Published in J Am Chem Soc on January 19, 2005
Copper active sites in biology. Chem Rev (2014) 1.90
Structural and mechanistic insights into the oxy form of tyrosinase from molecular dynamics simulations. J Biol Inorg Chem (2009) 0.81
Structural diversity in the dandelion (Taraxacum officinale) polyphenol oxidase family results in different responses to model substrates. PLoS One (2014) 0.81
Conformational equilibria in monomeric alpha-synuclein at the single-molecule level. PLoS Biol (2008) 1.37
Broken helix in vesicle and micelle-bound alpha-synuclein: insights from site-directed spin labeling-EPR experiments and MD simulations. J Am Chem Soc (2008) 1.36
Kinetic and structural analysis of the early oxidation products of dopamine: analysis of the interactions with alpha-synuclein. J Biol Chem (2007) 1.34
A topological model of the interaction between alpha-synuclein and sodium dodecyl sulfate micelles. Biochemistry (2005) 1.33
Structural insights on physiological functions and pathological effects of alpha-synuclein. FASEB J (2008) 1.32
Characterization of SLAC: a small laccase from Streptomyces coelicolor with unprecedented activity. Protein Sci (2004) 1.23
Triggering of inflammasome by aggregated α-synuclein, an inflammatory response in synucleinopathies. PLoS One (2013) 1.11
Biochemical characterization of highly purified leucine-rich repeat kinases 1 and 2 demonstrates formation of homodimers. PLoS One (2012) 1.09
Developmental regulation of the Streptomyces lividans ram genes: involvement of RamR in regulation of the ramCSAB operon. J Bacteriol (2002) 1.07
A crystallographic study of Cys69Ala flavodoxin II from Azotobacter vinelandii: structural determinants of redox potential. Protein Sci (2005) 1.06
Pathogenic mutations shift the equilibria of alpha-synuclein single molecules towards structured conformers. Chembiochem (2009) 1.06
Dramatic modulation of electron transfer in protein complexes by crosslinking. Nat Struct Biol (2002) 1.06
LRRK2 and neuroinflammation: partners in crime in Parkinson's disease? J Neuroinflammation (2014) 1.05
Structural and morphological characterization of aggregated species of α-synuclein induced by docosahexaenoic acid. J Biol Chem (2011) 1.02
Peroxidase activity as a tool for studying the folding of c-type cytochromes. Biochemistry (2002) 1.01
GTPase activity regulates kinase activity and cellular phenotypes of Parkinson's disease-associated LRRK2. Hum Mol Genet (2012) 0.99
Interaction between alpha-synuclein and metal ions, still looking for a role in the pathogenesis of Parkinson's disease. Neuromolecular Med (2009) 0.98
A random-sequential mechanism for nitrite binding and active site reduction in copper-containing nitrite reductase. J Biol Chem (2006) 0.97
Calculation of the redox potential of the protein azurin and some mutants. Chembiochem (2005) 0.93
Exosomes-associated neurodegeneration and progression of Parkinson's disease. Am J Neurodegener Dis (2012) 0.92
The emitting state of tryptophan in proteins with highly blue-shifted fluorescence. Angew Chem Int Ed Engl (2007) 0.90
MXAN analysis of the XANES energy region of a mononuclear copper complex: applications to bioinorganic systems. Inorg Chem (2005) 0.90
Structure and topology of the non-amyloid-beta component fragment of human alpha-synuclein bound to micelles: implications for the aggregation process. Protein Sci (2006) 0.89
Molecular characterization of dopamine-derived quinones reactivity toward NADH and glutathione: implications for mitochondrial dysfunction in Parkinson disease. Biochim Biophys Acta (2010) 0.89
Alpha-synuclein pore forming activity upon membrane association. Biochim Biophys Acta (2012) 0.89
Parkinson's disease and immune system: is the culprit LRRKing in the periphery? J Neuroinflammation (2012) 0.88
Dopamine-derived quinones affect the structure of the redox sensor DJ-1 through modifications at Cys-106 and Cys-53. J Biol Chem (2012) 0.88
Dopamine quinones interact with alpha-synuclein to form unstructured adducts. Biochem Biophys Res Commun (2010) 0.88
Protein film voltammetry of copper-containing nitrite reductase reveals reversible inactivation. J Am Chem Soc (2007) 0.88
Molecular insights into the interaction between alpha-synuclein and docosahexaenoic acid. J Mol Biol (2009) 0.88
Tyrosinase exacerbates dopamine toxicity but is not genetically associated with Parkinson's disease. J Neurochem (2005) 0.87
Sensitive detection of histamine using fluorescently labeled oxido-reductases. Biosens Bioelectron (2011) 0.87
Small molecules interacting with α-synuclein: antiaggregating and cytoprotective properties. Amino Acids (2013) 0.87
Ceftriaxone blocks the polymerization of α-synuclein and exerts neuroprotective effects in vitro. ACS Chem Neurosci (2013) 0.87
Measurement of a Cu-Cu distance of 26 A by a pulsed EPR method. Angew Chem Int Ed Engl (2003) 0.87
Spin-density distribution in the copper site of azurin. Chemphyschem (2006) 0.87
Effect of the protein matrix of cytochrome c in suppressing the inherent peroxidase activity of its heme prosthetic group. Chembiochem (2002) 0.86
Designed hairpin peptides interfere with amyloidogenesis pathways: fibril formation and cytotoxicity inhibition, interception of the preamyloid state. Biochemistry (2011) 0.86
The enzyme mechanism of nitrite reductase studied at single-molecule level. Proc Natl Acad Sci U S A (2008) 0.86
The role played by the alpha-helix in the unfolding pathway and stability of azurin: switching between hierarchic and nonhierarchic folding. Chembiochem (2007) 0.86
Alpha-synuclein overexpression increases dopamine toxicity in BE2-M17 cells. BMC Neurosci (2010) 0.85
Molecular evolution and phylogeny of sipunculan hemerythrins. J Mol Evol (2005) 0.85
Human SOD2 modification by dopamine quinones affects enzymatic activity by promoting its aggregation: possible implications for Parkinson's disease. PLoS One (2012) 0.85
A new type 2 copper cysteinate azurin. Involvement of an engineered exposed cysteine in copper binding through internal rearrangement. J Biol Chem (2002) 0.85
Effects of cavity-forming mutations on the internal dynamics of azurin. Biophys J (2004) 0.85
Leucine-rich repeat kinase 2 and alpha-synuclein: intersecting pathways in the pathogenesis of Parkinson's disease? Mol Neurodegener (2011) 0.85
Top-down FTICR MS for the identification of fluorescent labeling efficiency and specificity of the Cu-protein azurin. Anal Chem (2012) 0.84
Structural characterization of a high affinity mononuclear site in the copper(II)-α-synuclein complex. J Am Chem Soc (2010) 0.84
Quaternary structure and functional properties of Penaeus monodon hemocyanin. FEBS J (2005) 0.84
Structural features that govern enzymatic activity in carbonic anhydrase from a low-temperature adapted fish, Chionodraco hamatus. Biophys J (2007) 0.84
Tyrosinase-catalyzed oxidation of fluorophenols. J Biol Chem (2002) 0.84
Bidirectional catalysis by copper-containing nitrite reductase. Biochemistry (2004) 0.83
Dysfunction of dopamine homeostasis: clues in the hunt for novel Parkinson's disease therapies. FASEB J (2013) 0.83
Orientational control over nitrite reductase on modified gold electrode and its effects on the interfacial electron transfer. J Phys Chem B (2011) 0.82
Oxygen binding to tyrosinase from streptomyces antibioticus studied by laser flash photolysis. J Am Chem Soc (2005) 0.82
Genetic modulation of metalloprotein electron transfer at bare gold. Chem Commun (Camb) (2003) 0.82
α-Synuclein oligomers induced by docosahexaenoic acid affect membrane integrity. PLoS One (2013) 0.82
DJ-1 is a copper chaperone acting on SOD1 activation. J Biol Chem (2014) 0.81
Seasonal variation of trehalose and glycerol concentrations in winter snow-active insects. Cryo Letters (2009) 0.81
A model for the thermal unfolding of amicyanin. Eur Biophys J (2002) 0.81
A rearranging ligand enables allosteric control of catalytic activity in copper-containing nitrite reductase. J Mol Biol (2006) 0.81
Spectroelectrochemical investigation of intramolecular and interfacial electron-transfer rates reveals differences between nitrite reductase at rest and during turnover. J Am Chem Soc (2011) 0.81
Effect of the methionine ligand on the reorganization energy of the type-1 copper site of nitrite reductase. J Am Chem Soc (2007) 0.81
Nanoscale methods for single-molecule electrochemistry. Annu Rev Anal Chem (Palo Alto Calif) (2014) 0.81
The effect of replacing the axial methionine ligand with a lysine residue in cytochrome c-550 from Paracoccus versutus assessed by X-ray crystallography and unfolding. FEBS J (2005) 0.81
A Förster-resonance-energy transfer-based method for fluorescence detection of the protein redox state. Anal Biochem (2005) 0.81
Molecular basis of the Bohr effect in arthropod hemocyanin. J Biol Chem (2008) 0.80
Structural basis and mechanism of the inhibition of the type-3 copper protein tyrosinase from Streptomyces antibioticus by halide ions. J Biol Chem (2002) 0.80
The reaction of alpha-synuclein with tyrosinase: possible implications for Parkinson disease. J Biol Chem (2008) 0.80
Human leucine-rich repeat kinase 1 and 2: intersecting or unrelated functions? Biochem Soc Trans (2012) 0.80
Human tyrosinase produced in insect cells: a landmark for the screening of new drugs addressing its activity. Mol Biotechnol (2015) 0.80
Reconstitution of the type-1 active site of the H145G/A variants of nitrite reductase by ligand insertion. Biochemistry (2003) 0.80
Calorimetric and spectroscopic investigations of the thermal denaturation of wild type nitrite reductase. Biochim Biophys Acta (2005) 0.80
Thermal stability of wild type and disulfide bridge containing mutant of poplar plastocyanin. Biophys Chem (2004) 0.80
Trapping tyrosinase key active intermediate under turnover. Dalton Trans (2009) 0.79
Ligand loop effects on the free energy change of redox and pH-dependent equilibria in cupredoxins probed on amicyanin variants. Biochemistry (2005) 0.79
Covalent α-synuclein dimers: chemico-physical and aggregation properties. PLoS One (2012) 0.79
Investigation of Streptomyces antibioticus tyrosinase reactivity toward chlorophenols. Arch Biochem Biophys (2010) 0.79
Copper(I)-α-synuclein interaction: structural description of two independent and competing metal binding sites. Inorg Chem (2013) 0.79
Single-molecule-level evidence for the osmophobic effect. Angew Chem Int Ed Engl (2011) 0.78
Sensitive detection of the redox state of copper proteins using fluorescence. J Biol Inorg Chem (2005) 0.78
Worm-like Ising model for protein mechanical unfolding under the effect of osmolytes. Biophys J (2012) 0.78
The ternary complex of cytochrome f and cytochrome c: identification of a second binding site and competition for plastocyanin binding. Chembiochem (2002) 0.78
Thermodynamics of the acid transition in blue copper proteins. Biochemistry (2002) 0.78
Control of metalloprotein reduction potential: compensation phenomena in the reduction thermodynamics of blue copper proteins. Biochemistry (2003) 0.78
Probing the reactivity of different forms of azurin by flavin photoreduction. FEBS J (2011) 0.78
Unsymmetrical binding modes of the HOPNO inhibitor of tyrosinase: from model complexes to the enzyme. Chemistry (2013) 0.78
Involvement of Tyr108 in the enzyme mechanism of the small laccase from Streptomyces coelicolor. J Am Chem Soc (2012) 0.78
Spectroscopic characterization of a high-potential lipo-cupredoxin found in Streptomyces coelicolor. J Am Chem Soc (2006) 0.78
The substrate-bound type 2 copper site of nitrite reductase: the nitrogen hyperfine coupling of nitrite revealed by pulsed EPR. Biochemistry (2005) 0.78
Observing the osmophobic effect in action at the single molecule level. Proteins (2011) 0.78
Kinetic stability of the peroxidase activity of unfolded cytochrome c: heme degradation and catalyst inactivation by hydrogen peroxide. Inorg Chem (2003) 0.78
Solution structure of the 162 residue C-terminal domain of human elongation factor 1Bgamma. J Biol Chem (2003) 0.78
Paramagnetic properties of the halide-bound derivatives of oxidised tyrosinase investigated by 1H NMR spectroscopy. Chemistry (2006) 0.78
The pH-dependent redox inactivation of amicyanin from Paracoccus versutus as studied by rapid protein-film voltammetry. J Biol Inorg Chem (2001) 0.78
Fluorescent cyclic voltammetry of immobilized azurin: direct observation of thermodynamic and kinetic heterogeneity. Angew Chem Int Ed Engl (2010) 0.77
Cloning, expression, purification, and spectroscopic analysis of the fragment 57-102 of human alpha-synuclein. Protein Expr Purif (2005) 0.77