Published in FASEB J on December 01, 2004
Isoform-selective effects of the depletion of ADP-ribosylation factors 1-5 on membrane traffic. Mol Biol Cell (2005) 2.21
Discovery of Novel DENN Proteins: Implications for the Evolution of Eukaryotic Intracellular Membrane Structures and Human Disease. Front Genet (2012) 2.08
Nomenclature for the human Arf family of GTP-binding proteins: ARF, ARL, and SAR proteins. J Cell Biol (2006) 1.92
Arl2 and Arl3 regulate different microtubule-dependent processes. Mol Biol Cell (2006) 1.71
The Ras protein superfamily: evolutionary tree and role of conserved amino acids. J Cell Biol (2012) 1.50
Joubert syndrome: insights into brain development, cilium biology, and complex disease. Semin Pediatr Neurol (2009) 1.48
Molecular paleontology and complexity in the last eukaryotic common ancestor. Crit Rev Biochem Mol Biol (2013) 1.39
The EGFR-GEP100-Arf6-AMAP1 signaling pathway specific to breast cancer invasion and metastasis. Traffic (2009) 1.31
The microRNA miR-124 controls gene expression in the sensory nervous system of Caenorhabditis elegans. Nucleic Acids Res (2010) 1.22
Toward a model for Arf GTPases as regulators of traffic at the Golgi. FEBS Lett (2009) 1.21
Rab protein evolution and the history of the eukaryotic endomembrane system. Cell Mol Life Sci (2010) 1.15
Comparative genomics uncovers novel structural and functional features of the heterotrimeric GTPase signaling system. Gene (2010) 1.08
The arf-like GTPase Arl8 mediates delivery of endocytosed macromolecules to lysosomes in Caenorhabditis elegans. Mol Biol Cell (2010) 1.05
A bow-tie genetic architecture for morphogenesis suggested by a genome-wide RNAi screen in Caenorhabditis elegans. PLoS Genet (2011) 0.97
Disrupted dorsal neural tube BMP signaling in the cilia mutant Arl13b hnn stems from abnormal Shh signaling. Dev Biol (2011) 0.96
The short coiled-coil domain-containing protein UNC-69 cooperates with UNC-76 to regulate axonal outgrowth and normal presynaptic organization in Caenorhabditis elegans. J Biol (2006) 0.94
Development of a Pacific oyster (Crassostrea gigas) 31,918-feature microarray: identification of reference genes and tissue-enriched expression patterns. BMC Genomics (2011) 0.93
The Arf GAP CNT-2 regulates the apoptotic fate in C. elegans asymmetric neuroblast divisions. Curr Biol (2011) 0.91
The Sec7 guanine nucleotide exchange factor GBF1 regulates membrane recruitment of BIG1 and BIG2 guanine nucleotide exchange factors to the trans-Golgi network (TGN). J Biol Chem (2013) 0.90
The leishmania ARL-1 and Golgi traffic. PLoS One (2008) 0.89
Arf3 is activated uniquely at the trans-Golgi network by brefeldin A-inhibited guanine nucleotide exchange factors. Mol Biol Cell (2010) 0.87
Evolution of Tre-2/Bub2/Cdc16 (TBC) Rab GTPase-activating proteins. Mol Biol Cell (2013) 0.86
Ancient complexity, opisthokont plasticity, and discovery of the 11th subfamily of Arf GAP proteins. Traffic (2013) 0.85
Loss of the transcriptional repressor PAG-3/Gfi-1 results in enhanced neurosecretion that is dependent on the dense-core vesicle membrane protein IDA-1/IA-2. PLoS Genet (2009) 0.83
MARTX effector cross kingdom activation by Golgi-associated ADP-ribosylation factors. Cell Microbiol (2016) 0.81
Asymmetric neuroblast divisions producing apoptotic cells require the cytohesin GRP-1 in Caenorhabditis elegans. Genetics (2014) 0.80
Overexpression of ASAP1 is associated with poor prognosis in epithelial ovarian cancer. Int J Clin Exp Pathol (2013) 0.80
Crosstalk of small GTPases at the Golgi apparatus. Small GTPases (2012) 0.79
ACAP-A/B are ArfGAP homologs in dictyostelium involved in sporulation but not in chemotaxis. PLoS One (2010) 0.79
Requirement of a mitogen-activated protein kinase for appressorium formation and penetration of insect cuticle by the entomopathogenic fungus Beauveria bassiana. Appl Environ Microbiol (2010) 0.79
Structure, organization and evolution of ADP-ribosylation factors in rice and foxtail millet, and their expression in rice. Sci Rep (2016) 0.79
Higher order signaling: ARL2 as regulator of both mitochondrial fusion and microtubule dynamics allows integration of 2 essential cell functions. Small GTPases (2016) 0.78
Arf-like GTPase Arl8: Moving from the periphery to the center of lysosomal biology. Cell Logist (2015) 0.78
Arl13b regulates Shh signaling from both inside and outside the cilium. Mol Biol Cell (2016) 0.77
Negative regulators of the RIG-I-like receptor signaling pathway. Eur J Immunol (2017) 0.76
Haploinsufficiency of the Sec7 guanine nucleotide exchange factor gea1 impairs septation in fission yeast. PLoS One (2013) 0.75
The abundance of the ARL2 GTPase and its GAP, ELMOD2, at mitochondria are modulated by the fusogenic activity of mitofusins and stressors. PLoS One (2017) 0.75
The ARL2 GTPase regulates mitochondrial fusion from the intermembrane space. Cell Logist (2017) 0.75
MicroRNA-responsive 'sensor' transgenes uncover Hox-like and other developmentally regulated patterns of vertebrate microRNA expression. Nat Genet (2004) 6.11
Functional and evolutionary insights from the genomes of three parasitoid Nasonia species. Science (2010) 5.56
Draft genome sequence of the sexually transmitted pathogen Trichomonas vaginalis. Science (2007) 4.89
Dicer function is essential for lung epithelium morphogenesis. Proc Natl Acad Sci U S A (2006) 4.87
Chromatin remodeling in dosage compensation. Annu Rev Genet (2005) 4.62
A bacterial guanine nucleotide exchange factor activates ARF on Legionella phagosomes. Science (2002) 4.49
Distinct stem cell populations regenerate the follicle and interfollicular epidermis. Dev Cell (2005) 3.98
BMP2 activity, although dispensable for bone formation, is required for the initiation of fracture healing. Nat Genet (2006) 3.79
The microRNA miR-196 acts upstream of Hoxb8 and Shh in limb development. Nature (2005) 3.78
Clinical management of metabolic syndrome: report of the American Heart Association/National Heart, Lung, and Blood Institute/American Diabetes Association conference on scientific issues related to management. Circulation (2004) 3.35
Conditional loss of Dicer disrupts cellular and tissue morphogenesis in the cortex and hippocampus. J Neurosci (2008) 3.33
Genetic analysis of the roles of BMP2, BMP4, and BMP7 in limb patterning and skeletogenesis. PLoS Genet (2006) 3.27
Expression of anoctamin 1/TMEM16A by interstitial cells of Cajal is fundamental for slow wave activity in gastrointestinal muscles. J Physiol (2009) 3.02
A C-terminal translocation signal required for Dot/Icm-dependent delivery of the Legionella RalF protein to host cells. Proc Natl Acad Sci U S A (2004) 2.96
A photosynthetic alveolate closely related to apicomplexan parasites. Nature (2008) 2.91
A phylogenomic inventory of meiotic genes; evidence for sex in Giardia and an early eukaryotic origin of meiosis. Curr Biol (2005) 2.86
Epidermal stem cells arise from the hair follicle after wounding. FASEB J (2007) 2.81
MicroRNA expression is required for pancreatic islet cell genesis in the mouse. Diabetes (2007) 2.80
Meiotic pairing and imprinted X chromatin assembly in Caenorhabditis elegans. Nat Genet (2003) 2.77
Essential role for Dicer during skeletal muscle development. Dev Biol (2007) 2.76
A C. elegans LSD1 demethylase contributes to germline immortality by reprogramming epigenetic memory. Cell (2009) 2.74
Podocyte-specific deletion of dicer alters cytoskeletal dynamics and causes glomerular disease. J Am Soc Nephrol (2008) 2.69
The transmembrane protein TMEM16A is required for normal development of the murine trachea. Dev Biol (2008) 2.61
Transmembrane protein 16A (TMEM16A) is a Ca2+-regulated Cl- secretory channel in mouse airways. J Biol Chem (2009) 2.59
Dicer inactivation leads to progressive functional and structural degeneration of the mouse retina. J Neurosci (2008) 2.50
Studies on expression and function of the TMEM16A calcium-activated chloride channel. Proc Natl Acad Sci U S A (2009) 2.33
Dicer loss in striatal neurons produces behavioral and neuroanatomical phenotypes in the absence of neurodegeneration. Proc Natl Acad Sci U S A (2008) 2.32
The calcium-activated chloride channel anoctamin 1 acts as a heat sensor in nociceptive neurons. Nat Neurosci (2012) 2.28
Isoform-selective effects of the depletion of ADP-ribosylation factors 1-5 on membrane traffic. Mol Biol Cell (2005) 2.21
The genomic distribution and function of histone variant HTZ-1 during C. elegans embryogenesis. PLoS Genet (2008) 2.14
Structure and membrane interaction of myristoylated ARF1. Structure (2009) 2.12
Loss of TMEM16A causes a defect in epithelial Ca2+-dependent chloride transport. J Biol Chem (2009) 2.07
LPS induces KH-type splicing regulatory protein-dependent processing of microRNA-155 precursors in macrophages. FASEB J (2009) 1.99
TMEM16A induces MAPK and contributes directly to tumorigenesis and cancer progression. Cancer Res (2012) 1.98
Tmem16A encodes the Ca2+-activated Cl- channel in mouse submandibular salivary gland acinar cells. J Biol Chem (2010) 1.93
Identification of nucleus pulposus precursor cells and notochordal remnants in the mouse: implications for disk degeneration and chordoma formation. Dev Dyn (2008) 1.91
TMEM16 proteins produce volume-regulated chloride currents that are reduced in mice lacking TMEM16A. J Biol Chem (2009) 1.89
Genetic complementation in apicomplexan parasites. Proc Natl Acad Sci U S A (2002) 1.84
Arl2 and Arl3 regulate different microtubule-dependent processes. Mol Biol Cell (2006) 1.71
Degeneration and regeneration of the intervertebral disc: lessons from development. Dis Model Mech (2010) 1.69
An expanded inventory of conserved meiotic genes provides evidence for sex in Trichomonas vaginalis. PLoS One (2007) 1.67
A conserved chromatin architecture marks and maintains the restricted germ cell lineage in worms and flies. Dev Cell (2003) 1.63
The microRNA-processing enzyme dicer maintains juxtaglomerular cells. J Am Soc Nephrol (2010) 1.60
Residual microRNA expression dictates the extent of inner ear development in conditional Dicer knockout mice. Dev Biol (2009) 1.55
Dicer1 is required for differentiation of the mouse male germline. Biol Reprod (2008) 1.52
Arl13b regulates ciliogenesis and the dynamic localization of Shh signaling proteins. Mol Biol Cell (2011) 1.51
Cell lineage analysis demonstrates an endodermal origin of the distal urethra and perineum. Dev Biol (2008) 1.51
Calcium-activated chloride channels (CaCCs) regulate action potential and synaptic response in hippocampal neurons. Neuron (2012) 1.50
Base composition of mononucleotide runs affects DNA polymerase slippage and removal of frameshift intermediates by mismatch repair in Saccharomyces cerevisiae. Mol Cell Biol (2002) 1.49
A Tcf4-positive mesodermal population provides a prepattern for vertebrate limb muscle patterning. Dev Cell (2003) 1.48
Identification of two proteins required for conjunction and regular segregation of achiasmate homologs in Drosophila male meiosis. Cell (2005) 1.44
Munc18 interacting proteins: ADP-ribosylation factor-dependent coat proteins that regulate the traffic of beta-Alzheimer's precursor protein. J Biol Chem (2003) 1.42
Consensus nomenclature for the human ArfGAP domain-containing proteins. J Cell Biol (2008) 1.42
Signs of sex: what we know and how we know it. Trends Ecol Evol (2009) 1.40
The limb bud Shh-Fgf feedback loop is terminated by expansion of former ZPA cells. Science (2004) 1.40
EGO-1, a putative RNA-dependent RNA polymerase, is required for heterochromatin assembly on unpaired dna during C. elegans meiosis. Curr Biol (2005) 1.38
An empirical study of the evolution of virulence under both horizontal and vertical transmission. Evolution (2005) 1.38
NASA: what now? Nature (2011) 1.38
Clinical management of metabolic syndrome: report of the American Heart Association/National Heart, Lung, and Blood Institute/American Diabetes Association conference on scientific issues related to management. Arterioscler Thromb Vasc Biol (2004) 1.38
Sertoli cell Dicer is essential for spermatogenesis in mice. Dev Biol (2008) 1.37
Dynamic structure of membrane-anchored Arf*GTP. Nat Struct Mol Biol (2010) 1.35
The structure of RalF, an ADP-ribosylation factor guanine nucleotide exchange factor from Legionella pneumophila, reveals the presence of a cap over the active site. J Biol Chem (2004) 1.33
Transgenerational epigenetic inheritance: how important is it? Nat Rev Genet (2013) 1.32
Ano1 as a regulator of proliferation. Am J Physiol Gastrointest Liver Physiol (2011) 1.32
Broadly sampled multigene trees of eukaryotes. BMC Evol Biol (2008) 1.32
ELMOD2 is an Arl2 GTPase-activating protein that also acts on Arfs. J Biol Chem (2007) 1.31
Abnormal hair development and apparent follicular transformation to mammary gland in the absence of hedgehog signaling. Dev Cell (2007) 1.31
Genetic analyses reveal a requirement for Dicer1 in the mouse urogenital tract. Mamm Genome (2009) 1.31
Expression of TMEM16 paralogs during murine embryogenesis. Dev Dyn (2008) 1.30
Using a meiosis detection toolkit to investigate ancient asexual "scandals" and the evolution of sex. Bioessays (2008) 1.29
Regulation of heterochromatin assembly on unpaired chromosomes during Caenorhabditis elegans meiosis by components of a small RNA-mediated pathway. PLoS Genet (2009) 1.28
Conditional inactivation of Fgfr1 in mouse defines its role in limb bud establishment, outgrowth and digit patterning. Development (2005) 1.27
Multiphasic and tissue-specific roles of sonic hedgehog in cloacal septation and external genitalia development. Development (2009) 1.23
A role for Set1/MLL-related components in epigenetic regulation of the Caenorhabditis elegans germ line. PLoS Genet (2011) 1.22
Trans-generational epigenetic regulation of C. elegans primordial germ cells. Epigenetics Chromatin (2010) 1.22
Analyses of RNA Polymerase II genes from free-living protists: phylogeny, long branch attraction, and the eukaryotic big bang. Mol Biol Evol (2002) 1.22
BMP4 is dispensable for skeletogenesis and fracture-healing in the limb. J Bone Joint Surg Am (2008) 1.20
Modifications to the C-terminus of Arf1 alter cell functions and protein interactions. Traffic (2010) 1.17
Hedgehog signaling is required for formation of the notochord sheath and patterning of nuclei pulposi within the intervertebral discs. Proc Natl Acad Sci U S A (2011) 1.15
Germline chromatin. WormBook (2006) 1.15
Models for the functions of Arf GAPs. Semin Cell Dev Biol (2010) 1.14
Mouse Disp1 is required in sonic hedgehog-expressing cells for paracrine activity of the cholesterol-modified ligand. Development (2004) 1.13
Characterization of a novel ectodermal signaling center regulating Tbx2 and Shh in the vertebrate limb. Dev Biol (2006) 1.13
Meiosis genes in Daphnia pulex and the role of parthenogenesis in genome evolution. BMC Evol Biol (2009) 1.12
Functional evolution of ADAMTS genes: evidence from analyses of phylogeny and gene organization. BMC Evol Biol (2005) 1.11
ARL2 and BART enter mitochondria and bind the adenine nucleotide transporter. Mol Biol Cell (2002) 1.11
Fate-mapping of the epithelial seam during palatal fusion rules out epithelial-mesenchymal transformation. Dev Biol (2005) 1.11
Mint3/X11gamma is an ADP-ribosylation factor-dependent adaptor that regulates the traffic of the Alzheimer's Precursor protein from the trans-Golgi network. Mol Biol Cell (2007) 1.09
Protist homologs of the meiotic Spo11 gene and topoisomerase VI reveal an evolutionary history of gene duplication and lineage-specific loss. Mol Biol Evol (2007) 1.09
Do Salmonella carry spare tyres? Trends Microbiol (2008) 1.07
Genetic interactions link ARF1, YPT31/32 and TRS130. Yeast (2002) 1.07
Accelerated mutation accumulation in asexual lineages of a freshwater snail. Mol Biol Evol (2009) 1.05
Cytosolic Arl2 is complexed with cofactor D and protein phosphatase 2A. J Biol Chem (2003) 1.05
Expression patterns of the Tmem16 gene family during cephalic development in the mouse. Gene Expr Patterns (2008) 1.04
In the limb AER Bmp2 and Bmp4 are required for dorsal-ventral patterning and interdigital cell death but not limb outgrowth. Dev Biol (2009) 1.01
A genomic survey of the fish parasite Spironucleus salmonicida indicates genomic plasticity among diplomonads and significant lateral gene transfer in eukaryote genome evolution. BMC Genomics (2007) 1.01
Epigenetic patterns maintained in early Caenorhabditis elegans embryos can be established by gene activity in the parental germ cells. PLoS Genet (2011) 1.00
Analysis of the regulation of lin-41 during chick and mouse limb development. Dev Dyn (2005) 1.00