Published in Blood on January 18, 2005
The B7 family member B7-H6 is a tumor cell ligand for the activating natural killer cell receptor NKp30 in humans. J Exp Med (2009) 3.17
Effect of NKG2D ligand expression on host immune responses. Immunol Rev (2010) 3.08
NCRs and DNAM-1 mediate NK cell recognition and lysis of human and mouse melanoma cell lines in vitro and in vivo. J Clin Invest (2009) 2.08
Dendritic cells release HLA-B-associated transcript-3 positive exosomes to regulate natural killer function. PLoS One (2008) 1.63
Proteasome regulation of ULBP1 transcription. J Immunol (2009) 1.61
Regulation of ligands for the activating receptor NKG2D. Immunology (2007) 1.55
Blast-derived microvesicles in sera from patients with acute myeloid leukemia suppress natural killer cell function via membrane-associated transforming growth factor-beta1. Haematologica (2011) 1.37
NKG2D in NK and T cell-mediated immunity. J Clin Immunol (2005) 1.32
Expression analysis of the ligands for the Natural Killer cell receptors NKp30 and NKp44. PLoS One (2007) 1.26
Endogenous phosphatidylcholine and a long spacer ligand stabilize the lipid-binding groove of CD1b. EMBO J (2006) 1.26
NKG2D ligands as therapeutic targets. Cancer Immun (2013) 1.26
Leukemia-induced phenotypic and functional defects in natural killer cells predict failure to achieve remission in acute myeloid leukemia. Haematologica (2014) 1.12
CD200 expression suppresses natural killer cell function and directly inhibits patient anti-tumor response in acute myeloid leukemia. Leukemia (2011) 1.07
Natural killer cell-produced IFN-γ and TNF-α induce target cell cytolysis through up-regulation of ICAM-1. J Leukoc Biol (2011) 1.02
Dynamic expression of protective CEACAM1 on melanoma cells during specific immune attack. Immunology (2008) 0.99
Fine tuning by human CD1e of lipid-specific immune responses. Proc Natl Acad Sci U S A (2011) 0.98
Dynamic shift from CD85j/ILT-2 to NKG2D NK receptor expression pattern on human decidual NK during the first trimester of pregnancy. PLoS One (2012) 0.96
Interleukin-15 enhances natural killer cell cytotoxicity in patients with acute myeloid leukemia by upregulating the activating NK cell receptors. Cancer Immunol Immunother (2009) 0.95
Natural killer cells in allogeneic transplantation: effect on engraftment, graft- versus-tumor, and graft-versus-host responses. Biol Blood Marrow Transplant (2009) 0.94
A novel self-lipid antigen targets human T cells against CD1c(+) leukemias. J Exp Med (2014) 0.93
Beyond Stressed Self: Evidence for NKG2D Ligand Expression on Healthy Cells. Curr Immunol Rev (2009) 0.91
The role of KIR genes and ligands in leukemia surveillance. Front Immunol (2013) 0.91
Evaluation of current cancer immunotherapy: hemato-oncology. Cancer J (2011) 0.88
Poly(I:C) enhances the susceptibility of leukemic cells to NK cell cytotoxicity and phagocytosis by DC. PLoS One (2011) 0.87
NKG2D and DNAM-1 activating receptors and their ligands in NK-T cell interactions: role in the NK cell-mediated negative regulation of T cell responses. Front Immunol (2013) 0.86
Enhanced interaction between natural killer cells and lung cancer cells: involvement in gefitinib-mediated immunoregulation. J Transl Med (2013) 0.85
DNaseI hypersensitivity at gene-poor, FSH dystrophy-linked 4q35.2. Nucleic Acids Res (2009) 0.85
Natural killer lysis receptor (NKLR)/NKLR-ligand matching as a novel approach for enhancing anti-tumor activity of allogeneic NK cells. PLoS One (2009) 0.85
The requirement for NKG2D in NK cell-mediated rejection of parental bone marrow grafts is determined by MHC class I expressed by the graft recipient. Blood (2010) 0.84
Methylation of NKG2D ligands contributes to immune system evasion in acute myeloid leukemia. Genes Immun (2014) 0.83
NKp44 and Natural Cytotoxicity Receptors as Damage-Associated Molecular Pattern Recognition Receptors. Front Immunol (2015) 0.82
Human acute myeloid leukemia CD34+CD38- stem cells are susceptible to allorecognition and lysis by single KIR-expressing natural killer cells. Haematologica (2009) 0.82
Treatment of a solid tumor using engineered drug-resistant immunocompetent cells and cytotoxic chemotherapy. Hum Gene Ther (2012) 0.82
A VEGFR-3 antagonist increases IFN-γ expression on low functioning NK cells in acute myeloid leukemia. J Clin Immunol (2013) 0.79
Underground Adaptation to a Hostile Environment: Acute Myeloid Leukemia vs. Natural Killer Cells. Front Immunol (2016) 0.78
An NCR1-based chimeric receptor endows T-cells with multiple anti-tumor specificities. Oncotarget (2014) 0.77
NKG2D Signaling Leads to NK Cell Mediated Lysis of Childhood AML. J Immunol Res (2015) 0.77
Matrine increases NKG2D ligand ULBP2 in K562 cells via inhibiting JAK/STAT3 pathway: a potential mechanism underlying the immunotherapy of matrine in leukemia. Am J Transl Res (2015) 0.75
IL-12, IL-15, and IL-18 pre-activated NK cells target resistant T cell acute lymphoblastic leukemia and delay leukemia development in vivo. Oncoimmunology (2017) 0.75
Role of HLA-G and NCR in protection of umbilical cord blood haematopoietic stem cells from NK cell mediated cytotoxicity. J Cell Mol Med (2011) 0.75
STAT3 signaling pathway is involved in decitabine induced biological phenotype regulation of acute myeloid leukemia cells. Am J Transl Res (2015) 0.75
Soluble MICB in Plasma and Urine Explains Population Expansions of NKG2D(+)CD4 T Cells Inpatients with Juvenile-Onset Systemic Lupus Erythematosus. Open J Immunol (2017) 0.75
Triplebody Mediates Increased Anti-Leukemic Reactivity of IL-2 Activated Donor Natural Killer (NK) Cells and Impairs Viability of Their CD33-Expressing NK Subset. Front Immunol (2017) 0.75
Chronic In Vivo Interaction of Dendritic Cells Expressing the Ligand Rae-1ε with NK Cells Impacts NKG2D Expression and Function. Immunohorizons (2017) 0.75
Human T cell receptor gammadelta cells recognize endogenous mevalonate metabolites in tumor cells. J Exp Med (2003) 3.13
High-frequency and adaptive-like dynamics of human CD1 self-reactive T cells. Eur J Immunol (2011) 2.27
Human cytomegalovirus glycoprotein UL16 causes intracellular sequestration of NKG2D ligands, protecting against natural killer cell cytotoxicity. J Exp Med (2003) 2.20
Diacylated sulfoglycolipids are novel mycobacterial antigens stimulating CD1-restricted T cells during infection with Mycobacterium tuberculosis. J Exp Med (2004) 2.06
HLA class I, NKG2D, and natural cytotoxicity receptors regulate multiple myeloma cell recognition by natural killer cells. Blood (2004) 1.95
Butyrophilin 3A1 binds phosphorylated antigens and stimulates human γδ T cells. Nat Immunol (2013) 1.95
Bacterial infections promote T cell recognition of self-glycolipids. Immunity (2005) 1.92
Prevalent expression of the immunostimulatory MHC class I chain-related molecule is counteracted by shedding in prostate cancer. J Clin Invest (2004) 1.89
NKp46 and NKG2D recognition of infected dendritic cells is necessary for NK cell activation in the human response to influenza infection. J Immunol (2007) 1.78
Human CD1-restricted T cell recognition of lipids from pollens. J Exp Med (2005) 1.78
Stroke research priorities for the next decade--A representative view of the European scientific community. Cerebrovasc Dis (2006) 1.75
Assistance of microbial glycolipid antigen processing by CD1e. Science (2005) 1.73
Activated, but not resting, T cells can be recognized and killed by syngeneic NK cells. J Immunol (2003) 1.72
Self-reported nonmusculoskeletal responses to chiropractic intervention: a multination survey. J Manipulative Physiol Ther (2005) 1.71
Differentiation-promoting drugs up-regulate NKG2D ligand expression and enhance the susceptibility of acute myeloid leukemia cells to natural killer cell-mediated lysis. Leuk Res (2007) 1.67
Human immunodeficiency virus 1 Nef protein downmodulates the ligands of the activating receptor NKG2D and inhibits natural killer cell-mediated cytotoxicity. J Gen Virol (2007) 1.63
Down-regulation of the NKG2D ligand MICA by the human cytomegalovirus glycoprotein UL142. Biochem Biophys Res Commun (2006) 1.62
UL16-binding proteins, novel MHC class I-related proteins, bind to NKG2D and activate multiple signaling pathways in primary NK cells. J Immunol (2002) 1.61
STAT3 mutations indicate the presence of subclinical T-cell clones in a subset of aplastic anemia and myelodysplastic syndrome patients. Blood (2013) 1.59
LIR-1 expression on lymphocytes, and cytomegalovirus disease in lung-transplant recipients. Lancet (2003) 1.59
IL-7 licenses activation of human liver intrasinusoidal mucosal-associated invariant T cells. J Immunol (2013) 1.57
Peroxisome-derived lipids are self antigens that stimulate invariant natural killer T cells in the thymus. Nat Immunol (2012) 1.56
A RANK/TRAF6-dependent signal transduction pathway is essential for osteoclast cytoskeletal organization and resorptive function. J Biol Chem (2002) 1.54
ULBP4 is a novel ligand for human NKG2D. Biochem Biophys Res Commun (2003) 1.47
Recognition of lipid antigens by T cells. Nat Rev Immunol (2005) 1.42
Role of NK cell-activating receptors and their ligands in the lysis of mononuclear phagocytes infected with an intracellular bacterium. J Immunol (2005) 1.39
Tenascin-C is a novel RBPJkappa-induced target gene for Notch signaling in gliomas. Cancer Res (2009) 1.34
Three-dimensional perfusion culture of human bone marrow cells and generation of osteoinductive grafts. Stem Cells (2005) 1.32
Cell surface organization of stress-inducible proteins ULBP and MICA that stimulate human NK cells and T cells via NKG2D. J Exp Med (2004) 1.32
NKG2D ligands are expressed on stressed human airway epithelial cells. Am J Physiol Lung Cell Mol Physiol (2006) 1.31
Activation of human eosinophils through leukocyte immunoglobulin-like receptor 7. Proc Natl Acad Sci U S A (2003) 1.30
Dynamic assessment of right ventricular volumes and function by real-time three-dimensional echocardiography: a comparison study with magnetic resonance imaging in 100 adult patients. J Am Soc Echocardiogr (2010) 1.27
Clonal heterogeneity in polycythemia vera patients with JAK2 exon12 and JAK2-V617F mutations. Blood (2008) 1.27
NK cells lyse T regulatory cells that expand in response to an intracellular pathogen. J Immunol (2008) 1.26
Mycolic acids constitute a scaffold for mycobacterial lipid antigens stimulating CD1-restricted T cells. Chem Biol (2009) 1.26
Endogenous phosphatidylcholine and a long spacer ligand stabilize the lipid-binding groove of CD1b. EMBO J (2006) 1.26
Intracellular retention of the MHC class I-related chain B ligand of NKG2D by the human cytomegalovirus UL16 glycoprotein. J Immunol (2003) 1.21
Synthesis and biological evaluation of alpha-galactosylceramide (KRN7000) and isoglobotrihexosylceramide (iGb3). Bioorg Med Chem Lett (2006) 1.19
Differential alteration of lipid antigen presentation to NKT cells due to imbalances in lipid metabolism. Eur J Immunol (2007) 1.19
CD1a and MHC class I follow a similar endocytic recycling pathway. Traffic (2008) 1.10
Soluble ULBP suppresses natural killer cell activity via down-regulating NKG2D expression. Cell Immunol (2006) 1.09
The HOX gene network in hepatocellular carcinoma. Int J Cancer (2011) 1.07
Good manufacturing practice-compliant cell sorting and large-scale expansion of single KIR-positive alloreactive human natural killer cells for multiple infusions to leukemia patients. Cytotherapy (2010) 1.07
Point-of-care assays for tuberculosis: role of nanotechnology/microfluidics. Biotechnol Adv (2013) 1.06
Recognition of pollen-derived phosphatidyl-ethanolamine by human CD1d-restricted gamma delta T cells. J Allergy Clin Immunol (2006) 1.04
The co-expression of activating and inhibitory leukocyte immunoglobulin-like receptors in rheumatoid synovium. Am J Pathol (2002) 1.02
Dysregulation of the host mevalonate pathway during early bacterial infection activates human TCR gamma delta cells. Eur J Immunol (2008) 1.00
Intrathymic expression of Flt3 ligand enhances thymic recovery after irradiation. J Exp Med (2008) 0.99
Reconstitution of dendritic and natural killer-cell subsets after allogeneic stem cell transplantation: effects of endogenous flt3 ligand. Blood (2004) 0.99
Fine tuning by human CD1e of lipid-specific immune responses. Proc Natl Acad Sci U S A (2011) 0.98
Human NK cell development in NOD/SCID mice receiving grafts of cord blood CD34+ cells. Blood (2003) 0.98
Fatty acyl structures of mycobacterium tuberculosis sulfoglycolipid govern T cell response. J Immunol (2009) 0.98
Functional CD1a is stabilized by exogenous lipids. Eur J Immunol (2006) 0.98
Gene silencing by lentivirus-mediated delivery of siRNA in human CD34+ cells. Blood (2004) 0.97
Novel insights into lipid antigen presentation. Trends Immunol (2012) 0.97
Synthesis of alpha-galactosyl ceramide (KRN7000) and analogues thereof via a common precursor and their preliminary biological assessment. J Org Chem (2008) 0.95
Invariant natural killer T cells: linking inflammation and neovascularization in human atherosclerosis. Eur J Immunol (2010) 0.95
ULBPs, human ligands of the NKG2D receptor, stimulate tumor immunity with enhancement by IL-15. Blood (2006) 0.94
NKG2D splice variants: a reexamination of adaptor molecule associations. Immunogenetics (2006) 0.92
Presentation of lipid antigens to T cells. Immunol Lett (2008) 0.91
In situ correlation of cytokine secretion and apoptosis in Helicobacter pylori-associated gastritis. Am J Physiol Gastrointest Liver Physiol (2002) 0.91
Genetic control of tolerance to type II collagen and development of arthritis in an autologous collagen-induced arthritis model. J Immunol (2003) 0.90
The role of innate immunity in autoimmunity. J Exp Med (2004) 0.89
Mycobacteria exploit p38 signaling to affect CD1 expression and lipid antigen presentation by human dendritic cells. Infect Immun (2009) 0.88
Crystal structure of human CD1e reveals a groove suited for lipid-exchange processes. Proc Natl Acad Sci U S A (2011) 0.87
The cellular and biochemical rules of lipid antigen presentation. Eur J Immunol (2009) 0.87
Structural reorganization of the antigen-binding groove of human CD1b for presentation of mycobacterial sulfoglycolipids. Proc Natl Acad Sci U S A (2011) 0.86
Spontaneous mutations in the human CMV HLA class I homologue UL18 affect its binding to the inhibitory receptor LIR-1/ILT2/CD85j. Eur J Immunol (2006) 0.86
Early recycling compartment trafficking of CD1a is essential for its intersection and presentation of lipid antigens. J Immunol (2009) 0.86
Post-transcriptional regulation of ULBP1 ligand for the activating immunoreceptor NKG2D involves 3' untranslated region. Hum Immunol (2011) 0.85