. Biol Reprod (2010) 0.98

Modulation of specific and allergy-related immune responses by helminths. J Biomed Biotechnol (2011) 0.98

Selective induction of the Notch ligand Jagged-1 in macrophages by soluble egg antigen from Schistosoma mansoni involves ERK signalling. Immunology (2008) 0.97

Regulation of apoptosis and innate immune stimuli in inflammation-induced preterm labor. J Immunol (2013) 0.93

Innate recognition of non-self nucleic acids. Genome Biol (2008) 0.92

Schistosome ABC multidrug transporters: From pharmacology to physiology. Int J Parasitol Drugs Drug Resist (2014) 0.89

Complementary function of gamma delta T-lymphocytes and dendritic cells in the response to isopentenyl-pyrophosphate and lipopolysaccharide antigens. J Clin Immunol (2005) 0.88

Enhanced pro-inflammatory cytokine responses following Toll-like-receptor ligation in Schistosoma haematobium-infected schoolchildren from rural Gabon. PLoS One (2011) 0.87

Distinct Toll-like receptor signals regulate cerebral parasite load and interferon α/β and tumor necrosis factor α-dependent T-cell infiltration in the brains of Trypanosoma brucei-infected mice. J Infect Dis (2011) 0.87

Priming dendritic cells for th2 polarization: lessons learned from helminths and implications for metabolic disorders. Front Immunol (2014) 0.86

TLR3 modulates immunopathology during a Schistosoma mansoni egg-driven Th2 response in the lung. Eur J Immunol (2008) 0.86

Uncoupling of induced protein processing from maturation in dendritic cells exposed to a highly antigenic preparation from a helminth parasite. J Immunol (2008) 0.86

Protease-activated receptor 2 is involved in Th2 responses against Trichinella spiralis infection. Korean J Parasitol (2011) 0.86

Age-related patterns in human myeloid dendritic cell populations in people exposed to Schistosoma haematobium infection. PLoS Negl Trop Dis (2012) 0.86

MyD88 signaling inhibits protective immunity to the gastrointestinal helminth parasite Heligmosomoides polygyrus. J Immunol (2014) 0.84

Immunomodulation in Plasmodium falciparum malaria: experiments in nature and their conflicting implications for potential therapeutic agents. Expert Rev Anti Infect Ther (2012) 0.83

Dendritic cells and parasites: from recognition and activation to immune response instruction. Semin Immunopathol (2016) 0.82

Ageing and Toll-like receptor expression by innate immune cells in chronic human schistosomiasis. Clin Exp Immunol (2007) 0.82

The bacterial preparation OK432 induces IL-12p70 secretion in human dendritic cells in a TLR3 dependent manner. PLoS One (2012) 0.81

TLRs, Treg, and B Cells, an Interplay of Regulation during Helminth Infection. Front Immunol (2012) 0.81

Cofactors that may influence vaccine responses. Curr Opin HIV AIDS (2010) 0.80

The 3' CCACCA sequence of tRNAAla(UGC) is the motif that is important in inducing Th1-like immune response, and this motif can be recognized by Toll-like receptor 3. Clin Vaccine Immunol (2006) 0.79

Does helminth activation of toll-like receptors modulate immune response in multiple sclerosis patients? Front Cell Infect Microbiol (2012) 0.79

Schistosoma mansoni soluble egg antigens enhance Listeria monocytogenes vector HIV-1 vaccine induction of cytotoxic T cells. Clin Vaccine Immunol (2014) 0.78

Molecular characterization of coding sequences and analysis of Toll-like receptor 3 mRNA expression in water buffalo (Bubalus bubalis) and nilgai (Boselaphus tragocamelus). Immunogenetics (2006) 0.78

Future directions of clinical laboratory evaluation of pregnancy. Cell Mol Immunol (2014) 0.78

CD14 influences host immune responses and alternative activation of macrophages during Schistosoma mansoni infection. Infect Immun (2014) 0.78

Notch Signaling in Inflammation-Induced Preterm Labor. Sci Rep (2015) 0.78

Host parasite communications-Messages from helminths for the immune system: Parasite communication and cell-cell interactions. Mol Biochem Parasitol (2016) 0.77

Network Analysis of the Systemic Response to Fasciola hepatica Infection in Sheep Reveals Changes in Fibrosis, Apoptosis, Toll-Like Receptors 3/4, and B Cell Function. Front Immunol (2017) 0.75

Articles by these authors

Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy. Nat Med (2007) 13.90

Insulin needs after CD3-antibody therapy in new-onset type 1 diabetes. N Engl J Med (2005) 10.16

Generation of gut-homing IgA-secreting B cells by intestinal dendritic cells. Science (2006) 5.31

Identification of an IL-17-producing NK1.1(neg) iNKT cell population involved in airway neutrophilia. J Exp Med (2007) 4.47

The European dimension for the mouse genome mutagenesis program. Nat Genet (2004) 3.84

A sequence-oriented comparison of gene expression measurements across different hybridization-based technologies. Nat Biotechnol (2006) 3.68

Development of a cross-platform biomarker signature to detect renal transplant tolerance in humans. J Clin Invest (2010) 3.41

Aneuploidy underlies rapid adaptive evolution of yeast cells deprived of a conserved cytokinesis motor. Cell (2008) 3.26

A novel dendritic cell subset involved in tumor immunosurveillance. Nat Med (2006) 3.21

Detection of prokaryotic mRNA signifies microbial viability and promotes immunity. Nature (2011) 2.93

IRF4 transcription factor-dependent CD11b+ dendritic cells in human and mouse control mucosal IL-17 cytokine responses. Immunity (2013) 2.69

IL-10 is an important mediator of the enhanced susceptibility to pneumococcal pneumonia after influenza infection. J Immunol (2004) 2.59

Activation of invariant NKT cells by toll-like receptor 9-stimulated dendritic cells requires type I interferon and charged glycosphingolipids. Immunity (2007) 2.58

Toll-like receptor 4 expression is required to control chronic Mycobacterium tuberculosis infection in mice. J Immunol (2002) 2.17

CD14 regulates the dendritic cell life cycle after LPS exposure through NFAT activation. Nature (2009) 2.13

Statistical similarities between transcriptomics and quantitative shotgun proteomics data. Mol Cell Proteomics (2007) 2.05

Contribution of IL-17-producing gamma delta T cells to the efficacy of anticancer chemotherapy. J Exp Med (2011) 2.04

Complexity and complementarity of outer membrane protein A recognition by cellular and humoral innate immunity receptors. Immunity (2005) 1.86

Lymphocytic variant hypereosinophilic syndromes. Immunol Allergy Clin North Am (2007) 1.85

Implications for invariant natural killer T cell ligands due to the restricted presence of isoglobotrihexosylceramide in mammals. Proc Natl Acad Sci U S A (2007) 1.84

Delayed correlation of mRNA and protein expression in rapamycin-treated cells and a role for Ggc1 in cellular sensitivity to rapamycin. Mol Cell Proteomics (2009) 1.76

Impaired responses to toll-like receptor 4 and toll-like receptor 3 ligands in human cord blood. J Autoimmun (2003) 1.74

Direct bacterial protein PAMP recognition by human NK cells involves TLRs and triggers alpha-defensin production. Blood (2004) 1.71

A defect in nucleosome remodeling prevents IL-12(p35) gene transcription in neonatal dendritic cells. J Exp Med (2004) 1.71

Critical influence of natural regulatory CD25+ T cells on the fate of allografts in the absence of immunosuppression. Transplantation (2005) 1.66

How microorganisms tip the balance between interleukin-12 family members. Nat Rev Immunol (2008) 1.65

A contribution of mouse dendritic cell-derived IL-2 for NK cell activation. J Exp Med (2004) 1.59

IL-18 induces PD-1-dependent immunosuppression in cancer. Cancer Res (2011) 1.59

IL-23 up-regulates IL-10 and induces IL-17 synthesis by polyclonally activated naive T cells in human. Eur J Immunol (2005) 1.59

Early IL-2 production by mouse dendritic cells is the result of microbial-induced priming. J Immunol (2003) 1.59

TPL-2 negatively regulates interferon-beta production in macrophages and myeloid dendritic cells. J Exp Med (2009) 1.58

Early immunosuppression withdrawal after living donor liver transplantation and donor stem cell infusion. Liver Transpl (2006) 1.57

A power law global error model for the identification of differentially expressed genes in microarray data. BMC Bioinformatics (2004) 1.56

Cytokine mRNA quantification by real-time PCR. J Immunol Methods (2002) 1.56

Activation of the prostaglandin D2 receptor DP2/CRTH2 increases allergic inflammation in mouse. J Immunol (2005) 1.54

Hypereosinophilic syndromes. Orphanet J Rare Dis (2007) 1.53

Peroxisome proliferator-activated receptors alpha and gamma down-regulate allergic inflammation and eosinophil activation. J Exp Med (2003) 1.53

Molecular phylogenies of Blastocystis isolates from different hosts: implications for genetic diversity, identification of species, and zoonosis. J Clin Microbiol (2005) 1.52

Activation of the D prostanoid 1 receptor suppresses asthma by modulation of lung dendritic cell function and induction of regulatory T cells. J Exp Med (2007) 1.52

Proteinase 3 on apoptotic cells disrupts immune silencing in autoimmune vasculitis. J Clin Invest (2015) 1.43

Systemic Toll-like receptor stimulation suppresses experimental allergic asthma and autoimmune diabetes in NOD mice. PLoS One (2010) 1.43

Human cytomegalovirus elicits fetal gammadelta T cell responses in utero. J Exp Med (2010) 1.39

Acquisition of adult-like TLR4 and TLR9 responses during the first year of life. PLoS One (2010) 1.37

Monophosphoryl lipid A activates both human dendritic cells and T cells. J Immunol (2002) 1.36

Schistosomes: the road from host-parasite interactions to vaccines in clinical trials. Trends Parasitol (2005) 1.36

Karyotypic determinants of chromosome instability in aneuploid budding yeast. PLoS Genet (2012) 1.36

Toll-like receptor 2 (TLR2) and TLR4 differentially activate human mast cells. Eur J Immunol (2003) 1.35

Interleukin-22 is produced by invariant natural killer T lymphocytes during influenza A virus infection: potential role in protection against lung epithelial damages. J Biol Chem (2012) 1.35

Preferential production of the IL-12(p40)/IL-23(p19) heterodimer by dendritic cells from human newborns. Eur J Immunol (2006) 1.35

Peroxisome proliferator-activated receptor gamma is expressed in airways and inhibits features of airway remodeling in a mouse asthma model. J Allergy Clin Immunol (2004) 1.34

A critical role for Syk protein tyrosine kinase in Fc receptor-mediated antigen presentation and induction of dendritic cell maturation. J Immunol (2003) 1.34

High serum thymus and activation-regulated chemokine levels in the lymphocytic variant of the hypereosinophilic syndrome. J Allergy Clin Immunol (2002) 1.34

Critical role of regulatory T cells in Th17-mediated minor antigen-disparate rejection. J Immunol (2010) 1.34

Blood plasmacytoid dendritic cell responses to CpG oligodeoxynucleotides are impaired in human newborns. Blood (2003) 1.32

The presence of four iron-containing superoxide dismutase isozymes in trypanosomatidae: characterization, subcellular localization, and phylogenetic origin in Trypanosoma brucei. Free Radic Biol Med (2005) 1.31

Opposing effects of toll-like receptor (TLR3) signaling in tumors can be therapeutically uncoupled to optimize the anticancer efficacy of TLR3 ligands. Cancer Res (2010) 1.31

Human gamma delta T cells induce dendritic cell maturation. Clin Immunol (2002) 1.29

The Trypanosoma cruzi Tc52-released protein induces human dendritic cell maturation, signals via Toll-like receptor 2, and confers protection against lethal infection. J Immunol (2002) 1.28

Nicotine protects kidney from renal ischemia/reperfusion injury through the cholinergic anti-inflammatory pathway. PLoS One (2007) 1.27

Trypanosomiasis-induced B cell apoptosis results in loss of protective anti-parasite antibody responses and abolishment of vaccine-induced memory responses. PLoS Pathog (2008) 1.27

Induction of FOXP3-expressing regulatory CD4pos T cells by human mature autologous dendritic cells. Eur J Immunol (2004) 1.27

The scavenger receptor MARCO mediates cytoskeleton rearrangements in dendritic cells and microglia. Blood (2003) 1.27

IL-27 synthesis induced by TLR ligation critically depends on IFN regulatory factor 3. J Immunol (2007) 1.26

Mepolizumab as a corticosteroid-sparing agent in lymphocytic variant hypereosinophilic syndrome. J Allergy Clin Immunol (2010) 1.25

The hypereosinophilic syndrome revisited. Annu Rev Med (2001) 1.25

IL-17A-producing gammadelta T and Th17 lymphocytes mediate lung inflammation but not fibrosis in experimental silicosis. J Immunol (2010) 1.25

Dendritic cell-derived IL-2 production is regulated by IL-15 in humans and in mice. Blood (2004) 1.24

Interferon regulatory factor 7-mediated responses are defective in cord blood plasmacytoid dendritic cells. Eur J Immunol (2008) 1.24

AMDA: an R package for the automated microarray data analysis. BMC Bioinformatics (2006) 1.23

Vaccination and autoimmune disease: what is the evidence? Lancet (2003) 1.22

Activation of peroxisome proliferator-activated receptor-gamma in dendritic cells inhibits the development of eosinophilic airway inflammation in a mouse model of asthma. Am J Pathol (2004) 1.22

Dendritic cell regulation of immune responses: a new role for interleukin 2 at the intersection of innate and adaptive immunity. EMBO J (2003) 1.22

Multiple pathways to allograft rejection. Transplantation (2002) 1.21

Human eosinophils express and release IL-13 following CD28-dependent activation. J Leukoc Biol (2002) 1.21

Transforming growth factor-beta and natural killer T-cells are involved in the protective effect of a bacterial extract on type 1 diabetes. Diabetes (2006) 1.21

Egfl7 promotes tumor escape from immunity by repressing endothelial cell activation. Cancer Res (2011) 1.20

Outer membrane protein A (OmpA): a new pathogen-associated molecular pattern that interacts with antigen presenting cells-impact on vaccine strategies. Vaccine (2002) 1.20

Interferon regulatory factor 3 is involved in Toll-like receptor 4 (TLR4)- and TLR3-induced IL-12p35 gene activation. Blood (2005) 1.20

Interleukin-22 reduces lung inflammation during influenza A virus infection and protects against secondary bacterial infection. J Virol (2013) 1.19

Human IL-12(p35) gene activation involves selective remodeling of a single nucleosome within a region of the promoter containing critical Sp1-binding sites. Blood (2003) 1.19