Published in Free Radic Biol Med on January 01, 2005
Regulation of autophagy by extracellular signal-regulated protein kinases during 1-methyl-4-phenylpyridinium-induced cell death. Am J Pathol (2007) 3.29
Autophagic stress in neuronal injury and disease. J Neuropathol Exp Neurol (2006) 2.17
Expression of Nrf2 in neurodegenerative diseases. J Neuropathol Exp Neurol (2007) 1.95
Dynamic regulation of PGC-1alpha localization and turnover implicates mitochondrial adaptation in calorie restriction and the stress response. Aging Cell (2007) 1.87
Beclin 1-independent pathway of damage-induced mitophagy and autophagic stress: implications for neurodegeneration and cell death. Autophagy (2007) 1.79
Myocardial AKT: the omnipresent nexus. Physiol Rev (2011) 1.76
Autophagy and the degradation of mitochondria. Mitochondrion (2010) 1.75
The role of mitochondria in protection of the heart by preconditioning. Biochim Biophys Acta (2007) 1.74
The ERK Cascade: Distinct Functions within Various Subcellular Organelles. Genes Cancer (2011) 1.74
A novel mitochondrial matrix serine/threonine protein phosphatase regulates the mitochondria permeability transition pore and is essential for cellular survival and development. Genes Dev (2007) 1.49
Mitochondria and Ca(2+) signaling: old guests, new functions. Pflugers Arch (2007) 1.47
Hsp27 inhibits Bax activation and apoptosis via a phosphatidylinositol 3-kinase-dependent mechanism. J Biol Chem (2008) 1.44
PTEN, the Achilles' heel of myocardial ischaemia/reperfusion injury? Br J Pharmacol (2007) 1.39
SirT1 enhances survival of human osteoarthritic chondrocytes by repressing protein tyrosine phosphatase 1B and activating the insulin-like growth factor receptor pathway. Arthritis Rheum (2010) 1.33
6-Hydroxydopamine induces mitochondrial ERK activation. Free Radic Biol Med (2007) 1.32
Constitutive ERK MAPK activity regulates macrophage ATP production and mitochondrial integrity. J Immunol (2008) 1.30
Mitochondrial c-Jun N-terminal kinase (JNK) signaling initiates physiological changes resulting in amplification of reactive oxygen species generation. J Biol Chem (2011) 1.29
Mitochondrial phosphoproteome revealed by an improved IMAC method and MS/MS/MS. Mol Cell Proteomics (2007) 1.27
Functional repression of cAMP response element in 6-hydroxydopamine-treated neuronal cells. J Biol Chem (2006) 1.25
Phosphorylation and kinetics of mammalian cytochrome c oxidase. Mol Cell Proteomics (2008) 1.24
Phosphoproteome analysis of functional mitochondria isolated from resting human muscle reveals extensive phosphorylation of inner membrane protein complexes and enzymes. Mol Cell Proteomics (2010) 1.20
Manganese superoxide dismutase protects against 6-hydroxydopamine injury in mouse brains. J Biol Chem (2005) 1.19
Modulation of mitochondrial protein phosphorylation by soluble adenylyl cyclase ameliorates cytochrome oxidase defects. EMBO Mol Med (2009) 1.17
Apoptosis inducing factor mediates caspase-independent 1-methyl-4-phenylpyridinium toxicity in dopaminergic cells. J Neurochem (2005) 1.16
Live free or die: tales of homeless (cells) in cancer. Am J Pathol (2010) 1.15
Mitochondrial energy and redox signaling in plants. Antioxid Redox Signal (2013) 1.12
Insulin-like actions of glucagon-like peptide-1: a dual receptor hypothesis. Trends Endocrinol Metab (2009) 1.10
Mitochondrial integrity: preservation through Akt/Pim-1 kinase signaling in the cardiomyocyte. Expert Rev Cardiovasc Ther (2009) 1.10
The human PINK1 locus is regulated in vivo by a non-coding natural antisense RNA during modulation of mitochondrial function. BMC Genomics (2007) 1.10
Tickled PINK1: mitochondrial homeostasis and autophagy in recessive Parkinsonism. Biochim Biophys Acta (2009) 1.09
Location, location, location: altered transcription factor trafficking in neurodegeneration. J Neuropathol Exp Neurol (2007) 1.09
Nuclear and mitochondrial signalling Akts in cardiomyocytes. Cardiovasc Res (2009) 1.09
14-3-3zeta contributes to tyrosine hydroxylase activity in MN9D cells: localization of dopamine regulatory proteins to mitochondria. J Biol Chem (2009) 1.09
Identification of novel modulators of mitochondrial function by a genome-wide RNAi screen in Drosophila melanogaster. Genome Res (2007) 1.07
MnSOD in oxidative stress response-potential regulation via mitochondrial protein influx. Antioxid Redox Signal (2013) 1.04
Clinical and technical phosphoproteomic research. Proteome Sci (2011) 1.04
Mitochondrial targets for stroke: focusing basic science research toward development of clinically translatable therapeutics. Stroke (2009) 1.01
Akt activation improves oxidative phosphorylation in renal proximal tubular cells following nephrotoxicant injury. Am J Physiol Renal Physiol (2007) 1.00
The energy-redox axis in aging and age-related neurodegeneration. Adv Drug Deliv Rev (2009) 0.98
Mitochondrial kinases in Parkinson's disease: converging insights from neurotoxin and genetic models. Mitochondrion (2009) 0.98
Dual specificity phosphatases 18 and 21 target to opposing sides of the mitochondrial inner membrane. J Biol Chem (2008) 0.97
Phosphorylation of the F(1)F(o) ATP synthase beta subunit: functional and structural consequences assessed in a model system. Circ Res (2009) 0.97
Crosstalk Between Endoplasmic Reticulum Stress, Oxidative Stress, and Autophagy: Potential Therapeutic Targets for Acute CNS Injuries. Mol Neurobiol (2014) 0.95
Peroxidase mechanism of lipid-dependent cross-linking of synuclein with cytochrome C: protection against apoptosis versus delayed oxidative stress in Parkinson disease. J Biol Chem (2009) 0.94
Redox signaling and protein phosphorylation in mitochondria: progress and prospects. J Bioenerg Biomembr (2009) 0.93
Cellular stress-induced up-regulation of FMRP promotes cell survival by modulating PI3K-Akt phosphorylation cascades. J Biomed Sci (2011) 0.91
Multiple phosphorylations of cytochrome c oxidase and their functions. Proteomics (2012) 0.90
Anti-apoptotic actions of vasopressin in H32 neurons involve MAP kinase transactivation and Bad phosphorylation. Exp Neurol (2008) 0.88
Mitochondrial protein phosphorylation as a regulatory modality: implications for mitochondrial dysfunction in heart failure. Congest Heart Fail (2011) 0.87
Oxidative stress induced mitochondrial protein kinase A mediates cytochrome c oxidase dysfunction. PLoS One (2013) 0.86
Mitochondrial protein phosphorylation: instigator or target of lipotoxicity? Trends Endocrinol Metab (2009) 0.86
Gonadotropin-regulated testicular helicase (DDX25), an essential regulator of spermatogenesis, prevents testicular germ cell apoptosis. J Biol Chem (2008) 0.86
Adenosine 3',5'-cyclic monophosphate (cAMP)-dependent phosphoregulation of mitochondrial complex I is inhibited by nucleoside reverse transcriptase inhibitors. Toxicol Appl Pharmacol (2007) 0.84
Downregulation of the mitochondrial phosphatase PTPMT1 is sufficient to promote cancer cell death. PLoS One (2013) 0.84
Technical phosphoproteomic and bioinformatic tools useful in cancer research. J Clin Bioinforma (2011) 0.83
RACK-1 overexpression protects against goniothalamin-induced cell death. Toxicol Lett (2009) 0.82
An integrated mitochondrial ROS production and scavenging model: implications for heart failure. Biophys J (2013) 0.81
Wedelolactone, a medicinal plant-derived coumestan, induces caspase-dependent apoptosis in prostate cancer cells via downregulation of PKCε without inhibiting Akt. Int J Oncol (2012) 0.81
Temozolomide-mediated DNA methylation in human myeloid precursor cells: differential involvement of intrinsic and extrinsic apoptotic pathways. Clin Cancer Res (2013) 0.81
Functional characterization of a mitochondrial Ser/Thr protein phosphatase in cell death regulation. Methods Enzymol (2009) 0.81
Apparent PKA activity responds to intermittent hypoxia in bone cells: a redox pathway? Am J Physiol Heart Circ Physiol (2010) 0.81
Low molecular weight, non-peptidic agonists of TrkA receptor with NGF-mimetic activity. Cell Death Dis (2012) 0.80
Selective targeting of c-Abl via a cryptic mitochondrial targeting signal activated by cellular redox status in leukemic and breast cancer cells. Pharm Res (2012) 0.80
Plant mitochondrial retrograde signaling: post-translational modifications enter the stage. Front Plant Sci (2012) 0.80
Hyperglycemia / hypoglycemia-induced mitochondrial dysfunction and cerebral ischemic damage in diabetics. Metab Brain Dis (2014) 0.79
Quantitative proteomics discloses MET expression in mitochondria as a direct target of MET kinase inhibitor in cancer cells. Mol Cell Proteomics (2010) 0.79
Novel Ser/Thr protein phosphatases in cell death regulation. Physiology (Bethesda) (2012) 0.79
Mechanistic evaluation of a novel small molecule targeting mitochondria in pancreatic cancer cells. PLoS One (2013) 0.79
Protein Kinase A Subunit α Catalytic and A Kinase Anchoring Protein 79 in Human Placental Mitochondria. Open Biochem J (2012) 0.78
Respiratory supercomplexes: plasticity and implications. Front Biosci (Landmark Ed) (2015) 0.77
Thermal sensitivity of mitochondrial respiration efficiency and protein phosphorylation in the clam Mercenaria mercenaria. Mar Biotechnol (NY) (2009) 0.77
Host-pathogen interactions in malaria: cross-kingdom signaling and mitochondrial regulation. Curr Opin Immunol (2015) 0.76
A new mitochondrial pool of cyclin E, regulated by Drp1, is linked to cell-density-dependent cell proliferation. J Cell Sci (2015) 0.76
CDK1 Enhances Mitochondrial Bioenergetics for Radiation-Induced DNA Repair. Cell Rep (2015) 0.75
AKAP350C targets to mitochondria via a novel amphipathic alpha helical domain. Cell Logist (2014) 0.75
Liraglutide attenuates partial warm ischemia-reperfusion injury in rat livers. Naunyn Schmiedebergs Arch Pharmacol (2016) 0.75
Alterations in the content of metal elements and fatty acids in hepatic ischaemia-reperfusion: induction of apoptotic and necrotic cell death. Dig Dis Sci (2007) 0.75
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy (2007) 20.92
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Loss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fission. J Biol Chem (2009) 4.90
Role of autophagy in G2019S-LRRK2-associated neurite shortening in differentiated SH-SY5Y cells. J Neurochem (2008) 3.86
Regulation of autophagy by extracellular signal-regulated protein kinases during 1-methyl-4-phenylpyridinium-induced cell death. Am J Pathol (2007) 3.29
A comprehensive glossary of autophagy-related molecules and processes (2nd edition). Autophagy (2011) 2.02
Bioenergetics of neurons inhibit the translocation response of Parkin following rapid mitochondrial depolarization. Hum Mol Genet (2010) 1.99
Expression of Nrf2 in neurodegenerative diseases. J Neuropathol Exp Neurol (2007) 1.95
Regulation of the autophagy protein LC3 by phosphorylation. J Cell Biol (2010) 1.86
Localization of phosphorylated ERK/MAP kinases to mitochondria and autophagosomes in Lewy body diseases. Brain Pathol (2003) 1.75
Mitochondrially localized ERK2 regulates mitophagy and autophagic cell stress: implications for Parkinson's disease. Autophagy (2008) 1.74
Mitochondrial aberrations in mucolipidosis Type IV. J Biol Chem (2006) 1.61
In vivo effects of single intra-articular injection of 0.5% bupivacaine on articular cartilage. J Bone Joint Surg Am (2010) 1.59
Autophagy, mitochondria and cell death in lysosomal storage diseases. Autophagy (2007) 1.55
Starving neurons show sex difference in autophagy. J Biol Chem (2008) 1.49
Cytoplasmic aggregates of phosphorylated extracellular signal-regulated protein kinases in Lewy body diseases. Am J Pathol (2002) 1.43
Autophagy is increased after traumatic brain injury in mice and is partially inhibited by the antioxidant gamma-glutamylcysteinyl ethyl ester. J Cereb Blood Flow Metab (2007) 1.33
6-Hydroxydopamine induces mitochondrial ERK activation. Free Radic Biol Med (2007) 1.32
Hippocampal long-term potentiation, memory, and longevity in mice that overexpress mitochondrial superoxide dismutase. Neurobiol Learn Mem (2006) 1.32
Autophagy in neuroprotection and neurodegeneration: A question of balance. Future Neurol (2008) 1.31
Functional repression of cAMP response element in 6-hydroxydopamine-treated neuronal cells. J Biol Chem (2006) 1.25
Optical coherence tomography grading correlates with MRI T2 mapping and extracellular matrix content. J Orthop Res (2010) 1.23
Nuclear transport, oxidative stress, and neurodegeneration. Int J Clin Exp Pathol (2011) 1.22
The p75 neurotrophin receptor can induce autophagy and death of cerebellar Purkinje neurons. J Neurosci (2004) 1.21
Manganese superoxide dismutase protects against 6-hydroxydopamine injury in mouse brains. J Biol Chem (2005) 1.19
Arthroscopic microscopy of articular cartilage using optical coherence tomography. Am J Sports Med (2004) 1.17
After the banquet: mitochondrial biogenesis, mitophagy, and cell survival. Autophagy (2013) 1.17
Mitochondrial dysfunction in Parkinson's disease. J Alzheimers Dis (2010) 1.16
Beyond the mitochondrion: cytosolic PINK1 remodels dendrites through protein kinase A. J Neurochem (2013) 1.16
Mutant LRRK2 elicits calcium imbalance and depletion of dendritic mitochondria in neurons. Am J Pathol (2012) 1.16
Peroxiredoxin-2 protects against 6-hydroxydopamine-induced dopaminergic neurodegeneration via attenuation of the apoptosis signal-regulating kinase (ASK1) signaling cascade. J Neurosci (2011) 1.13
Autophagy is increased in mice after traumatic brain injury and is detectable in human brain after trauma and critical illness. Autophagy (2007) 1.12
Mitochondrial quality control: insights on how Parkinson's disease related genes PINK1, parkin, and Omi/HtrA2 interact to maintain mitochondrial homeostasis. J Bioenerg Biomembr (2009) 1.11
A novel transferrin/TfR2-mediated mitochondrial iron transport system is disrupted in Parkinson's disease. Neurobiol Dis (2009) 1.11
PINK1 deficiency impairs mitochondrial homeostasis and promotes lung fibrosis. J Clin Invest (2014) 1.06
ATP13A2 regulates mitochondrial bioenergetics through macroautophagy. Neurobiol Dis (2011) 1.06
Role of reactive oxygen species in extracellular signal-regulated protein kinase phosphorylation and 6-hydroxydopamine cytotoxicity. J Biosci (2003) 1.02
Mitochondrial kinases in Parkinson's disease: converging insights from neurotoxin and genetic models. Mitochondrion (2009) 0.98
It's a cell-eat-cell world: autophagy and phagocytosis. Am J Pathol (2013) 0.95
Peroxidase mechanism of lipid-dependent cross-linking of synuclein with cytochrome C: protection against apoptosis versus delayed oxidative stress in Parkinson disease. J Biol Chem (2009) 0.94
Intracranial extramedullary hematopoiesis associated with pilocytic astrocytoma: a case report. Acta Neuropathol (2003) 0.94
Nitrite activates protein kinase A in normoxia to mediate mitochondrial fusion and tolerance to ischaemia/reperfusion. Cardiovasc Res (2013) 0.93
Monitoring mitophagy in neuronal cell cultures. Methods Mol Biol (2011) 0.93
Mitochondrial autophagy as a compensatory response to PINK1 deficiency. Autophagy (2009) 0.89
Synaptic dysfunction in genetic models of Parkinson's disease: a role for autophagy? Neurobiol Dis (2010) 0.88
To eat or not to eat: neuronal metabolism, mitophagy, and Parkinson's disease. Antioxid Redox Signal (2011) 0.87
Chordoid glioma: a case report and molecular characterization of five cases. Brain Pathol (2008) 0.84
Human mesenchymal stem cells/multipotent stromal cells consume accumulated autophagosomes early in differentiation. Stem Cell Res Ther (2014) 0.83
Beyond mitophagy: cytosolic PINK1 as a messenger of mitochondrial health. Antioxid Redox Signal (2015) 0.82
Acanthamoeba keratitis: a clinicopathologic case report and review of the literature. Hum Pathol (2013) 0.80
Altered transcription factor trafficking in oxidatively-stressed neuronal cells. Biochim Biophys Acta (2012) 0.78
Autophagy in different flavors: dysregulated protein degradation in neurological diseases. Neurobiol Dis (2011) 0.78
Introduction. Autophagy dysregulation in neuropathology. Brain Pathol (2012) 0.76
Functional analysis of plasma alpha(2)-macroglobulin from Alzheimer's disease patients with the A2M intronic deletion. Neurobiol Dis (2003) 0.76
Mitochondria and Parkinson's disease. Parkinsons Dis (2012) 0.76
Potential clinical importance of the activation peptide of prostate-specific antigen. Int J Clin Exp Pathol (2009) 0.75
Pseudogout of the craniocervical junction. Arch Pathol Lab Med (2003) 0.75
Asymptomatic giant-cell (temporal) arteritis involving the bilateral adnexa: case report and literature review. Int J Gynecol Pathol (2007) 0.75
INTRAOCULAR SYNOVIAL SARCOMA. Retin Cases Brief Rep (2016) 0.75