Published in J Clin Invest on January 01, 2005
Cellular and molecular mechanisms of fibrosis. J Pathol (2008) 14.01
Protective and pathogenic functions of macrophage subsets. Nat Rev Immunol (2011) 12.21
Mechanisms of hepatic fibrogenesis. Gastroenterology (2008) 11.98
Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver. Physiol Rev (2008) 10.28
Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters. Nat Med (2009) 9.71
Monocyte subsets differentially employ CCR2, CCR5, and CX3CR1 to accumulate within atherosclerotic plaques. J Clin Invest (2007) 9.09
Macrophage biology in development, homeostasis and disease. Nature (2013) 8.28
Inflammatory monocytes recruited after skeletal muscle injury switch into antiinflammatory macrophages to support myogenesis. J Exp Med (2007) 7.87
Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis. Am J Pathol (2009) 7.34
Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases. J Clin Invest (2007) 6.56
Mechanisms of fibrosis: therapeutic translation for fibrotic disease. Nat Med (2012) 6.15
Liver cirrhosis. Lancet (2008) 6.11
Pericytes and perivascular fibroblasts are the primary source of collagen-producing cells in obstructive fibrosis of the kidney. Am J Pathol (2008) 5.06
Models of liver fibrosis: exploring the dynamic nature of inflammation and repair in a solid organ. J Clin Invest (2007) 4.41
Macrophages: master regulators of inflammation and fibrosis. Semin Liver Dis (2010) 4.24
Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver. Nat Cell Biol (2015) 4.08
Macrophage-derived Wnt opposes Notch signaling to specify hepatic progenitor cell fate in chronic liver disease. Nat Med (2012) 3.96
A distinct macrophage population mediates metastatic breast cancer cell extravasation, establishment and growth. PLoS One (2009) 3.86
CCR1 and CCR5 promote hepatic fibrosis in mice. J Clin Invest (2009) 3.62
Kidney injury molecule-1 is a phosphatidylserine receptor that confers a phagocytic phenotype on epithelial cells. J Clin Invest (2008) 3.59
Integrating mechanisms of pulmonary fibrosis. J Exp Med (2011) 3.57
WNT7b mediates macrophage-induced programmed cell death in patterning of the vasculature. Nature (2005) 3.44
NF-κB in the liver--linking injury, fibrosis and hepatocellular carcinoma. Nat Rev Gastroenterol Hepatol (2011) 3.28
Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME. Arch Toxicol (2013) 3.00
Antagonism of the chemokine Ccl5 ameliorates experimental liver fibrosis in mice. J Clin Invest (2010) 2.87
Macrophage Wnt7b is critical for kidney repair and regeneration. Proc Natl Acad Sci U S A (2010) 2.87
Galectin-3 expression and secretion links macrophages to the promotion of renal fibrosis. Am J Pathol (2008) 2.83
Galectin-3 regulates myofibroblast activation and hepatic fibrosis. Proc Natl Acad Sci U S A (2006) 2.75
Monocyte/macrophage suppression in CD11b diphtheria toxin receptor transgenic mice differentially affects atherogenesis and established plaques. Circ Res (2007) 2.74
Differential Ly-6C expression identifies the recruited macrophage phenotype, which orchestrates the regression of murine liver fibrosis. Proc Natl Acad Sci U S A (2012) 2.54
Selective and specific macrophage ablation is detrimental to wound healing in mice. Am J Pathol (2009) 2.45
Non-cell-autonomous tumor suppression by p53. Cell (2013) 2.40
Host response to translocated microbial products predicts outcomes of patients with HBV or HCV infection. Gastroenterology (2011) 2.39
Conditional ablation of macrophages halts progression of crescentic glomerulonephritis. Am J Pathol (2005) 2.38
CCR2 promotes hepatic fibrosis in mice. Hepatology (2009) 2.35
Systemic effects of inflammation on health during chronic HIV infection. Immunity (2013) 2.34
Liver fibrosis and repair: immune regulation of wound healing in a solid organ. Nat Rev Immunol (2014) 2.29
Macrophages and tissue injury: agents of defense or destruction? Annu Rev Pharmacol Toxicol (2011) 2.28
Fibrocytes: emerging effector cells in chronic inflammation. Nat Rev Immunol (2011) 2.26
Cell biology of ischemia/reperfusion injury. Int Rev Cell Mol Biol (2012) 2.24
Resolution-phase macrophages possess a unique inflammatory phenotype that is controlled by cAMP. Blood (2008) 2.16
Macrophage roles following myocardial infarction. Int J Cardiol (2008) 2.14
Targeting endothelium-pericyte cross talk by inhibiting VEGF receptor signaling attenuates kidney microvascular rarefaction and fibrosis. Am J Pathol (2011) 2.12
Host responses in tissue repair and fibrosis. Annu Rev Pathol (2012) 2.10
Cellular and molecular mechanisms in kidney fibrosis. J Clin Invest (2014) 2.07
Lung dendritic cells induce migration of protective T cells to the gastrointestinal tract. J Exp Med (2013) 1.99
Molecular mechanisms linking wound inflammation and fibrosis: knockdown of osteopontin leads to rapid repair and reduced scarring. J Exp Med (2008) 1.99
A transgenic mouse model of inducible macrophage depletion: effects of diphtheria toxin-driven lysozyme M-specific cell lineage ablation on wound inflammatory, angiogenic, and contractive processes. Am J Pathol (2009) 1.99
CSF-1 signaling mediates recovery from acute kidney injury. J Clin Invest (2012) 1.98
CCR2-dependent recruitment of macrophages by tumor-educated mesenchymal stromal cells promotes tumor development and is mimicked by TNFα. Cell Stem Cell (2012) 1.97
Functional contribution of elevated circulating and hepatic non-classical CD14CD16 monocytes to inflammation and human liver fibrosis. PLoS One (2010) 1.94
Studying the mononuclear phagocyte system in the molecular age. Nat Rev Immunol (2011) 1.93
Fas determines differential fates of resident and recruited macrophages during resolution of acute lung injury. Am J Respir Crit Care Med (2011) 1.92
Vascular endothelial growth factor promotes fibrosis resolution and repair in mice. Gastroenterology (2014) 1.91
Fibrosis-dependent mechanisms of hepatocarcinogenesis. Hepatology (2012) 1.91
Circulating monocytes from systemic sclerosis patients with interstitial lung disease show an enhanced profibrotic phenotype. Lab Invest (2010) 1.90
Divergent angiocrine signals from vascular niche balance liver regeneration and fibrosis. Nature (2013) 1.88
Mesenchymal stem cells: the fibroblasts' new clothes? Haematologica (2008) 1.87
The renal mononuclear phagocytic system. J Am Soc Nephrol (2011) 1.84
Wound macrophages as key regulators of repair: origin, phenotype, and function. Am J Pathol (2010) 1.83
Attenuated liver fibrosis in the absence of B cells. J Clin Invest (2005) 1.82
Heterogeneous in vivo behavior of monocyte subsets in atherosclerosis. Arterioscler Thromb Vasc Biol (2009) 1.79
MMP28 promotes macrophage polarization toward M2 cells and augments pulmonary fibrosis. J Leukoc Biol (2013) 1.78
An abundant tissue macrophage population in the adult murine heart with a distinct alternatively-activated macrophage profile. PLoS One (2012) 1.76
Transcriptomic analyses of murine resolution-phase macrophages. Blood (2011) 1.75
Activation of alveolar macrophages via the alternative pathway in herpesvirus-induced lung fibrosis. Am J Respir Cell Mol Biol (2006) 1.75
Serum amyloid P inhibits fibrosis through Fc gamma R-dependent monocyte-macrophage regulation in vivo. Sci Transl Med (2009) 1.74
Cell death and cell death responses in liver disease: mechanisms and clinical relevance. Gastroenterology (2014) 1.73
Interleukin-1 participates in the progression from liver injury to fibrosis. Am J Physiol Gastrointest Liver Physiol (2009) 1.72
Macrophages and immunologic inflammation of the kidney. Semin Nephrol (2010) 1.71
Preparing the ground for tissue regeneration: from mechanism to therapy. Nat Med (2014) 1.71
Macrophages and inflammatory mediators in chemical toxicity: a battle of forces. Chem Res Toxicol (2009) 1.70
Layer V cortical neurons require microglial support for survival during postnatal development. Nat Neurosci (2013) 1.70
Hepatic inflammation and fibrosis: functional links and key pathways. Hepatology (2015) 1.68
Liver X receptor signaling is a determinant of stellate cell activation and susceptibility to fibrotic liver disease. Gastroenterology (2010) 1.67
Macrophage phenotypes during tissue repair. J Leukoc Biol (2013) 1.67
CSF-1 signals directly to renal tubular epithelial cells to mediate repair in mice. J Clin Invest (2009) 1.66
Monocyte and macrophage heterogeneity in the heart. Circ Res (2013) 1.63
11β-hydroxysteroid dehydrogenases: intracellular gate-keepers of tissue glucocorticoid action. Physiol Rev (2013) 1.60
Activation of stem cells in hepatic diseases. Cell Tissue Res (2007) 1.59
The resolution of inflammation. Nat Rev Immunol (2012) 1.58
Renal collecting duct epithelial cells regulate inflammation in tubulointerstitial damage in mice. J Clin Invest (2011) 1.56
Monocytic suppressive cells mediate cardiovascular transplantation tolerance in mice. J Clin Invest (2010) 1.55
Fibrogenesis of parenchymal organs. Proc Am Thorac Soc (2008) 1.53
Functional role of monocytes and macrophages for the inflammatory response in acute liver injury. Front Physiol (2012) 1.49
Inflammation in alcoholic liver disease. Annu Rev Nutr (2012) 1.49
Dual role of CCR2 in the constitution and the resolution of liver fibrosis in mice. Am J Pathol (2009) 1.49
Alternative splicing of endothelial fibronectin is induced by disturbed hemodynamics and protects against hemorrhage of the vessel wall. Arterioscler Thromb Vasc Biol (2014) 1.48
Pericyte TIMP3 and ADAMTS1 modulate vascular stability after kidney injury. J Am Soc Nephrol (2012) 1.48
Human aquaporin 4281-300 is the immunodominant linear determinant in the context of HLA-DRB1*03:01: relevance for diagnosing and monitoring patients with neuromyelitis optica. Arch Neurol (2012) 1.47
Characterisation of a stereotypical cellular and extracellular adult liver progenitor cell niche in rodents and diseased human liver. Gut (2010) 1.44
Fibrosis is regulated by Th2 and Th17 responses and by dynamic interactions between fibroblasts and macrophages. Am J Physiol Gastrointest Liver Physiol (2011) 1.44
Hepatic macrophages but not dendritic cells contribute to liver fibrosis by promoting the survival of activated hepatic stellate cells in mice. Hepatology (2013) 1.40
Bone marrow stem cells and liver disease. Gut (2006) 1.40
Depletion of Foxp3+ Regulatory T Cells Promotes Profibrogenic Milieu of Cholestasis-Induced Liver Injury. Dig Dis Sci (2014) 1.40
Pharmacological inhibition of integrin alphavbeta3 aggravates experimental liver fibrosis and suppresses hepatic angiogenesis. Hepatology (2009) 1.39
Leukocytes induce epithelial to mesenchymal transition after unilateral ureteral obstruction in neonatal mice. Am J Pathol (2007) 1.39
Sonic hedgehog pathway activation is induced by acute brain injury and regulated by injury-related inflammation. J Neurosci (2009) 1.38
Stem cells, cell transplantation and liver repopulation. Biochim Biophys Acta (2007) 1.37
Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Trends Immunol (2002) 17.85
In vivo depletion of CD11c+ dendritic cells abrogates priming of CD8+ T cells by exogenous cell-associated antigens. Immunity (2002) 14.57
Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF. J Clin Invest (1998) 13.05
Picrosirius staining plus polarization microscopy, a specific method for collagen detection in tissue sections. Histochem J (1979) 8.95
The role of the macrophage in wound repair. A study with hydrocortisone and antimacrophage serum. Am J Pathol (1975) 6.42
Deactivation of macrophages by transforming growth factor-beta. Nature (1988) 5.56
Mechanisms of spontaneous resolution of rat liver fibrosis. Hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inhibitors. J Clin Invest (1998) 5.27
Diphtheria toxin receptor-mediated conditional and targeted cell ablation in transgenic mice. Nat Biotechnol (2001) 4.82
FVB/N: an inbred mouse strain preferable for transgenic analyses. Proc Natl Acad Sci U S A (1991) 4.29
Other functions, other genes: alternative activation of antigen-presenting cells. Immunity (1999) 4.15
Expression cloning of a diphtheria toxin receptor: identity with a heparin-binding EGF-like growth factor precursor. Cell (1992) 3.81
Inactivation of the lysyl oxidase gene Lox leads to aortic aneurysms, cardiovascular dysfunction, and perinatal death in mice. Circulation (2002) 3.57
Regulation of scavenger receptor CD163 expression in human monocytes and macrophages by pro- and antiinflammatory stimuli. J Leukoc Biol (2000) 3.24
Inhibition of apoptosis of activated hepatic stellate cells by tissue inhibitor of metalloproteinase-1 is mediated via effects on matrix metalloproteinase inhibition: implications for reversibility of liver fibrosis. J Biol Chem (2002) 2.88
A significant proportion of myofibroblasts are of bone marrow origin in human liver fibrosis. Gastroenterology (2004) 2.70
The inflammatory macrophage: a story of Jekyll and Hyde. Clin Sci (Lond) (2003) 2.49
Spontaneous recovery from micronodular cirrhosis: evidence for incomplete resolution associated with matrix cross-linking. Gastroenterology (2004) 2.44
Transcriptional and translational regulation of inflammatory mediator production by endogenous TGF-beta in macrophages that have ingested apoptotic cells. J Immunol (1999) 2.43
Dectin-1 expression and function are enhanced on alternatively activated and GM-CSF-treated macrophages and are negatively regulated by IL-10, dexamethasone, and lipopolysaccharide. J Immunol (2003) 2.38
FIZZ1 and Ym as tools to discriminate between differentially activated macrophages. Dev Immunol (2002) 2.36
Hepatic stellate cell behavior during resolution of liver injury. Semin Liver Dis (2001) 2.32
Normal and pathologic soft tissue remodeling: role of the myofibroblast, with special emphasis on liver and kidney fibrosis. Lab Invest (2003) 2.27
Influence of alternatively and classically activated macrophages on fibrogenic activities of human fibroblasts. Cell Immunol (2000) 2.18
Kupffer cell depletion by liposome-delivered drugs: comparative activity of intracellular clodronate, propamidine, and ethylenediaminetetraacetic acid. Hepatology (1996) 2.05
Macrophage depletion by clodronate-containing liposomes reduces neointimal formation after balloon injury in rats and rabbits. Circulation (2002) 2.01
Inhibitory effects of apoptotic cell ingestion upon endotoxin-driven myeloid dendritic cell maturation. J Immunol (2002) 2.01
Macrophages induce apoptosis in normal cells in vivo. Development (1997) 1.94
Mesangial cell apoptosis: the major mechanism for resolution of glomerular hypercellularity in experimental mesangial proliferative nephritis. J Clin Invest (1994) 1.83
Macrophages in haemopoietic and other tissues of the developing mouse detected by the monoclonal antibody F4/80. Development (1991) 1.65
The CD11b promoter directs high-level expression of reporter genes in macrophages in transgenic mice. Blood (1995) 1.61
Obstructive uropathy in the mouse: role of osteopontin in interstitial fibrosis and apoptosis. Kidney Int (1999) 1.60
Initial cytokine exposure determines function of macrophages and renders them unresponsive to other cytokines. J Immunol (1998) 1.57
Differences in angiogenic potential of classically vs alternatively activated macrophages. Immunobiology (1997) 1.44
Macrophages kill capillary cells in G1 phase of the cell cycle during programmed vascular regression. Development (1999) 1.40
MMP2 activation by collagen I and concanavalin A in cultured human hepatic stellate cells. Hepatology (1999) 1.39
Macrophages act as effectors of tissue damage in acute renal allograft rejection. Transplantation (2003) 1.32
False positive staining in the TUNEL assay to detect apoptosis in liver and intestine is caused by endogenous nucleases and inhibited by diethyl pyrocarbonate. Mol Pathol (1998) 1.20
A critical role for alveolar macrophages in elicitation of pulmonary immune fibrosis. Immunology (2000) 1.15
Decreased PMN accumulation and glomerular damage by clodronate liposome treatment in PMN-dependent anti-GBM nephritis in mice. Exp Nephrol (1997) 1.10
Effects of retinoids on the TGF-beta system and extracellular matrix in experimental glomerulonephritis. J Am Soc Nephrol (2001) 1.06
Suppression by apoptotic cells defines tumor necrosis factor-mediated induction of glomerular mesangial cell apoptosis by activated macrophages. Am J Pathol (2001) 1.05
Distinctive roles of neutrophils and monocytes in anti-thy-1 nephritis. Am J Pathol (2000) 1.05
Monocytic cell type-specific transcriptional induction of collagenase. J Clin Invest (1996) 1.02
Role of Fas (CD95) in tubulointerstitial disease induced by unilateral ureteric obstruction. Am J Physiol (1999) 1.00
Glomeruli synthesize nitrite in active Heymann nephritis; the source is infiltrating macrophages. Kidney Int (1991) 0.96
In vivo depletion of CD11c+ dendritic cells abrogates priming of CD8+ T cells by exogenous cell-associated antigens. Immunity (2002) 14.57
Macrophage-derived Wnt opposes Notch signaling to specify hepatic progenitor cell fate in chronic liver disease. Nat Med (2012) 3.96
Generation of functional human hepatic endoderm from human induced pluripotent stem cells. Hepatology (2010) 3.36
Targeting of αv integrin identifies a core molecular pathway that regulates fibrosis in several organs. Nat Med (2013) 3.35
Global risk scores and exercise testing for predicting all-cause mortality in a preventive medicine program. JAMA (2004) 3.34
Highly efficient differentiation of hESCs to functional hepatic endoderm requires ActivinA and Wnt3a signaling. Proc Natl Acad Sci U S A (2008) 2.99
Inhibition of apoptosis of activated hepatic stellate cells by tissue inhibitor of metalloproteinase-1 is mediated via effects on matrix metalloproteinase inhibition: implications for reversibility of liver fibrosis. J Biol Chem (2002) 2.88
Galectin-3 expression and secretion links macrophages to the promotion of renal fibrosis. Am J Pathol (2008) 2.83
Galectin-3 regulates myofibroblast activation and hepatic fibrosis. Proc Natl Acad Sci U S A (2006) 2.75
Monocyte/macrophage suppression in CD11b diphtheria toxin receptor transgenic mice differentially affects atherogenesis and established plaques. Circ Res (2007) 2.74
Scar-associated macrophages are a major source of hepatic matrix metalloproteinase-13 and facilitate the resolution of murine hepatic fibrosis. J Immunol (2007) 2.64
Differential Ly-6C expression identifies the recruited macrophage phenotype, which orchestrates the regression of murine liver fibrosis. Proc Natl Acad Sci U S A (2012) 2.54
The bone marrow functionally contributes to liver fibrosis. Gastroenterology (2006) 2.52
Elastin accumulation is regulated at the level of degradation by macrophage metalloelastase (MMP-12) during experimental liver fibrosis. Hepatology (2012) 2.52
Conditional macrophage ablation demonstrates that resident macrophages initiate acute peritoneal inflammation. J Immunol (2005) 2.50
Spontaneous recovery from micronodular cirrhosis: evidence for incomplete resolution associated with matrix cross-linking. Gastroenterology (2004) 2.44
Conditional ablation of macrophages halts progression of crescentic glomerulonephritis. Am J Pathol (2005) 2.38
Regulation of alternative macrophage activation by galectin-3. J Immunol (2008) 2.28
Macrophage therapy for murine liver fibrosis recruits host effector cells improving fibrosis, regeneration, and function. Hepatology (2011) 2.27
Ly6Chi monocytes direct alternatively activated profibrotic macrophage regulation of lung fibrosis. Am J Respir Crit Care Med (2011) 2.15
Regulation of transforming growth factor-β1-driven lung fibrosis by galectin-3. Am J Respir Crit Care Med (2011) 2.09
Multiple organ engraftment by bone-marrow-derived myofibroblasts and fibroblasts in bone-marrow-transplanted mice. Stem Cells (2003) 2.03
Dermal β-catenin activity in response to epidermal Wnt ligands is required for fibroblast proliferation and hair follicle initiation. Development (2012) 1.89
Type I collagen promotes the malignant phenotype of pancreatic ductal adenocarcinoma. Clin Cancer Res (2004) 1.83
Liver fibrosis: cellular mechanisms of progression and resolution. Clin Sci (Lond) (2007) 1.77
Inhibition of inhibitor of kappaB kinases stimulates hepatic stellate cell apoptosis and accelerated recovery from rat liver fibrosis. Gastroenterology (2005) 1.73
Expression of matrix metalloproteinase-2 and -14 persists during early resolution of experimental liver fibrosis and might contribute to fibrolysis. Liver Int (2004) 1.69
Sox2 is required for maintenance and differentiation of bronchiolar Clara, ciliated, and goblet cells. PLoS One (2009) 1.69
WNT signaling drives cholangiocarcinoma growth and can be pharmacologically inhibited. J Clin Invest (2015) 1.68
Matrix stiffness modulates proliferation, chemotherapeutic response, and dormancy in hepatocellular carcinoma cells. Hepatology (2011) 1.65
Unbiased screening of polymer libraries to define novel substrates for functional hepatocytes with inducible drug metabolism. Stem Cell Res (2010) 1.62
Engagement of alphavbeta3 integrin regulates proliferation and apoptosis of hepatic stellate cells. J Biol Chem (2004) 1.59
Modeling liver fibrosis in rodents. Methods Mol Med (2005) 1.57
Nuclear factor-kappaB1 (p50) limits the inflammatory and fibrogenic responses to chronic injury. Am J Pathol (2005) 1.53
Relaxin modulates human and rat hepatic myofibroblast function and ameliorates portal hypertension in vivo. Hepatology (2014) 1.52
Hepatic changes in the failing Fontan circulation. Heart (2006) 1.48
Characterisation of a stereotypical cellular and extracellular adult liver progenitor cell niche in rodents and diseased human liver. Gut (2010) 1.44
HGF and SDF-1-mediated mobilization of CD133+ BMSC for hepatic regeneration following extensive liver resection. Liver Int (2013) 1.42
Adult stem cell plasticity. J Pathol (2002) 1.33
The sources of parenchymal regeneration after chronic hepatocellular liver injury in mice. Hepatology (2006) 1.33
Progress and future challenges in stem cell-derived liver technologies. Am J Physiol Gastrointest Liver Physiol (2009) 1.32
Basement membrane-like matrix inhibits proliferation and collagen synthesis by activated rat hepatic stellate cells: evidence for matrix-dependent deactivation of stellate cells. Matrix Biol (2003) 1.32
Developing high-fidelity hepatotoxicity models from pluripotent stem cells. Stem Cells Transl Med (2013) 1.27
Resident pleural macrophages are key orchestrators of neutrophil recruitment in pleural inflammation. Am J Respir Crit Care Med (2005) 1.22
Bone marrow injection stimulates hepatic ductular reactions in the absence of injury via macrophage-mediated TWEAK signaling. Proc Natl Acad Sci U S A (2013) 1.20
Reversal of fibrosis: no longer a pipe dream? Clin Liver Dis (2006) 1.18
Persistence of functional hepatocyte-like cells in immune-compromised mice. Liver Int (2010) 1.18
The induction of macrophage hemeoxygenase-1 is protective during acute kidney injury in aging mice. Kidney Int (2011) 1.16
Reversibility of liver fibrosis. Ann Hepatol (2009) 1.16
CD133+ cancer stem-like cells in small cell lung cancer are highly tumorigenic and chemoresistant but sensitive to a novel neuropeptide antagonist. Cancer Res (2014) 1.12
CINC-1 is an acute-phase protein induced by focal brain injury causing leukocyte mobilization and liver injury. FASEB J (2003) 1.11
The inhibitory role of stromal cell mesenchyme on human embryonic stem cell hepatocyte differentiation is overcome by Wnt3a treatment. Cloning Stem Cells (2008) 1.09
A two-way communication between microglial cells and angiogenic sprouts regulates angiogenesis in aortic ring cultures. PLoS One (2011) 1.09
The comparison between conditioned media and serum-free media in human embryonic stem cell culture and differentiation. Cell Reprogram (2010) 1.08
The desmoplastic reaction surrounding hepatic colorectal adenocarcinoma metastases aids tumor growth and survival via alphav integrin ligation. Clin Cancer Res (2008) 1.08
Accurate prediction of drug-induced liver injury using stem cell-derived populations. Stem Cells Transl Med (2013) 1.07
Remodelling of extracellular matrix is a requirement for the hepatic progenitor cell response. Gut (2010) 1.05
Emerging therapies for liver fibrosis. Dig Dis (2006) 1.04
Macrophages: central regulators of hepatic fibrogenesis and fibrosis resolution. J Hepatol (2012) 1.04
p75 Neurotrophin receptor signaling regulates hepatic myofibroblast proliferation and apoptosis in recovery from rodent liver fibrosis. Hepatology (2009) 1.04
Wntless is required for peripheral lung differentiation and pulmonary vascular development. Dev Biol (2013) 1.03
11β-Hydroxysteroid dehydrogenase type 1, but not type 2, deficiency worsens acute inflammation and experimental arthritis in mice. Endocrinology (2011) 1.03
Increased liver pathology in hepatitis C virus transgenic mice expressing the hepatitis B virus X protein. Virology (2006) 1.02
Hepatocytes express nerve growth factor during liver injury: evidence for paracrine regulation of hepatic stellate cell apoptosis. Am J Pathol (2003) 1.02
Liver development, regeneration, and carcinogenesis. J Biomed Biotechnol (2010) 1.02
SUMOylation of HNF4α regulates protein stability and hepatocyte function. J Cell Sci (2012) 1.01
High calorie diet triggers hypothalamic angiopathy. Mol Metab (2012) 1.01
Impaired proteolysis of collagen I inhibits proliferation of hepatic stellate cells: implications for regulation of liver fibrosis. J Biol Chem (2006) 1.00
Differentiation of progenitors in the liver: a matter of local choice. J Clin Invest (2013) 1.00
Increased angiogenesis protects against adipose hypoxia and fibrosis in metabolic disease-resistant 11β-hydroxysteroid dehydrogenase type 1 (HSD1)-deficient mice. J Biol Chem (2011) 0.99
Nitric oxide is an important mediator of renal tubular epithelial cell death in vitro and in murine experimental hydronephrosis. Am J Pathol (2006) 0.99
Prospects for stem cell transplantation in the treatment of hepatic disease. Liver Transpl (2010) 0.97
Targeted treatments for cirrhosis. Expert Opin Ther Targets (2004) 0.97
Hepatic fibrogenesis: from within and outwith. Toxicology (2008) 0.97
Unexpectedly high incidence of indigenous acute hepatitis E within South Hampshire: time for routine testing? J Med Virol (2008) 0.96
The anti-inflammatory actions of angiopoietin-1. EXS (2005) 0.95
Suppression of epithelial-to-mesenchymal transitioning enhances ex vivo reprogramming of human exocrine pancreatic tissue toward functional insulin-producing β-like cells. Diabetes (2013) 0.95
Active matrix metalloproteinase-2 promotes apoptosis of hepatic stellate cells via the cleavage of cellular N-cadherin. Liver Int (2009) 0.93