Published in J Neurosci Res on December 27, 2004
In vivo evidence for alcohol-induced neurochemical changes in rat brain without protracted withdrawal, pronounced thiamine deficiency, or severe liver damage. Neuropsychopharmacology (2008) 1.03
Metabolic and structural role of thiamine in nervous tissues. Cell Mol Neurobiol (2008) 0.84
Associations between in vivo neuroimaging and postmortem brain cytokine markers in a rodent model of Wernicke's encephalopathy. Exp Neurol (2014) 0.77
Alcohol's Effects on the Brain: Neuroimaging Results in Humans and Animal Models. Alcohol Res (2017) 0.75
Novel mechanisms of protection against acetaminophen hepatotoxicity in mice by glutathione and N-acetylcysteine. Hepatology (2010) 2.15
Neurobiology of ammonia. Prog Neurobiol (2002) 1.84
Excitotoxic mechanisms and the role of astrocytic glutamate transporters in traumatic brain injury. Neurochem Int (2006) 1.81
Effects of hypothermia on brain glucose metabolism in acute liver failure: a H/C-nuclear magnetic resonance study. Gastroenterology (2003) 1.60
Alterations in expression of genes coding for proteins of the neurovascular unit in ischemic liver failure. Neurochem Int (2009) 1.55
Effect of albumin dialysis on intracranial pressure increase in pigs with acute liver failure: a randomized study. Crit Care Med (2006) 1.50
Perispinal etanercept for post-stroke neurological and cognitive dysfunction: scientific rationale and current evidence. CNS Drugs (2014) 1.49
Increased brain serotonin turnover correlates with the degree of shunting and hyperammonemia in rats following variable portal vein stenosis. J Hepatol (2004) 1.44
L-ornithine and phenylacetate synergistically produce sustained reduction in ammonia and brain water in cirrhotic rats. Hepatology (2009) 1.25
Update of cell damage mechanisms in thiamine deficiency: focus on oxidative stress, excitotoxicity and inflammation. Alcohol Alcohol (2009) 1.11
Cerebral inflammation contributes to encephalopathy and brain edema in acute liver failure: protective effect of minocycline. J Neurochem (2009) 1.08
Neurobiological characterization of an azoxymethane mouse model of acute liver failure. Neurochem Int (2006) 1.07
Ammonia induces MK-801-sensitive nitration and phosphorylation of protein tyrosine residues in rat astrocytes. FASEB J (2002) 1.07
Manganese neurotoxicity: an update of pathophysiologic mechanisms. Metab Brain Dis (2002) 1.06
Energy metabolism in astrocytes and neurons treated with manganese: relation among cell-specific energy failure, glucose metabolism, and intercellular trafficking using multinuclear NMR-spectroscopic analysis. J Cereb Blood Flow Metab (2003) 1.06
Direct evidence for central proinflammatory mechanisms in rats with experimental acute liver failure: protective effect of hypothermia. J Cereb Blood Flow Metab (2009) 1.06
Mild hypothermia attenuates liver injury and improves survival in mice with acetaminophen toxicity. Gastroenterology (2006) 1.04
Endotoxemia produces coma and brain swelling in bile duct ligated rats. Hepatology (2007) 1.03
IL-1 or TNF receptor gene deletion delays onset of encephalopathy and attenuates brain edema in experimental acute liver failure. Neurochem Int (2009) 1.01
Modeling neurodegenerative disease pathophysiology in thiamine deficiency: consequences of impaired oxidative metabolism. Neurochem Int (2010) 1.00
N-acetylcysteine attenuates cerebral complications of non-acetaminophen-induced acute liver failure in mice: antioxidant and anti-inflammatory mechanisms. Metab Brain Dis (2010) 1.00
Decreased beta-actin mRNA expression in hyperglycemic focal cerebral ischemia in the rat. Neurosci Lett (2004) 0.98
Direct molecular and spectroscopic evidence for increased ammonia removal capacity of skeletal muscle in acute liver failure. J Hepatol (2006) 0.97
Brain energy metabolism in a sub-acute rat model of manganese neurotoxicity: an ex vivo nuclear magnetic resonance study using [1-13C]glucose. Neurotoxicology (2004) 0.93
Selective increase of brain lactate synthesis in experimental acute liver failure: results of a [H-C] nuclear magnetic resonance study. Hepatology (2003) 0.93
Pathogenesis of hepatic encephalopathy: new insights from neuroimaging and molecular studies. J Hepatol (2003) 0.93
Mice deficient in Neu4 sialidase exhibit abnormal ganglioside catabolism and lysosomal storage. Hum Mol Genet (2008) 0.93
Role of mitochondrial dysfunction and oxidative stress in the pathogenesis of selective neuronal loss in Wernicke's encephalopathy. Mol Neurobiol (2005) 0.92
Mitochondrial dysfunction in acute hyperammonemia. Neurochem Int (2002) 0.92
The neurosteroid system: implication in the pathophysiology of hepatic encephalopathy. Neurochem Int (2007) 0.91
Pathogenesis of hepatic encephalopathy and brain edema in acute liver failure: role of glutamine redefined. Neurochem Int (2012) 0.91
Early loss of the glutamate transporter splice-variant GLT-1v in rat cerebral cortex following lateral fluid-percussion injury. Glia (2005) 0.91
Inflammatory cascades driven by tumor necrosis factor-alpha play a major role in the progression of acute liver failure and its neurological complications. PLoS One (2012) 0.91
Acute liver failure: a critical appraisal of available animal models. Metab Brain Dis (2005) 0.90
MRL/lpr mice have alterations in brain metabolism as shown with [1H-13C] NMR spectroscopy. Neurochem Int (2005) 0.89
Increased brain endothelial nitric oxide synthase expression in thiamine deficiency: relationship to selective vulnerability. Neurochem Int (2004) 0.87
Loss of expression of glial fibrillary acidic protein in acute hyperammonemia. Neurochem Int (2002) 0.87
Liver-brain proinflammatory signalling in acute liver failure: role in the pathogenesis of hepatic encephalopathy and brain edema. Metab Brain Dis (2012) 0.87
Mild hypothermia in the prevention of brain edema in acute liver failure: mechanisms and clinical prospects. Metab Brain Dis (2002) 0.86
Ammonia and proinflammatory cytokines modify expression of genes coding for astrocytic proteins implicated in brain edema in acute liver failure. Metab Brain Dis (2010) 0.86
Organic osmolytes in hyponatremia and ammonia toxicity. Metab Brain Dis (2010) 0.86
Keeping cool in acute liver failure: rationale for the use of mild hypothermia. J Hepatol (2005) 0.86
Early, transient increase in complexin I and complexin II in the cerebral cortex following traumatic brain injury is attenuated by N-acetylcysteine. J Neurotrauma (2006) 0.86
Gene expression changes in thalamus and inferior colliculus associated with inflammation, cellular stress, metabolism and structural damage in thiamine deficiency. Eur J Neurosci (2006) 0.86
Altered expression of tight junction proteins and matrix metalloproteinases in thiamine-deficient mouse brain. Neurochem Int (2009) 0.86
The brain glutamate system in liver failure. J Neurochem (2006) 0.85
Region selective alterations of soluble guanylate cyclase content and modulation in brain of cirrhotic patients. Hepatology (2002) 0.85
Increased expression of "peripheral-type" benzodiazepine receptors in human temporal lobe epilepsy: implications for PET imaging of hippocampal sclerosis. Metab Brain Dis (2002) 0.85
Minocycline attenuates oxidative/nitrosative stress and cerebral complications of acute liver failure in rats. Neurochem Int (2009) 0.85
Dehydroascorbic acid normalizes several markers of oxidative stress and inflammation in acute hyperglycemic focal cerebral ischemia in the rat. Neurochem Int (2005) 0.85
Normal coupling of brain benzodiazepine and neurosteroid modulatory sites on the GABA-A receptor complex in human hepatic encephalopathy. Neurochem Int (2003) 0.84
Manganese distribution in the brain and neurobehavioral changes following inhalation exposure of rats to three chemical forms of manganese. Neurotoxicology (2004) 0.84
Increased levels of pregnenolone and its neuroactive metabolite allopregnanolone in autopsied brain tissue from cirrhotic patients who died in hepatic coma. Neurochem Int (2006) 0.84
Lipopolysaccharide precipitates hepatic encephalopathy and increases blood-brain barrier permeability in mice with acute liver failure. Liver Int (2013) 0.83
Region-selective alterations of glucose oxidation and amino acid synthesis in the thiamine-deficient rat brain: a re-evaluation using 1H/13C nuclear magnetic resonance spectroscopy. J Neurochem (2008) 0.83
Increased brain concentrations of a neuroinhibitory steroid in human hepatic encephalopathy. Ann Neurol (2005) 0.83
Selective increase of neuronal cyclooxygenase-2 (COX-2) expression in vulnerable brain regions of rats with experimental Wernicke's encephalopathy: effect of nimesulide. Metab Brain Dis (2008) 0.83
Antioxidant and anti-inflammatory effects of mild hypothermia in the attenuation of liver injury due to azoxymethane toxicity in the mouse. Metab Brain Dis (2010) 0.83
Selective alterations of brain osmolytes in acute liver failure: protective effect of mild hypothermia. Brain Res (2004) 0.83
Increased Na, K-ATPase alpha2 isoform gene expression by ammonia in astrocytes and in brain in vivo. Neurochem Int (2010) 0.83
Pathophysiology of hepatic encephalopathy: a new look at GABA from the molecular standpoint. Metab Brain Dis (2004) 0.82
Nmr spectroscopic analysis of regional brain energy metabolism in manganese neurotoxicity. Glia (2007) 0.82
N-acetylcysteine attenuates early induction of heme oxygenase-1 following traumatic brain injury. Brain Res (2005) 0.82
Induction of astrocytic cyclooxygenase-2 in epileptic patients with hippocampal sclerosis. Neurochem Int (2003) 0.82
Selectively increased expression of the astrocytic/endothelial glucose transporter protein GLUT1 in acute liver failure. Glia (2006) 0.82
Sustained hydrogen peroxide stress decreases lactate production by cultured astrocytes. J Neurosci Res (2009) 0.82
Up-regulation of caveolin-1 and blood-brain barrier breakdown are attenuated by N-acetylcysteine in thiamine deficiency. Neurochem Int (2010) 0.81
Reduced brain levels of DHEAS in hepatic coma patients: significance for increased GABAergic tone in hepatic encephalopathy. Neurochem Int (2012) 0.81
Expression of superoxide dismutase in hyperglycemic focal cerebral ischemia in the rat. Neurochem Int (2004) 0.81
Mechanisms of brain edema in acute liver failure and impact of novel therapeutic interventions. Neurol Res (2007) 0.81
Microglial activation is a major contributor to neurologic dysfunction in thiamine deficiency. Biochem Biophys Res Commun (2010) 0.81
Evidence for oxidative/nitrosative stress in the pathogenesis of hepatic encephalopathy. Metab Brain Dis (2010) 0.80
Role of nutrition in the management of hepatic encephalopathy in end-stage liver failure. J Nutr Metab (2010) 0.80
The "peripheral-type" benzodiazepine (omega 3) receptor in hyperammonemic disorders. Neurochem Int (2002) 0.80
Acute liver failure-induced hepatic encephalopathy s associated with changes in microRNA expression rofiles in cerebral cortex of the mouse [corrected]. Metab Brain Dis (2014) 0.80
An interaction between benzodiazepines and neuroactive steroids at GABA A receptors in cultured hippocampal neurons. Neurochem Int (2006) 0.80
Assessment of bioaccumulation, neuropathology, and neurobehavior following subchronic (90 days) inhalation in Sprague-Dawley rats exposed to manganese phosphate. Toxicol Appl Pharmacol (2002) 0.80
The biosynthesis of ascorbate protects isolated rat hepatocytes from cumene hydroperoxide-mediated oxidative stress. Free Radic Biol Med (2005) 0.80
Mild hypothermia prevents brain edema and attenuates up-regulation of the astrocytic benzodiazepine receptor in experimental acute liver failure. J Hepatol (2005) 0.79
Expression of astrocytic genes coding for proteins implicated in neural excitation and brain edema is altered after acute liver failure. J Neurochem (2013) 0.79
Increased brain concentrations of endogenous (non-benzodiazepine) GABA-A receptor ligands in human hepatic encephalopathy. Metab Brain Dis (2004) 0.79
Glutamate transporter EAAT4 is increased in hippocampal astrocytes following lateral fluid-percussion injury in the rat. Brain Res (2007) 0.79
The neurosteroid system: an emerging therapeutic target for hepatic encephalopathy. Metab Brain Dis (2007) 0.79
Mild hypothermia for the treatment of acute liver failure--what are we waiting for? Nat Clin Pract Gastroenterol Hepatol (2007) 0.79
Primary cultures of rat astrocytes respond to thiamine deficiency-induced swelling by downregulating aquaporin-4 levels. Neurosci Lett (2004) 0.79
Selective alterations of brain dopamine D(2) receptor binding in cirrhotic patients: results of a (11)C-N-methylspiperone PET study. Metab Brain Dis (2008) 0.78
Hypothermia attenuates oxidative/nitrosative stress, encephalopathy and brain edema in acute (ischemic) liver failure. Neurochem Int (2009) 0.78
Impaired oxidation of branched-chain amino acids in the medial thalamus of thiamine-deficient rats. Metab Brain Dis (2008) 0.78