Published in J Mol Biol on November 19, 2004
Mammalian twinfilin sequesters ADP-G-actin and caps filament barbed ends: implications in motility. EMBO J (2006) 1.31
Coactosin-like 1 antagonizes cofilin to promote lamellipodial protrusion at the immune synapse. PLoS One (2014) 0.80
EhCoactosin stabilizes actin filaments in the protist parasite Entamoeba histolytica. PLoS Pathog (2014) 0.79
CDD: a curated Entrez database of conserved domain alignments. Nucleic Acids Res (2003) 14.38
Database resources of the National Center for Biotechnology Information. Nucleic Acids Res (2009) 12.51
Database resources of the National Center for Biotechnology Information. Nucleic Acids Res (2010) 10.97
Database resources of the National Center for Biotechnology Information. Nucleic Acids Res (2011) 8.62
MMDB: Entrez's 3D-structure database. Nucleic Acids Res (2003) 6.14
Mortality among hospitalized Medicare beneficiaries in the first 2 years following ACGME resident duty hour reform. JAMA (2007) 5.81
Loss of integrin alpha(v)beta8 on dendritic cells causes autoimmunity and colitis in mice. Nature (2007) 4.94
A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response. Nature (2012) 4.08
Loss of integrin alpha(v)beta6-mediated TGF-beta activation causes Mmp12-dependent emphysema. Nature (2003) 4.02
PubChem as a public resource for drug discovery. Drug Discov Today (2010) 3.40
Failure-to-rescue: comparing definitions to measure quality of care. Med Care (2007) 3.16
A new UAG-encoded residue in the structure of a methanogen methyltransferase. Science (2002) 3.11
One-unit versus two-unit cord-blood transplantation for hematologic cancers. N Engl J Med (2014) 3.07
IL-17A produced by αβ T cells drives airway hyper-responsiveness in mice and enhances mouse and human airway smooth muscle contraction. Nat Med (2012) 2.47
Structures and receptor binding of hemagglutinins from human-infecting H7N9 influenza viruses. Science (2013) 2.34
MMDB: 3D structures and macromolecular interactions. Nucleic Acids Res (2011) 2.06
Did duty hour reform lead to better outcomes among the highest risk patients? J Gen Intern Med (2009) 1.92
The ventricular volume variability study of the Pediatric Heart Network: study design and impact of beat averaging and variable type on the reproducibility of echocardiographic measurements in children with chronic dilated cardiomyopathy. J Am Soc Echocardiogr (2012) 1.82
Structure-based virtual screening for drug discovery: a problem-centric review. AAPS J (2012) 1.68
Crystal structures of the extracellular domain of LRP6 and its complex with DKK1. Nat Struct Mol Biol (2011) 1.68
Clinical features and factors associated with severity and fatality among patients with severe fever with thrombocytopenia syndrome Bunyavirus infection in Northeast China. PLoS One (2013) 1.67
Aggressive treatment style and surgical outcomes. Health Serv Res (2010) 1.66
Hospital teaching intensity, patient race, and surgical outcomes. Arch Surg (2009) 1.65
Phosphorylation of human Argonaute proteins affects small RNA binding. Nucleic Acids Res (2010) 1.64
SUMO1 modification of PTEN regulates tumorigenesis by controlling its association with the plasma membrane. Nat Commun (2012) 1.58
Crystallographic studies of human MitoNEET. J Biol Chem (2007) 1.57
Nanosized zinc oxide particles induce neural stem cell apoptosis. Nanotechnology (2009) 1.56
Structural basis for methylarginine-dependent recognition of Aubergine by Tudor. Genes Dev (2010) 1.52
Myosin VI undergoes cargo-mediated dimerization. Cell (2009) 1.47
Cytokine and chemokine levels in patients with severe fever with thrombocytopenia syndrome virus. PLoS One (2012) 1.45
A covalent approach for site-specific RNA labeling in Mammalian cells. Angew Chem Int Ed Engl (2015) 1.41
Regulation of DNA repair fidelity by molecular checkpoints: "gates" in DNA polymerase beta's substrate selection. Biochemistry (2006) 1.40
The mechanisms of human hotdog-fold thioesterase 2 (hTHEM2) substrate recognition and catalysis illuminated by a structure and function based analysis. Biochemistry (2009) 1.40
A survey of across-target bioactivity results of small molecules in PubChem. Bioinformatics (2009) 1.39
lncRNA H19/miR-675 axis represses prostate cancer metastasis by targeting TGFBI. FEBS J (2014) 1.36
LGN/mInsc and LGN/NuMA complex structures suggest distinct functions in asymmetric cell division for the Par3/mInsc/LGN and Gαi/LGN/NuMA pathways. Mol Cell (2011) 1.28
Structure-based cleavage mechanism of Thermus thermophilus Argonaute DNA guide strand-mediated DNA target cleavage. Proc Natl Acad Sci U S A (2013) 1.26
Developing and validating predictive decision tree models from mining chemical structural fingerprints and high-throughput screening data in PubChem. BMC Bioinformatics (2008) 1.24
A novel method for mining highly imbalanced high-throughput screening data in PubChem. Bioinformatics (2009) 1.19
Crystal structure of human eIF3k, the first structure of eIF3 subunits. J Biol Chem (2004) 1.18
Domain-swapped dimerization of ZO-1 PDZ2 generates specific and regulatory connexin43-binding sites. EMBO J (2008) 1.18
Structure of MyTH4-FERM domains in myosin VIIa tail bound to cargo. Science (2011) 1.17
Autoinhibition of UNC5b revealed by the cytoplasmic domain structure of the receptor. Mol Cell (2009) 1.17
Variability of M-mode versus two-dimensional echocardiography measurements in children with dilated cardiomyopathy. Pediatr Cardiol (2013) 1.17
Structural insights into protein arginine symmetric dimethylation by PRMT5. Proc Natl Acad Sci U S A (2011) 1.14
The αvβ6 integrin modulates airway hyperresponsiveness in mice by regulating intraepithelial mast cells. J Clin Invest (2012) 1.13
Identifying compound-target associations by combining bioactivity profile similarity search and public databases mining. J Chem Inf Model (2011) 1.12
Structural basis for the function of DCN-1 in protein Neddylation. J Biol Chem (2007) 1.11
Structural insights into the redox-regulated dynamic conformations of human protein disulfide isomerase. Antioxid Redox Signal (2012) 1.11
Tyr26 phosphorylation of PGAM1 provides a metabolic advantage to tumours by stabilizing the active conformation. Nat Commun (2013) 1.08
Molecular determinants for ATP-binding in proteins: a data mining and quantum chemical analysis. J Mol Biol (2004) 1.07
Human thioesterase superfamily member 2 (hTHEM2) is co-localized with beta-tubulin onto the microtubule. Biochem Biophys Res Commun (2006) 1.07
Dietary quality 1 year after diagnosis of coronary heart disease. J Am Diet Assoc (2008) 1.06
Structural insights into a novel histone demethylase PHF8. Cell Res (2010) 1.05
PRMT5 regulates Golgi apparatus structure through methylation of the golgin GM130. Cell Res (2010) 1.05
Structure of the alpha2epsilon2 Ni-dependent CO dehydrogenase component of the Methanosarcina barkeri acetyl-CoA decarbonylase/synthase complex. Proc Natl Acad Sci U S A (2008) 1.05
Seeing the process of histidine phosphorylation in human bisphosphoglycerate mutase. J Biol Chem (2006) 1.04
Identification of microRNA transcriptome involved in human natural killer cell activation. Immunol Lett (2012) 1.04
The role of intestinal mucosa injury induced by intra-abdominal hypertension in the development of abdominal compartment syndrome and multiple organ dysfunction syndrome. Crit Care (2013) 1.03
In Vivo evaluation of a PAMAM-cystamine-(Gd-DO3A) conjugate as a biodegradable macromolecular MRI contrast agent. Exp Biol Med (Maywood) (2007) 1.03
DNA polymerase beta catalysis: are different mechanisms possible? J Am Chem Soc (2007) 1.02
Extranodal follicular dendritic cell sarcoma in mesentery: A case report. Oncol Lett (2011) 1.01
Binary classification of aqueous solubility using support vector machines with reduction and recombination feature selection. J Chem Inf Model (2011) 1.00
Crystal structure of the C-terminal domain of S.cerevisiae eIF5. J Mol Biol (2006) 1.00
miR-146a functions as a tumor suppressor in prostate cancer by targeting Rac1. Prostate (2014) 1.00
The impact of resident duty hour reform on hospital readmission rates among Medicare beneficiaries. J Gen Intern Med (2010) 0.99
Crystal structure of human thioesterase superfamily member 2. Biochem Biophys Res Commun (2006) 0.99
Structural basis of the myosin X PH1(N)-PH2-PH1(C) tandem as a specific and acute cellular PI(3,4,5)P(3) sensor. Mol Biol Cell (2011) 0.96
The INAD scaffold is a dynamic, redox-regulated modulator of signaling in the Drosophila eye. Cell (2011) 0.96
Antiparallel coiled-coil-mediated dimerization of myosin X. Proc Natl Acad Sci U S A (2012) 0.96
The RRM domain of human fused in sarcoma protein reveals a non-canonical nucleic acid binding site. Biochim Biophys Acta (2012) 0.95
Phosphorylation of DCC by ERK2 is facilitated by direct docking of the receptor P1 domain to the kinase. Structure (2010) 0.95
Crystal structures of E. coli laccase CueO at different copper concentrations. Biochem Biophys Res Commun (2006) 0.95
Investigating the correlations among the chemical structures, bioactivity profiles and molecular targets of small molecules. Bioinformatics (2010) 0.94
Enzymatically inactive adenylate kinase 4 interacts with mitochondrial ADP/ATP translocase. Int J Biochem Cell Biol (2008) 0.94
Crystal structure of human B-type phosphoglycerate mutase bound with citrate. Biochem Biophys Res Commun (2005) 0.94
Photoelectrochemical detection of glutathione by IrO2-hemin-TiO2 nanowire arrays. Nano Lett (2013) 0.93
Inhibitory effect of cucurbitacin E on pancreatic cancer cells growth via STAT3 signaling. J Cancer Res Clin Oncol (2009) 0.93
Identification of a glyphosate-resistant mutant of rice 5-enolpyruvylshikimate 3-phosphate synthase using a directed evolution strategy. Plant Physiol (2005) 0.93
Supramodular nature of GRIP1 revealed by the structure of its PDZ12 tandem in complex with the carboxyl tail of Fras1. J Mol Biol (2007) 0.93
SUMOylation of Grb2 enhances the ERK activity by increasing its binding with Sos1. Mol Cancer (2014) 0.92
Carbon nanodots featuring efficient FRET for real-time monitoring of drug delivery and two-photon imaging. Adv Mater (2013) 0.92
Unique structural characteristics of peptide deformylase from pathogenic bacterium Leptospira interrogans. J Mol Biol (2004) 0.92
PtdIns(4)P regulates retromer-motor interaction to facilitate dynein-cargo dissociation at the trans-Golgi network. Nat Cell Biol (2013) 0.92
Internally deleted human tRNA synthetase suggests evolutionary pressure for repurposing. Structure (2012) 0.91
Diversification and evolution of the avirulence gene AVR-Pita1 in field isolates of Magnaporthe oryzae. Fungal Genet Biol (2010) 0.91
Enzymatic properties of a new peptide deformylase from pathogenic bacterium Leptospira interrogans. Biochem Biophys Res Commun (2002) 0.91
Teaching hospital five-year mortality trends in the wake of duty hour reforms. J Gen Intern Med (2013) 0.91
Crystal structure of human guanosine monophosphate reductase 2 (GMPR2) in complex with GMP. J Mol Biol (2005) 0.91